Making Sense - Sam Harris - November 04, 2019


#174 — Life & Mind


Episode Stats

Length

48 minutes

Words per Minute

151.17735

Word Count

7,364

Sentence Count

531

Misogynist Sentences

3

Hate Speech Sentences

8


Summary

Sam Harris sits down with evolutionary biologist Richard Dawkins to discuss his new book, "Outgrowing God: A Beginner's Guide." They discuss Dawkins' theory of evolution, the concept of the extended phenotype, and psychedelics and meditation. And, of course, there's a brief discussion of the God Delusion. Sam and Richard discuss all of this and much more in this episode of The Making Sense Podcast, hosted by Sam Harris, and recorded at the Biltmore Hotel in Las Vegas, NV, on the last Sunday of every month. You can expect weekly episodes every available as Video, Podcast, and blogposts. Please note that this podcast is not meant to be a substitute for professional medical advice, diagnosis, or treatment of disease, which is already available on the National Institute of Neurological and Neuropsychology website. Please refer to your doctor if you are in need of medical or mental health care, or if you would like to refer to a physician. You can also contact the National Suicide Prevention Lifeline at 1-800-273-8255 or visit their website at suicidepreventionlifeline.org.org to get help with your mental health problems, including depression, anxiety, and post-traumatic stress disorder, and other forms of post traumatic stress disorder. If you are struggling with anxiety, insomnia, or another medical problem, please talk to a trained professional who can assist you. if you can be of service, such as a trained counsellor. Thank you for listening to this podcast and share it on your social media. Make sure to let us know what you think of it. Thanks for listening and sharing it with your friends and posting it on social media! It helps us spread the word about this podcast! Make sense? and other things we can help spread it around the word of this podcast. and help us spread it to the world. . Thanks again for listening thank you for your support to others like it in the making sense or share it everywhere you are listening to it! and spreading it everywhere else we are making sense, it helps us make sense, thank you, more of it, more people are listening, more than you can do it, and we are grateful for it, thanks you are helping us, more and more, and more of us are grateful, more knowledge is being heard, more


Transcript

00:00:00.000 Welcome to the Making Sense podcast. This is Sam Harris. Okay, do I have housekeeping
00:00:23.660 today? I don't think so. Today I'm speaking with Richard Dawkins. Richard really needs
00:00:32.600 no introduction on this podcast, but please note that he has a new book out titled Outgrowing
00:00:39.480 God, A Beginner's Guide. In this conversation, we mostly take your questions and we start
00:00:46.840 by discussing the strangeness of the gene's eye view of the world. We then move on to
00:00:52.240 the limits of Darwinian thinking when applied to human life. We talk about his concept of
00:00:58.360 the extended phenotype and memetics. We look at how ideologies act as meme complexes. We
00:01:07.900 talk about whether consciousness might be an epiphenomenon and therefore might not have
00:01:12.600 been evolved under selective pressure. And then we talk about psychedelics and meditation.
00:01:19.200 I actually lead Richard in a guided meditation. And the effects of that, you can hear for
00:01:27.740 yourself. And I'll have something more to say in my afterward. So now, without further
00:01:34.540 delay, I bring you Richard Dawkins.
00:01:36.580 Be you still, be you still, trembling heart, remember the wisdom out of the old days.
00:01:45.520 Him who trembles before the flame and the flood and the winds that blow through the starry ways,
00:01:50.880 let the starry winds and the flame and the flood cover over and hide, for he has no part
00:01:56.960 with the lonely majestical multitude.
00:01:59.440 What poem is that?
00:02:01.780 It's an early one. It's from The Wind Among the Reeds, I think.
00:02:05.240 Well, that was a wonderful reading and the perfect sound check. I am here with Richard Dawkins.
00:02:11.840 Richard, thanks for joining me again on the podcast.
00:02:13.680 Thank you very much. And thank you for coming to the Biltmore Hotel rather than making me go
00:02:17.720 to your studio, which I thought I should have done.
00:02:19.400 This is old school. I love it. So, you know, you and I have done a bunch of events together.
00:02:27.680 Yes, I hope we haven't run out of things to talk about. I worry about that kind of thing.
00:02:31.440 Yeah. Yeah. You know, so in the interest of not running to that problem, I decided to go out on
00:02:37.100 social media and ask for questions. And this is, you know, this is, that's the perfect algorithm
00:02:40.980 because I can, I know what kinds of questions we've hit in the past. And this simultaneously gets
00:02:47.120 us what our respective audiences want to hear. And, and I have no fear that we're going to cover
00:02:53.140 the same territory in the same way again. I hope one or two of them may have seen my new book.
00:02:57.820 Maybe not, maybe too recently out. I don't know. So let's just mention the new books just so that
00:03:02.320 we, we've done that. The new book is Outgrowing God. Outgrowing God, yes.
00:03:07.260 And this is for teenagers, right? Yes. It's sort of, quite a lot of complaints have been that it's
00:03:13.480 just like the God delusion. It actually isn't just like the God delusion. It's different.
00:03:17.120 And it's, it's sort of designed for teenagers, yes. And we can obviously spend as much time or as
00:03:23.500 little time on these questions as we want and open any doors that they suggest to us. But the first
00:03:30.460 frivolous question is, and this, this surprises me, this means nothing, but do you realize that
00:03:36.660 the most prominent atheists are all Aries, right? So you're an Aries, I'm an Aries, Hitch was an Aries,
00:03:44.060 Dennett is an Aries, Matt Dillahunty is an Aries.
00:03:47.100 The great film director, Otto Preminger, was once approached by a starlet on, on the set of one
00:03:54.400 of his films. She said, oh gee, Mr. Preminger, what sign are you? And he said, I am a do not
00:04:00.060 disturb sign. That's my attitude towards astrology.
00:04:04.000 Right. Well, I guess Aries don't believe in astrology. So the first question, which I think
00:04:10.560 was, will set us on a nice path, it won't preempt everything else, but this is somebody
00:04:16.300 who clearly is exasperated with the prospect that we might focus exclusively on atheism or
00:04:22.060 bashing religion. And he says, for goodness sake, get him talking in detail about the genes-eye view
00:04:29.160 of natural selection, the extended phenotype, the argument surrounding group selection, and
00:04:34.800 punctuated equilibrium, the way memetics has rather ironically taken on a life of its own,
00:04:40.780 and so on. Not just God, for God's sake.
00:04:43.960 So this covers a lot of ground, and I do want to do those topics justice. So let's, I think people
00:04:52.400 are so casually aware of the revolution that has been wrought in our thinking based on our
00:05:01.200 understanding of Darwinism, and it was really crystallized in your book, The Selfish Gene.
00:05:07.680 But it has kind of receded into the background of our thinking, and it is such a strange view of
00:05:14.900 the mechanics of things and the logic of things. And so maybe let's just spend a little time talking
00:05:20.560 about the nature of replication.
00:05:22.480 I mean, I like to think if it has receded into the background, that's because it's simply accepted,
00:05:26.560 which among professional biologists of the sort of field type, it has.
00:05:32.120 Yeah, I'm thinking the general public that has kind of lost sight of how strange it is.
00:05:36.040 Perhaps the general public. It's not, well, I suppose it is a bit strange, and it sort of is a
00:05:42.640 turning on its head of the, what used to be the more orthodox view. Darwin saw natural selection
00:05:50.740 at the level of the individual. So he thought of individuals as competing with each other
00:05:56.260 within the species. It was always a within-species competition. And he was, of course, aware that
00:06:03.060 survival is only a means to the end of reproduction. And his other great book, well, one of his other
00:06:10.540 great books, The Descent of Man, is largely about sexual selections. And Darwin was thoroughly aware
00:06:15.280 that success at reproduction was also vitally important. And any hereditary tendency to be,
00:06:22.000 for example, sexually attractive or good at competing with members of your own sex would also
00:06:27.240 be favored. But Darwin didn't have gene language. He had no concept of the particulate gene, which Mendel
00:06:36.060 introduced. And that particulate view of genetics was actually essential to natural selection. Because,
00:06:47.220 as was pointed out in Darwin's own time, if genetics was blending, as everybody in the 19th century,
00:06:54.700 except Mendel thought, if we were all a kind of mixture of our father and our mother, then variation
00:07:02.440 would disappear as the generations went by. Each generation would be more uniform than the previous
00:07:07.580 one, in which case there would be no variation left for natural selection to work on. This was actually
00:07:12.880 advanced as an argument against natural selection. Actually, of course, it's an argument against
00:07:18.300 manifest facts, because we don't get more alike as the generations go by. Mendel solved that problem,
00:07:25.280 but Darwin didn't realize it. I don't think Mendel realized it properly. And it wasn't until the
00:07:32.780 neo-Darwinian synthesis of the 1930s that it was realized that actually a natural selection is all about
00:07:38.480 genes changing their frequency. So some genes become more frequent in the population, others less
00:07:43.460 frequent in the population. That's what it's all about. I suppose all that I did really was to take
00:07:48.420 that neo-Darwinian view and put it in a more, slightly more poetic way, and say that that means
00:07:57.120 that the individual is just a vehicle for carrying genes around and passing them on. And it's temporary.
00:08:04.880 I called it a throwaway survival machine. That's the strange idea where you call it strange. And
00:08:11.180 that is a bit strange, I suppose, that I call them a robot survival machine. An individual organism
00:08:17.260 is a device for passing on genes. The selfish gene is quite largely about not selfishness. It's often
00:08:25.020 misunderstood because of the title as being about selfishness or even an advocacy of selfishness.
00:08:30.600 It's actually mostly about altruism. The selfish gene explains altruism at the individual level.
00:08:39.480 Right. But if you take a genes-eye view of human life, many strange things happen. First, you
00:08:46.820 see that there's a logic by which certain genes would have been selected for and the behaviors they would
00:08:52.600 they would encode would be grandfathered into the human condition. And yet, evolution can't see
00:09:01.160 most of what we care about. The logic of evolution is anything that has allowed these specific
00:09:07.980 replicators to perpetuate themselves has been selected for, right? So we are here to spawn and
00:09:15.220 to ensure that our progeny successfully spawn. And I don't know, I mean, what age do you think
00:09:21.980 historically evolution ceases to care about us? I guess grandparents are still valuable.
00:09:28.880 Oh, there's no sudden cutoff. I mean, it's a gradual process. But the older an animal is,
00:09:37.220 the more likely it is already to have reproduced.
00:09:39.860 Right.
00:09:40.780 And so we're all descended from ancestors, most of whom reproduced when they were relatively young.
00:09:45.560 Yeah.
00:09:45.940 A few of whom may have been reproduced when they were old. And this, of course, is why we age,
00:09:51.080 because we're descended from young ancestors. And very often, whatever it took to be successful
00:09:59.180 when you were young made you actually more likely to die. And this is especially true, of course,
00:10:05.280 sexual selection, where brilliantly colored male birds, say, are more likely to propagate genes for
00:10:12.640 being brilliantly colored, but then dying, because brilliant colors attract predators just as much
00:10:19.240 as they attract females. And that's an extreme case, but that's the sort of model for the Darwinian
00:10:25.960 theory of aging.
00:10:28.620 Right, right. So, but there's still something about the extended family that would have been
00:10:34.700 selected. I mean, you would think grandparents are good for something.
00:10:36.840 Oh, yes. Oh, yes.
00:10:37.400 In helping ensure that.
00:10:38.540 That's right. And in those species where grandparents can, well, there may be a kind of
00:10:44.820 changeover point where when you get to a certain age, you can do your genes more good by caring for
00:10:51.720 grandchildren than you can by having more children. That, again, wouldn't be a sudden cutoff point,
00:10:58.540 but that probably is true of humans and a number of other species, perhaps.
00:11:04.920 But if we're talking about running viable governments and societies into democracies,
00:11:12.680 capitalism, pursuing scientific interests, building technology that doesn't destroy us,
00:11:18.800 these are things that obviously are parasitic on cognitive traits that have been evolved,
00:11:26.540 but evolution can't really see these details.
00:11:30.360 No, that's right. I mean, I think that so much of our human life has gone beyond natural selection.
00:11:37.440 Natural selection put us in the world in the way that we are, and our brains and our bodies are
00:11:42.500 designed by natural selection to survive under wild conditions in Africa. And we've now moved beyond
00:11:51.040 that. And so what we think of as successful in our society has really sort of pretty much left
00:11:58.800 natural selection behind.
00:12:01.020 Yes, not to put too fine a point on it, but this is an observation that several of us have made in
00:12:06.500 various contexts. If you were going to take a rigorously genes-eye view of the human circumstance,
00:12:12.500 certainly as a man, the thing you would want to do most, the thing that you would find most
00:12:18.120 fulfilling in life, the thing to which you would purpose more or less every day, is to donate
00:12:25.280 your sperm to a sperm bank so that you could have tens of thousands of children for whom you have no
00:12:31.280 financial or resource responsibility.
00:12:33.460 The fact that sperm donors are actually paid is thoroughly un-Darwinian and is a wonderful
00:12:40.660 example of how far we have actually advanced. It's not that surprising because natural selection
00:12:47.720 cannot build into our brains a kind of cognitive awareness of what our genes, so to speak, would
00:12:54.580 want. All it can do is build in rules of thumb which would work under natural conditions. And so
00:13:02.200 a desire for sex makes perfect sense because that, for the whole of history, the whole of, I mean,
00:13:10.260 evolutionary history, has tended to lead to reproduction. But a desire to donate your sperm
00:13:16.400 is something quite different.
00:13:17.820 It's not-
00:13:18.260 It can not foresee that technology.
00:13:19.660 It's not- Natural selection can't see that.
00:13:21.820 Yeah.
00:13:22.820 I mean, there have been a few notorious cases of doctors who have been substituting their
00:13:27.880 own sperm for donors and things like that. But it is, to a naive Darwinian, it is a surprising
00:13:34.960 fact that sperm donors have to be paid. A naive Darwinian would think that they would pay to
00:13:40.300 donate their sperm.
00:13:41.100 Right. Yeah. And pay quite a lot.
00:13:43.160 So let's just talk about what genes are for a moment. So genes are a kind of memory. They're
00:13:51.860 a kind of encoding of knowledge in the sense that, and stop me if you think at any point
00:13:59.680 these analogies break down, but I'm hearing echoes of David Deutsch here, where it's knowledge
00:14:06.040 as a kind of solution to a problem. It's a genetically inscribed solution to problems
00:14:15.460 that our ancestors have successfully faced.
00:14:17.940 Exactly. Yeah, exactly. I mean, I have a chapter in Unweaving the Rainbow called The Genetic
00:14:22.880 Book of the Dead, which sort of takes off from the, is it a Hindu classic?
00:14:27.240 The Tibetan Book of the Dead, yeah.
00:14:28.740 The Tibetan Book of the Dead. Sorry, Buddhist, yes. So The Genetic Book of the Dead, I see the
00:14:34.820 genome. Well, let's say the genes of a species as a coded document describing ancestral worlds
00:14:44.140 in which ancestors survived. That's sort of true because they are a filtered subset of genes
00:14:53.280 which have helped ancestors to survive. And in principle, it should be possible at some
00:15:00.200 future date for when technology has advanced, for a knowledgeable geneticist to read the genome
00:15:06.240 of an individual and actually read off a description of the worlds in which the ancestors
00:15:13.980 of that animal lived. Right.
00:15:17.520 Sure. To a lesser extent, I think perhaps it's easier, you can read the body of the animal. I mean,
00:15:22.920 I like to think that if you took a whole lot of water-dwelling animals, say mammals, so it would be
00:15:30.440 otters, seals, whales, water shrews, marsupials, swimming animals and things, they'd all have webbed feet,
00:15:39.780 say for example, except whales. And so that's an obvious one. But if you actually made a list of
00:15:45.380 characteristics of water-dwelling mammals and compared it with, say, desert-dwelling mammals,
00:15:50.800 you'd find a whole lot of things that all the water-dwelling ones have in common, including probably
00:15:56.640 some biochemical ones, some genetic ones. And so that's part of the description. The genetic book
00:16:02.700 of the dead describes water or describes desert. Right. And one day, maybe I'll even write a book
00:16:10.460 called The Genetic Book of the Dead, trying to flesh out this idea. Yeah. And of course, it could
00:16:16.840 also look forward prospectively to situations which we, now to take the human case, are not
00:16:25.140 well adapted to figure out. That's right. I mean, the genetic book of the dead has always got to be
00:16:29.540 a description of the past. And it helps the animal to survive to the extent that the future resembles
00:16:35.420 the past. Yeah. Which, on the whole, it does. I mean, if the world were totally capricious, such that
00:16:42.060 you could not predict the future on the basis of the past, then natural selection wouldn't work. But
00:16:48.520 nature doesn't vary capriciously as the years go by. On the whole, tomorrow is pretty similar to
00:16:55.960 yesterday. Actually, there was a specific question that touches on that point,
00:16:59.540 that someone asks, why do we need vaccinations or acquired immunity to diseases at all? Why can't
00:17:06.180 the mother pass on her immunity to her offspring? Wouldn't that be an enormous evolutionary benefit?
00:17:11.340 So we have acquired immunity because they're on the assumption that the environment does
00:17:14.840 change enough that that's the best algorithm to run.
00:17:18.960 Yes. I suppose the immune system is a kind of short-term, moment-to-moment substitute for natural
00:17:26.240 selection. Natural selection works over generations and equips the animal to deal with circumstances
00:17:32.740 that arise perennially, or at least over a long period. The immune system is all about equipping the
00:17:40.160 animal, adapting the animal to insults that attack it during its own lifetime from moment to moment.
00:17:46.740 There are always new epidemics, always new viruses cropping up. So that's what the immune system is
00:17:52.900 about. And vaccination is, of course, sort of preparing the immune system.
00:17:58.420 There's a gaming of that, yeah. But it would seem good to be immune to everything that your
00:18:03.300 mother had encountered.
00:18:04.260 It would. I suppose we tend to be immune to everything that most of our ancestors have
00:18:10.820 encountered, but just our mother. We don't seem to have a mechanism for passing on the particular,
00:18:16.740 if the mother's had chicken pox, we don't inherit an immunity to chicken pox.
00:18:21.060 Yeah. One thing that's framing this part of the conversation for me is I watched your somewhat
00:18:28.820 stifling conversation with Brett Weinstein, who I greatly admire, who I've done many events with.
00:18:35.220 But he had a kind of axe to grind with you around, if not group selection, something he was
00:18:42.180 calling lineage selection. And more broadly speaking, a sense that evolutionary thinking
00:18:49.460 should cover many of the details of human life, like war-making, genocide, nationalism,
00:18:57.700 to a degree that you were disinclined to extend it. And also just this notion that
00:19:04.820 you know, religion should certainly be considered an extended phenotype.
00:19:08.900 Mimetics generally should be considered an extended phenotype. And I'm just wondering what the,
00:19:14.980 I mean, I can't do a good impersonation of Brett for this conversation, but I'm wondering just what
00:19:20.660 are your concerns there and what are the limitations in Darwinian thinking when we're
00:19:26.260 talking about high-level human social phenomenon and psychological phenomenon?
00:19:31.060 Well, first of all, I, I, I hugely admire Brett Weinstein's
00:19:35.300 stand at that ridiculous university that he used to be a member of.
00:19:40.020 Evergreen, yeah.
00:19:40.900 Evergreen, yes. I mean, he's a real hero standing up against that nonsense.
00:19:46.660 The extended phenotype, I think, is often misused. The idea of the extended phenotype is often misused.
00:19:54.820 And I think-
00:19:55.540 We should remind people what a phenotype is.
00:19:56.980 Yes, I should. A phenotype is that which the genes engineer in a body, which in a Darwinian sense
00:20:06.660 would help the genes to survive. So wings are part of the phenotype of genes that help the genes
00:20:13.700 survive and behavior patterns and crests and sharp talons and sharp teeth and things. So we normally
00:20:22.660 think of genes program bodies to develop phenotypes. Phenotypes help bodies to survive. And that helps
00:20:29.940 the genes that built them survive. That's the normal way it happens. And genes do it by the processes
00:20:35.140 of embryonic development, causing the body to develop the necessary phenotypes. The extended phenotype
00:20:42.980 is phenotype, which is outside the body in which the gene sits. And my classic examples of this are animal
00:20:49.620 artifacts, things like birds' nests, where the nest, especially a complicated nest like that of a
00:20:56.580 weaver bird, obviously an adaptation. I mean, it's just like an organ. It's beautifully shaped
00:21:02.500 for a particular purpose, beautifully shaped, for example, a long tubular nest to prevent snakes
00:21:07.300 getting in. That is a perfectly good phenotype, but it's not part of the body.
00:21:12.500 Yes, the genes are producing that nest.
00:21:14.100 The genes are producing that, and they're producing it. They're still doing it via embryology,
00:21:17.620 but the embryology then, as it were, reaches outside the body in the form of behavior,
00:21:23.860 in this case, nest-building behavior. But that's only of yet one more step in the embryonic chain
00:21:31.700 of causation. The embryonic chain of causation begins with DNA influencing proteins, and that
00:21:37.060 influences something else. It influences something else. Cell division, neuron production in the brain,
00:21:43.860 which has the eventual consequence of causing the bird to build a nest of a particular shape.
00:21:49.380 So there's just this chain of causation, starting with DNA protein and going through various
00:21:54.340 complicated steps in embryology. And then the final steps are outside the body. That's why I call it
00:22:00.420 the extended phenotype. Well, then the idea is generalized to, for example...
00:22:05.380 I just want to pause here. At the risk of derailing you, I want to pause here to close the door to a
00:22:13.060 certain species of doubt that evolution can explain the diversity of life that we see. So now I'm just
00:22:20.340 closing the door to the creationists and the intelligent designers for the moment. Because
00:22:24.180 one of the concerns is that when you take any example of phenotype, you take a bat's wing, for instance,
00:22:31.780 evolution could not have produced a bat's wing de novo, you know, a bifunctional bat's wing. What
00:22:39.060 you need is some incremental path from no wing at all to a bat's wing. And each increment has to
00:22:46.900 survive the logic of evolution. It has to be useful and lead to differential success. So you have to
00:22:53.300 imagine here to explain any speciation and any path by which we have reached the diversity of life that
00:23:01.860 we see. You have to explain how each increment, the first little bump that became the wing, how that in
00:23:09.700 itself was useful. And many people just throw up their hands there and say, well, there's clearly no way
00:23:14.740 you can do that. So there must be some other explanation. Yes, thank you for reminding people of
00:23:19.140 that. I mean, that is, of course, very important. And of course, evolution has to take whatever is
00:23:24.580 there and modify it. So it's not like a little bump that appears. In this case, it's an already
00:23:29.620 existing arm. In the case of insects, it probably was a little bump because that's not using an existing
00:23:36.420 limb. But yes, you're, of course, right about that. With a bat, it's literally the hand.
00:23:40.900 Yeah. And as a membrane stretched between the fingers, which is not difficult to engineer
00:23:45.380 embryologically, because in the embryo, there already is a membrane between the fingers. And
00:23:51.940 actually, it's carved away. There's a kind of sculpture process whereby the membrane is removed.
00:23:57.780 All that needed to happen in bats is that that sculpting process didn't happen in the membrane
00:24:03.220 state. And of course, the fingers get hugely long. Pterosaurs do it differently. They just have one big
00:24:09.140 finger. Right. And they stretch that between the legs. And birds do it differently again. But in
00:24:14.980 every case, it makes use of what's already there. It modifies what's already there, rather than starting
00:24:20.500 de novo, which is what a human engineer would do. We start with a clean design on the drawing board.
00:24:28.340 Yeah. But I was saying about the extended phenotype.
00:24:30.820 But actually, before we get there, so what is the argument that some non-functional precursor wing
00:24:40.260 would nevertheless have been useful enough?
00:24:42.260 Yes. I mean, this is a favorite problem. What's the use of half a wing? There are a large number of
00:24:48.740 animals that don't exactly fly, but slightly increase their, there's, for example, arboreal animals,
00:24:58.420 squirrels say, who leap from branch to branch. And it's a dangerous process leaping from branch to
00:25:04.980 branch. And so any slight increase in flight surfaces, not really flight surfaces, but any
00:25:10.660 slight increase in the surface area that's presented to the air will increase the distance that a
00:25:16.020 squirrel can leap. The tail, the fluffy tail of a squirrel, acts as a sort of rudimentary aerofoil
00:25:23.940 that increases the distance that a squirrel can jump to. Well, now flying squirrels, they're just
00:25:28.500 squirrels, but they have a membrane between the forelimb and the hind limb, which started out,
00:25:36.260 no doubt, as just a bit of membrane in the armpit. It just slightly increased the, you know,
00:25:41.540 it could just leap one foot further because of that. And then when that was there, then next generation,
00:25:47.140 perhaps the next 10 generations, it could leap 10 feet further. So you have a steady gradient of
00:25:56.020 improvement. Are there orthogonal gradients that could explain some of these intermediate
00:26:01.220 forms like heat regulation or something? Well, that's been suggested for insects, yes.
00:26:06.420 It's been suggested that in the insect, they really did start by just bumps growing out of the thorax,
00:26:12.580 rather than modifying existing limbs. And it has been suggested that originally these were
00:26:20.100 thermoregulatory or were solar panels. And then when they got out to a certain size
00:26:28.260 for their thermoregulatory function, then they then happened to act as aerofoils. And so they then
00:26:36.740 became wings. And insect wings are moved, not by limbs, as I said, but by movements of the thorax.
00:26:44.820 So the thorax is, there are muscles in the thorax that contract it in various ways, which cause these
00:26:51.540 flaps to go up and down. Interestingly, some insects flap their wings up and down with a separate neural
00:27:00.900 command from the central nervous system saying up, down, up, down, up, down. But other insects
00:27:07.140 have a kind of motor, sort of oscillating motor, where all that the central nervous system says is
00:27:13.140 switch on or switch off. And the motor itself does a rhythmic up, down, up, down, up, down, up, down.
00:27:20.260 And the frequency of the oscillation is determined not by the central nervous system, but just by the
00:27:27.780 harmonic properties of the motor system.
00:27:31.860 Yeah. Okay, so back to the extended phenotype.
00:27:34.980 Yeah, well, the next step, after the idea of artifacts, after the idea of birds' nests, say,
00:27:42.180 there are many cases where parasites manipulate their hosts to increase the chance that they will
00:27:49.620 be propagated to the next stage of the parasitic cycle. So flukes, for example,
00:27:56.100 usually have an intermediate host, which might be a snail or it might be an ant. And they need to
00:28:02.900 get into their definitive host, which might be a sheep or a cow. And so in the case of the so-called
00:28:08.820 brain worm in the ant, for example, the worm in the ant burrows into the brain of the ant and changes
00:28:17.140 the behavior of the ant to make the ant more likely to be eaten by a sheep. It crawls up to the top of
00:28:24.900 stems in the heat of the day rather than going down into the ground. So the parasite is a kind of puppet
00:28:31.620 master, which is manipulating the ant to get, well, now that to me is an extended phenotype
00:28:39.460 because genes in the worm
00:28:42.340 have their phenotypic effect in ant behavior.
00:28:47.060 Yeah. I think there isn't there some evidence that toxoplasmosis and some other organisms
00:28:53.620 operate in mammals like ourselves and very likely in people in similar ways?
00:28:57.780 Well, to make us more likely to pass it on.
00:29:01.460 Yeah, modifying behavior.
00:29:03.620 I mean, rabies is the classic example. The rabies virus actually makes rabid dog, for example,
00:29:10.980 more likely to bite and froth at the mouth and pass on the virus when it bites. It also makes
00:29:19.220 the animal more likely to roam and wander far and wide rather than stick around at home,
00:29:25.060 which then spreads the virus more widely. So that's extended phenotype of a parasite.
00:29:32.180 And then you can say, well, parasites don't always live inside their hosts. Cuckoos manipulate their hosts.
00:29:38.580 A cuckoo nestling.
00:29:40.980 Yeah. Terrible bird.
00:29:42.420 Yeah. Terrible bird. Manipulates the host with beautiful adaptations. I mean,
00:29:47.220 supernormal gape and things like that. This is, again, manipulating the host behavior. The change in
00:29:54.820 the host behavior is an extended phenotype of cuckoo genes. Genes that change host behavior are more
00:30:01.780 likely to survive. Again, it works via cuckoo embryology. But the final stage in that change
00:30:08.500 of events in cuckoo embryology is to produce behavior which seduces the host, the reed warbler,
00:30:16.180 whatever it is. And so that, again, is extended phenotype. And then the next final stage in my
00:30:22.420 argument would be all birdsong, all animal communication, where one animal manipulates
00:30:28.980 another, you can think of as extended phenotypes. So a gene that changes in one animal has an
00:30:36.660 extended phenotypic effect on another animal via a call, a song, a crest, a flash, a conspicuous
00:30:45.380 signal. So my whole vision of animal signaling is a great network of extended phenotypes.
00:30:52.980 Right. Okay. So before we talk about the prospect of something like religion or any
00:30:59.140 other doctrine or institution being an extended phenotype for humankind, let's briefly talk about
00:31:07.860 this other species of replicator, the meme, which is a term of your coinage, which has an
00:31:13.540 importantly different connotation now that we've all spent our lives on social media.
00:31:18.580 That's right. But these are also, it's not, it's actually a decent analogy to the meme.
00:31:23.620 Yes. I mean, I wanted to make the point that what matters is replication. And genes are consummate
00:31:32.580 replicators and they achieve their replication success by manipulating bodies via the processes
00:31:38.500 of embryology. But I wanted to make the point that any replicator could do that. It doesn't have to be
00:31:43.460 DNA. And of course, on other planets, it almost certainly isn't DNA if there is life on other
00:31:48.260 planets, which there probably is. But then I said, well, maybe we don't have to go to other planets
00:31:52.580 because maybe memes, maybe cultural replicators could be the basis of Darwinian selection.
00:32:01.700 There certainly are cultural replicators, no doubt about that. I mean, things spread.
00:32:05.460 Does it matter that they don't randomly vary? The mutation isn't random?
00:32:09.780 I don't think that matters, no. I mean, it incidentally happens to be true that genetic
00:32:13.940 mutation is random. But even that is only random in the sense that it's not guided towards improvement.
00:32:21.220 But mutation is not random in other senses. Mutations are induced by cosmic rays, for example.
00:32:27.140 That's non-random. But mutation is random in the sense that it's not...
00:32:31.780 What do you mean it's non-random if it comes from cosmic ray bombardment?
00:32:35.460 Well, it has a cause. It's predictable that if you subject yourself to...
00:32:40.980 But the specific base pair that's being targeted is random, presumably.
00:32:45.620 That's true. Yes, that's true. But what's more important is that it's
00:32:49.380 random with respect to improvement. So there's no tendency for mutation to be, as it were,
00:32:55.780 anticipating what's necessary for survival. It is random in that sense. And the great majority of
00:33:01.140 mutations are actually deleterious.
00:33:02.820 Yes. Okay. So when we talk about memes, right? So now a meme is almost any cultural product,
00:33:10.180 an idea... That is replicated.
00:33:12.180 Yeah, that's replicated.
00:33:14.180 So it could be a clothes fashion or something like that, or a speech mannerism.
00:33:19.620 Right.
00:33:20.340 I mean, awesome is a...
00:33:24.820 Which I use with disconcerting frequency.
00:33:26.820 Do you? I never use it. I've given up. I mean, it's such a wonderful word to mean
00:33:30.900 what it really does mean.
00:33:31.860 Right.
00:33:32.420 Now it just means kind of okay.
00:33:34.580 No, I'm part of the slide into degradation.
00:33:36.980 Yes. Well, language evolves.
00:33:38.980 We have to accept that.
00:33:39.700 I am an American.
00:33:40.580 Yeah, yeah.
00:33:40.980 This would be predictable.
00:33:41.860 I mean, no, it's a good case, because language does evolve, and so we have to accept that.
00:33:47.060 Yeah. And I think there probably is some randomness, and not to say cosmic ray bombardment,
00:33:53.300 that accounts for the changes in speech patterns. But most memes, it seems to me,
00:33:59.940 the changes in them are engineered, at least with some forward thought...
00:34:03.220 That doesn't matter, actually.
00:34:05.060 No, so yeah.
00:34:06.180 It doesn't really matter. I mean, natural selection would still work, even if mutation,
00:34:11.620 genetic mutation was engineered. And of course it can be.
00:34:13.940 Yeah.
00:34:14.420 We are now in a position to do that.
00:34:16.020 Right.
00:34:16.660 So that's what genetic engineering is.
00:34:18.500 Right.
00:34:18.900 Which we'll talk about. So the fact that the basis for the change, directed or not,
00:34:26.260 you still have an environment where things are competing, and there's differential success,
00:34:32.820 and so the environment is providing a kind of selection mechanism.
00:34:36.340 Exactly, yes.
00:34:37.380 So memes, ideas, ways of doing things, really all of human culture and ideology,
00:34:44.980 this is being continually produced and spread and going in and out of fashion.
00:34:51.140 And so this is this domain of memetics, and there literally are what are now called,
00:34:56.260 you know, memes on the internet, you know, graphics paired with text that spread on social media,
00:35:01.540 that spread various ideas. I don't know, how do you feel about that appropriation?
00:35:07.140 I'm not particularly keen on that appropriation because they are a very specific example of a meme.
00:35:12.660 Of a meme, yeah.
00:35:13.220 I would rather think about whether natural selection of a sort actually guides the spread of memes.
00:35:23.220 And I like the idea of a meme complex or memeplex where something like a religion, like Roman Catholicism,
00:35:34.820 could be regarded as a meme complex.
00:35:36.900 Right.
00:35:37.380 And individual memes might be the idea of life after death or the idea that you have to confess your sins or something like that.
00:35:44.660 The virgin birth, yeah.
00:35:45.540 Virgin birth. And just like gene complexes are sets of genes which flourish in each other's presence.
00:35:55.140 Right.
00:35:55.460 And that, I think, is an extremely important idea in genetic evolution.
00:36:01.060 So there might be something similar in meme complexes.
00:36:04.340 Yeah, so there's a common fate to these various genes and various memes.
00:36:09.140 Yes, yes.
00:36:09.460 They're all hitched together, yeah.
00:36:11.140 That's right. And so I like to think of, say, the gene complex of a carnivore species like leopards,
00:36:21.300 where you have carnivorous teeth, carnivorous eyes, carnivorous brains, carnivorous limbs.
00:36:26.980 They all go together. And on the other hand, you have antelope, I mean, the herbivore prey,
00:36:33.380 eyes, noses, limbs, etc., which go together. If you suddenly plonked an antelope gene into a leopard gene pool,
00:36:43.540 it probably wouldn't work. It wouldn't cooperate well with the other genes of the leopard gene complex.
00:36:51.540 It would be a very skittish leopard.
00:36:53.620 Yes, yes, yes, yes.
00:36:55.940 The cowardly leopard.
00:36:56.820 The cowardly leopard. And so a species is a collection of mutually compatible genes,
00:37:03.620 which go well together, as opposed to another species, which is complex of different genes.
00:37:09.300 Well, I believe you might do the same kind of thing with meme complexes,
00:37:13.540 but the theory hasn't been really sort of worked out.
00:37:16.900 Right.
00:37:17.540 I think it might be.
00:37:19.300 Okay. So we have meme complexes, something like Roman Catholicism. And what was being urged
00:37:28.260 upon you in your conversation with Brett, and I've seen this come up many times before,
00:37:33.380 is that something like Roman Catholicism should be, or religion in general,
00:37:38.580 should be considered part of the extended phenotype of human beings.
00:37:43.940 I've never liked that. I've never liked, I think that's taking the idea of the extended phenotype
00:37:49.540 beyond where it should be. And I think it detracts from people's ability to comprehend the idea of
00:37:56.100 the extended phenotype. Extended phenotype is supposed to be a genetic effect, which manifests itself
00:38:02.340 outside the body in the same kind of ways, genetic effect manifests itself inside the body. And people
00:38:08.980 have some, I don't think Brett does this, but people have sometimes said to me,
00:38:12.260 isn't a building like the building we're in at the moment, an extended phenotype.
00:38:18.020 And I think that would only be true if, say, there were genes that caused architects
00:38:23.940 to design a different kind of building. And there aren't. I mean, there's no gene that makes an
00:38:31.540 architect more likely to make Gothic arches rather than Romanesque arches.
00:38:36.180 So our mere survival dependence on buildings is not enough to have it?
00:38:42.660 No, I don't think so, because variation in buildings is not under genetic control.
00:38:47.060 Right.
00:38:48.260 And I doubt very much that variation in religious habits is under genetic control. If it was,
00:38:56.580 then you might make some sort of a case for talking about extended phenotype. But it's not like that.
00:39:03.140 And so I think that it's possible to push an idea too far. And I think that's what's going on here.
00:39:09.300 Yeah. So what about the prospect that having religions led to differential success of various
00:39:19.540 groups of human beings?
00:39:20.820 Well, that's quite a different idea. And that's worth considering in its own right. And also,
00:39:24.900 it's what's worth considering in its own right is the idea that individuals having religions might
00:39:30.180 survive better. That's been suggested and might be true. This opens the door to what's been called
00:39:36.420 group selection.
00:39:37.140 Yes. And I've never been a fan of group selection. Darwin himself was, it wasn't called group selection
00:39:44.580 then. Darwin almost always was talking about individuals surviving better within a species. But
00:39:52.180 Darwin did, again in The Descent of Man, in one passage, talk about a kind of group selection,
00:39:59.780 where he suggested that groups of humans who had some kind of social cohesion, who behaved well
00:40:10.100 towards each other, had altruism toward each other, cooperation, would be more likely to survive
00:40:14.900 than groups that didn't. And so that would be a form of group selection, I suppose.
00:40:21.780 In some ways, I prefer to compare that not to group selection, but to species competition.
00:40:29.620 A bit like when the gray squirrel was introduced from America into Britain as a sort of frivolous
00:40:37.700 exercise.
00:40:38.180 Wait, we did that to you? Was that a good idea or a bad idea?
00:40:40.260 Terrible idea.
00:40:41.700 And it drove the red squirrel extinct.
00:40:44.340 And so I think that would be a better analogy for a group that, say, has a
00:40:51.780 has a warlike aggressive god like Yahweh or like some of the Norse gods. You could make a case that
00:40:58.500 having a militaristic god, maybe one who rewards martyrs in a martyr's heaven, that kind of
00:41:07.780 religion might spread as a kind of group effect, as a kind of species effect, an ecological
00:41:12.900 competition effect. But I would call that ecological competition rather than group selection, I think.
00:41:19.620 Well, yeah, because it's, so let's just create an example. Let's say that Hitler won
00:41:29.140 the Second World War and we are now living under the Thousand Year Reich and everyone who's not a Nazi is
00:41:34.740 now dead. So Nazism would have triumphed over all competing political ideologies so that we,
00:41:44.660 on some level you can say, well, this is a selective effect, right? This is, there were
00:41:49.780 various competitors for political ways of thinking and one has finally dominated and
00:41:55.460 cancelled all others. But that doesn't seem to suggest an analogy to the replication model.
00:42:03.140 I don't think it does. No, I don't think it does. I mean, slightly closer would be if, say,
00:42:07.860 within any country, individuals who espouse Nazi beliefs were more likely to survive than individuals
00:42:15.140 who didn't. So there would be an individual differential survival effect, which probably would
00:42:20.020 also have been the case. That would be a closer analogy to Darwinian selection and we might do a
00:42:26.660 kind of mimetic analysis of that. Nazi memes survive better than anti-Nazi memes, for example. That would
00:42:32.980 be the case of mimetics. Yeah, I think that might actually be the environment we're currently in on
00:42:38.180 social media. I can forbear to comment on that. Sorry, I guess one final question here. So are there
00:42:47.140 outstanding questions in what is now called the neo-Darwinian picture that are significant
00:42:57.380 challenges to the model? I mean, there are many people, and Brett, you know, frankly, is one of
00:43:02.020 these people. There are many people speaking as though neo-Darwinism, and perhaps you should actually
00:43:08.020 define that term, is basically flawed in a way that should be troubling to biologists and public
00:43:15.540 intellectuals. Yes, I don't think that. I mean, any flourishing science will change, of course.
00:43:21.780 And Steve Gould was fond of saying that the modern synthesis is effectively dead. And I thought that
00:43:29.380 was a rather irritating attempt at almost self-publicity. Well, he was irritating in many
00:43:37.540 ways, as it turns out. Okay, yes. But what is your, so first define neo-Darwinism. Well, okay,
00:43:44.820 neo-Darwinism is the, the neo-Darwinian synthesis was a joint effort in the 1930s, really, of,
00:43:54.660 I think, above all, R.A. Fisher, J.B.S. Haldane, Sewell Wright, Ernst Meyer,
00:44:00.900 Theodosius Dobzhansky, G.G. Simpson, and others. And it was,
00:44:07.700 seeing Darwinian evolution as changes in gene frequency in populations. That was the population
00:44:15.380 genetic part of it. Seeing, well, the paleontological part of it would be
00:44:21.540 seeing major macro evolutionary change as micro evolution writ large. So the geneticists
00:44:30.420 were showing how from generation to generation you could get slight changes in gene frequency. And
00:44:37.540 paleontologists like Simpson was showing that such micro evolutionary changes
00:44:44.820 extrapolated over millions of years, tens, hundreds of millions of years, could produce changes from,
00:44:50.900 from fish to mammal. So the, the, this, this movement of the 1930s and 40s, we're still in it.
00:44:58.900 It, it hasn't really changed much. There've been, I suppose, W.D. Hamilton with his analysis of
00:45:06.900 altruism, kin-selected altruism is one major
00:45:11.220 advance of the 1960s and 70s. But, but we're still in the neo-Darwinian era.
00:45:16.180 And you don't think there are gaping holes in the theory that, that should keep people?
00:45:21.220 No, I don't. I mean, there are, there are questions that remain to be answered. One of
00:45:24.980 the big riddles is the evolution of sex, you know, what, what, what, what sex is good for.
00:45:30.580 And lots of the most distinguished neo-Darwinian theorists have grappled, grappled with that
00:45:37.140 problem. The origin of the Darwinian process is, is still a bit of a mystery. How, how did the first
00:45:43.460 replicator arise? And was it, it almost certainly wasn't DNA actually. I mean, the first replicator
00:45:48.820 would have been something else.
00:45:49.860 Would have been RNA?
00:45:51.220 Maybe. That, that's a good possibility. And that's one of the more fashionable ideas, but
00:45:56.260 that is still in the realm of theory. It may never become
00:46:00.020 settled because it's happened a long time ago and maybe
00:46:03.780 impossible to, to repeat exactly what happened. We know the kind of thing, it must have been,
00:46:09.780 it was the origin of something self-replicating, possibly RNA.
00:46:14.020 And so what about epigenetics and the way in which they, this feature of our biology seems to
00:46:22.740 suggest a, almost a quasi Lamarckian kind of an inheritance?
00:46:26.420 Yes. This is a strange word epigenetics, because actually,
00:46:30.500 originally it was just another word for the way we see embryology. I mean,
00:46:34.900 every, every cell in, in the mitotic, every mitotic reproducing cell in the body has the same genes.
00:46:41.940 Right. So your, your liver cell has all the genes that your brain cells have.
00:46:46.340 That's right. Yes. And, and different genes get, get, get turned on. And so the, the epigenetic
00:46:52.980 environment of a, of a gene in the, in, in, in a brain cell is different from that in a, in a,
00:46:57.380 in a liver cell. And, and so that's epigenetics. The, the word has been hijacked fashionably recently
00:47:05.700 by people with, as you say, a kind of neo Lamarckian bent to suggest that some of that
00:47:11.940 epigenetic cytoplasmic environment, in which some genes are turned on and others are not,
00:47:18.900 can get inherited to the next generation. And that does seem to happen in some cases.
00:47:25.620 So examples like the stress experienced by the mother with the infant in utero.
00:47:33.060 Yes. Yes.
00:47:33.940 The, the, the, the change in hormonal environment there, it can actually create some durable effect
00:47:38.660 on the, the expression of, of genes in the baby.
00:47:41.460 Yes. That, that, that does seem to be, that there are a few rare cases like that. I, I don't think it's
00:47:48.500 worth the attention that it's been given. I, I prefer to reserve the word epigenetics for the ordinary
00:47:55.620 process of embryology and say, just occasionally there may be epigenetic effects, which do pass
00:48:02.100 on to the next generation, maybe even to the grandchild generation, but it's not one of these
00:48:06.020 things that goes on forever, like true genetic mutation.
00:48:09.300 So what, what is the current frontier of evolutionary biology? If you'd like to continue listening to
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