In this episode, Dr. Peter McCulloch joins me to talk about the Chalice Study, a preprint published in The Lancet on August 10, 2019, and a recent study from the Oxford Division of Public Health in Vietnam showing that during a lockdown in a hospital, workers were infected with the SARS Delta Variant and passed on the virus to one another. Dr. McCulloch and I discuss the implications of that study, as well as other recent data on SARS and SARS-related infections, and how vaccines are failing to stop the spread of SARS across the population. We also discuss the recent announcement by the FDA that they will be reviewing a new SARS vaccine from Pfizer, the Sarcoid. We also talk about a new vaccine from AstraZeneca that could prevent heart attacks and strokes in patients with SARS. This episode is sponsored by VaynerSpeakers, a leading global provider of high-performance SARS vaccines and treatment centers. Please consider pledging a small monthly fee to help support our efforts to keep this podcast on the cutting edge of science and medicine. Thank you so much to everyone who has contributed to this podcast and is willing to share their knowledge and support our mission to inform the public about the importance of this important topic. We can't wait to hear back from you! - Caitlin Durante, MD, MPH, PhD, MS, MSU, MSSE, MAJOR, MAO, B.C. (University of Kent, PA) and Dr. Andrew Werneth, MD (PhD, MAU, D.C., MAO (PhR, NY) ( ) ( ) ( ), Dr. James Eichner, PhD ( ) , Dr. J. ( ) & Dr. C.S. ( ), Sarah ( ), PhD ( ). Dr. David ( ) joins us to talk all things SARS ( ) and much more! . , , and , ( ) . . . ( , J.E. ( ) ( . ) ( ), & ( ), and ( ) - Dr. S. ( . ) ( ( , ) & ( ) ? ( ). ( ) is a fellow? , , , & ) , . ) , . . ( ) AND ( ) ... ), ( ] ... ( ) )
00:00:00.000Hey everybody, I have one of my heroes on today, Dr.
00:00:03.000Peter McCulloch, and I want to ask you, you had an article that ran in The Defender yesterday, and it was an article about the Chalice Study, which was published, it was a preprint published in the Lancet on, I think it was on August 10th.
00:00:19.000Can you tell us about, you know, what the implications are of that study?
00:00:24.000Well, as we are really in the midst of this Delta outbreak, which is occurring worldwide, particularly in countries that have higher proportions of the population vaccinated, we are asking the question, how in the world can we have so many vaccinated individuals but yet had such a prominent outbreak of the Delta variant among vaccinated and unvaccinated?
00:00:48.000And this paper from Chow, from a unit of the Oxford Division of Public Health that's in Ho Chi Minh City in Vietnam, has demonstrated that during a lockdown, so in June, they had an outbreak and they locked down the hospital where the workers could not get out of the hospital.
00:01:03.000And then they were assiduously checking the workers and testing them for SARS-CoV-2, as well as doing sequencing.
00:01:10.000They indeed found workers that were contracting COVID-19 within the lockdown period, a total of 69.
00:01:18.000They ascertained that from not only the Delta variant, but additional mutations, in a sense, the fingerprint of the exact strains that the workers were passing it to one another.
00:01:29.000And then the big finding was their calculation of viral load.
00:01:34.000And this group had actually calculated viral load from oral and nasal secretions in the past.
00:01:39.000The viral load was 251 times that of the previous unvaccinated era, where they had used the So they had previous workers and patients who had had COVID-19 before any exposure to the vaccines and now the vaccinated were carrying a massive viral load and in fact passing it to one another.
00:02:01.000So the The mystery is that vaccinated individuals are carrying a higher viral load.
00:02:22.000Experts, vaccine experts, immunologists that had suggested this because we knew originally that the vaccines were non-sterilizing.
00:02:30.000That is, the vaccines could not get the immune system to completely eradicate the virus early in the early studies.
00:02:37.000And so the fear was that we're going to create, in a sense, super spreaders.
00:02:42.000And what we found was the vaccine is actually clearing the way so that they can walk around asymptomatic and that they can have these huge viral loads in their nasal pharynx that they are blasting out to the community, to patients, to anybody that they meet.
00:03:02.000Well, you know, I'm not sure they're asymptomatic.
00:03:04.000In that paper, they used the word pre-symptomatic since they did evolve symptoms.
00:03:08.000So it's just that they were doing very assiduous testing.
00:03:11.000So, you know, I don't think we should start really going after the vaccinated with asymptomatic testing, but the message here is...
00:03:18.000Is the vaccinated clearly are susceptible to COVID-19 and the Delta variant.
00:03:22.000The vaccines in this case, in this example, it was the AstraZeneca adenoviral vaccine, but we know separately from Israel that exclusively uses the Pfizer vaccine that the Israeli health minister now has the Pfizer vaccine down to 17% vaccine efficacy.
00:03:39.000The Mayo Clinic has Pfizer using Rochester, Minnesota inhabitants vaccinated with Pfizer They have Pfizer down to 42% efficacy.
00:03:48.000And these levels are far below the 50% regulatory standard to even have a vaccine on the market.
00:03:54.000So it's clear that whether it's Delta, whether it's AstraZeneca or Pfizer in these working examples, the vaccines are failing.
00:04:01.000Now, I want to point out one other really shocking data point that came out this week.
00:04:07.000You and I talked about earlier that the six-month Pfizer clinical trial study has just come out, and it shows that there is no All cause mortality benefit from the vaccine.
00:04:24.000In other words, the people in the placebo group, there were, I think, 20 deaths in the vaccine group and only 14 deaths in the placebo group.
00:04:33.000And what the study showed is that the vaccine actually prevents people, small numbers of people, from dying from COVID. But for every person that does not die from COVID because of the vaccine, Three extra people are dying from heart attacks.
00:04:52.000So there's actually a negative mortality benefit from the vaccine.
00:04:57.000And, you know, between that study and the Chow study, it doesn't seem to make any sense that we just, that the FDA yesterday, just approved the vaccine for licensing, and it didn't have any public process.
00:05:14.000It didn't bring in The VRPAC committee to consult, which is unprecedented.
00:05:21.000They just hammered this through in order to allow the mandates.
00:05:25.000I guess to unpack that, there's actually a lot to unpack.
00:05:30.000Even the six-month data are, in a sense, an extension of a previous era of COVID-19.
00:05:36.000So during the time of the randomized trials, we had a blend of variants.
00:05:41.000And the dominant variant that we had, it wasn't dominant, but it was always 20 or 30 percent We're good to go.
00:06:03.000And since it's such a tight, tight timeframe, the idea that myocardial infarction that may have actually been related to the prothrombotic effect of the vaccine is very feasible that it would actually negate it under those circumstances.
00:06:17.000Now, in the 13-page document that's available publicly on the FDA website now, I've had a chance to review it.
00:06:28.000It's looking at vaccine efficacy over 90% from the original registrational trials, which were very short with the older strains.
00:06:36.000There's no contemporary data with Delta.
00:06:39.000And throughout the entire letter, it mentions emergency use authorization, including the final paragraph.
00:06:45.000It looks like an extension of the emergency use authorization.
00:06:48.000There's no proposed package label or product insert.
00:06:51.000There's no important safety information, and there's no briefing booklet.
00:06:55.000So it's far from a standard of what's available today that anybody would look at for full approval.
00:07:01.000It looks like an extension of the EUA that's publicly available today.
00:07:05.000I know it's the first day of release, but we'll have a careful look at the package insert.
00:07:09.000And if it doesn't have contemporary data, With respect to the Delta variant, which is now nearly 100% in the United States, it may be immediately obsolete.
00:07:19.000I'll just explain this to the audience.
00:07:22.000Basically, you have a vaccine that may have been effective in the beginning.
00:07:27.000It may have been 90% effective, according to what they're saying, although there's problems with those numbers as well.
00:07:35.000But today, with the Delta variant, it is less than 50% at best.
00:07:41.000And normally you cannot get a vaccine approval if it's less than 50% effective.
00:07:51.000One is this idea of it must be at least have 50% vaccine efficacy, or in a sense that's interpreted as kind of a theoretical 50% protection.
00:08:00.000And then another reasonable standard is that it ought at least last a year in terms of having a durability of a year.
00:08:08.000A lot of our Vaccines last, you know, 10 years like a tetanus booster or, you know, many years, 5, 10 or more years for hepatitis B. But to have a vaccine that already there is a call for boosters, in fact, they're being done right now at six months of duration, eight months of duration, and the boosters are not adjusted for the variants.
00:08:29.000So we know that Delta is considerably mutated spike protein, and that's the only thing We're good to go.
00:08:47.000That's produced by human cells after the vaccine is injected.
00:08:52.000So it doesn't matter how many boosters one give, if it's missing the target, it's going to be futile.
00:08:58.000And in fact, ever since the booster program has been started, which is just a few weeks ago in Israel, there's already failures among those who've received a third shot.
00:09:07.000Yeah, you know, I... Recall that there was, during the last year before COVID, there were a number of studies that came out on the measles vaccine.
00:09:19.000And those studies show that you get some benefit from the second booster, but essentially zero benefit from the third booster.
00:09:27.000So even with measles, which is pretty stable, In terms of the mutation rate, the third booster provides almost no additional efficacy.
00:09:38.000And here they're basically giving you a booster that is obsolete.
00:09:44.000It doesn't even address the microbe that you're trying to kill.
00:09:49.000I think the hope is to try to overwhelm it with very high levels of antibodies.
00:09:55.000And we know that with the vaccines, the titers...
00:09:59.000Of the antibodies with the vaccine are far higher than that with the natural immunity, but those are antibodies directed against the spike protein.
00:10:07.000With the natural immunity, we have a full library of IgA since the respiratory illness starts in the nose and the mouth.
00:10:13.000Then we have libraries of IgG against not only the spike protein in the natural infection, but also the nucleocapsid and many other antigens.
00:10:20.000So we may have hundreds, if not thousands, of antibodies in full T cell helper, T killer cell.
00:10:27.000So the natural immunity is robust, complete, and durable.
00:10:30.000And the vaccine immunity is, in a sense, an overshoot on a very narrow library of antibodies directed against the spike protein.
00:10:37.000And so what's happening is this antigenic escape and trying to keep boosting the antibodies.
00:10:42.000In a recent paper from Israel, where the first author is named Dr.
00:10:47.000Israel, in that paper, they showed that month by month, the antibodies after the vaccination Drop by 40%.
00:10:56.000So they're very high, but they drop, drop, drop, drop.
00:10:59.000And then by six months, the natural immunity antibodies, which is only part of the great immunity of natural immunity, exceeds that of the vaccine immunity.
00:11:07.000So one of the things that's not supportable is any claim that vaccine immunity is better than natural immunity.
00:11:15.000Natural immunity is robust, complete, and durable.
00:11:18.000And to my knowledge, there's never been a bona fide second case of COVID-19.
00:11:22.000When I mean second case, I mean somebody's sick with the characteristic signs and symptoms and proven PCR antigen and sequencing to actually prove that they have a second infection.
00:11:31.000It's never been reported, to my knowledge.
00:11:34.000You and I talked last night, I was asking you, if you were in Tony Fauci's position, what would you have done differently at the beginning of this pandemic?
00:11:44.000I'm clearly not involved at all in terms of giving advice on the pandemic response, but if I was, if I was in that position, I would have immediately had teams of doctors assembled with a focus on sick individuals and doctors who had ideas and started to get early experience on treated patients with COVID-19.
00:12:06.000And you can work in groups of four, six, and eight doctors that should have been meeting around the clock Finding out the best ways to treat Americans.
00:12:14.000And we should have focused on one endpoint, and that's the composite of hospitalization and death.
00:12:20.000The goal would have been to reduce hospitalizations and death and make this a manageable problem at home.
00:12:26.000And then worry about everything else after that, but handle the sick individuals.
00:12:31.000I would have had international collaboration and would have had very frequent updates because this pandemic was moving around the world and still is.
00:12:51.000We should have had a budget to invest in large-scale, outpatient, short clinical trials with the goal of reducing hospitalization and death.
00:13:01.000This would have been extraordinarily helpful.
00:13:04.000It would have saved hundreds of thousands of lives in the United States, millions of lives outside of the United States.
00:13:09.000And I think those clinical trials relatively quickly would have arrived on the fact that single drugs weren't going to work, that we needed drugs to be used in combination to reduce viral replication, cytokine storm, and thrombosis.
00:13:22.000So it would have been early treatment, early treatment, early treatment, and that would have kept the hospitals unloaded.
00:13:28.000We would have had the investment that we had in hospitalized care, but it would have been in a continuum with outpatient care.
00:13:35.000So all these big medical centers that were fielding these admissions to the hospital should have had treatment clinics.
00:13:43.000It could have been outside field tents.
00:13:45.000They could have done this in order to really kind of meter out how many hospitalizations would have been happening.
00:13:53.000So focus on early treatment, having enough resources in the hospital, then I would have worried about everything else.
00:13:59.000This idea of how does the virus spread and hand sanitizers and masks, that can all be secondary to just handling the sick people And then having a vaccine strategy could have been considered and could have been thought out, but it should have been done, in my view, in a much more careful manner.
00:14:15.000It clearly should have used established and safe vaccine technologies and not, out of the box, use a brand new mechanism of action to try to put mass vaccination in the population.
00:14:26.000I know you just came from your hospital moments ago.
00:14:30.000What are you seeing now in the hospital in terms of vaccine injury and COVID injury and death?
00:14:36.000Well, let's take COVID as we see it now.
00:14:39.000So clearly the Delta variant is predominant.
00:14:42.000The Delta variant is said to be less fatal and less virulent according to the UK variant report.
00:14:50.000I think the August 6th, the 20th version, still has the mortality overall for Delta far less than 1%.
00:14:56.000So it's actually fourfold less than the Alpha variant or the UK variant in their data.
00:15:01.000But these are people who are sick enough to go to the hospital in the UK and My clinical experience, and I have dozens of patients right now.
00:15:08.000My clinical experience at Delta may be somewhat easier to treat as an outpatient, but I have to tell you, when patients are hospitalized, I have a great respect for this infection that, in fact, I've had fatalities in younger individuals, which is really alarming.
00:15:23.000Each and every fatality and each and every hospitalization that I'm aware of has not received adequate early treatment.
00:15:35.000We have 500,000 pre-purchased doses and our agencies and our major medical centers are not telling the public Where these antibodies are, how they can access them, who qualifies, how can someone get a course of monoclonal antibodies?
00:16:19.000Well, the vaccine adverse event reporting system is only source right now.
00:16:25.000Our US FDA and the CDC, which are the joint sponsors of the public vaccine program, which is an investigation, you know, they have no critical event committee.
00:16:34.000They have no data safety monitoring board.
00:16:37.000This is an abrogation of standards of safety for participants in human clinical investigation.
00:16:44.000It's the only time that I'm aware of that we haven't seen the Office of Human Research Protection's OHRP step in on this.
00:16:51.000We should have had a data safety monitoring board with the size of this program doing monthly reviews of safety and giving advice to the program on whether or not it should continue or whether there should be modifications in the program.
00:17:05.000There was no data safety monitoring board involved.
00:17:09.000And looking backwards, we had a mortality signal with this program at 27 million Americans vaccinated on January 22nd.
00:17:16.000The mortality was 186 patients and that would exceed a confidence above a usual expected for the entire class of injections at 150 deaths.
00:17:25.000So at January 22nd, if we would have had a day safety monitoring board review the data, the DSMB would have shut this down in February, and they would have had to look at the deaths and say, where are they happening?
00:17:36.000Are they happening in COVID recovered patients who shouldn't be receiving the vaccine?
00:17:40.000Are they happening in the frail elderly?
00:17:43.000And shockingly, We're in August, and our vaccine program sponsors, the FDA and the CDC, have yet to have a single press briefing or a single report on comprehensive safety.
00:17:53.000All we have is the self-queried VAERS report, and the VAERS report takes temporary VAERS cases, and then when they're ascertained as being permanent VAERS numbers, that means the CDC has verified the event happens, it goes into the database and comes up on a weekly open frame Open data source that anybody can click called Open VAERS and we are at now 13,000 deaths that the CDC has told us has happened.
00:18:23.000Over 200,000 emergency room visits, clinic visits, and we have separate external analysis.
00:18:29.000We shouldn't have to rely on this, but we have them because there's such a great need to understand by McLaughlin and colleagues from London that have shown that 50% of these deaths occur within two days of getting the vaccine.
00:18:44.000Most are seniors in their 70s or 80s who die, and 86% of the time, there's no other explanation.
00:18:50.000Someone healthy enough to walk into a vaccine center Separately, we know that from an extrapolation from the Center for Medicaid and Medicare Services, which they do know who's been vaccinated and they do know when someone has died, has corroborated this and in fact has extended the estimate that the numbers who have died are probably closer to 45,000 after a vaccine.
00:19:11.000I told you about 186 who should have been our tolerance for this, for the whole program, for the whole year.
00:19:16.000So this is off the rails in terms of mortality, absolutely off the rails.
00:19:20.000And I just had a patient in my practice.
00:19:25.000Two weeks later, she was admitted for a diffuse, really dangerous prothrombotic syndrome where she had micro blood clots in both her arteries and legs.
00:19:33.000She was in the local hospital here in Dallas, Fort Worth, for a week.
00:19:36.000She received intravenous anticoagulants, went home on aspirin, no additional anticoagulants.
00:19:41.000When I saw her, she had very poor pulses in her legs.
00:19:44.000She had evidence of nerve damage in her arms and her legs.
00:19:52.000I found blood clots up and down her blood vessels in her legs.
00:19:56.000I put her on even stronger blood thinners.
00:19:58.000And today I was notified by the Dallas coroner's office that she was dead.
00:20:02.000And I want to see the death certificate.
00:20:04.000I told the coroner's office I want to take a look at this because I can tell you her background case is that she simply had some mild emphysema that was treatable She was 64 and she shouldn't have lost her life after a vaccine.
00:20:33.000And did she say that the doctors were responding in an appropriate way?
00:20:39.000She was admitted to an outside hospital initially, and I could not get a clear understanding if her event was reported to the CDC or if it wasn't.
00:20:51.000So I went ahead and did the reporting, and it looks like my report was the first.
00:20:55.000So this first event that she landed in the hospital, no one took the effort to report it.
00:21:01.000You know, one would actually have to get the vaccine card, which I needed, and have the lot numbers And carefully go through this and I have to enter in all my medical information, who I am, my office location, the original hospital location.
00:21:12.000It took me about a half an hour to do the entry.
00:21:15.000And I'm telling you the total number of these entries that have been certified by the CDC now of Americans is astonishingly 545,000.
00:21:25.000545,000 times doctors took an effort to the level that I did to enter in a vaccine injury or now a vaccine-related death.
00:21:34.000So I have to go back in now and update the CDC that, in fact, she's died.
00:21:41.000The total number across 70 vaccines on the U.S. market, about 278 million shots, the total number of reports that go into the system per year are about 16,000.
00:21:52.000We're at 545,000 with the COVID-19 vaccine program alone.
00:21:57.000You know, you made a remark earlier that I didn't understand.
00:22:00.000You said that there was like an action level at 186 vaccines where they should have reviewed it, but there's no mandatory level at which point they pull a product, right?
00:22:13.000In this program, there appeared to be, there's no statistical analysis plan.
00:22:18.000There appeared to be absolutely no safety plan whatsoever, but I'm saying a properly designed program would have had a data safety monitoring board.
00:22:26.000They would have had periodic reviews based on accrual of data.
00:22:30.000And I can tell you that when the number of deaths would have exceeded a confidence limit where it was clear that it was now rising above a level Of which one could be confident that it's not the same as expected.
00:22:44.000If we have 150 deaths with 278 million shots in the United States, and they're not temporarily related to the vaccine, they get reported at different times, and now suddenly we're faced with 186 at 27 million shots with the COVID-19 vaccine.
00:23:01.000Any high quality day safety monitor board, and I tell you, I'm in this business.
00:23:27.000Well, on two occasions, the CDC has very casually put out on their website, one in March and one in June, they've put out a statement that the CDC doctors and FDA doctors have reviewed all the deaths and none of them are related to the vaccine.
00:23:46.000That includes these immediate deaths that occur in the vaccine center where the vaccine personnel are doing CPR, for instance.
00:23:53.000They concluded, and I tell you, at that point, when that first statement came out in March, I have to tell you, for me, that was probably the turning point for me.
00:24:02.000I was already behind on the mortality signal.
00:24:05.000That January 22nd landmark, I missed it clinically.
00:24:14.000It's the hardest thing for Americans to swallow this, but that's malfeasance.
00:24:18.000That's wrongdoing by those in position of authority.
00:24:22.000The FDA and the CDC in no way could have reviewed 1600 deaths.
00:24:28.000That takes forever to get all the hospital records, the death certificates, to review everything, to carefully look at when the vaccine was given, to have two separate reviewers They have to review it for causality.
00:24:41.000They have to make a causality assessment.
00:24:43.000When they disagree, there has to be a third adjudicator.
00:25:07.000We do it in every single clinical trial.
00:25:09.000In fact, the experts were involved in the original registrational trials.
00:25:14.000So the standards that were conducted when used for the registrational trials for all three manufacturers suddenly are thrown out, and now there's absolutely no safety paid attention to the public program.
00:25:27.000You know, in October of 2020, there's a slide set that was produced by the CDC, and they had all kinds of plans for monitoring safety during the public program.
00:25:37.000They were going to use a whole variety of databases.
00:25:40.000They were going to be checking things and quickly reviewing safety events as they occurred.
00:25:49.000Americans had absolutely no protection on safety during this program.
00:25:53.000It's a complete lapse of the regulatory standards for clinical investigation.
00:25:58.000Do you think it's possible that the vaccines are killing more people than would have died from COVID or causing more death and injury than they are averting?
00:26:34.000So I can tell you if we started de novo and we didn't have a legacy of deaths due to COVID-19, we started de novo and go forward, I think it's very likely the vaccine is actually causing more injury than the respiratory virus itself.
00:26:49.000Peter McCulloch, I'm going to let you go.
00:26:50.000I know you're in a rush and you're exhausted.
00:26:53.000Your incredible work taking care of these patients, trying to save American lives, and trying to demand integrity from our government officials.