In this episode, Dr. Joanna Hairy joins me to talk about her new book, Lost Connections: Uncovering the Real Causes of Depression and Anxiousness and the Real Solutions. She talks about her own experience with depression, how she overcame it, and why she thinks we should all be better at dealing with it. She also talks about why we have an anxiety and depression epidemic and why we need to do something about it. It's a really important episode and I hope you enjoy it as much as I did making it. If you're struggling with your own mental health, or know someone who is, please talk to a doctor if you can. I understand that being able to see a doctor and receive treatment is a privilege, not a right, and it's important that we all get the care that we need in order to make the most of our mental health. I hope this episode gives you some insight into what you can do to improve your mental health and get the help you need. Thank you for listening and supporting this podcast. I really appreciate it. I know I do too. -Jono Hairy and I'm so grateful to have her on the podcast. Thanks Jono. Jono is a really good friend of mine and I really enjoyed this episode. I hope that you enjoy this episode and that it resonates with you! - Jono and I have a wonderful Christmas and New Years Eve. Love you, Jono xo - Caitie (and Happy Holidays! - EJ xx <3 - Tom Bells Thankyou Jono Jonos Joanna Caitie's new book is out next week Jonathan Hairy's book is is out now Don't forget to check out the book, Jana Hairy is out in the next episode, The Real Connections . Joni's new album is out soon, Thank you Jono's book by Jana's book, "Lost Connections, Uncover the Real Cause of Depression & Anxiety and The Real Solutions, by The Real Problem? : , I'm looking forward to seeing you in the new episode of the podcast next week! by Jono s book, The Real Cause Of Depression and Anxiety and Anxiety, is available on Amazon Hope you like it?
00:00:09.000You are literally the first person to ever say my name.
00:00:11.000I was saying to your friend that I once waited for six hours with a broken arm in an emergency room because they were calling for Joanna Hairy to come forward.
00:00:17.000So anyone who gets my name better than that is fine by me.
00:00:18.000Didn't you just assume that was you when you heard Joanna Hairy?
00:00:21.000To be fair, I had a broken arm and I was lying there like weeping and being like, fuck, someone help me.
00:01:26.000And after 13 years of it, I thought, right, I need to understand what's really going on here.
00:01:29.000So I ended up going on this big, long journey over 40,000 miles, interviewing the leading experts in the world on what causes depression and anxiety and what solves them.
00:01:39.000We've told a ridiculously simplistic story to people about what depression is and how to solve it.
00:01:45.000Until I was a teenager and I went to my doctor, I thought depression was all in my head, meaning you're just being weak, you're being a pussy, basically.
00:01:53.000And then the next 13 years, I thought it was all in my head, meaning, you know, it's a chemical imbalance in your brain.
00:01:58.000What I discovered is the overwhelming evidence from the World Health Organization leading medical body in the world and loads of other places is there are real biological factors that can make you more sensitive to this stuff.
00:02:08.000But the causes of depression and anxiety are overwhelmingly in the way we're living.
00:02:11.000There are these nine causes of depression and anxiety for which I could find scientific evidence, seven of which are in the way we're living, and some of which are rising, which explains this kind of epidemic.
00:02:20.000And that opens up a whole different way of finding solutions Now when you were young and you were experiencing depression, how would you categorize it?
00:02:29.000Like what how would you describe it if you had to describe it to someone who didn't understand depression?
00:02:34.000Try to keep this about a fist away from your face.
00:02:37.000I think depression is despair spreading.
00:02:43.000Everyone has moments of hopelessness in their lives, right?
00:02:47.000But I think one of the things I learned is a deeper way of thinking about this, which is everyone listening to this, everyone watching this knows that they have natural physical needs, right?
00:02:56.000You need food, you need water, You need clean air, you need warmth.
00:03:00.000If I took those things away from you, you would be in real trouble real fast, right?
00:03:03.000There's equally strong evidence that human beings have natural psychological needs, right?
00:04:29.000And bear in mind, this thing that we don't like has spread over even more of our lives, right?
00:04:32.000Average person answers their first email at 7.48am and leaves work at 7.15pm.
00:04:38.000So this is most of our waking lives we're doing something we don't like.
00:04:41.000I start to think, could there be some connection between that and this epidemic of All sorts of forms of despair, anxiety, depression, addiction.
00:04:50.000So I started to look for scientists who'd studied this.
00:04:53.000I discovered an amazing Australian social scientist called Professor Michael Marmot, who I got to know, who discovered the key to what causes depression at work, right?
00:05:03.000I can tell you the story of how he discovered it, if you want, because I think it's an amazing story.
00:05:07.000But the core of it is, if you go to work, And you are controlled, so you feel you have low or no control, you are radically more likely to become depressed.
00:05:18.000You're even more likely to have a stress-related heart attack.
00:05:21.000And I think the reason is clear, although I'm a bit further than Professor Marmot does.
00:05:24.000Human beings need to feel our lives have meaning, right?
00:05:27.000And if you're controlled all the time, you don't feel like your life has meaning.
00:05:32.000It disrupts your ability to create meaning out of your work.
00:05:35.000And it makes you feel like shit, right?
00:05:39.000And one of the things that was really important to me in everything I was learning in the research for Lost Connections was, it required this kind of shift in my mind, because what I was basically told by my doctor is, your pain is a malfunction, right?
00:05:54.000He said, you know, we know what causes depression, it's just some people naturally have low levels of serotonin in their brains.
00:06:11.000There are real things that happen in your brain, obviously.
00:06:13.000But actually, Professor Andrew Scull at Princeton University says it's deeply misleading and unscientific to say depression is just caused by low serotonin, right?
00:06:22.000But one thing that was so important to me, looking at these nine real causes of depression and anxiety, was realising, actually, our pain makes sense, right?
00:06:31.000If you're depressed, if you're anxious, you've been told, basically, that you're a bit crazy, there's something not working.
00:06:37.000But actually, you're not a machine with broken parts, right?
00:06:40.000You're a human being with unmet needs.
00:06:43.000And that requires a very different set of responses.
00:06:45.000So you think about, I start to think, well...
00:06:47.000Let's think about that problem with work, right?
00:06:49.000Most people feel they've got no control at work or low control and it's making them feel terrible.
00:06:53.000They're not wrong to feel that, right?
00:06:55.000They've got a need as human beings and it's not being met.
00:06:59.000And I learned there's a really interesting strategy to deal with this.
00:07:03.000Now, this is something some people will be able to do as individuals, but it's something we can actually change as a society so far more people could do it.
00:07:09.000I went to Baltimore and I interviewed a woman called Meredith Keough, a young woman.
00:07:14.000Meredith used to go to bed every Sunday night, just fucking sick with anxiety, right?
00:08:41.000So they control their environment together.
00:08:43.000They're like a little tribe that control their environment instead of an army with one guy at the top controlling it.
00:08:49.000And one thing that was so fascinating spending time with them, which is totally in finding with Professor Michael Marmot's research about what causes depression at work, It's how many of them talked about having been really depressed and anxious when they were working in this controlled way.
00:09:03.000And their depression and anxiety had largely gone, still had bad days of course, but that kind of nagging depression and anxiety had gone away in this different environment.
00:09:10.000And as Josh said to me, There's no reason why any business should work in this top-down, controlled way that makes people depressed.
00:09:41.000But actually, once you begin to realize that the reasons why people are depressed and anxious make sense, this is just one of many reasons why people are depressed and anxious, and also one of the things that's fueling the addiction crisis, which you can talk about if you want.
00:09:53.000Once you realize it makes sense, you suddenly realize what you've got to do is deal with the problem in the world as well as the problem just in the individual's skull.
00:10:00.000Yeah, so you're focusing on work environments, right?
00:10:03.000And there's many reasons, as you were saying, for people being depressed.
00:10:08.000When you talk about work environments, have you researched people who are independent, people who work for themselves, people who make things or make furniture or what have you?
00:10:18.000Yeah, and that was one of the things as well at Baltimore Bicycle Excess.
00:10:20.000Most people are so removed from their work, right?
00:11:06.000And I remember him saying to me, look, I know people need paint, right?
00:11:09.000It's not, I know that I have some function here in the economy.
00:11:12.000Don't think you put it quite like that.
00:11:13.000But this is not giving me any sense of meaning.
00:11:15.000But one of the real mysteries to me about Joe, and for that I had to learn about one of the other causes of depression and anxiety, and solutions to that, was...
00:11:23.000So Joe, a lot of people, some of my relatives who do work like that, They're basically, the margin for them to change their lives is really narrow, right?
00:11:32.000Like one of my closest relatives is a struggling single mom.
00:11:36.000You know, she works every hour she can, she gets home at the end of the day, collapses, right?
00:11:40.000The idea of saying to her, your job now is to democratise your workplace is ridiculous, right?
00:12:16.000And he said, you know, when I was in Florida...
00:12:19.000I realised I could just quit this job.
00:12:21.000I could go and live as a fisherman in Florida.
00:12:23.000I'd make less money, but I'd be much happier, right?
00:12:27.000And somehow I knew as I was talking to Joe, and I followed up with him over the years that followed, I knew he wasn't going to go to Florida, right?
00:12:35.000It's just the way he said it, it was a wistful longing, not a...
00:12:38.000A whimsical idea, not something based on a real possibility.
00:12:42.000That's a really good way of putting it, but I remember the last time I saw him, and he walked off, and I felt like a complete dick for doing this, but I shouted after him because I felt it so strongly.
00:13:07.000But if you think about an individual like Joe, what's going on there?
00:13:09.000And one of the things I learned from this amazing Professor Tim Kasser in Illinois, at Knox College in Illinois, is I think one of the things...
00:13:16.000This is one of the hardest causes of depression to learn about, because I realised how much it played out in my own life as well.
00:13:24.000Just like we all know, junk food has taken over our diets and made us physically sick, right?
00:13:29.000Something similar has happened with our minds.
00:13:31.000The kind of junk values have taken over our minds.
00:13:33.000When I started learning about this, I kept remembering.
00:13:35.000So I ate nothing but junk food for like 10 years from my 20s, basically.
00:13:39.000And I remember one day, it makes this story even sadder that it was Christmas Eve in 2009. At lunchtime, I went to my local KFC and I said my order, which I won't even repeat to you because it was so disgusting.
00:13:51.000And the guy behind the counter said, oh, Johan, we're so glad you're here.
00:13:56.000And he said, wait a minute, wait a minute.
00:13:58.000And he went back and he came out and the whole staff had bought a fucking massive Christmas card for me and they'd written in it, to our best customer.
00:14:06.000And my heart, it's like sang because I was looking at this and I suddenly realised this wasn't even the fried chicken shop I went to the most, right?
00:14:13.000So I was at an extreme end of the junk food spectrum, right?
00:14:16.000I'm not anymore, though I've relapsed a bit lately.
00:14:31.000And what Professor Kasser found is that there's similar things happen in our minds.
00:14:36.000Weirdly, so for thousands of years, philosophers have said, if you think life is about, you know, money and status and showing off, you're going to feel like shit, right?
00:14:45.000But it's not an exact quote from Confucius, but that's the gist of what he said, right?
00:14:49.000But weirdly, no one had actually scientifically investigated this until Professor Kasser 25 years ago.
00:14:56.000So he knew that basically, to put it crudely, there's two kinds of motives that human beings have, right?
00:15:54.000The more you are driven by extrinsic values, the more your life is guided by how you look to the outside, by, you know, what you're trying to get out of life rather than enjoying it, the more you will become depressed and anxious by quite a large margin.
00:16:08.000There's loads of studies that show this.
00:16:11.000And also he found that we have become much more obsessed with, much more driven by these values over the last 30 years for all sorts of reasons, partly because From the minute we're born, we're immersed in a machine that tells us life is about consumption, right?
00:16:49.000It wouldn't make you want to buy anything.
00:16:50.000So, this movement towards these kind of junk values, and he shows lots of reasons why these junk values make us feel like shit.
00:16:59.000One is, it just corrodes the quality of your relationships, right?
00:17:03.000If your wife, if you think your wife loves you, not because you're you, but because you're rich, because you look good or for some other reason, then think about the insecurity that enters into that relationship.
00:17:14.000You know, oh right, if you suddenly got fat or if you suddenly lost all your money, it's over.
00:17:18.000It creates that sand of insecurity enters all your relationships.
00:17:23.000The more you're extrinsically motivated, the more insecure your relationships will be and the worse you'll feel.
00:17:37.000For you, I'm sure it's partly broadcasting, partly working out.
00:17:39.000As you can see, it's not working out for me.
00:17:42.000Where you just get into the zone and time seems to collapse and you're in that moment, right?
00:17:48.000But what thinking extrinsically, what being dominated by these junk values does, is it jolts you out of the intrinsic value.
00:17:55.000So imagine, go back to the piano example.
00:17:57.000If you're playing the piano just because you love it, and then suddenly you think, am I the best piano player in Los Angeles today, right?
00:18:04.000How are these people in this room thinking about my piano playing?
00:18:07.000How much am I going to be paid for this piano playing?
00:18:09.000You can see how that would jolt you out of the flow state, right?
00:18:12.000People who, the more we're driven by extrinsic values, the less we get into flow states and the worse we feel.
00:18:16.000There's lots of other reasons as well I can talk about.
00:18:18.000Well that completely makes sense, that relying constantly on other people's approval and recognition and love in order for you to be satisfied and happy is not a good recipe for getting by in this life smoothly.
00:18:33.000When you were young and you were experiencing depression, as you called it, what was the root cause of it?
00:18:38.000So in my case it was, I mean there were a few things going on, and this is quite difficult for me to talk about, but One of the people I got to know for Lost Connections is this amazing guy called Dr. Vincent Felitti in San Diego.
00:18:51.000And if you don't mind, I'll tell you his story first.
00:18:53.000I'll tell you what it made me realize about myself and actually why I was very resistant to this.
00:19:27.000Growing problem with obesity and they were trying everything and nothing was worth, like giving people nutritional advice, that stage wasn't working, right?
00:19:35.000So they basically said to him, they gave him quite a big budget and they're like, just figure out what the hell is going on here.
00:19:40.000So he went away and he started to work with, I think it was about 350 extremely obese people, right?
00:19:47.000People who weighed more than 400 pounds.
00:19:49.000And he starts doing all sorts of different research with them.
00:19:52.000And one day he just had this kind of almost stupidly simple thought.
00:19:56.000He thought, what if they just literally stopped eating and we gave them the nutrients they need?
00:20:03.000Would they just lose loads of weight and then come down to a healthy weight?
00:20:06.000So they obviously would like massive medical supervision.
00:21:00.000He's like, when was it you started to put on weight?
00:21:02.000For her, it was when she was 11. And so he's like, well, what happened when you were 11 that didn't happen when you were 10, that didn't happen when you were 12 or 15?
00:21:10.000And she said, oh, well, that's when my grandfather started raping me.
00:21:16.000So he starts talking to the group and he discovered 55% of the extremely overweight people in the group, 50% of people in the group, had put on their weight after being sexually abused, right?
00:21:27.000Which was an extraordinary, far more than the wider population.
00:21:30.000He's like, wait, what's going on here?
00:21:55.000So Vincent wanted to get a lot more research on this, and this is where it led to the breakthrough in depression.
00:21:58.000So he set it up with funding from the CDC, the Center for Disease Control, kind of gold-plated organization in this, in the US for this kind of research.
00:22:08.000Everyone who came to Kaiser Permanente in the next, I think it was a year, For anything, whether you broke your leg, you had migraines, you had schizophrenia, anything, got given a questionnaire.
00:23:02.000There's a debate about why this is, and I'm going beyond what Vincent says now, beyond what the science says, and this brings it back to my experience.
00:23:12.000So I had, when I was a kid, I'd experienced some very extreme acts of violence from an adult in my family.
00:23:17.000You know, my mother had been very ill.
00:23:20.000When I was a kid, my dad was mostly in another country, and I'd experienced these really, really extreme and frightening acts of violence.
00:23:28.000And I... This sounds stupid, but until I went to see Vincent, if you had asked me, do you think that played a role in your depression, I would have said no, right?
00:23:39.000And it makes me realise, one of the reasons why I clung to this very simplistic chemical imbalance theory of depression for so long...
00:23:48.000Because I did not want to give the individual who behaved so appallingly towards me that sense of power over me.
00:23:55.000I didn't want to think about that stuff.
00:24:02.000I wanted to say, well, okay, that's a bad thing that happens to you.
00:24:05.000But the reason why I stayed with this and the reason why I spent this time with Vincent in San Diego and the reason why I kept going with all these different causes of depression and anxiety is because once you understand what's happened, you can find solutions you otherwise didn't find.
00:24:19.000So there was a second stage of Dr. Felitti's research that to me was so powerful.
00:24:24.000It's one of the reasons why I make myself talk about this now.
00:24:27.000So if you'd indicated on the form that you'd experienced one of these forms of childhood trauma, the next time you went back to your doctor, you weren't called back, But the next time you went to your doctor, your doctor was told to say something to you like, Hi Joe, I see on the form you indicated that you were violently abused when you were a child.
00:24:47.000I'm really sorry that happened to you.
00:25:21.000I think partly what happens is, it's related to shame, right?
00:25:25.000If you are a kid and you experience some kind of abuse, you can basically do one of two things, right?
00:25:31.000You can either say, look, I'm fucked here, right?
00:25:34.000I'm like a pinball being smacked around a pinball machine because I can't stop this happening and I've just got to accept it and I'm really vulnerable.
00:25:41.000Or you can say, This must be my fault at some level, right?
00:25:47.000Which is what I did, and of course it's what you're being told anyway by whoever's treating you badly in almost every case.
00:25:52.000And a weird thing is, if you tell yourself it's your fault, Actually, you gain a sort of weird internal power, right?
00:25:59.000You're not the pinball being smacked around the machine.
00:26:01.000You're the person controlling the pinball machine.
00:26:04.000You can't change the other person's behaviour.
00:26:06.000So you kind of develop this kind of shame.
00:26:09.000And one of the things we know is, and there's plenty of evidence from this, people like Professor Jim Pennebaker have shown it, Shame is a catastrophe for human psychology, right?
00:26:19.000We know, for example, openly gay men died two years later than closeted gay men in the AIDS crisis, even when they got medical care at the same time, right?
00:26:27.000Shame destroys you, it makes you sick.
00:26:29.000And what Vincent found was this model of releasing your shame, which led to this significant...
00:26:35.000I remember one of the letters he got was from an old woman, I think she was in her 80s, who'd been sexually abused when she was a kid.
00:27:20.000So there seems to be most scientists agree, not all of them, and there are some people who dissent from this, but most scientists agree low serotonin correlates with depression, right?
00:27:30.000In the same way, stretch marks correlate with obesity, but they're not the cause of obesity, they're the product of it.
00:27:35.000So there are real brain changes that happen, which I write about in Lost Connections, and important to say that, that I don't think they should be described as chemical imbalances.
00:27:42.000But one of the things that was really shocking to me was one of the British experts on this, Dr. David Healy, said to me, you can't even say the idea that depression causes serotonin, you can't even say that that theory is discredited, because it was never credited.
00:27:57.000There was never a time when half of the scientists in the field believed that, right?
00:28:01.000The reason that story got sold to me and most people listening to this in the 90s is because it worked really well for the drug companies, right?
00:28:08.000Because what it makes it sound like, if you've just got a chemical imbalance, the solution is just to give you chemicals.
00:28:12.000Now, it's important to say chemical antidepressants do play a role.
00:28:16.000And there's a slightly nuanced point to make about this, which is, so depression is measured by something called the Hamilton scale, right?
00:28:22.000I've always felt sorry for whoever Hamilton was, that the only way we remember him is by how fucking miserable we are.
00:28:27.000So the Hamilton scale goes from 1, where you are, you know, dancing around in ecstasy or on ecstasy, to 51, when you would be acutely suicidal, right?
00:28:36.000And to give you a sense of what movement on the Hamilton scale looks like, if you move six points on the Hamilton scale, sorry, if your sleep patterns get better, you'll gain six points on the Hamilton scale.
00:28:46.000And if your sleep patterns deteriorate, say you have a baby who's crying all the time, you'll generally lose six points on the Hamilton scale, right?
00:28:53.000So, Professor Irving Kirsch at Harvard Medical School did the best research on this, and what he found is, on average, chemical antidepressants move people 1.8 points on the Hamilton scale, right?
00:29:04.000About a third of what improving your sleep patterns does.
00:29:07.000It's important to say that's an average, so some people do get more than that, some people get less.
00:29:11.000And you can see 1.8 points It's not nothing, right?
00:29:14.000If you're acutely suicidal, 1.8 points can take the edge off.
00:29:17.000There's real value in giving people that relief.
00:29:19.000But it is not solving the problem for most people.
00:29:21.000I thought I was, you know, weird for being on antidepressants for so long and remaining depressed.
00:29:29.000According to Dr. Steve Allardy, who's a professor of psychology, who's done a lot of work on this, between 65 and 80% of people taking chemical antidepressants become depressed again.
00:29:38.000So you can see that's not 100%, there is some value.
00:29:42.000Well, isn't that what a bilify is for, right?
00:29:44.000A bilify is the idea that your antidepressant is not enough, so you take a bilify on top of your antidepressant, which is supposed to help you even further.
00:29:52.000And it's one of the most prescribed medications in the country, and it's an anti-psychotic, which is terrifying.
00:30:06.000A cultural madness that we're doing this right where the now this is not to say that I want to stress again There is a real value in these drugs.
00:30:13.000There is some value to them There's some value to them, but they're most certainly over prescribed and there's most certainly actual Methods that you could use to improve your life without any sort of chemical intervention that are readily available to everybody like exercise and diet and But those things aren't stressed when you go to a doctor.
00:30:34.000The first thing the doctor doesn't say is, listen, what we need to do is get you to start running and get you to start eating really healthy, and then let's talk about antidepressants.
00:30:49.000So this is why, although there is a real value for those drugs, why this is the first primary and for most people only option that's ever offered.
00:30:57.000And one of the things that really helped me change, think about this differently, and it fits exactly what you're saying, Joe, is I went to interview this South African psychiatrist called Derek Summerfield.
00:31:06.000And Derek happened to be in Cambodia when chemical antidepressants were first introduced, right?
00:31:33.000There was a farmer in their community who one day, he worked in the rice fields, who one day had stood on a landmine and got his leg blown off.
00:31:40.000So they gave him an artificial limb and he went back to work in the rice fields.
00:31:43.000But apparently it's super painful to work in water when your leg's been, you know, when you've got an artificial limb and your leg's been blown off.
00:31:49.000And I'm guessing it's pretty traumatic because he's in the fields where he's been blown up.
00:31:53.000He starts to cry all day, doesn't want to get out of bed.
00:32:22.000Now, if you've been raised to think about depression the way we have, we've been propagandized to, that sounds like a bad joke, right?
00:32:28.000I went to my doctor for an antidepressant and he gave me a cow.
00:32:31.000If you understand what all these experts who I met have been, and interviewed extensively, have been trying to tell us, if you understand what the World Health Organization has been trying to tell us, those Cambodian doctors knew intuitively what they knew through the science, which is our pain makes sense, right?
00:32:53.000Some of them are these bigger interventions.
00:32:55.000So one of the heroes of Lost Connections is this doctor I got to know called Sam Everington, who is based in East London, actually near where I lived for a long time.
00:33:04.000Very poor part of East London, and sadly he was never my doctor.
00:33:08.000But Sam was really uncomfortable because he's a general practitioner, he's a general doctor.
00:33:12.000Loads of people were coming to him with depression and anxiety, right?
00:33:15.000And he'd been told in his medical training, even though he knew the science was much more complicated than this, to just say to people, you know, you've just got a chemical imbalance in your brain and just drug them, right?
00:33:26.000And Sam thought, like me, he's not opposed to the drugs, he does give them out to some people, but he just thought...
00:33:38.000He noticed that one of the factors that was making them depressed and anxious was how profoundly lonely they were.
00:33:43.000It's a study that asks, obviously this is in Britain, but figures are similar to Britain by giving American examples, a study that asks Americans, how many close friends do you have who you could call on in a crisis?
00:33:53.000When they started doing the study years ago, the most common answer was five.
00:33:57.000Today, the most common answer is none.
00:34:15.000The reason why you and I are sitting here, Joe, in LA, the reason why we're alive is because our ancestors in Africa On the savannahs of Africa were unbelievably good at one thing, right?
00:34:25.000They weren't bigger than the animals they took down, but they were much better at cooperating than the animals they took down.
00:34:30.000We exist because our ancestors formed into tribes.
00:34:34.000Every instinct we have is to live in a tribe, right?
00:34:37.000Bees need a hive, humans need a tribe.
00:34:39.000We are the first humans ever to try to disband our tribes, right?
00:34:42.000No one's ever done that before in human history.
00:34:59.000Remind me to come back to the thing about East London.
00:35:01.000I know this is an issue with a lot of people.
00:35:03.000I know people that worship at the altar of science and modern medicine that firmly believe that all depression is because of some sort of chemical imbalance in the brain and anything that debates that or anything that disputes that notion pisses them off.
00:35:46.000You won't get many scientists who say, in fact, you struggle to find any scientists who say depression is purely a biological phenomenon, right?
00:35:54.000Pretty much everyone agrees there's some social and psychological component.
00:35:58.000It's a weird disconnect between what the scientists know and what the public is told, right?
00:36:02.000I don't know anyone who went to their doctor who, apart from this wonderful doctor in East London who we can talk about, Who went with depression and anxiety and was told anything other than a biological story.
00:36:14.000I mean, they may be asked, you know, some of them were asked about childhood, you know, what was your childhood like and referred to a therapist.
00:36:18.000But no one was told about these wider social causes.
00:36:21.000No one was told, like, do you feel controlled at work?
00:36:36.000And I think there's two things to say about that.
00:36:38.000One is, I started to, for various reasons, for research, for something else, I was reading some, like, feminist texts from the early 60s, right?
00:36:47.000And a really common thing that happened in the early 60s is women would go to their doctor and they'd say, Doctor, there's something really wrong with my nerves.
00:36:54.000People talked about it in terms of nerves then, we don't do that anymore.
00:36:57.000There's something really wrong with my nerves because I've got everything a woman could possibly want.
00:37:01.000I've got a husband who doesn't beat me, I've got a car, I've got a washing machine, I've got two kids, but I feel like shit, right?
00:37:07.000And the doctor would go, you're right, and give her Valiant.
00:37:09.000Now, if we could travel back in time and speak to those women, what we'd say is, right, you've got everything you could possibly want by the standards of the culture, But standards of the culture are just wrong, right?
00:37:19.000As a woman, as a human being, you need more than just a washing machine and a car, right?
00:37:24.000You need a fulfilling life, you need to have meaning and purpose.
00:37:27.000And a very similar thing I think is happening today.
00:37:29.000So for example, when I speak to people who say, I've got everything I could want, but I feel like shit.
00:37:35.000Very often they're working really hard in prestigious jobs, That they don't like, they don't enjoy hour by hour, to buy things that don't give them pleasure.
00:37:44.000It comes back to this hijacking by junk values that we're talking about that Professor Tim Kasser discovered.
00:37:48.000So what you've got is, because we've been told a totally misleading story about what makes us satisfied and happy as human beings, I think this comes up again and again in the interviews you do.
00:37:58.000Because we've been taught in different ways, because we've been told a misleading story about that, we live our lives according to the wrong script.
00:38:04.000We feel like shit, and rather than question the script, we think there must be something wrong with us biologically.
00:38:09.000Now, there are biological contributions, it's important to say that, but one of the things that really blew my mind on this was...
00:38:14.000I interviewed this amazing social scientist called Dr. Brett Ford in Berkeley.
00:38:19.000She did this research, it's kind of simple research.
00:38:25.000If you consciously decided you were going to spend more hours a day trying to make yourself happier, would you actually become happier, right?
00:38:33.000And they did this research, she didn't do it alone obviously with her colleagues, in the United States, Japan, Russia and Taiwan.
00:38:42.000And what they found was, in the US, if you try to make yourself happier consciously, you do not become happier.
00:38:49.000In the other countries, if you try to make yourself happier, you do become happier.
00:38:56.000So they did more research, and what they discovered was, in the US, and obviously I spend a lot of my time here, but in Britain as well, if you try to make yourself happier, You try to do something generally for yourself.
00:39:48.000So your intrinsic value could be spending time with your kids, right?
00:39:51.000That was probably most people's strongest intrinsic value, if they're parents, is being with their kids, bonding with their kids, loving their kids.
00:39:57.000But my point is, if your goal is to get happy, and the way you've chosen to get happy is, I'm going to get happy by making other people happy.
00:40:26.000When they were told, make yourself happy, they had an implicit script in their culture, which was like, oh right, if I want to make myself happy, I'll spend time with other people, I'll do things with other people.
00:40:35.000But if you think about it in terms of human evolution, it makes total sense, right?
00:40:38.000Think about our ancestors, where they evolved, If our ancestors had been individualists who were out to big up themselves as individuals, we wouldn't be having this conversation, right?
00:40:50.000So it makes sense that we evolved as a species with instincts that are...
00:41:12.000But this script that we have, this idea that the way you make yourself happier is as an individual, you know, just doing something for yourself.
00:41:21.000Let's stop there, because there is not one script in this country of how to make yourself happy.
00:41:25.000I think that's sort of disingenuous, this idea that the only way to make yourself happy is to do that.
00:41:31.000That's not what people are trying to do.
00:41:33.000What people are trying to do is be successful.
00:41:36.000And I don't think they necessarily equate success with happiness, but what they do equate success with is an alleviation of debt, an alleviation of problems, an alleviation of a lot of the issues that people face.
00:41:48.000And they think of that as, if you look at the problems that you have when you're growing up, especially if you grow up in a poor family, one of the main problems that you face is you're worried about paying your bills.
00:41:59.000So you say, someday I'm going to get to a point where that is no longer an issue.
00:42:06.000They're not doing it thinking this is going to make me happy.
00:42:10.000I very rarely see that, which is one of the reasons why people, even people's parents, and this freaks me the fuck out, will tell them to not pursue their dreams, but instead to pursue something that's more likely to happen.
00:42:24.000Like, don't pursue your dream of becoming an actor or a singer or whatever it is.
00:42:29.000Instead, pursue your dream of being the foreman at the company you work at because that's attainable.
00:42:35.000I think you're totally right, and I think there's a lot of evidence that you're right, that the financial anxiety is a massive driver of depression and anxiety, obviously.
00:42:44.000There's an interesting study that found people who have an income from property are ten times less likely to develop an anxiety disorder than people who don't.
00:42:52.000And there was a really interesting experiment in how we can respond to that.
00:42:55.000It's one that President Obama said late in his term he thinks would have to happen across the country in the next 20 years for various reasons.
00:43:01.000So in Canada in the 70s, the Canadian government chose a town at random.
00:43:07.000It seems to genuinely have been random.
00:43:10.000Anyone who knows Canada, it's about four hours out of Winnipeg.
00:43:13.000And they said to a big group of people in this town, We're going to give you guys, for the foreseeable future, we're going to give all of you a guaranteed basic income.
00:43:23.000We're going to give you the equivalent of, in today's money, $15,000, right?
00:43:27.000There's nothing you can do that means we'll take it away from you, and there's nothing you have to do in return for it.
00:43:33.000We want you to have a good life, right?
00:43:34.000It was partly because they had a kind of welfare system, but a lot of people were falling through the cracks, and they wanted to do a little experiment to see if this worked better.
00:43:41.000And this was studied very carefully by a woman I interviewed called Dr. Evelyn Forgey.
00:44:37.000Financial anxiety is a massive driver of the despair.
00:44:42.000I mean, more than half of all Americans have not, because of the incredible financial pressure they've been put under, Do doctors still say that?
00:45:05.000My nephew's best friend just literally a couple of weeks ago went to the doctor and was told, yeah, you've got a dopamine imbalance.
00:45:11.000The doctor said it's migrating Was this in England or in the United States?
00:45:15.000This was in England, but I get contacted constantly by people who are being told they've got chemical imbalances in their brains.
00:45:20.000Are they just as likely to prescribe antidepressants in England as they are American?
00:45:25.000It's slightly lower, but it's still exceptionally high.
00:45:29.000There's that narrative that an antidepressant must be in some sort of a pill form.
00:45:34.000And even the expression antidepressant, an antidepressant, it's a very confusing thing that we've sort of adopted very quickly in this country.
00:45:43.000And it's relatively recent, you know, over the last 60, 70 years.
00:45:48.000And the people that have antidepressants in their body, that take them all the time and swear by them, Boy, if you try to tell them in any way that there's a better option, they get extremely defensive.
00:46:02.000I have a friend, she's very smart, and she's one of the people that will Very aggressively debate this idea that it's anything but a chemical imbalance.
00:46:19.000But she doesn't take care of her body.
00:46:34.000And so a big thing for me is, when I'm talking to this, because I've had some of that reaction as well, not too much, but I've had some of that reaction as well.
00:46:41.000First thing for me, I always say is, I want to expand the menu of options.
00:46:44.000I don't want to take anything off the table, right?
00:47:06.000Obesity has massively risen in the Western world.
00:47:08.000It hasn't risen because people suddenly became greedy and lazy.
00:47:11.000It's risen because our food system is terrible, the food supply system is terrible, and we've built cities that people can't walk and bicycle around, right?
00:47:17.000And they're really stressed all the time, and they get home from work exhausted, so they don't have time to exercise, a lot of them.
00:47:22.000In that context, some people will do stomach stapling, liposuction, that kind of thing, right?
00:47:28.000I'm not against that, but if we change the society in the way that I would want to with obesity so that people could walk and cycle and, you know, they had access to healthy food, far fewer people would need stomach stapling or liposuction, right?
00:47:41.000So I would draw, it's not a perfect analogy, but I'd say, if the social changes that I want to happen, happen, if we follow the places that have succeeded in reducing depression and anxiety, Over time, you would see fewer people feeling they needed chemical antidepressants.
00:47:54.000I would stop you with a couple of things.
00:47:57.000First of all, I don't think it's access to healthy food.
00:47:59.000I think most people have access to healthy food.
00:48:32.000One of my relatives who's very overweight, you know, she's constantly fucking stressed because she's trying to hold together so much and one of the few reliefs and pleasures she has is to eat too much, right?
00:48:55.000I mean, I think of this in relation to addiction and you tweeted once a TED talk I gave, everything you think you know about Addiction is wrong, which I'm grateful, thank you, which is partly taken from my previous book, Chasing the Scream, which is about addiction, and I think about what you're saying in relation to that context.
00:49:09.000So, we had a lot of addiction in my family, and, you know, one of the things that really changed my mind about this, and I think it really relates to what you're saying about food, is most people think, you know, addiction, I say drug addiction, I say heroin addiction, right, which is something very close to me.
00:49:25.000Most people think heroin addiction, if you said what causes heroin addiction, they'd say, Dar, heroin causes heroin addiction, right?
00:49:31.000We've been told this story for a really long time that, you know, if we kidnapped someone off the street, we injected them with heroin every day for 20 days, at the end of that they'd have this desperate physical hunger for the chemical hooks in heroin, their body would desperately need it,
00:49:47.000and that's why they would be addicted, right?
00:49:50.000The first thing that alerted me about something not right about that is when it was explained to me in Britain, If you get hit by a truck and, you know, you break your hip and you're taken to hospital, you'll be given loads of a drug called diamorphine, right, for the pain.
00:50:04.000It's much better than street heroin because it's medically pure, right?
00:50:07.000If anyone listening to this has a British grandmother who had a hip replacement operation, your grandmother's taken a lot of heroin, right?
00:50:13.000If what we've been told about the chemical hooks is right, what should be happening to all these people in hospital?
00:50:18.000Loads of them should be becoming addicted.
00:50:20.000It doesn't happen in Britain with people who are given diamorphine.
00:50:24.000I only began to understand it when I went to Vancouver and interviewed this incredible professor there called Bruce Alexander who did this experiment.
00:50:31.000It's changed how we think about addiction and I think it's very relevant to what you're saying about food.
00:50:34.000So this theory, the chemical hooks theory of addiction, and chemical hooks are real, they're just a small part of it.
00:50:39.000The chemical hooks theory of addiction comes from a series of experiments that were done years ago They're really simple.
00:50:45.000You take a rat, you put it in a cage, and you give it two water bottles.
00:50:49.000One is just water, the other is water laced with either heroin or cocaine.
00:50:53.000If you do that, the rat will almost always prefer the drugged water and almost always die quite quickly, right, within, I think, is a week.
00:51:21.000They've got grain they like and coloured balls.
00:51:24.000And they've got both the water bottles, the normal water and the drugged water.
00:51:27.000But the fascinating thing is in Rat Park, they don't like the drugged water that much.
00:51:31.000None of them used it, they do use it, but none of them used it compulsively and none of them ever overdosed.
00:51:36.000So when they're deprived of the things that make life meaningful, they turn obsessively to the drug.
00:51:40.000When they've got the things that make life meaningful for rats, they don't.
00:51:42.000The opposite of addiction isn't sobriety, the opposite of addiction is connection.
00:51:46.000I think you can see a similar principle playing out with food, right?
00:51:48.000Of course there's some margin to the individual, I don't want to say that we're not entirely the product of our environment.
00:51:53.000Very far away from this woman, these people that were on this diamorphine.
00:51:58.000So why are you saying that they don't get addicted to it?
00:52:01.000Because they go back to their lives that are meaningful.
00:52:02.000There's a human example that happened at the same time as Rat Park, right?
00:52:05.000Why are their lives particularly meaningful in relationship to the lives we're talking about here?
00:52:10.000So I think you can see in an example, a good example that was happening at the same time as Rat Park, an experiment at the Vietnam War, right?
00:52:17.000Huge numbers of American troops in Vietnam, about 40% used heroin, right?
00:52:22.000And if you look at the reports from the time, they were shitting themselves because they were like, my God, when the war ends, we're going to have all these heroin addicts on the streets of the United States.
00:52:30.000They're going to come home because they believe the chemical hooks theory.
00:52:33.000It's a really good study in the Archives of General Psychiatry by Professor Lee Robbins that followed these guys home, a select group of them.
00:52:39.000And what it found was 95% of them just stopped, right?
00:52:44.000Didn't go into some catastrophic withdrawal.
00:52:47.000Some of them did experience some physical discomfort, but they didn't, you know, they didn't...
00:52:51.000Now, if you believe the old theory of addiction that you're taken over by the chemical hooks, that makes no sense, right?
00:52:56.000But they've been exposed to all the same chemical hooks as any homeless street addicted person living on the streets.
00:53:03.000But if you understand this different way of thinking, it makes perfect sense.
00:53:06.000If you took you and me now, and put us in a hellish, pestilential jungle, where we don't want to be, we could die at any moment, we'd be made to kill people, you would definitely survive longer than me, but we would both find heroin a lot more appealing than we do now, right?
00:53:18.000And then when we come back to our lives when we have meaning and purpose, We would find heroin a lot less appealing.
00:53:24.000The core of addiction is not wanting to be present in your life, because your life is too painful a place to be.
00:53:29.000So when an intervention happens that reduces the amount of pain in your life, you're going to be less addicted.
00:53:34.000There's a very challenging line, Marianne Faithfull, you know, the British Rocks.
00:53:37.000I'm going to stop you right there, because there is a giant issue, though, with people taking pain pills after operations that weren't on pain pills before, and then they get addicted to them.
00:53:47.000So do you think that's because of lack of meaning in their life, or is it because there is an absolute real chemical hook?
00:53:53.000Like, I have a good friend who had his nose broken, and they fixed his nose, and he got on some, I think it was Oxycontin afterwards, they prescribed it to him, and then four months later, he's taking it every day, all day.
00:54:04.000So there's a few things to say about that.
00:54:06.000Firstly, chemical hooks are real, but they're a small part of the picture.
00:54:08.000We know how much they are, so there's experiments that measure this.
00:54:12.000So lots of people will have taken, in fact, some people listening to this will be taking part in this experiment now, When nicotine patches were invented in the late 80s and they become marketed in the early 90s, there's this huge wave of optimism, right?
00:54:24.000Because the chemical hook in cigarettes is nicotine, right?
00:54:27.000Nicotine patches give you the chemical hook you're addicted to.
00:54:30.000And so there was this huge wave, they're like, oh great, we're going to give people the chem, because addiction is caused by chemical hooks, we're going to give them the chemical hook, they'll stop wanting these filthy smoke.
00:54:42.000In fact, what happened is 17% of people, according to the US Surgeon General's report, when they use nicotine patches and they're motivated to stop smoking, right?
00:54:51.000Really important to say, 17% is not no one.
00:54:54.000Big number that has saved hundreds of thousands of people's lives at a conservative estimate.
00:54:58.000But it still leaves 83% where something else is going on, right?
00:55:01.000But isn't that because of the delivery method?
00:55:03.000The delivery method of cigarettes is incredibly satisfying.
00:55:05.000You take a hit, you get it right into your system, and boom, you get that nicotine.
00:55:09.000The patch is transdermal, it's very slow, it's not the same feeling.
00:55:14.000Yeah, there are experiments that show there is pleasure that comes from the delivery method, but it's also about self-soothing, it's about anxiety, it's about boredom.
00:55:21.000And this is very important to relate to the opioid crisis.
00:55:24.000So one in 130 opioid prescriptions result in an addiction, right?
00:55:29.000So it's a small number, but a catastrophic and devastating number, and I've reported from the places that have been most affected by this, like Keene in New Hampshire.
00:55:49.000And that's in the United States or in the UK? Yeah, in the United States.
00:55:52.000That's one in 130 prescriptions, but bear in mind, some people get more.
00:55:59.000But one of the things that's really important to understand about that is the context in which this is happening, right?
00:56:05.000In Britain in the 80s, and this totally relates to what I write about in Lost Connections about depression as well as in Chasing the Scream about addiction.
00:56:12.000In Britain in the 18th century, there was this thing that happened called the gin craze, right?
00:56:17.000So huge numbers of people are driven out of the countryside into these disgusting urban slums where, you know, they're living in this awful...
00:56:25.000they've lost everything that made life meaningful to them, right?
00:56:28.000And what happened was an outbreak of mass alcoholism.
00:57:45.000I think part of the problem is because we've got such stigma about depression, anxiety, addiction, people will latch onto the biological explanation, whether it's the chemical imbalance theory, the chemical hooks theory, As their path out of stigma, whereas to me, you shouldn't be stigmatised in any fucking circumstance,
00:58:01.000whether it's because you're in pain, psychological pain, physical pain.
00:58:06.000I think one of the reasons why we're so committed to these, and it's not even a good way out of stigma, I can explain to you how, if you want this for interesting evidence about that, but do you see the point I'm making, Joe?
00:58:14.000I do see the point that you're making that people with lives that are unsatisfying or unfulfilling or there's some sort of a major issue in there like the athlete that's no longer going to be able to be an athlete, that that's going to make these drugs more enticing.
00:58:29.000But I know too many people that have had, like, real issues getting off of them.
00:58:38.000And most people, I mean, you're talking about the same people that have a hard time not eating shitty food, right?
00:58:44.000People that have a hard time getting disciplined enough to go to the gym.
00:58:49.000These are the same kind of people we're talking about.
00:58:51.000They're going to have a massive problem if you give them pills and those pills create a chemical hook, even if it's a chemical hook that you or I or a disciplined person would be able to get, like Dr. Carl Hart famously called it, he said, it's like getting over the flu.
00:59:07.000Everyone wants to pretend that you're gonna die.
00:59:09.000He goes, no, you feel like shit for a little while, and then you're fine.
00:59:11.000He goes, it's not the thing that everybody makes it out to be.
00:59:14.000Withdrawals are not the thing that everybody makes it out to be.
00:59:16.000But if you have the average person, and you give them pills, and those pills can keep them from getting the flu, they're gonna keep taking those pills.
00:59:25.000And if they stop taking those pills, they get the flu.
00:59:31.000I think there's some truth in what you're saying.
00:59:33.000So I think the key thing that happens, so I think Dr. Hart, who's a friend of mine, is totally right, but the physical withdrawal is, you know, a flu is not a nice thing, but it's not the most onerous thing in the world.
00:59:44.000But the thing that's really devastating is the resumption of the psychological pain that you were anaesthetising with the drug, right?
00:59:52.000If you want to understand why people are taking so many painkillers, we've got to understand why they're in so much pain.
00:59:56.000And that comes back to the nine causes of depression and anxiety that I write about in Lost Connections, and then the kind of seven solutions to this problem that I offer.
01:00:07.000Joe in the paint store, who I was talking about, who's, you know, who has this job he can't bear, has very little meaning in his life, feels his life is just slipping through his fingers.
01:00:19.000He actually contacted me because of my book.
01:00:22.000And my TED talk, and he thought he was telling me a story about addiction, right?
01:00:26.000But the truth is, when he took Oxy, he was numbed.
01:00:29.000It made him as numb as the work itself.
01:00:31.000And then when he stopped, he was acutely depressed and felt like shit.
01:00:34.000So I think the challenge is, if you are coming off of this drug into a society of profoundly lonely and isolated people who are financially insecure, Who've been told that life is about money and status, who think life is about screaming at each other through screens,
01:00:51.000a lot of those people are going to feel like shit.
01:00:53.000And it's not because they're individually weak, right?
01:00:56.000Maybe individual weaknesses, of course, we all have flaws.
01:01:14.000There are things individuals can do, obviously, and I talk about them a lot in Lost Connections.
01:01:18.000But I think the fact that it's a social transformation does tell you something.
01:01:23.000There's a good illustration of this, a kind of weird thing that was discovered about depression in the 70s.
01:01:28.000That was so inconvenient that psychiatrists tried to brush it under the carpet.
01:01:32.000So in the 70s, the American Psychiatric Association, for the first time, wanted to standardize how depression is diagnosed across the US. Because up to then, doctors were just using their own judgment about what it even was, right?
01:01:43.000So they drew up a list of 10 symptoms, kind of obvious things like feeling worthless, crying a lot, you know, you could guess what they were.
01:01:51.000And they send this out to doctors all over the US, and they use it.
01:01:56.000But within a couple of months, doctors start to come back and go, look, we've got a real problem here.
01:02:02.000Because if we just use this checklist, we should be diagnosing every grieving person as mentally ill, because these are the symptoms of grief, right?
01:02:09.000Everyone, when you lose someone, wants to cry a lot, has persistent feelings of sadness, that kind of thing.
01:02:17.000So the psychiatrists regrouped and they were like, okay, we'll create something.
01:02:21.000It was called the grief exception, which basically said, use this checklist to diagnose depression unless the person has lost someone they love in the last year, in which case none of this counts.
01:02:31.000But over the next few years that followed, there's this really awkward debate because they're like, wait a minute, we're being told to tell our patients that depression is just a brain disease that you can just identify from a checklist.
01:02:42.000Unless there's one situation in life where it's perfectly legitimate to react this way, but if that begs the question...
01:02:48.000What about all the other different things in your life?
01:03:07.000That seems to be one of the primary reasons why people today, I mean if you stop and ask the average person today who's not feeling well, I guarantee you they're going to be able to come up with at least one or two of those things on the list.
01:03:27.000Whether it's a job, financial stress, relationship stress, loneliness, friendship issues, or death in the family, or losing someone they love.
01:03:36.000But the fact that losing someone they love, like, we'll count that.
01:03:40.000That's the one thing we'll count, right?
01:03:44.000And the woman who did the most research on this, one of the best people I got to know for Lost Connections, a woman called Dr. Joanne Cassiotores, an amazing person.
01:03:56.000And she said, you know, she talks about the craziness of this.
01:03:58.000It just shows we don't understand pain in this society.
01:04:01.000She put it to me, grief isn't a pathology, right?
01:04:06.000She's done this research that shows, I think the figure is, 32% of grieving parents are diagnosed and drugged in the first 48 hours after their child dies.
01:04:14.000And she said, this is a sickness, right?
01:04:23.000It's a sign that you loved the person.
01:04:25.000And in a way, I'm going beyond what she says now, but, you know, I think one of the things, the fact that depression and grief have the same symptoms is really significant.
01:04:33.000Because I think depression is grief for your own life not going how it should, right?
01:04:38.000It's grief for your own needs not being met.
01:04:41.000Now when someone we love dies, all we can do is hold the survivors and love them, right?
01:04:51.000I mean, a really interesting example of something you've covered brilliantly on the show, Joe, about psychedelics, some of the research around psychedelics, which taught me a lot about how we might think about this differently.
01:04:58.000So, as you know, you know better than anyone.
01:05:01.000Until the mid-60s, loads of research was done giving LSD to...
01:05:06.000People with depression, alcoholism, various problems.
01:05:08.000They weren't done to the standards we want to do scientific experiments now, but they found really promising results, and then Nixon shuts the whole thing down, right?
01:05:15.000In the last six years, there's been a huge reawakening of this.
01:05:18.000I went and interviewed for Lost Connections, the teams that have worked on this, in Here in LA, at UCLA, at NYU, at Johns Hopkins in Baltimore, in London at UCL, in Sao Paulo, and in Norway.
01:05:32.000I'm a fan about this, but there's one that I think really relates to our conversation powerfully.
01:05:36.000Well, loads of things, but I'll talk about one.
01:05:39.000So there was a sub-finding of one of the studies that I became obsessed with.
01:05:44.000They did this research at Johns Hopkins in Baltimore, some of the leading scientists in the world, where they gave psilocybin, the active component in magic mushrooms, To chronic long-term smokers who tried everything to stop smoking and had not succeeded.
01:05:59.000I thought about my mother a lot because my mother is a chain smoker.
01:06:02.000There's a photograph of me and her when I'm six months old.
01:06:05.000She's breastfeeding me, smoking and resting the ashtray on my stomach.
01:06:45.000So they did all this research in this.
01:06:47.000And what we've got to be careful with psychedelics is to not talk about it the way we were misleadingly told about antidepressants, chemical antidepressants in the 90s, which is, oh, it flips a chemical switch in your brain.
01:06:57.000Clearly, a chemical process happens in the brain.
01:06:58.000But what they found, I think the most important thing, and a lesson for people who don't want to use psychedelics as well, is...
01:07:06.000So, if you take psilocybin, most people will have a kind of spiritual experience, right?
01:07:14.000Some people will have a super intense spiritual experience, some people have a mild one, and a minority will have no spiritual experience.
01:07:20.000It turns out the positive effects, like a reduction in depression, addiction, correlate exactly With the intensity of the spiritual experience.
01:07:28.000So if you have no spiritual experience, you don't have...
01:07:47.000Most people have much more intense experience with the strongest dose.
01:07:51.000But the key thing, I think, about that finding is Is that, as one of the experts put it to me, it's not that it's a chemical process, it's a learning experience.
01:08:01.000What it does is it gives you an experience of what it can feel like to be deeply connected, to feel deeply connected to the people around you, to the natural world, incredible, strong natural antidepressant that we can talk about if you want.
01:08:14.000When I was a teenager, I bought some and I think they were a drug dealer in Camden Town Market.
01:08:19.000I'm holding off because I've got to go to the Amazon rainforest later this year and I want to use ayahuasca for the first time in the Amazon.
01:09:23.000You can either start fresh and try to re-examine the world with fresh eyes, or What's more convenient is you slowly slip into the my old bullshit folder and start opening it up and repeating patterns and lighting that cigarette up when you really shouldn't, having that drink when you probably shouldn't do that either.
01:09:39.000And those things are common because it's comforting.
01:09:43.000It's comforting for people to repeat patterns that they're familiar with.
01:09:47.000You're totally right and the scientific evidence is overwhelming.
01:09:49.000In fact, at UCL, at the University College London, Professor David Nutt did all this research that shows One of the things that happens in your brain when you take psychedelics is the part of the brain that relates to ego just doesn't function, right?
01:10:01.000I remember one of the most moving interviews I did was a guy called Mark, who was in one of the studies in Baltimore, who was a very shy, reserved, shut down guy.
01:10:12.000When he was 10, his dad had died and no one had talked to him about his dad's death.
01:10:17.000His mother was just totally devastated and no one had talked to him about it.
01:10:21.000And he'd always been very shut down and he takes this psilocybin and he had this really intense experience where he thinks he's in space and he believed he met his father and his father apologized for leaving him and then he reached into Mark and he pulled out these walls and he said,
01:10:55.000And what an experience of egolessness can do is...
01:11:01.000Almost point a direction on a compass, right?
01:11:04.000But there's another aspect that emerged in that, which I think is one of the slight differences between us, although I think there's a lot in what you're saying.
01:11:11.000So in London, they did this research with chronically depressed people.
01:11:15.000And Robin Carhart Harris, who led that study, said to me, you know, there's one woman, chronically depressed, she takes the psilocybin, she gets everything you're saying, the dissolution of ego, the need for all the things you're talking about.
01:11:27.000And then she goes back to her job in a shitty seaside town where you just can't live compatible with those insights, right?
01:11:46.000And I think you would probably agree that there are some people who are, you know, through no fault of their own, like a lot of my relatives, Fucking stuck right and then very few people have no margin of change But a lot of people have such a small margin of change that that margin will not carry them out of depression or anxiety or addiction and that's why We need the widest what the World Health Organization says you need social solutions as well as individual solutions We need to change the way the society works in all sorts of ways That reduce
01:12:16.000the things that are causing this pain in the first place.
01:12:19.000Yes changing the way society works though is a grand in Entangled, gigantic undertaking.
01:12:28.000Whereas changing your own life is not.
01:12:32.000It can be very difficult for a lot of people, but it's far easier than changing society.
01:12:38.000So this woman who you're telling me Has this psychedelic experience, experiences this dissolving of ego, this beautiful spiritual awakening, but then goes back to her job.
01:12:48.000That's like opening up the folder of my old bullshit.
01:13:14.000But I think, actually, and this might sound strange, in some ways I think changing the society is easier than isolated individuals changing themselves.
01:13:27.000If I think about the incredible transformation I've seen in my life, so I tell the story in Lost Connections about my friend Andrew Sullivan, right?
01:13:34.0001994, Andrew was diagnosed with HIV. His first thought was, I deserve this.
01:13:39.000He'd been raised in such a homophobic world.
01:13:42.000He thought, you know what, I deserve to have this...
01:13:51.000And he goes to Provincetown, a little town in Cape Cod, to do what he thought would be the last thing he would ever do, right?
01:13:58.000And he wrote a book about a crazy utopian idea that he thought, this is never going to happen.
01:14:03.000I'm never going to live to see this, but maybe generations from now this will happen.
01:14:06.000It was the first book ever arguing for gay marriage, right?
01:14:09.000And if I get depressed about this, I try to imagine going back in time and saying to Andrew, OK, I've got some good news.
01:14:14.00025 years from now, you're going to be alive, but that's not the good news.
01:14:18.000The Supreme Court of the United States is going to quote this book in their ruling, making it mandatory for all states in the United States to introduce gay marriage.
01:14:26.000And the next day you'll be invited to the White House, which will be lit up in the colours of the rainbow flag, to celebrate with the president.
01:14:32.000And by the way, that president is going to be black.
01:14:43.000What you can do is focus on changing yourself.
01:14:46.000Actually, gay people would be really fucking miserable if that's what they'd done, right?
01:14:50.000If that's how it was, my life would be immeasurably worse if gay people had just said, you know what, it's so hard to change society, let's change ourselves.
01:14:57.000We would have remained trapped in shitty, awful institutions and systems that kept us down.
01:15:03.000I actually think, if I think about most of the people I know who are depressed, to be honest, their margin for individual change is limited, but banding together their margin for change is huge, right?
01:15:13.000Think about what we're talking about, universal basic income, for example, right?
01:15:26.000It's far easier to explain to one person, one life, why it's wrong to be homophobic than it is to change all the rednecks and all the ignorant people who don't read and all the people who have deeply ingrained archaic religious ideas about homosexuality.
01:15:41.000It's far easier To educate and illuminate one person.
01:15:46.000And it also can be done with the aid of psychedelics, especially MDMA therapy.
01:15:51.000That's one of the things that MAPS is doing right now with MDMA therapy.
01:15:54.000And they're involved in a bunch of clinical trials right now, helping people with all sorts of traumatic stress experiences, soldiers, people that experience physical violence.
01:16:05.000It's all these people that are, it's helping them alleviate a lot of the problems of their life.
01:16:10.000There's patterns that people are, that they have in their mind that they can release.
01:16:16.000You can release and you can be educated and you can understand, you can change and grow as an individual.
01:16:22.000It's far easier to do that with one person, for one person to change their life, than to change the entire culture.
01:16:28.000I do agree that there have been great strides in this country when it comes to discrimination, when it comes to racism, when it comes to so many different ideas.
01:16:35.000I think that's Connected to the exchange of ideas that we're experiencing now because of the internet.
01:16:41.000I think because of the fact that there's so many different arguments back and forth and there's so many different ways to approach things that people are being forced to change their opinions.
01:16:50.000Even more religious people today are more open to homosexuality than they have been in the past.
01:16:55.000I really believe that is a factor of all the information that's available and the amount of communication.
01:17:03.000The amount of gay people that people know from television, from news programs, from all these different talk shows where they get a different sense of, you know, you see Ellen every day.
01:18:35.000And you want to deal with all of them.
01:18:38.000I wouldn't want to get into an argument with you where it's like you're saying we should deal with the psychological factor and I'm saying we should deal with the social factor.
01:18:50.000But I think that the idea that So, like, think of what you're saying in terms of people living unfulfilled lives, living in jobs or working in jobs that they don't enjoy, where they're being controlled by a boss.
01:19:06.000It's far easier for one person to choose to change the path of their life than to try to restructure society where that doesn't exist anymore.
01:21:06.000Yeah, yeah, but I mean it could just as easily be many places spent a lot of time in the US. In fact, I think there's more people with this problem in the US. You know, now, That's a tough case.
01:21:18.000Anyone who has any margin of change, I go through in Lost Connections, the seven ways you can change your life that the science shows will reduce your depression and anxiety, very likely, right?
01:21:30.000I think the only disagreement between us is I think you're more...
01:21:34.000You think more can be done by individual will alone than I do probably.
01:21:38.000And I would say, but that's not disempowering in the sense that I would say the most powerful, individually empowering thing you can do is band together with other people like you and fight for something better, right?
01:21:56.000And one of the most moving things I learned about for the book was this incredible protest movement in Berlin that I can tell you about if you want, that transformed really is one of the places where so much of what I learned from these scientists really fell into place with me.
01:22:10.000And it was where very isolated people came together and just said, you know what?
01:22:16.000We're not going to take this anymore and fought for something better.
01:22:19.000I can explain that it's a longer story, but if you want me to tell it, I will.
01:22:26.000But I would also say it may be that what you like to do, and actually because we're a social species, this is what most we like to do, is get together with the people around you and fight for something better.
01:22:35.000And I think you're totally right about how this played out in the...
01:22:38.000Dynamics around the election, I remember, so it really haunted me.
01:22:42.000I was with some people who were doing some get out the vote work in Cleveland.
01:22:47.000And I don't know if you know Cleveland.
01:22:48.000I mean, it's like Detroit without the poetry of the ruins, right?
01:23:37.000But just about this street, there was this...
01:23:40.000We're going down the street, a third of the houses have been demolished, a third were abandoned, a third still have people living in them, some of them literally behind barbed wire, right?
01:23:49.000Sounds like a children's math problem.
01:23:52.00015 people live in this place, and they do heroin.
01:23:55.000If they walk to the end of the street, how long does it take?
01:24:40.000And it made me think about this, this other research I was thinking about as you were saying this, I think relates to the individual versus collective debate that we've kind of been touching on.
01:24:47.000So, Native American groups in Canada, they call them First Nations groups, have really high suicide rates, right?
01:24:55.000And this professor I got to interview, Professor Michael Chandler, did this really big research on this, because what he realised is that 196 First Nations groups in Canada, some of them have really high suicide and some have none, right?
01:25:08.000So he spent 10 years researching this, discovered loads of things.
01:25:11.000But one of the things he discovered was some of these groups have basically been able to fight to regain control of their community, right?
01:25:18.000They've rebuilt their language, they've rebuilt their control of the schools and, you know, whatever.
01:25:24.000And some have just been so kept down that they haven't been able to do that.
01:25:29.000Suicide rate correlates really tightly with the amount of control they were able to regain over their community.
01:25:33.000And the amount of meaning that you find in your life.
01:25:49.000If someone's listening to this and they're lonely and isolated, you know, because we're such a fractured society and because we find it so difficult to be present with each other, right?
01:25:56.000The constant distraction and refracting everything through screens, which makes us feel like, shit, I can talk about some of that if you want.
01:26:07.000Actually, that initial step is quite hard because we're so broken up, right?
01:26:12.000Listen, it's not just the initial step.
01:26:13.000It's you've gone too far in one direction.
01:26:17.000If we all start at this neutral point, right, and someone like Jamie...
01:26:23.000Does what he wants to do and finds a good path and starts going in that direction and keeps improving his life and then eventually is a happy human being as an adult.
01:26:33.000Or you have someone who goes the wrong way.
01:26:36.000They get addicted to food and cigarettes and drugs and antidepressants and they get into bad relationships and then they have...
01:26:44.000Children that they have to take care of and they have a job that they hate and then they find themselves at 37 years old looking like they're 65 trying to figure out how to get back.
01:26:52.000Well, they've got to find a way to not just move ahead, but to get back to that neutral point.
01:26:58.000So they have to go back in time over all the shit they fucked up and they have a far longer path.
01:27:04.000So it's not an impossible path, but it's a far longer path.
01:27:08.000If you all If everyone's going in a direction and that direction is 25 miles away, but you go 37 miles backwards, you have to go 37 miles forward and then the additional 25 miles.
01:28:03.000You have to say, I am better than I was yesterday, tomorrow I will be better than I am today, and I am on the right path.
01:28:09.000And there is a lot of deep satisfaction and happiness in being on the right path.
01:28:15.000Now, if you're a person who wants to be an author, but instead you're an accountant, every day you spend not feeding that idea that you can be an author is gonna chew away at you, it's gonna chip away at you, and it's gonna move you away from that neutral point many,
01:28:34.000And I think that the, that thing about when people realise they have agency, that's one of the most, because especially, and it goes back to what we were saying about work, if you are spending nine hours a day being controlled, one of the things you do to get through that is a process of internal deadening,
01:28:50.000I remember talking to Joe, the guy in the paint store, who would say, you know, I would just go home, and initially it was alcohol and then later Oxy, He would just want to numb himself, right?
01:29:02.000Because there's an internal deadening you have to do to get through that, which is why I think one of the key aspects that I talk about in Lost Connections is this transformation of work.
01:29:08.000If the thing that most people are doing most of the time is making 87% of us, we don't like it at best, You've got to go to the heart of that, right?
01:29:18.000And, you know, we're talking about margins of change.
01:29:21.000People who set up that bike store in Baltimore, they were working class people, you know, who had not had fancy educations.
01:29:27.000They set up a democratic cooperative, right?
01:30:04.000So I think he would be an illustration, or the rats in Rat Park, right?
01:30:10.000If you're in that isolated cage, I mean, it's not a great example because, you know, the rat can't leave the cage, whereas you could argue.
01:30:18.000You could attribute it just to individual...
01:30:20.000I know this is not what you're doing, but I think some people attribute this just to It's definitely not what you're saying, but just to individual weakness or individual failing, when I think that individual psychology is a significant component alongside other components.
01:30:39.000I don't think of it as individual failing.
01:30:40.000I've made many, many poor choices in my life.
01:30:43.000Here's one of the big ones you could tell people.
01:30:45.000Because there's a lot of people that are listening to this at various stages of their life.
01:30:49.000If you're young and you have an open future, you don't have massive obligations and debt and all the different things that become a real hindrance as you get older, move towards a direction that is attractive to you.
01:31:02.000Do not move towards a direction that is safe.
01:31:53.000Because if you don't do it, you don't want to be a 60-year-old man sitting around just depressed and crying.
01:31:58.000And then maybe you call your friend up who does do that for a living and he's having a great time and he just released his new album and you both started out together in high school and now here you are at different stages of your life and you haven't pursued your interest.
01:32:29.000I think universal basic income is probably a way that that's going to start happening.
01:32:34.000That can help a lot of people where your basic needs, your food is taken care of.
01:32:40.000And I think President Obama talked about this towards the end of his term, partly because he said, look, actually, I don't want to attribute this to him.
01:32:46.000I can't remember if he said it made this point in this way, but he was interviewed at Wired Magazine, and he said he thinks this will have to happen in the next 20 years, partly because of the extraordinary disruption that's coming to the economy through, you know, robotization.
01:33:01.000Yeah, well, I think Elon Musk is saying it for a slightly different motive in that he knows the pitchforks are going to come for people like him and Mark Zuckerberg.
01:33:06.000The anger is going to be directed at Silicon Valley if there isn't a universal basic income.
01:33:10.000I'm sure they have genuine concern for people as well.
01:33:13.000So you think that's really why he's saying that?
01:33:23.000Someone said, you know, the path the economy's on, there's going to be seven tech billionaires and everyone else employed to give them massages, right?
01:33:31.000And I think there's something going on here, which is I think they know at some level if they don't start providing some, if the society doesn't start providing some baseline of security.
01:33:54.000They're mostly men with low educational attainments for various reasons, a lot of which are not their fault.
01:34:01.000And, you know, that's devastating, right?
01:34:04.000So I think you're right that a universal basic income is one of the important strategies that can kind of deal with that.
01:34:10.000But I think this comes back to, I think you're going back to a thing that is a kind of recurring theme in this conversation, which is, you know, for both my books, for Chasing the Scream and for Lost Connections, looking at addiction and depression and anxiety, Both of them required me to go all over the world and just look at really different places that do things really differently.
01:34:29.000And there were some things that just recurred for both, right?
01:34:32.000I'll give you an example with addiction.
01:34:34.000The places that have most reduced addiction have not been the places that have said, I'm not attributing this to you very clearly, you're not saying this, but the places that have said, this is a problem for the individual and the individual needs to fucking sort themselves out, have a massive and growing addiction crisis.
01:35:20.000They set up a panel led by an amazing man I got to know, Dr. Hua Gu Lao, and they said to this panel, you guys go away, figure out what would actually solve this, and we've agreed in advance we'll do whatever you recommend, right?
01:35:32.000So they'd be like if Trump and Chuck Schumer and Nancy Pelosi agreed, everyone would abide by finding on this.
01:35:38.000So they go away, they look at all the evidence, including Rat Park, loads of the things we've talked about.
01:35:42.000They came back and said, decriminalise all drugs, from cannabis to crack, everything, but, and this is the crucial next step, take all the money we currently spend on fucking people's lives up, on arresting them, shaming them, stigmatising them, imprisoning them.
01:35:54.000And spend it instead on turning their lives around.
01:35:57.000And interestingly, it wasn't really what we think of.
01:35:59.000There was a little bit of residential rehab.
01:36:01.000Most of it was a big program of job creation.
01:36:04.000They set up microloans so people with addiction problems could set up and run small businesses about things they cared about.
01:36:10.000They set up a big program of subsidized work.
01:36:13.000You know, say you used to be a mechanic, they go to a garage, they say, if you employ this guy for a year, we'll pay half his wages, right?
01:36:19.000The results in Portugal have been incredible.
01:36:21.000According to the best scientific study published in the British Journal of Criminology, injecting drug use fell by more than 50%.
01:36:30.000One of the things that was so striking there was going around speaking to people.
01:36:33.000I mean, one of the most moving interviews I did for Chasing the Scream was with a guy called Juan Figueroa, who was the top drug cop in Portugal.
01:36:39.000And he led the opposition to the decriminalisation when it first happened, right?
01:37:16.000And what Portugal has done should be studied by our country, which is now falling right back into the old Nancy Reagan, just say no bullshit days with Jeff Sessions at the helm of catastrophe.
01:37:27.000He's a terrifying person in that regard because he's so ignorant as to what's going on.
01:37:36.000And the pattern is terrifying because they're trying to call Kratom an opiate right now.
01:37:43.000There's all sorts of resistance to what we know of as safe alternatives to pharmaceutical medications like CBD. That's another one they're demonizing.
01:37:54.000They want to categorize that with heroin and cocaine.
01:37:58.000It's a very, very weird time because there's so much evidence and so much science and so much history when it comes to things like Portugal where it's been successful to decriminalize everything and spend the money on treatment programs.
01:38:17.000You can imagine what I think about Jeff Sessions is disgusting and insane what he's saying.
01:38:21.000But my worry is it's not, well, I'm worried about Jeff Sessions primarily, but my other worry is it's not just Jeff Sessions.
01:38:27.000I actually think even our side, you know, when it comes to the opioid crisis, I think I've been talking about this in quite the wrong way.
01:38:36.000So it made me realise actually how deep this Nancy Reagan script is in the culture, that even liberals, my side of politics, have basically been saying, their story about the pharmaceutical, the opioid crisis is basically...
01:39:05.000But that story is just ridiculously simple.
01:39:08.000If that were true, antidepressant prescriptions have been given across the United States, right?
01:39:12.000If that were true, it would not make sense that the opioid prescriptions...
01:39:20.000Opioid addictions are also concentrated in the places where suicide is highest, where depression is highest, where, of course, there's some everywhere, but there's a reason for that, right?
01:39:30.000Angus Dayton, the economist who studied this, described the opioid deaths as despair deaths, right?
01:39:35.000If you go to the places where, as I know you travel around the country, when I go to places that have been most affected by the opioid crisis, What's going on?
01:39:44.000They've been deprived of the things that make life meaningful, so they want to be anaesthetized all the time.
01:39:48.000There's a devastating line, Marianne Faithfull, who was Mick Jagger, who's best known for being Mick Jagger's girlfriend, but it kind of pisses me off because I think she's even better than Mick Jagger.
01:40:02.000So, Mariam Faithful had a heroin addiction in the 60s when she was homeless, and she has this very challenging line in her memoir where she says something like, heroin saved my life, because if it wasn't for heroin, I would have killed myself, right?
01:40:15.000And don't misunderstand what I'm saying.
01:40:17.000Heroin is not a good solution to despair.
01:40:19.000If we want it, clearly, for all sorts of very obvious reasons, If we want to understand why there's been this huge increase in opioid use, we have to understand these things that I'm writing about in this connection so that the World Health Organization is explaining this deep kind of despair.
01:40:32.000And my worry is, because you're back to the worry about how our side is getting it wrong, so we've got Jeff Sessions getting it wrong in the most obvious, insane way, right?
01:40:38.000You know, it's just we need to crack down on the Mexicans and that'll stop.
01:40:41.000The United States has spent a trillion dollars On the war on drugs.
01:40:47.000It's imprisoned more people than any other country in human history.
01:40:51.000And at the end of all that, you guys can't even keep drugs out of your prisons where you pay people to walk around the fucking perimeter the whole time.
01:40:56.000So good luck keeping them out of a country with two, three thousand mile borders.
01:40:59.000That's so ridiculous and so absurd that...
01:41:11.000I'm pretty sure all of your listeners agree with us, or pretty much all of them agree with us on Jeff Sessions.
01:41:16.000What I think more of them will be tempted by will be the more liberal argument, as a liberal, so I'm not attacking liberals, but the more liberal argument, which is this simplistic, even Bernie Sanders, who I love and would have voted for, Well, I think he's got this wrong, which is that, although I think Bernie Sanders' politics would deal with some of the deeper problems as well,
01:41:51.000Almost as, you know, not quite as bad as what's happening with opioids here, but it was massive.
01:41:55.000And Switzerland got this amazing kick-ass female president called Ruth Dreyfuss who explained to people, look, When you hear the word legalisation, what you picture is anarchy and chaos, right?
01:42:08.000What we have now is anarchy and chaos.
01:42:10.000When you prohibit drugs, what you get is unknown criminals selling unknown chemicals to unknown drug users, all in the dark, filled with violence, disease and chaos.
01:42:19.000What she proposed to do is legalise heroin, right?
01:42:22.000And it's important to understand what that doesn't mean.
01:42:24.000Doesn't mean there's like a heroin aisle in the CVS in Switzerland, right?
01:42:28.000So different things can be legalized differently.
01:42:30.000I don't know the rules in LA, but I'm pretty sure you could legally, if you wanted to, own a dog, a monkey, and a lion.
01:42:37.000But I'm pretty sure the rules are different, right?
01:42:39.000Yeah, I don't think you can own a monkey or a lion, but you can definitely own a dog.
01:42:41.000If you really wanted to one and you were rich, you could get them in Texas.
01:42:45.000You could do whatever the fuck you want, except you can't have pot in Texas.
01:43:17.000You've got to use it there and then you leave and you go to your job because they do two things and it's the exact opposite of what's being proposed in the US. What's being proposed in the US is stop prescribing And don't give support, right?
01:43:29.000Well, Switzerland is the exact opposite.
01:43:31.000In Switzerland, they'll give you the drug you're addicted to, and then they give you loads of support to figure out why you're in such pain in the first place.
01:43:38.000They help you get housing, they get you subsidized work, they give you loads of therapy.
01:43:46.000Well, that's probably one of the very best ways for people to quit drugs, especially some horrible drug.
01:43:52.000And it's a ruthlessly introspective drug that many, many people have found great success in kicking heroin, cigarettes, alcoholism, getting over past abuse.
01:44:31.000I would really recommend people look at his work.
01:44:32.000But in terms of, just to stay with the last point about Switzerland, because there was something really, I think it relates to Iboga in a way.
01:44:37.000So one of the things that really surprised me in that guy spending time in that clinic, I remember this chief psychiatrist there, Dr. Rita Mangies.
01:44:44.000So they will give you any dose you want, except one that will kill you, and there is never any pressure to cut back, which really surprised me.
01:44:54.000So you could go to this clinic and they'll dose you up with heroin?
01:45:07.000So, headline, most important fact is, there have been zero heroin overdose deaths on legal heroin in Switzerland in the 12 years that program has existed.
01:45:21.000There's been a really significant fall in heroin use.
01:45:22.000The best research is by Professor Ambrose Uchtenhagen, who's shown there have been no deaths in the legal program and an enormous fall in deaths in the illegal program, and enormous fall in use overall, for various reasons I can talk about.
01:45:33.000But the thing that blew my mind was they give them whatever days they want for as long as they want.
01:45:37.000And I was like, what we're told, so it comes back to chemical hooks, what we're told is they'll just want more and more forever, right?
01:45:54.000And she looked at me like I was an idiot.
01:45:55.000And she said, well, people's lives get better.
01:45:59.000And as their lives get better, they don't want to be anesthetized so much.
01:46:02.000Which seems almost stupidly obvious, right?
01:46:04.000It goes right back to what you were saying about antidepressants and people's lives.
01:46:10.000Like, the choice that you make and the paths that you take and the people you surround with and the happiness that you feel from your community, that's ultimately what leads to a fulfilling life.
01:46:19.000And if you have all that, why would you fuck it up with heroin?
01:46:55.000I know some people that are older men that have been bachelors their whole lives and they're childless and now they don't have a deep connection with anybody and they get to this very weird, strange place where they're like,
01:48:28.000So when you look at these men, if you have an isolated...
01:48:32.000There was this woman, so I covered this incredible protest movement that happened in Berlin on a big anonymous housing project where no one knew each other and they came together to protest.
01:48:43.000It was a woman who was about to kill herself because she was about to be evicted and the whole housing project came together to say she should be allowed to stay in her home and they should have a rent freeze.
01:48:52.000And it's an amazing story, I tell it in the book, but there's something one of the women said to me that I never forgot.
01:48:59.000She'd grown up in Turkey and she'd come to Germany I think when she was 17. She said, when I grew up in Turkey, what I called my home was my village and everyone in it.
01:49:08.000And then I came to live in the Western world and I learned that what you're meant to call home is just your four walls and if you're lucky your family.
01:49:16.000And then this protest began, and we all got to know each other, and this whole place became my home.
01:49:23.000And I think of everywhere here as home now.
01:49:25.000And she realised that we are homeless in some sense in the Western world.
01:49:30.000That us humans have a need for a sense of belonging.
01:49:34.000And our sense of home is too small to meet our sense of home belonging.
01:49:37.000There's a wonderful Bosnian writer called Alexander Heyman, who said, home is where people notice when you're not there.
01:50:31.000But also, to me, the biggest problem with just telling this exclusively biological story about depression and anxiety, there's some real biological factors of course, It cuts us off from having this conversation, right?
01:50:42.000All those people you were talking about who are so insistent, as I was, that their depression is just the result of a chemical imbalance, If you think that, it disconnects you from the source of your pain.
01:50:52.000It tells you you're just biologically broken, and presumably always going to be biologically broken.
01:50:58.000When the conversation we're having, which is a different conversation, it's a difficult conversation, it's a nuanced conversation, it's not simplistic, it's not one problem, one lever to solve it, it's a much deeper and more textured way of thinking, That is the conversation we have to have.
01:51:14.000That's what the best scientists in the world are telling us, the World Health Organization.
01:51:18.000And my worry is we're just being pushed in, like you said, that very good metaphor about driving 37 miles in the wrong direction, right?
01:51:25.000We're just driving in the wrong direction.
01:51:27.000We're driving away from the source of our pain rather than towards it where it can be understood and solved.
01:51:32.000Of course, there's always going to be some pain in human life, but the fact that we have this one in five people taking a psychiatric drug, you know, I think the figure is one in ten 13-year-old boys is taking a stimulant drug to make them focus.
01:51:45.000I think the figure is 30% of old people in retirement homes have been given antipsychotic drugs to shut them the fuck up because they're rebelling against the way they're being treated.
01:51:54.000In between, one in four middle-aged women in the United States is taking a chemical antidepressant at any given time.
01:52:02.000You're talking about a society that, I mean, the figures about how many children, it's much lower, but it's so much more extreme.
01:52:09.000The number of toddlers who've been given anti-psychotics in the United States is just off the scale, right?
01:52:15.000I think Dr. Sami Tamimi has written about this.
01:52:18.000There's some extraordinary figure, I might be getting the figure slightly wrong, but it's something like a majority of children in foster care in the United States are being given stimulant drugs.
01:52:51.000A lot of the causes of depression and anxiety that I wrote about, I couldn't help but notice reading all the research, interviewing the scientists, also can lead to decrease in focus and attention.
01:53:05.000So for example, if you are deadened at work and you feel controlled all the time, you have to deaden yourself to get through it, It's harder.
01:53:44.000If you're on your own in the savannas of Africa, you want to be hypervigilant.
01:53:48.000One of the things that was most challenging to me is this evidence that The people with the lowest levels of attention problems and depression and anxiety in the United States are the Amish, right?
01:54:04.000So the idea of learning something from the Amish was initially challenging to me.
01:54:08.000And I've got to admit, I felt really humbled by going and spending time.
01:54:11.000I went to this village called Elkhart La Grange, which is just outside Fort Wayne in Indiana.
01:54:16.000And, you know, there's still a lot I disagree with about the Amish, don't get me wrong.
01:54:20.000Not least because I just re-watched Witness.
01:54:22.000But, you know, I could see that they've got...
01:54:27.000So there's a very interesting thing about the Amish, as you know, when you turn 16, if you're an Amish, you've You've got to leave and go and live in what they call the English world, our world, right?
01:54:36.000And then you decide whether to come back.
01:54:37.000About 80% decide to come back, 20% don't.
01:54:39.000It's one of the reasons why the Amish is never counted as a cult, because no cult would do that, right?
01:54:44.000No cult's going to tell you to leave for two years and then decide whether to come back.
01:54:52.000And I remember having this very challenging conversation with, what's his name, Lauren Beachy, his name is an Amish guy there, who said, it comes back to the weight conversation we had.
01:55:01.000He said, look, there's loads of things I miss.
01:55:03.000He talked about missing that 70s show.
01:55:05.000He said, I used to love driving in trucks because they obviously don't drive, they don't use electricity off the grid.
01:55:11.000And he said, but you know, if I kept those things, I wouldn't spend time with my family, I wouldn't spend time with my children, I wouldn't know who my neighbours were.
01:55:18.000And he said this very challenging thing.
01:56:23.000There's so many things that they don't do.
01:56:25.000So because of their culture, they're making their own homes, right?
01:56:29.000So they have a vested interest in helping each other, working together as a community, and they have a deep sense of satisfaction of constructing each other's homes.
01:56:45.000There's a real connection with where they get their food from, a real connection with where they live, their community, the sense of Just the sense of belonging to something that's bigger than you.
01:56:58.000There's so many factors involved in their happiness that you can kind of see where, yeah, there's a lot of wacky shit with the cult aspects of being an Amish person, but...
01:57:10.000What you get out of it, it's almost like if you had a self-help group that subscribed to all the positive benefits of being Amish, and they just called it, like, re-grounding or something like that, and you just go out there and you become a part of nature.
01:57:41.000But it's not like they're not holding them back.
01:57:45.000I think that's one of the things that I think about this in relation to attention is so there's this theory that Amish kids don't seem to develop ADHD right and there's been it's been surprisingly understudied.
01:58:04.000I wondered if it was that and I also wondered if it was like they don't have electronics so then obviously I'm kidding and I think there's an element going on there but actually Yeah.
01:58:37.000But what we do is we try to bash every child into one particular mode of being, which actually is designed to prepare them for shitty deadening work.
01:58:47.000The reason our schools are shitty and deadening, there's a guy called Alfie Cohn who says every school has an official curriculum and a hidden curriculum.
01:58:54.000The official curriculum is like history, geography, whatever.
01:58:57.000And the hidden curriculum is, this is what we're training you to put up with in your life.
01:59:02.000And if you've got a society where 87% of people don't like their work, and you're almost twice as likely to hate your job as love your job, part of the job of the school system will be to deaden children so they learn you've got to fucking sit there and shut up and do what you're told,
01:59:18.000So that's not a malfunction of the system, that's an unconscious function of the system, right?
01:59:22.000So we've got this system where we're bashing these kids to prepare them for this economic system that's making us feel miserable, To me, the solution is to change the way we work so we don't have to fucking deaden our children, right?
01:59:33.000So that actually our children can be...
01:59:35.000But the Amish who, you know, do what, as you say, it's not like they're doing...
01:59:41.000High-end cognitive labour is probably the fancy way of putting it, right?
01:59:44.000But their kids, to them, having a kid who goes fishing and running around is as valuable, actually, as it may even be more valuable than the kid who sits there reading all day, right?
01:59:54.000And I think there's a real thing about this.
01:59:57.000What that tells us, it comes back to one of the themes that's come up all through our conversation, Joe.
02:00:02.000These things that we're told are pathologies make sense in their contexts, right?
02:00:07.000Depression, we're told it's a pathology.
02:00:09.000Actually, anxiety, we're told it's a pathology.
02:00:11.000Actually, it's largely, not entirely, but largely a response to things going wrong.
02:00:46.000For Chasing the Scream, my book about addiction and the drug war, I went out with a group of women...
02:00:52.000In Arizona, in that prison run by that fucking psychopath Joe Arpaio, who I also interviewed, who Trump pardoned, How the fuck did you pardon that guy?
02:01:05.000It's funny, I can tell you about Joe Alpaio, because in a funny sort of way, I felt very sorry for him.
02:01:09.000But anyway, I went out on this group of, with this group of women who are made to go out on a chain gang wearing t-shirts saying I was a drug addict while members of the public mock them and jeer at them, right?
02:01:21.000And I remember going back to the prison with them.
02:01:48.000It's a concrete cell, bare concrete cell, with nothing in it, no TV, nothing.
02:01:53.000And I saw this woman in there who was, when, like, she saw my face through that was just so desperate to see a human being who wasn't one of these guards.
02:02:02.000And I remember, the audio is actually on the Chasing the Scream website, chasingthescream.com.
02:02:06.000And I remember looking in this cell and thinking, This is the closest you could get to a literal human reenactment of the cages that guaranteed addiction in rats.
02:02:18.000And this is what we're doing, thinking it'll stop this woman from being addicted.
02:02:22.000All the places which had approaches based on punishment and shame towards these things, sometimes people say, oh, punishing people with addiction problems doesn't work.
02:02:35.000Those women go in fucking broken, devastated.
02:02:38.000Then they're even more broken and devastated.
02:02:39.000They go out even more fucking addicted, right?
02:02:41.000So the reason why Portugal and Switzerland have massively falling addiction problems and the United States have massively increasing ones, right?
02:02:52.000Again, the evidence is approaches towards this problem that are based on compassion, connection, love, understanding, seeing that it makes sense, work.
02:04:06.000And I didn't even realize there was anything that I could do that I would be intellectually curious about.
02:04:12.000I mean, I didn't think that that was a part of my life.
02:04:15.000I didn't think I was a curious person.
02:04:17.000It was just merely because I was being forced to do a bunch of shit that I didn't want to do, and it tainted my idea of learning.
02:04:24.000And when I got out of school, and then when I started reading books just for my own amusement and interest, then I realized, oh, I'm a very curious person.
02:04:33.000I just didn't want to do what they wanted me to do.
02:04:36.000I didn't want to study what they wanted me to study, and I didn't want to be stuck in some room with some person who was under-motivated and really didn't have any understanding of how to deal with children.
02:04:46.000It was the rare person, one out of five, one out of six teachers that would come along that would give you some spark of happiness and love, and you would go like, oh, this class is pretty cool.
02:05:01.000Most of the time, it was a dull grind.
02:05:03.000And I would wake up with nightmares after I had graduated that I had fucked up and didn't get the right amount of credits and I had to go back to school.
02:05:11.000I would have crazy nightmares that I would have to repeat the 12th grade and go back to school because it was soul-sucking.
02:05:19.000And to me it represented the future because the future was going to be more soul-sucking because you're going to be working 40 hours a week plus overtime doing something that you hated and this is what you had to do if you wanted to get by in this life and that is what was presented to me and that's what's presented to a lot of people and if you take that And keep going with it,
02:05:37.000you eventually become that guy who's in that job, and then you say, well, maybe I'll get some happiness if I get a nice car.
02:05:43.000And so you take out a lease on a nice car, and then now you have this debt that you have to pay.
02:05:48.000So now you have to keep working, and you keep working so you can keep this car.
02:05:51.000Well, I'm gonna get a condo, and then you get a condo, you got more debt.
02:06:41.000Far more human beings have lived in the way the Amish lived than have ever lived in the way we lived.
02:06:45.000Now, I don't want to go fully back to the Amish, obviously, But there are lessons we can learn from all these things that we're talking about, about reconnection to meaning and purpose.
02:06:52.000And part of what you're saying is, we live in a landscape that has been constructed not to serve people, but to serve corporations, right?
02:06:59.000This very unusual recent human innovation.
02:07:02.000As I said, imagine if every corporation was converted into a democratic cooperative.
02:07:06.000Imagine everyone listening to this tomorrow knew they were going into work in a place where if there is a boss, he's elected by them, he's accountable to them, where you decide the priorities for your workplace with your colleagues by voting, maybe once every three months, once a year, whatever.
02:07:23.000That's a very different way of living and thinking about the things we do most of the time.
02:07:27.000And that would, again, require a school system that prepared people to be citizens, taking part in a workplace, not, as you put it brilliantly, like robot workers, you know, just passively receiving orders.
02:07:41.000Now, lots of people are making that transition, you know, like the people I talked about in Baltimore Bicycle Works who've made that transition on their own.
02:07:49.000These are big social changes we can make.
02:07:52.000And again, one of the things that's so important is about saying to people, like, it sounds to me like no one said to you, Joe, the fact that you fucking hate this school is a sign that you are more likely to be successful, not less, right?
02:08:04.000The things that will make you a success in your life Are the things that this school is trying to beat out of you, right?
02:08:10.000I presume not literally beat out of you, but mentally beat out of you, right?
02:08:14.000And in a sense, that's what we need to say to a lot of people about a lot of these forms of discomfort.
02:09:14.000That's a real problem with kids that don't have to do well.
02:09:16.000But I think you've got a society that drugs kids at the bottom to shut up.
02:09:20.000These kids in foster care who are traumatised, not being looked after.
02:09:23.000They're being drugged to just basically make them docile.
02:09:25.000You've got kids at the top who are drugged to make them compete.
02:09:29.000You know, I've got a friend who's a Wall Street banker who put his kid on, I can't remember if it was Adderall or Ritalin, one of the stimulant drugs when he was a young teenager, because he said, but every other fucking kid in the class is on it.
02:09:41.000So if he doesn't go on it, He's falling behind, right?
02:09:46.000So you have, I mean, what a sick culture that's giving their children a cocaine-like drug to make them compete in an unnatural way.
02:10:18.000And then, but then you have this real problem where actually if you then take the kid off it, they will experience really severe withdrawal, right?
02:10:25.000And often what that's misinterpreted is, oh my God, look at what happens to my kid when I take him off it.
02:10:29.000He goes, it's like, no, that's not the baseline of your kid.
02:10:32.000That's your kid in withdrawal from a cocaine-like, remarkable...
02:10:37.000I've spoken about this before so I think I can say I had a very close relative who had a cocaine addiction and I remember at the height of her cocaine addiction she had a young relative of mine, I'm trying to phrase this ambiguously, who she was drugging with Ritalin,
02:10:52.000the doctor had given it, because he didn't want to focus because he was traumatised because his mother was a cocaine addict, right?
02:10:58.000And I remember she used to drive into school in the morning, she would snort a line of coke before she went, and then in the car he'd have to swallow his cocaine-like pill.
02:11:07.000And I thought, what a crazy culture that her cocaine use is illegal and would end up with her being criminally punished, and his cocaine-like substances required by the police.
02:11:19.000Not required by the police, sorry, required by the school and mandated by the doctor.
02:11:23.000What a crazy, what a culture that is fucked up about how it thinks about altering itself chemically, about children, about connection, and that my relative was very deprived of the capacity to understand what was happening to her.
02:11:37.000This is the cruelest thing we've done.
02:11:38.000If you just give people these ridiculously simplistic stories about addiction, it's just the chemical hook.
02:11:43.000Or this ridiculously simplistic story about depression, it's just a chemical imbalance.
02:11:47.000It's like we say, you cut them off from understanding the thing that's right in front of them.
02:11:51.000And sometimes I think with both my books, with Chasing the Scream and Lost Connections, at times I thought, do I even need to say this?
02:12:06.000It's a very unusual position to be in a position where you're saying something that is both unbelievably obvious and really quite radical, right?
02:12:43.000So there were a few points that have been made.
02:12:45.000There were a few pieces that were written as soon as the book came out by psychiatrists who admitted that, to be fair to them, they hadn't read the book.
02:12:51.000And they were responding to an extract from the book.
02:12:54.000And obviously in an extract, you can't make every point you want to make, right?
02:13:00.000So what they thought I was saying is, even though the piece, I think, very clearly didn't say this, what they thought I was saying is, chemical antidepressants are bad for everyone and people should stop taking them.
02:13:09.000If I had said that, it would be totally right to criticize me.
02:13:41.000For her, 1.8 points on the Hamilton scale is worth having.
02:13:45.000But it's not solving her problem, right?
02:13:47.000It's not solving the problem for the vast majority of people.
02:13:49.000And so I think there's been some criticisms that are He's telling people to stop.
02:13:56.000That's a dangerous and terrible thing to do.
02:13:59.000So my response to that is, read the book, because I don't say that.
02:14:02.000In fact, I say explicitly, you should carry on taking them if for you the benefits outweigh the side effects.
02:14:07.000Another criticism, which I have more sympathy for in that I understand where it's coming from, is it's more like an ideological misunderstanding.
02:14:16.000Like we're saying, we live in such an individualistic culture that if someone comes along, so we basically think there's two ways of thinking about this, right?
02:14:24.000Either your depression, your anxiety, your addiction are due to a biological problem, in which case you deserve love and support, or If you dismantle the biological story, what a lot of people hear is, oh my God, you're saying it's my fault that I'm a fuck-up,
02:14:39.000that I've got to solve this on my own.
02:14:41.000And lots of people go, well, I can't fucking go and democratise my workplace.
02:14:45.000I can't fucking go and, you know, take a load of ayahuasca and learn.
02:14:50.000They're just saying, what are you talking about?
02:14:52.000And I think because I'm talking in this third category, which is...
02:14:57.000Biology is real, psychology is real, but most of the drivers of this are social, they're in the way we live.
02:15:03.000Because for so long we've been trained to not think in social terms, I think a lot of people just literally don't get what I'm saying, right?
02:15:10.000When I was a kid, Margaret Thatcher said, the Prime Minister at the time said, there's no such thing as society, there's only individuals and their families.
02:15:18.000Now, I never liked Margaret Thatcher, but...
02:15:20.000This debate has made me realise how much I internalised that, right?
02:15:37.000And I think we've so, we've so individualised and internalised, we've so internalised this individualism that I think people understand, and again, they were riffing on the extracts, these are not people who read the book, in the main.
02:15:49.000But I think it was kind of understandable for them to be like, fuck you, I can't do that.
02:15:56.000I wouldn't push back on them so hard because they think, well, there are narrow margins and this is why we need to change.
02:16:01.000And people get that if you talk about car accidents, right?
02:16:06.000Individual drivers should drive safely, but we don't just leave car safety up to that.
02:16:12.000We have airbags and seat belts and speed limits, driving tests, we arrest people under DUIs, right?
02:16:19.000If we just took away all those things and just said to individual drivers, hey drivers, do it, and pedestrians, pedestrians take care, drivers take care, we would have far more people dying in car accidents than we do now, right?
02:16:29.000So I accept that there's an individual role, but there's a social role, right?
02:16:33.000The whole society deals with the problem of car accidents.
02:16:36.000And what I'm saying is the whole society should deal with the problem of depression and anxiety.
02:16:39.000We need social changes, like democratising workplaces is one we've talked about a lot, that reduce the reasons why people are so depressed and anxious in the first place.
02:16:46.000But I think in a society that has so devalued the idea of the social...
02:16:51.000I may as well be speaking fucking Swedish for all they could understand.
02:16:55.000Yes, I think they're just neglecting to consider the possibility that some of the factors are because of your life.
02:17:01.000And the social aspects, the physical aspects, the exercise, the diet, all those various things.
02:17:08.000There's many, many people that just are neglecting to take those even into consideration.
02:17:12.000I also think people work way too much.
02:17:16.000I don't think that's the way to live your life.
02:17:18.000I think we've got a really bad system and I think this system has existed for so long that we assume that this is the only way to live that you have to do a 40-hour work week.
02:17:45.000Have a fucking work day and have a day where you don't work.
02:17:48.000If you choose to work more because you're trying to pursue something and you're a dedicated person, you have a job, that's one thing.
02:17:56.000I just think this soul-sucking grind of, you know, getting out of college at 21 and grinding until you're 65, and then you look forward to your golden years.
02:18:54.000I entirely agree, obviously, people should not be judged for their anxiety, depression, or addiction.
02:18:58.000But actually, there's a really interesting experiment that showed that this is just a complete...
02:19:01.000This first triggered me on this is I interviewed an amazing neuroscientist called Mark Lewis, who I was talking about this, and I said, you know, I'm worried because he's been explaining a lot of the things we've talked about to me early in my research.
02:19:11.000And I said, you know, I'm worried about this, Mark, because won't this just reintroduce stigma, right, if we're saying it's not just biological?
02:19:16.000And he said, Johan, did anyone ever doubt that leprosy or AIDS were biological problems?
02:19:25.000You might have noticed there was some stigma against leprosy and AIDS. Why do you think saying something is biological removes the stigma around it?
02:19:33.000Again, it's a simple point, but I thought, wow, I'd never thought of that.
02:19:36.000But there was actually this experiment by a woman I interviewed called Professor Sheila Mehta, which looked at this question of stigma.
02:19:42.000So she wanted to figure out which is more de-stigmatising, telling people that mental health problems are caused by your biology or saying they're caused by your life.
02:19:53.000So what they do is, it's a little bit of a complex experiment, but I think it's worth explaining.
02:19:58.000Say you're the guy who's taking part in the experiment.
02:20:00.000They bring you in, and they say, before the experiment begins, we just want you to sit here and fill in a questionnaire, right?
02:20:05.000You don't realise, but this is actually the experiment.
02:20:08.000So you're sitting next to someone else who you don't realise is an actor, and you get chatting, and the actor will run it two ways.
02:20:15.000Sometimes the actor will say, I've got a mental health problem because of my biology.
02:20:20.000And sometimes he'll say, I've got a mental health problem because of bad things that have happened to me.
02:20:51.000And they wanted to see would there be a difference in how many electric shocks and how hard you hit the button depending on what you were told.
02:20:58.000What they found was you were significantly more like...
02:21:00.000You zapped the person more and harder if you thought their problem was just due to their biology than if it was due to things that happened to them in their lives.
02:21:11.000I think this is the stuff we're talking about is the path out of stigma.
02:21:13.000Because if what we're saying is there's just this class of people who are biologically different to us, and they have this flaw that you and I don't have, you can see why that leads to stigma, right?
02:21:23.000But if what you're saying is, actually, we're all vulnerable to this stuff, Actually, the things that are making some people depressed, anxious, and addicted are making loads of us just less happy than we could be, less fulfilled than we could be.
02:21:36.000What that does, instead of dividing us into two tribes, it says we're all on a continuum, and actually, the fight that will help these people who are depressed and anxious will also improve your life, right?
02:21:47.000That's, to me, a much more powerful message.
02:21:49.000Instead of the problem being an inexplicable biological malfunction, it's a Response to things that you can see in your life, right?
02:21:59.000Well, it's interesting that we've always had the term sadness, right?
02:22:02.000People have always experienced sadness.
02:22:03.000But if you go back and go through ancient literature, you don't see a lot of stories about people suffering from depression.
02:22:18.000There's always been acute and extreme unhappiness.
02:22:21.000There's always been people living unhappy lives, but the state of being depressed as being a clinical, psychological sort of diagnosis, that's relatively recent.
02:22:32.000Well, the idea that it's a pathology...
02:23:37.000Like, if you've got an issue, they've got a pill for it.
02:23:39.000You create that sort of an environment, they're going to constantly be innovating and trying to come up with new pills for new issues and even create ailments, make up ailments, and come up with solutions for those ailments.
02:23:52.000And a lot of those are actually, we've shown this on the podcast many times, those were done by advertising agencies.
02:23:58.000They've actually created names of diseases and issues.
02:24:02.000Just so they can come up with solutions.
02:24:04.000One of the things that was most shocking in the research for Lost Connections was realizing how much of what I had been told was invented, not by scientists, but by drug company PRs.
02:24:15.000So I'll give you an example, two examples, and I'm afraid I'm going to have to go in a second.
02:25:10.000And only the ones, I mean, there's one study I cite in the book, I think it was, they tested the drug on 247 people, and they only published the results for 27 of them, who you will not find hard to guess, were the 27 for whom it worked.
02:25:23.000So the early results were hugely exaggerated.
02:25:26.000You'll remember that, you know, when antidepressants were first marketed, people are told, you know, it'll make you better than well, right?
02:25:36.000Actually, Eliot Spitzer did an amazing job when he was Attorney General in New York State of taking the pharmaceutical companies to court because it particularly affected me when I read it because it was the drug that I was given as a teenager.
02:25:47.000It's called Paroxetine or Paxil in the US. The company that manufactures it literally had a leaked memo from them in which they say, this doesn't work for teenagers, but I think the phrase they used was, this would be unacceptable for the commercial profile of paroxetine.
02:26:24.000I felt a strong initial boost, and I would say it probably did give me 1.8 points on the Hamilton scale, like what we're talking about.
02:26:30.000Probably gave me a very mild boost, but it didn't solve my problem.
02:26:34.000And the problem is the story I was told about it, that this is the solution because the problem is the chemical imbalance, disconnected me from a much wider program of reconnection in my life that did in fact solve my depression when I embarked on it, right?
02:26:49.000So I think the drug companies, It's scandalous what they did.
02:26:55.000It's not that the drugs have no value, they do, but when you read through what they actually did and the way these stories were constructed and the...
02:27:08.000You know, I mean, I remember interviewing a clinical psychologist, Dr. Lucy Johnson, who's a brilliant person, and her just saying, you know, everything you were told is bullshit.
02:27:17.000And me just sitting there and going through, this is what my doctor told me, this is what my doctor told me, this is what my doctor told me.
02:27:21.000In fact, there's no repercussions, no legal repercussions against those people for doing that.
02:27:49.000I think you'd find that team would win a lot more often, right?
02:27:54.000So what we think is, oh, there's this dispassionate judge, even the way the rules are constructed.
02:27:59.000So to get a drug, I think the rules have been slightly tightened recently, but when antidepressants were first introduced, to get a drug to market, You only had to demonstrate two studies anywhere that showed any efficacy, right?
02:28:12.000So that means you could commission 3,000 studies and if two of them, it's not that the FDA would take the balance of the research, if you could show two that it worked, that would be enough.
02:28:22.000So they would present those studies to the FDA. They didn't have to show them everything they've done.
02:28:27.000There's now more publication required, which is one of the reasons why so few new chemical antidepressants are coming onto the market, because the rules have been slightly tightened.
02:28:34.000And as a result, where are all the new ones?
02:29:47.000And then have massive lesbian orgies with their vibrators.
02:29:49.000And it was in a British zoo, so these polite British parrots would be like, Mummy, Mummy, what's happening?
02:29:55.000And they'd be like, nothing, darling, come over here.
02:29:57.000But Isabel's theory is, so animals go crazy in zoos a lot of the time, right?
02:30:02.000Parrots rip out their feathers, horses start obsessively swaying, elephants will grind their tusks down to nothing.
02:30:11.000And she basically argues, this is simplifying her argument, she says there's many things going on here, but that humans are being, animals deprived of their habitat feel like shit, and we are increasingly deprived of our habitat, the habitat we evolved in,
02:30:39.000There's such an amazing study, Michigan State Prison, Just by accident, no one designed it this way.
02:30:46.000One part of it looks out over just bare concrete, and one part of it looks out over lovely green space.
02:30:53.000It was just random where you ended up, but the people who looked out over the concrete were 23% more likely to develop mental health problems.
02:31:32.000And one more time, the name of your book?
02:31:33.000So the book is called Lost Connections, Uncovering the Real Causes of Depression and the Unexpected Solutions.
02:31:38.000If you go to the book's website, www.thelostconnections.com, you can find out what loads of people from Hillary Clinton to Tucker Carlson to Elton John have said about the book.
02:31:48.000You can take a quiz to see how much you know about depression and anxiety.