Big Pharma's war on peptides is a symptom of a disease, not a cause. And to understand the disease, we have to go back in history to see how Big Pharma got to where it is today. And the disease is private industry and its influence on the federal government, and the decisions they make. And it's a disease that's spread throughout all of the government and it's spread through every facet of our government, including the military industrial complex. And we're here to break it all down. Today, we're taking a deep dive into the history of Big Pharma's role in our healthcare system, and how they've gotten to where they are today, and what they've done to get us to where we are today. We're going to take a look at how they got there, and why it's so important to understand what's going on in the world of pharmaceuticals and the role Big Pharma plays in our health care system, as well as how they influence our government and our elected officials. And we'll talk about the real cause of this disease, which is Big Pharma and the influence they have on our government. Joe Rogan's The Joe Rogans Experience, by day, by night, all day, and by night by night all day by night. All day long, by Joe's perspective on life and liberty and the meaning of liberty and freedom and freedom. Today's episode is a mashup of two different perspectives on what's happening in our world and how we should be thinking about the world and what we can do to improve our lives and the way we should we should think about our health and our lives. I hope you enjoy it, and that we can learn from it, because it's going to have a better day, not have it, so we can be better, better, and have a more informed, more informed day to day life. -Joe Rogan - Joe's Note: This episode was originally published in the New York Times on Nov. 7, 2019. . It's a good one, so make sure to check it out and tweet me what you think of it! and let me know what you thought of it on Instapreneurspace in the comments section if you have any thoughts or feedback you'd like it, we'll be listening to it. Tweet me on Insta: or share it on your feed!
00:02:14.000There was a small little company that reached out to the Third Reich and said, Literally,
00:02:33.000within six months, there's letters back to the Third Reich from this pharmaceutical company saying, Thank you so much for your cooperation.
00:02:42.000The women arrived in great health and working order.
00:02:46.000Unfortunately, none of them made it through the initial phases of our trial.
00:03:30.000So jump forward to Eisenhower's speech, his famous speech about the military industrial complex.
00:03:38.000What a lot of people don't realize is there was a second half to that speech where Eisenhower warned the American people about the medical industrial complex.
00:03:47.000He warned that if we allow private industry to control, monopolize, and profiteer Off of health and healthcare, that they will silo innovation, stifle innovation, and capitalize and monetize innovation.
00:04:04.000And I would argue that's 100% what we've seen.
00:04:10.000And the reason I want to walk the public through this is because to understand what's going on, you've got to see the history of how it's happened.
00:04:17.000So, now you jump forward to the 80s, okay?
00:04:21.000Time and time again, when Big Pharma has had an opportunity to choose left or right, over and over again, they have chose profits over patient outcomes.
00:04:38.000They inadvertently contaminate thousands of specimens with HIV. They know that they've contaminated specimens with HIV, this drug with HIV virus.
00:05:14.000Division of the pharmaceutical company Bayer sold millions of dollars of blood clotting medicine for hemophiliacs, medicine that carried a high risk of transmitting AIDS to Asia and Latin America in the mid-1980s while selling a new, safer product in the West, according to documents obtained by the New York Times.
00:05:33.000And two, everything I referenced, Jamie, because this was something last time, I am going to mention a lot of controversial stuff, so I've listed reference after reference after reference on the Ways to Well website.
00:05:44.000Anything that I reference will be on there as well.
00:05:48.000So jump forward, they infect all these people with HIV. Okay, in the 80s, compounding pharmacies and specialty pharmacies and generic manufacturers attempted to create HIV treatment options that were affordable for third world countries.
00:06:04.000Because at the time, it was like $14,000 a month for an HIV treatment to keep you alive.
00:06:10.000Nobody could afford that in those countries.
00:06:14.000This big pharma in a market they can't sell, in a market they can't touch, in a market where they inadvertently infected, or I would say almost knowingly infected 20,000 people with HIV, they then lobby with the U.S. government, file and sue the shit out of all of these companies that were attempting to make cost-effective generics.
00:06:35.000It caught it up in litigation for three years before finally they bent to the will of the American people and the feedback of Of the public.
00:07:14.000And so how does the FDA come to these conclusions?
00:07:18.000It's because a majority of their funding comes from private industry, and a majority of their discussion, their talk track, their influence, their belief systems, and their thought processes are being influenced by these companies.
00:07:31.000So when we talk about peptides today in specific, there's over 7,000 peptides on the market, okay?
00:07:50.000These are short-chain amino acids found naturally in nature.
00:07:54.000They were patented for the dosage and delivery mechanism because you cannot patent a molecule.
00:08:01.000You can only patent the delivery mechanism and the dosage.
00:08:04.000And so the FDA allows all those peptides, but it's because Big Pharma is monetizing them and Big Pharma has their ear.
00:08:13.000And so we talked a little bit about this on the last podcast and I didn't dig as deep because we didn't have as much time.
00:08:20.000We just burned so much time covering all of this crap.
00:08:22.000But one of the things I saw is it goes beyond the FDA. This insidious virus that this disease state that we're seeing the symptoms of Carries all the way into the DEA, the DOJ. When I owned my own pharmacies and labs that build insurance,
00:08:42.000that was one of the things I was talking about.
00:08:44.000I hired a former Department of Justice prosecutor to come in and help me build out my compliance program.
00:08:51.000And he told me, Brigham, when I was at the DOJ, we had an open meeting every month with the heads of the pharmacy benefit managers, where they would come with stacks of papers, books of papers of people that they wanted us to federally indict.
00:09:23.000You have a, let's say I build a blood lab, which I did, and I go out and I educate clinicians on the importance of running comprehensive blood work.
00:09:32.000I go to the insurance companies and I say, I would like to be in network with you, United, Cigna, Aetna.
00:09:40.000We're not taking any more in-network contracts.
00:09:43.000So my options at that point are to lay everyone off, shut down, and go home, or bill them out of network.
00:09:51.000The issue with billing them out of network, and so the patients understand, or the listeners, You're paying for out of network benefits and you're paying these big companies, these big insurance companies for the right to be able to choose where you get your blood work done,
00:10:08.000your blood work analysis, all of these things.
00:10:11.000What ends up happening is if you're out of network as a lab, as any of these, whether it's a blood lab, a genetic screening lab, like Gary talked about the MTFHR test, the motherfucker test.
00:10:24.000We were doing that eight, nine years ago.
00:10:27.000That was one of the tests we offered was this gene carrier test to identify the root cause of why people are having these issues.
00:10:34.000Any of it, insurance said, no, we're not going to let you in network.
00:10:38.000So you're forced to bill out of network.
00:10:55.000Now what the insurance companies do is they wait till I've billed them millions and millions of dollars and Then they go sit down at a desk with the Department of Justice and they say, look at this.
00:11:07.000This motherfucker billed us $1,000 a test on a test that should have been $350, right?
00:11:13.000And I'm not blaming the Department of Justice.
00:11:14.000They are acting upon the information that they are given, right?
00:11:18.000They are being fed bad information by bad players, and that leads to bad decisions.
00:11:24.000And at that point, if they bring forth a case on somebody, you're done.
00:11:59.000And so this is what I explained again on RFK was, but if you didn't do anything wrong, you have nothing to worry about.
00:12:07.000When I started this, the head of the DOJ who I hired to help me with compliance, he told me, there's two things that will get you in trouble with the Department of Justice.
00:13:47.000And then once you're on their radar, you don't get to present your half of the case.
00:13:52.000So to get an indictment, all it takes is a prosecutor presenting to a jury of your peers, which in the state of Texas has an eighth grade literacy level.
00:14:02.000And they say, hey, these guys billed, you know, United $5 million last year on lab tests that United say should have been, you know, $800,000.
00:14:13.000Do you think there's enough info to dig deeper?
00:15:42.000And so peptides are short-chain amino acids.
00:15:45.000And the only reason I go down the path of the DOJ stuff is to just give the public the awareness of it's beyond the FDA. It's in all branches of the government.
00:15:56.000And Bad info in equals bad decisions out.
00:16:02.000If you look at it from a different lens, I go, okay, when I try to sit in the seat of an FDA decision maker, I look at it and say, to play devil's advocate, you know, it's one of two things.
00:16:38.000They reclassified the peptides under a category of dangerous.
00:16:42.000And through that, they indirectly have killed the market on those peptides because most doctors in America are not going to write a drug that's on an FDA dangerous list because it opens them up to litigation and risk.
00:16:55.000And how do they classify something as dangerous?
00:16:59.000Don't they have to have some kind of evidence?
00:17:02.000In this instance, there's no evidence.
00:17:05.000And even if you look at adverse events that have been reported across the United States, almost all those adverse events are black market.
00:17:11.000Any adverse event regarding BPC-157 is literally a black market product that somebody bought from China or Canada that's filled with potential particulates or...
00:17:27.000issues of contamination or lack of efficacy or too much efficacy and so where I was going with this is if you we know for sure that the peptide itself isn't dangerous so then you go and say okay Do you not think that FDA-regulated compounding pharmacies are capable of compounding these peptides?
00:17:49.000The highest paid person in my building is my quality and compliance guy.
00:17:55.000He literally worked for Abbott Laboratories for 15 years, working hand-in-hand with the FDA to make sure they follow all of their protocols and procedures.
00:18:09.000Any product that comes into our pharmacy at Revive, our compounding pharmacy, we make sure it's an FDA-approved ingredient with an independent third-party verification of the ingredient itself, showing that it is 100% the ingredients they tell us it is.
00:18:27.000Then we compound it in an ISO 5 environment.
00:18:31.000The law says we need to do ISO 7. We go above and beyond and use an ISO 5 sterile facility.
00:18:38.000We have the two highest paid employees in our building are our regulatory compliance guys that are over quality controls.
00:18:46.000Okay, so then from there, whenever we compound a product, we send every single batch off to be independently third-party verified by an independent lab, unaffiliated with us, and we file those records away.
00:19:14.000So it's either one, you're saying the peptides dangerous or two, you're saying compounding pharmacies are incapable of compounding drugs that aren't dangerous.
00:19:23.000And if that's the case, then why are you asking us to compound hundreds of drugs that are on FDA backorder lists?
00:19:31.000Because your buddies at Big Pharma aren't going to compound them.
00:19:55.000So I just go back to, I have to believe that you're acting upon bad information.
00:20:01.000And I want to give them the benefit of the doubt.
00:20:04.000And, you know, my message is we've got to go meet with the FDA and we've got to start having conversations and we've got to represent...
00:20:10.000Small compounding pharmacies and the average American because right now they're only hearing half the story and that half of the story is big pharma banging on the desk and saying, hey, we want to patent these peptides.
00:20:24.000We're going to go through clinical trials.
00:20:26.000We're going to do it the right way, you know, and we're going to do all these checks and balances.
00:20:31.000But it's like we don't need you involved in supplements.
00:20:35.000Like if you really look at it, I mean, again, I've said it.
00:22:23.000When we compound these medications to meet the needs of the people who can't get those medications or maybe can't afford those medications because they're on a FDA backorder list and they're asking us to compound them.
00:22:35.000Big Pharma then turns around and sues compounding pharmacies throughout the country, then uses their long reach of PR firms to put it in the news, make it sound like you don't know what you're doing, like these compounding pharmacies are dangerous, they're not regulated,
00:22:52.000it's the wild west out there in compounding pharmacies, there's no oversight, these aren't FDA approved products.
00:23:48.000Because Eli Lilly specifically, with its product, got one of their facilities shut down because they failed FDA inspection with egregious actions.
00:23:58.000We saw just a few weeks ago, eye drops that are from FDA approved sources got recalled.
00:24:06.000And when a whistleblower blew the whistle, they go in and there's people in their isosterole rooms barefoot.
00:24:13.000Like, the level of egregiousness and manipulation is insane.
00:24:18.000But when you control the media and you have the ear of the government and you can move chess pieces, it makes it hard to, you know, be able to navigate that, compete with that, and educate people.
00:24:29.000And so, if you didn't give me a platform, nobody would know this stuff.
00:24:34.000If it wasn't for people like you and Robert Kennedy and people who question things and challenge the system, I can't SEO optimize.
00:24:43.000I can't Google search engine optimize.
00:25:01.000Well, a lot of their advertising and funding comes from Big Pharma, and so it makes it tough.
00:25:08.000Well, we found that out during the pandemic.
00:25:10.000But what's fascinating is it's had a terrible effect on their bottom line.
00:25:15.000Because people watch them shill for these pharmaceutical drug companies and not report adverse events and not report the dangers of shutting down schools and all the harm that it's doing to children, all the harm that it's doing to business, because they didn't report on that.
00:25:35.000CNN showed recently its lowest rating since 1991. Well, look at what they did with you with the vaccines.
00:25:43.000And I don't know if you saw now, two different articles in the last 60 days, probably.
00:25:49.000One is that people who have been vaccinated multiple times over, I think, the age of 60 are at an increased risk of being hospitalized with COVID was one of the articles.
00:25:59.000And then the other article was that two of the heads of the FDA that approved the vaccines now went to go work for Moderna.
00:26:09.000In the last 40 years, okay, the last 40 years of the FDA, two heads of the FDA have not gone to work for industry.
00:26:22.000And that's the same thing that was happening at the DOJ, and that's why I wanted to bring up the DOJ as well, even though they have nothing to do with the peptides, they are part of the healthcare industrial complex, inadvertently, because they're being used as an attack dog By the big insurance companies.
00:26:41.000And all it takes is one orthopedic surgeon getting indicted for something or one general surgeon getting indicted for something for everyone to go, fuck that.
00:26:54.000And now insurance doesn't even cover any of those tests.
00:26:57.000And so they're going to force anything out of the marketplace with time, but in the short term, they're going to run their offense.
00:27:03.000And that same level of spit that's being swapped at the FDA is being swapped at the DOJ. So the big insurance companies attempt to recruit away DOJ prosecutors, and once they've built their reputation in working as a steward for the people at the Department of Justice,
00:27:21.000and they put some big hides on the wall and big I don't think the average clinician in America even understands.
00:27:41.000When you have an insurance special investigative unit show up at your practice, which happens, so if you run a lot of blood tests, or you do a lot of genetic tests, or you do anything that the insurance company thinks, man, this guy's doing these tests.
00:27:54.000I don't want him doing these tests anymore.
00:28:45.000Like, when you go to a surgery center, there's a good chance that that surgeon owns into that surgery center.
00:28:51.000Okay, if you go to, if you have a clinician, like somebody from the mothership, they couldn't get, they could not get their GLP-1 semaglutide.
00:29:03.000So they reached out to me and said, hey, can you get my dad semaglutide?
00:29:07.000And I'm like, yeah, we make it at the pharmacy.
00:29:09.000The doctor wouldn't send to our pharmacy.
00:29:11.000And it's most likely because he had a relationship with another pharmacy, right?
00:29:15.000And so that physician may have been invested in that pharmacy.
00:29:19.000And as crazy as that sounds, the law says they can.
00:29:24.000As long as you don't pay them on the value or volume of their referral, they're allowed to have a passive interest.
00:29:29.000So think of it as you're investing in a stock, right?
00:29:32.000If I work at Abbott, I mean, if I'm a doctor and I prescribe a drug from Pfizer, I'm still allowed to invest in Pfizer stock.
00:29:39.000What I'm not allowed to do is receive direct remuneration In accordance with the value or volume of my referral.
00:29:47.000It cannot be an arrangement where you say, I'm going to give you $100 per patient.
00:29:54.000That's a violation of federal and state law.
00:29:57.000However, if there is a bona fide investment opportunity and 100 clinicians buy into a hospital and then they operate at that hospital, the law says they're allowed to own into that hospital and own up to 40% of that hospital.
00:30:12.000And so, Again, and two, I always like to give both sides of the story, and I said this on the last podcast.
00:30:18.000There are bad people doing bad things throughout every aspect of this.
00:30:24.000It's not insurance companies are all bad and clinicians are all good and lab owners are all good.
00:30:31.000There is egregious stuff happening at all levels.
00:30:35.000And there are indictments that the Department of Justice bring forth that are 100% justified.
00:31:12.000And most people have zero idea this is happening.
00:31:15.000Most people just look at the recommendations, whatever it is, whether it's been discussed in the media, whether their doctor tells them, and they don't have any idea what the influence behind that is.
00:31:29.000But the side effect profile's safe on the peptides.
00:31:33.000Like, there's the efficacy, like, time and time again.
00:31:36.000I cannot tell you how many people, how many patients and clinicians who buy BPC for their patients throughout the United States have had phenomenal results with the healing factors.
00:31:47.000And I attach some links on the Waste Well website about BPC and studies done with healing spine injuries, with healing joint injuries, and And there's even a study on safety, and it wasn't in humans, but the safety study was in mammals, dogs,
00:32:52.000Either the FDA will hopefully meet with compounding pharmacies and have the discussion and we can dive a little deeper and hopefully bring them to the light and bring awareness to this.
00:33:04.000Or they ban these things and what's going to happen is exactly what happened with the opioid pandemic.
00:33:10.000People are going to turn to black market.
00:33:13.000We had more opioid related deaths last year than ever in the history of the United States.
00:33:18.000More people have now died of opioids than the Vietnam War.
00:33:22.000It is killing young Americans left and right.
00:33:24.000It's because you allowed Purdue Pharma to push a product into the market that never had safety trials as far as addiction goes.
00:33:34.000They piggybacked onto a previous indication of their cotton system.
00:34:21.000Especially if you're getting it from some country and they're cutting corners and they're just selling you whatever they can.
00:34:26.000And so the fallacy though, the biggest fallacy is that if it comes from a big pharmaceutical company and it's in the American market, that it's safe.
00:34:37.000Because time and time again, they've misrepresented the safety, they've misrepresented the efficacy, and then you go beyond that, they've also misrepresented their compliance and regulatory and their quality controls.
00:34:52.000Where I was going earlier is they've outsourced 30% of their manufacturing to outside of the United States to third world countries where it's cheaper to manufacture.
00:35:03.000In fact, a lot of them are manufacturing in rural areas of India where sometimes there's no running water at the hotels.
00:35:11.000So if I'm an FDA inspector and I can choose to go down the street and inspect a compounding pharmacy in Austin, Texas, Or I've got to get on a plane and fly to a rural part of India and now I have to give you three months heads up before I come,
00:35:27.000When the FDA shows up at my building, they show up and they say, we're coming in and you're going to let us look at everything you're doing and we're going to follow your employees around for the next three weeks and we're going to see if anything they've done is incorrect.
00:36:24.000So when they're putting these things on the dangerous list, things like BPC-157, is the idea that they're going to come up with their own version of BPC-157 or something similar to it and patent it because they know the demand is there?
00:36:41.000That is my assumption, is that that's what Big Pharma is attempting to do, because I don't understand otherwise why the FDA all of a sudden would have made this choice.
00:38:12.000The reason that supplements aren't regulated by the FDA is because Ronald Reagan said, I don't want the FDA telling me what vitamins I can and can't take.
00:38:20.000But because this is an injectable and it's sterile for the most part, and there are pill forms too, but the FDA says, well, if it's an injectable, it's sterile, and it's made at a compounding pharmacy, then we have oversight.
00:38:32.000But I want to be clear, they didn't ban it.
00:38:36.000And this is one of the things that makes it difficult to navigate as an entrepreneur is you go, well, what are we supposed to do with that?
00:38:43.000Does that mean we're not allowed to make it?
00:38:45.000Does that mean we are allowed to make it?
00:38:46.000You're saying it's dangerous, but we're not having side effects and we're having great efficacious results.
00:39:19.000I stood in surgeries from dusk till dawn, watching products that have never had human safety trials go into the body, time and time again.
00:39:28.000When people think that going into an orthopedic surgery or going into a general surgery or going into an OBGYN surgery, you make the assumption that all these products have been through human safety studies and all this stuff.
00:39:40.000And I talked about this on our last podcast too, but...
00:39:43.000Over 90% of the products that are in the operating room never went through human safety studies.
00:39:50.000The FDA created what's called the 510K approval process in the 70s.
00:40:51.000Imagine Henry Ford's car versus Elon Musk's Cybertruck.
00:40:57.000That's the difference and it's moving at a breakneck speed and It's shocking that there's not more adverse events, but we also know that less than 2% of adverse events get reported.
00:41:11.000And so, I can give you a real-world example on that, too, when I was a rep.
00:41:41.000As the technology changed and the shaver handpieces got smaller and smaller, a lot of these companies didn't update their packaging inserts.
00:41:49.000And so they didn't update their sterile processing procedures.
00:41:52.000And so what happened is tissue began to gunk up in handpieces.
00:41:56.000And this was not unique to one company.
00:41:58.000I'm not going to say the company's names and I'm not going to name the hospitals.
00:42:20.000We've gunked up tissue from previous surgeries in that.
00:42:24.000And so when you take this product from one surgery to the next surgery to the next surgery, we know that certain bacterias are extremophiles.
00:42:32.000They can handle, so they auto-quave it.
00:43:13.000Like with stem cells, one of the big things that's happened is when they throw out adverse events, even with the stem cells or biologics products, almost all of those adverse events have nothing to do with the product and everything to do with the chain of command.
00:43:30.000So, look at how rigorous the chain of command is on me as a compounding pharmacy.
00:43:36.000I told you, step by step by step, check, balance, check, balance, check, balance.
00:44:15.000They're not following any of those protocols.
00:44:17.000And even the storage facilities that almost all of these implant companies are using and device companies, they're not paying for climate controlled storage typically.
00:44:27.000They're sticking them in a storage shed and then a month later that products going into surgery.
00:46:06.000And so I just say this because when they're throwing stones or people are like...
00:46:13.000Peptides are dangerous or stem cells are dangerous.
00:46:16.000This is nature and the rules and the regs and the restrictions and the safety nets and the protocols and the chain of custody and the hoops that we jump through.
00:46:28.000Whether we get a biologic, whether cellular or acellular.
00:46:32.000When it ships out, they say what time it shipped.
00:46:34.000It ships on dry ice, stored at frigid temperatures.
00:46:39.000When it arrives, we have to sign for it, and then we immediately unbox it and load it into a cryo-freezer and document each lot number, what time we put it in the freezer, and within 30 days, if we don't use that product, we discard it.
00:46:53.000Even though there's nothing that says it's not viable or it's not going to be as good, that's the protocol.
00:46:59.000Because we're going to go above and beyond and follow the most rigid safety protocols.
00:47:04.000And that does not happen in traditional medicine.
00:47:07.000The average American is assuming that if they go into surgery, that's safe.
00:47:12.000But these stem cells, man, who knows about that?
00:47:28.000It's just so corrupt that it feels helpless when you're discussing this.
00:47:33.000There's this feeling that the more you dive into this and the more you describe things, the deeper you expose the corruption, the more it's so confusing because it doesn't seem like there's a way out.
00:47:44.000Well, and you asked me last time, you were trying to ask me to articulate how I started Ways Dwell, how I started Revive.
00:47:51.000And we spent three fucking hours going through all this.
00:47:53.000The truth of the matter is, I saw a problem.
00:48:21.000Now I have to figure out how to make these products cost-effective enough to be able to sell them to the average American, the average Joe, you know, not the affluent.
00:48:30.000Everybody needs to be able to afford these treatments.
00:48:33.000So I built a 503A sterile pharmacy and we began to make products that were in the gaps.
00:48:40.000Anything I saw that insurance didn't cover, wouldn't cover, was egregiously price gouging patients on is what we would make at our compounding pharmacy.
00:49:20.000It took 75 years of dogma and confusion for testosterone to pull itself out of the doldrums of the dungeons to be utilized daily as a go-to resource for aging men.
00:49:33.000And the only reason testosterone made it out was because one guy had the balls to test it.
00:49:39.000No pun intended, but it was Dr. Morgan Tyler, a urologist, famous urologist, said, this was prior to Viagra, he said, I've got to do something for these guys who have erectile dysfunction.
00:49:59.000He began to analyze his patient population and see that it wasn't increasing prostate cancer in his patient population.
00:50:05.000So then he went back and did a retrospective study all the way back to the 1930s where we found out that the original study that created that dogma that maintained its status for over 75 fucking years was total bullshit.
00:50:29.000And now it's proven time and time again, if testosterone was increasing prostate cancer, we would have seen a huge spike in prostate cancer.
00:50:36.000What we're seeing is about 14% of men develop prostate cancer.
00:51:18.000What Morgan Tyler discovered was when we take you from 50, chemically castrated, to low, 250, We increase your risk of prostate cancer because your prostate cancer risk at zero testosterone is basically zero,
00:51:54.000You can only water a plant so much, right?
00:51:57.000Once that plant has water, it's not gonna absorb any more water.
00:52:01.000The prostate can only, the testosterone can only bind to a certain amount of receptors.
00:52:06.000Once those receptors are binded, then there's no continual upside risk.
00:52:11.000And then you get to get the benefits of testosterone that begin to reduce those risks of cancer.
00:52:16.000But today, in primary care, you will still have doctors Who quote a study that's been debunked a hundred times.
00:52:26.000And there's this dogma that exists over and over again in healthcare where it's like the data's there, the research is there, the info's there, but the system itself isn't allowing for it.
00:52:39.000And so when we look at that, I talked about this on the last, when we talk about insurance companies and pharmacy benefit managers, Every drug on the market that is covered by insurance is controlled by a pharmacy benefit manager.
00:52:54.000And those pharmacy benefit managers prioritize drugs and their classifications not based off efficacy, based off profits.
00:53:04.000And so they are monetizing those drugs through rebates with the big insurance companies.
00:54:20.000They're managing your medications, your treatment options, and they're monetizing your disease state.
00:54:27.000They make money on every step of the way.
00:54:32.000And since the last time we spoke, a new one came out, Ohio, the state of Ohio, they realized that over 200 pharmacies had gone out of business.
00:54:42.000The pharmacies were saying we're getting paid less and less, but yet the government was paying more and more.
00:54:53.000They used, I think, I can't remember, 30-something auditors at the state level, and what they found was $240 million in pharmacy benefit manager fraud.
00:55:10.000And money that they extrapolated from the American people, from the people of the state of Ohio, because taxpayer dollars are who's paying for this stuff.
00:55:17.000And these pharmacy benefit managers are making their money on the spread.
00:55:22.000So there's layer upon layer upon layer of how insurance companies can move dollars to maximize profits.
00:56:27.000They're doing their best to navigate a shit system.
00:56:30.000They write me an Ambien and an antidepressant or an anti-anxiety and they push me out the door.
00:56:36.000And that's their go-to treatment because that's the tool in their tool belt.
00:56:42.000The difference is, if somebody were to come in the door of Ways to Well, or any of these cash pay clinics, I don't even want to make it about Ways to Well, there are hundreds of phenomenal clinics across the country.
00:57:37.000Let's look at the other thing we would do.
00:57:39.000We would run an EEG to assess if you have insomnia, anxiety, depression, all of these things.
00:57:47.000Another way to dig into the root cause separate from biomarkers is an EEG. To run a brainwave test that tells us, is your brain neurons firing at the posterior of your brain to the prefrontal cortex of your brain?
00:58:00.000And if you're losing data from the posterior to the prefrontal cortex, what you find is people with depression, with anxiety, with all these things, they're losing 40 to 50% of that neuropathic firing from the rear of their brain to the front of their brain.
00:59:41.000Are you going to put your life in the hands of these fucking assholes that are here to extrapolate money from you and manage you into chronic disease?
01:00:38.000They're not gonna mess with it because they're just, again, trying to make it through the day.
01:00:41.000And so those were pathways to be able to educate a clinician and give them some insight into why they should be doing these tests clinically.
01:00:51.000But yeah, even today, if you talk about cellular therapies, if you talk about peptides, most primary care clinicians in this country have no idea about peptides.
01:01:17.000You and I were talking about infrared beds and red light therapy.
01:01:22.000It is viewed by a lot of the doctors in this healthcare system, and I say healthcare loosely, it's sick care, as pseudoscience, bullshit, chiropractic stuff.
01:01:39.000But if you look, infrared and these technologies, photo light therapy has been used since 1903, 1905. The guy won a Nobel Prize.
01:01:49.000Huberman does a two-hour breakdown on this stuff.
01:01:55.000There are over 60 studies that show infrared works.
01:01:58.000There was a study done in Europe that showed infrared improved vision in people over the age of 40. Like using three minutes of infrared, three days a week, returned vision and eyesight.
01:02:22.000Literally, when you're taking NAD drips and you're doing all this stuff, you're doing it to try and get your cells to produce more ATP. Because as we age, our production of ATP declines.
01:02:33.000And ATP is the energy source of a cell.
01:02:35.000And our eyes have a limited amount of ATP. But they require a massive amount of energy.
01:02:41.000And so as we age and our ATP declines, our cells are incapable of...
01:02:49.000Having the amount of energy required to maintain great eyesight.
01:02:53.000And so through infrared, through NAD treatments, through NMN, through all of these various modalities that are not being utilized in traditional medicine, you can make a difference.
01:03:49.000I'm not saying that this is going to cure MS. That's not at all.
01:03:53.000He has gotten better results and has felt better over the last eight months than he ever felt on that $14,000 a month medication.
01:04:03.000So, it's, for them to understand it, we've got, we would have, and that's why it's like, so to move, to be able to use these treatment modalities, you almost have to go cash pay.
01:04:13.000And then what I'm trying to figure out is, how do we bring this to the masses?
01:04:17.000How do we bring longevity-based, predictive, proactive, personalized medicine to the masses?
01:04:25.000How do we bring this precision approach to everybody?
01:04:28.000And that's where I think large language models are going to change the game.
01:04:52.000Part of being personalized goes above and beyond personalizing treatments with peptides and all these different things to personalizing the patient experience.
01:05:01.000Some people want to call their clinician at 2 a.m.
01:05:03.000I can't tell you how many days I wake up and somebody who went through the program messages me asking a clinical question and I've got to bug the clinician and I've got 30 of those, right?
01:05:13.000Or the clinician gets an inbox filled with questions.
01:05:16.000The future of medicine is large language models will manage all of that.
01:05:20.000Alan will be able to assess your medical record.
01:05:23.000He'll be able to read your MRI. He'll be able to read your DEXA. He'll be able to read your VO2 max.
01:05:28.000He'll be able to assess your all-cause mortality risk.
01:05:31.000He'll be able to tie into your wearables, tie into your REM sleep, monitor your heart rate variability.
01:05:39.000We're going to know what date you started testosterone, what date you started a peptide, what date we began to see improvement on all of your biomarkers.
01:05:46.000Or if we don't see improvement, we're going to know in advance that this isn't a good medicine for you.
01:05:58.000Can you explain when you're saying large language models, you're talking about artificial intelligence.
01:06:02.000Yeah, well, so the really smart guys like Lex would say, well, large language models are just assessing massive amounts of data and guessing the next word, right?
01:06:12.000And so ChatGPT is a large language model.
01:06:15.000They don't consider it AI. But isn't the speculation one of the reasons why they think Sam Altman was pushed out is that ChatGPT has acquired artificial general intelligence in the newest models?
01:06:30.000That is what I've heard from my AI guys as well.
01:06:35.000I was told that he has a fiduciary duty to the board to disclose if the ChatGPT makes a leap, is what they call it.
01:07:29.000And the AI guys were saying this is an example of like things that the large language model is kind of like improv-ing on its own that wouldn't be like a programmed behavior.
01:07:39.000So, I mean, the future is scary and exciting, right?
01:08:05.000Like everything, Alan and these AI models are a tool in the tool belt.
01:08:09.000And any tool can be used for good or for bad.
01:08:13.000And so my vision for the future of AI and large language models is using that to scale and bring predictive medicine to the masses.
01:08:24.000When I came on your podcast last time, we had thousands upon thousands of people register.
01:08:30.000In my model, a clinician spends 45 minutes with you reviewing your lab results, deep diving into every aspect of you at the biological level, deep diving into your gut biome.
01:08:42.000Whatever test it is we do, we're going to spend the time and we want to educate and empower patients and give them sovereignty over their health because they're used to a system where they go in, they're given a drug and they're pushed out and they leave going, why?
01:09:00.000I want patients to be educated and informed and make autonomous decisions that they drive, right?
01:09:08.000And so the goal is to use large language models to give them a resource.
01:09:12.000Imagine if I can take the best and brightest minds in medicine and put them in your fucking pocket 24-7.
01:09:18.000Imagine if you had Huberman and Atiyah in your pocket and it's 2am and you got a question about NAD. You just ask Alan.
01:09:28.000The large language model is going to know all that and he's going to be able to tie it to your medical records and he's going to be able to tie it to the pharmacy and know what date your prescription shipped.
01:09:37.000And the only reason I'll be able to do that when we go back to data in, data out, right?
01:09:42.000In our LLM model, it will be a closed infrastructure.
01:09:46.000I'm not going to give the AI access to the internet, right?
01:09:50.000The plan is we're going to peer review, we're going to look over anything that's loaded into that algorithm, and we're going to allow him to practice in the way that a ways to well clinician would practice and answer questions.
01:10:02.000He won't be there to provide medical care.
01:10:04.000He'll be there to be a medical resource.
01:10:06.000And everything he does, or the AI does, will be monitored and approved by clinicians.
01:10:13.000But what it does is it allows me to drive down the cost of healthcare, right?
01:10:37.000I think you're going back to sick care.
01:10:54.000I'm not saying that they're not a valid clinician at what they do, but it's like asking a jujitsu guy to teach you Muay Thai.
01:11:04.000I would rather put my faith in large language models that know jujitsu, that know Muay Thai, that know MMA, that know boxing, that know all of the history of those things and those modalities, that know every single product that we offer at Ways to Well That immediately can recall your previous conversation,
01:11:21.000what happened, these large language models.
01:11:24.000So in the demos, he'll literally chart everything that we discuss and put it in writing and load it into an EMR. You've got to understand, when my clinicians do a 45-minute call, they've got to spend 15 minutes reviewing everything,
01:11:40.000refreshing their memory, trying to go back over everything you talked about.
01:13:37.000You know, like if you ask them questions about certain things, they will not answer you or they will not, you know, mock Joe Biden or they will not praise Donald Trump, like those kind of things where you're getting political or ideological influence.
01:13:56.000I think you—so the article that I alluded to earlier, Google Has No Moat, this article was basically saying it doesn't matter what large language model you have because it's only going to act in accordance with the data.
01:14:11.000And if every large language model has the same accessibility to the same data— Then how are you going to differentiate your large language model?
01:14:20.000And if everyone puts the same restrictions and requirements on these large language models, how will it differentiate?
01:14:27.000Where I'm going with this is ours would be a closed infrastructure.
01:14:31.000It wouldn't reach out to the internet to get an answer.
01:14:33.000Any data that we put into our large language model will be approved and peer reviewed by our team of clinicians.
01:14:40.000So today, I have brilliant people on my team.
01:14:43.000I have Dr. Grant, a board-certified urologist.
01:14:46.000I have Dustin Loveland, an orthopedic surgeon trained under Jimmy Andrews, one of the godfathers of orthopedic surgery.
01:14:53.000I have Ian White, PhD from the Ansari Stem Cell Institute, 22 years at the bench.
01:15:00.000And I'm reaching out to thought leaders in their field and in academia throughout the country and saying, hey, do you want to help me do something cool?
01:15:23.000To talk about politics or to crack jokes with your friend, our tool would be used to assess large amounts of data, which is what this thing is phenomenal at.
01:15:31.000It's going to, like I said before, tie into your electronic medical records, review your last consult, be able to read your blood report because it's all analytics driven.
01:15:44.000And so almost all the reports and all of the decision trees that primary care clinicians and even a ways to well clinician makes Are essentially algorithms.
01:15:55.000And the more data we can give the large language model, the better decisions it can make.
01:16:02.000And so I'm envisioning there's a day where large language models potentially, you know, take over a lot of the heavy lifting that primary cares and internal medicine doctors do today.
01:17:00.000And literally days before, insurance cut all of it out from under us, quit reimbursing everything, got rid of all the genetics testing, any compounded medication, any of it, gone overnight.
01:17:14.000I had to look a hundred and fifty fucking people in the eye and say I came up short.
01:18:20.000I mean, stem cells, whether it's mesenchymal stem cells, BPC-157 peptides, all these different modalities, all these different tools that you use, they fucking work.
01:20:31.000But the gist of it is, there was just a study done in orthopedics that Red light therapy helped reduce osteoarthritis better than steroid injections and the other treatment options that they're using in the marketplace in orthopedics today.
01:20:49.000Huberman breaks it down and explains it through using red lights.
01:20:53.000There's long wave and short wave, right?
01:20:55.000And the long wave pierces through the epidermis into all of the tissue in your body, all the way to the cellular level, all the way to your cells, spurring Cellular turnover and increasing ATP, which is cellular energy.
01:21:10.000And so it gives your body the energy needed to heal itself.
01:21:33.000I know it works because I'm a part of it.
01:21:35.000And what's fascinating is the ability to maintain.
01:21:38.000Because everyone's worried about getting old and getting decrepit.
01:21:41.000But if you're not seeing any decline as you age in your ability to maintain your physique, your endurance, your energy levels, we haven't done this before.
01:21:54.000This hasn't been something on a large scale that human beings have participated in while they were going through this process of degeneration, the natural degeneration that most people experience as they get older.
01:22:12.000You asked me about low testosterone and what could have caused it, and I look at that and I go, it's everything, right?
01:22:20.000Like, there's another, when we get back to red light, red light, or not red light, Green and blue light can increase testosterone levels, right?
01:23:01.000These are all just basic questions that we could ask and dive into to help patients optimize their hormone levels.
01:23:07.000But what happens if, like for me, I was up at 4am to go get into the operating room.
01:23:12.000I stood in the operating room and would come out and it would be dark again.
01:23:15.000I didn't see the light of day for like 13 years, like literally.
01:23:20.000And so I look back now and I'm like, well, of course, because what happens is if you don't get sunlight, your body upregulates melatonin and melatonin reduces testicular function and drives down testosterone.
01:23:33.000And they believe it's because we evolved, like, essentially being, when we were cave dwellers, we would, in the winters, in the cold time of the year, our rhythms would change with the environment, and we would go and be more indoors.
01:23:45.000That wasn't the best time to breed or procreate.
01:23:48.000And so in the spring, in the summer, when there's more sunlight, you're in the sun more, and your melatonin level deregulates, your testosterone level upregulates, and all of a sudden, you're fertile.
01:25:29.000And so if you if let's just say in a in a miracle world all the sudden Blue Cross Blue Shield rolls out a large language model to streamline your experience and they want to tie into your wearables.
01:25:42.000The last person you want digging through your underwear drawer is the insurance company because they're going to use it to limit your care to limit what they cover and to kick you off a plan.
01:25:53.000They're going to know when the chronic disease is coming, and they're going to charge you when they know they can monetize you.
01:25:59.000And then as soon as you reach a state where they can't, and that's the dangerous side of these large language models, and that's the dangerous side of the tool.
01:26:08.000And so a sword in the right hands is, you know, one thing, and a sword in the wrong hands is a whole other thing.
01:26:17.000I wonder if they are trying to do that.
01:26:19.000I wonder if these insurance companies are- Oh, they're for sure going to roll that out.
01:26:24.000Like, when you have an insurance-based model, and that's where I would tell you, maintain the car outside of the system, right?
01:26:31.000And the insurance-based large language models are going to ensure that you stay on these treatments because that's where they're profitable.
01:26:50.000And they were put in place to negotiate the price of pharmaceutical drugs for the average American.
01:26:55.000Because so many drugs were coming into the marketplace, the government couldn't get to and decipher what drugs make sense, what drugs don't make sense, what should we cover, what should we not cover.
01:27:05.000So they allowed pharmacy benefit managers to do that.
01:27:08.000Within a decade the big insurance companies went out and acquired pharmacy benefit managers.
01:27:14.000Within a decade from that date, the pharmacy benefit managers began to negotiate rebates to themselves, not discounts to the patient.
01:28:13.000The pharmacy benefit manager gives a tier pricing.
01:28:16.000That tier pricing is not based on what drug is best for you.
01:28:20.000It is based on what drug is best for their financials.
01:28:23.000And so they prioritize drugs in a tier pricing under the misnomer to the American people that a tier 1 drug is the best drug and a tier 4 drug is not as good.
01:28:36.000But the truth is a tier 4 drug is not as profitable.
01:28:41.000And so let's say, let's go back to the insulin example.
01:28:46.000The average price of this insulin is $381 is what the Senate Finance Committee found.
01:28:51.000$381 on, I can't remember if it's Sanofi, I think, was their price.
01:28:56.000Out of that, the pharmaceutical company got less than $40.
01:29:01.000So that remaining $200-something stayed at the pharmacy benefit manager.
01:29:08.000Okay, pharmacy benefit managers are making billions upon billions of dollars a year.
01:29:13.000They decide what gets covered, what goes on your insurance plan, what your co-pay is, what your deductible is, and they can move any lever at any time.
01:29:21.000So, examples, let's go back to GLP-1s, right?
01:32:05.000They're raising our rates because they claim they paid $14,000 a month for his drug, right?
01:32:10.000He had a huge out-of-pocket burden on that drug, but was happy because he thought, well, hey, man, it was going to be $14,000 and I only had to pay X. And then they never paid the 14 because they negotiated a rebate on the back end.
01:32:24.000And then they turn around and they mark up my insurance plan for all my employees every year, year after year.
01:32:32.000It is a profit-driven system, not a patient outcome-driven system.
01:32:36.000And so that's all I'm trying to hammer home with patients.
01:32:40.000When you say, why don't you take insurance?
01:32:42.000Because insurance is the crux of the problem.
01:32:45.000You cannot operate in that ecosystem and provide quality care.
01:33:44.000If I can monetize your diabetes, why would I cure or prevent your diabetes?
01:33:52.000And I know if I'm a bigwig at United or Cigna that you're going to switch jobs in three years and by the time that diabetes leads to metabolic disease and a cascade effect that puts you in a hospital that costs me more money, you're somebody else's problem.
01:34:09.000Or, if I can stall it long enough, you're the federal government's problem.
01:34:13.000And so, every aspect of healthcare is focused on that quarter, on that time frame.
01:34:20.000Another terrible example of surgery, and this is honest to God.
01:34:24.000I talked to my buddy who's a president at an orthopedic company.
01:34:26.000He told me he was sitting down with a surgery center about joints.
01:34:30.000And there's a new joint that they have, and it's more expensive, but the efficacy data of the long-term benefits on it Astronomically outperform the other joint that this hospital system was using.
01:34:42.000He sat down with the CEO of the hospital and he said, here's the data, five years out, here's what we're seeing, dah, dah, dah, dah, dah.
01:34:51.000The CEO said, I don't give a shit what happens five years out.
01:34:56.000Swear to God, this is a call I had yesterday.
01:34:58.000He said he looked me in the eye, Brigham, and he said, if you told me that this joint will last at least 90 days and it's cheaper, that's all I care about.
01:35:09.000Because all of their data and records and accountability are only on the first 90 days.
01:35:14.000Once you're out of that 90 day and you've done your little review and all that, you're off again and you're no longer a monetizable patient.
01:35:22.000And so, too, when we talk about primary cares and what's happened, the same thing with pharmacies where they've been gobbled up by insurance companies if they're in the insurance model is the same thing that happened with primary care practices.
01:35:35.000The day of a primary care being independent and a free thinker is over.
01:35:49.000Because now they have the patient population.
01:35:51.000If I can get you at the primary care level, then I can control the referral of where that primary care sends you as we profiteer off your disease state.
01:36:12.000The methylfolate test tells me my genetics, but there's epigenetics.
01:36:18.000The choices I make every day impact which genes turn on and which genes turn off.
01:36:24.000If nobody ever has a conversation with me in my 30s about my hormone levels, about getting into the sun, about eating right, and you push me towards chronic disease because you wrote me a prescription to treat a symptom and now I go through this system and I get cancer.
01:36:42.000That primary care is going to refer me To an oncologist.
01:36:47.000And that oncologist is part of that same system.
01:37:12.000Russell Brand said this, and he was spot on.
01:37:14.000Another guy who's not a clinician but understood what's going on here.
01:37:17.000If we make things about profits and quarterly earnings and big business and not patient outcomes, don't be shocked when we get phenomenal quarterly earnings and piss poor patient outcomes.
01:37:38.000So this is an article where they were trying to...
01:37:41.000The insurance companies were trying to incentivize them to use a generic in this instance because this is one of those issues where there's no rebate and no way for the insurance company to monetize it.
01:37:51.000But it breaks down how much money these guys...
01:37:54.00065% of an oncologist's income comes from that.
01:38:27.000You will not get these treatment modalities and you will not have these conversations and you will not do that deep dive.
01:38:35.000So in a dream world, what I'm envisioning as we build this multidisciplinary institute here in Austin and we open these facilities across the country is a lot of the care will be virtual and will be managed from the comfort of your own home, driven by large language models that are tying into your wearables and all those things we talked about earlier.
01:38:54.000But we first have to establish a baseline.
01:39:27.000If you can be in the top 25% of VO2 max, you reduce all-cause mortality by 400%.
01:39:33.000Okay, so now you combine that with a DEXA. Now you combine that with a gut biome.
01:39:39.000Now you combine that with a gene test where we know what genes you have, what are your genetics.
01:39:43.000Now we can help guide you on how to prevent epigenetics, how to prevent and use epigenetics to prevent disease states from chronically manifesting.
01:39:53.000And we can truly get proactive and predictive.
01:39:58.000When you said living to be 106 or 112, whatever you said, Peter Atiyah talks about this too.
01:40:04.000The difference between somebody dying at the average human life expectancy and making it to be a centenarian, the only difference is the onset of chronic disease.
01:40:15.000So today, Can we stop or slow the progression of chronic disease and buy brilliant minds like David Sinclair, like Ian White, my stem cell buddy, who's our chief science officer.
01:40:30.000Can we buy them time to see if they can unlock the code?
01:40:34.000Because when Ian breaks it down, and I definitely want to get into stem cells.
01:41:58.000But the first step is to get proactive, to take yourself out of the system, to do the data, because we can't improve what we don't measure.
01:42:06.000So if you were to come in and establish that baseline that I was talking about earlier, we now have a full comprehensive analysis of where you started the day you started treatment.
01:42:17.000The only test I hadn't got to yet is an EEG. So for me, we do...
01:42:33.000The example of where AI can be used for great things is they use artificial intelligence to analyze an EEG and to put it into a report that a layman, you know, Neanderthal like me can understand.
01:42:47.000I was able to look at this report and tell How my neurons are firing, where my neurons are misfiring, how my neurons are losing bandwidth from the posterior of my brain to the prefrontal cortex of my brain.
01:43:08.000We know that it has over an 80% success rate.
01:43:12.000Way more efficacious than any SSRI, which have been debunked and proven to be bullshit too.
01:43:19.000Way more than any of these antidepressants, anti-anxiety meds, and it's a permanent fix.
01:43:24.000We scan your brainwaves and then from there we can use a technology called MERT which is a magnet and the AI will give you a precision approach to rewiring your brain.
01:43:36.000So it uses a magnet to pull those firing neurons down the correct path.
01:43:40.000And so let me quantify it and give you an example of how it works.
01:43:44.000For me, my brain, so the human brain has variances.
01:43:48.000Some brains are moving as slow as 6.5 hertz, you know, top tiers 13 hertz.
01:43:53.000And that's how fast you can analyze data.
01:43:56.000And so if there was a red dot, and I flashed it up on a screen, and I flash it once, Everyone will see that, as long as they're above 6.5 Hz.
01:44:05.000If I flash it twice really fast, anyone below 9.5 Hz, they won't be able to make that signal connect to the prefrontal cortex to assess that it flashed twice.
01:44:29.000It's years of sleepless nights, stress, anxiety, epigenetics, diet, nutrition, head trauma, these athletes with concussions.
01:44:40.000So they're using it mainly to treat athletes with depression from concussions and brain injuries.
01:44:46.000And we can't fix the anatomical issues of the brain, but we can help those neurons fire appropriately and maximize the delivery of the bandwidth of the signal.
01:44:57.000And so through brain mapping, we're able to create a precision plan where that magnet is literally tuned to the frequency of my brain and is able to drive that 12.5 hertz all the way from the posterior to the prefrontal cortex.
01:45:40.000I immediately think, what about, they're using it a lot with high-level operators.
01:45:43.000They've already signed all these government Department of Defense contracts, and they're using it for Navy SEALs, for snipers, for people who have to make split-second decisions under high-pressure environments.
01:45:55.000You want that neuron firing all the way through.
01:45:58.000I would imagine it would be good for comedy.
01:46:41.000I'm not maximizing my brain's potential.
01:46:44.000And then I go to, okay, when we talk about the four horsemen, diabetes, atherosclerosis...
01:46:52.000Cancer, and then the last one's neuropathic decline, Alzheimer's, and neurodegeneration.
01:47:00.000When we begin to use these tools and allow AI to get ahead and get proactive instead of reactive, then we can start to assess your baseline.
01:47:10.000And now we've monitored not just your biomarkers, not just your gut health, not just your genetics and your epigenetics.
01:47:17.000We're now also monitoring your brain health and your neurowave health.
01:47:22.000And we can refine that with a precision approach.
01:47:24.000And the traditional model uses a magnet as well, but it's only indicated if you, let's go back to the insurance.
01:47:31.000The only indication where you can use this technology and have insurance cover it is somebody who's failed two or more SSRIs.
01:47:41.000Okay, at that point, you've been taking drugs for over a year.
01:48:45.000So, we have a letter of intent with Bruce Dahmer, and we're in negotiations with Dell Medical University to be part of their psychedelic research institute.
01:48:57.000And what that would allow us to do is, Bruce has done a spin-off of MAPS, and the premise is it's called MINES, and it's using low-dose psychedelics to see if we can optimize human brain performance.
01:49:11.000He came on your podcast I think like 10 years ago.
01:49:15.000He said y'all played pool and he left that next morning and went and did ayahuasca and solved some equation that he had been working on for like a decade and came out the other end of ayahuasca with the answer.
01:50:35.000So I would really like to try the difference between trying something like AlphaBrain Black Label and then doing that study and see if it has an impact on whether or not it's more efficient.
01:51:04.000I want to dive even deeper to explain to the listeners and to clinicians, because so many clinicians will say, you cannot get stem cells, or stem cells are bullshit, or they don't work.
01:52:11.000And so they're saying, okay, if it doesn't differentiate, then it doesn't do anything, right?
01:52:16.000And so it's because the term that David Sinclair used, heterochronic parabiosis, right?
01:52:25.000When you take an old mouse and you merge its organ system with a young mouse, the old mouse gets younger, right?
01:52:32.000Okay, heterochronic parabiosis happens in a mother when she's pregnant.
01:52:36.000Dr. Ian White, again my chief science officer who has educated me on all of this, this isn't me talking, he released a study where he talked about This is occurring in a woman when she's pregnant with a child.
01:52:56.000Her heart increases its capacity in the third trimester by 50%.
01:53:01.000It is not just the mother supporting the baby.
01:53:04.000It is the baby and young genes and protein codes supporting the mother and helping optimize her health to create an environment that is synergistic for both the baby and the mother that allows that baby to have an optimal environment.
01:53:20.000So when we take those cells, an orthopedic surgeon says you have to use HSCs.
01:53:28.000You have to use HSCs if you need them to differentiate.
01:53:33.000HSCs will differentiate, they'll migrate.
01:53:36.000What is an HSC? It's a different type of stem cell that they're pulling out of the bone marrow.
01:53:42.000And so, but the problem with that is to extrapolate that HSC, you're pulling it from like you, you're in your 50s.
01:53:49.000You have 50 something year old HSCs, right?
01:53:53.000We know from the moment of birth Those HSCs' viability begin to decline rapidly.
01:54:01.000And year after year after year, I think it's like 1 in 10,000 once you're over the age of 30. You may be getting 10,000 HSCs, but only one of them is a viable HSC that'll actually do anything.
01:54:14.000When we look at what's happening with these cellular treatment options that are placental derived or birth tissue derived, it's the same exact product that they're using over in Panama, that they're using in all these other locations.
01:54:28.000You're just not allowed to expand them in a petri dish.
01:54:32.000And so there's an article that I listed on the Waste Well website because you asked me last time, is there a benefit to expanding the cells?
01:54:41.000And my answer was the optimal dosage is the minimal dosage required to elicit the desired response with the minimal side effect profile.
01:55:15.000So when they're doing these treatments, whether it's in Panama or Tijuana, and they do these petri dish, well, they extract, they expand, they multiply.
01:55:28.000When they have the dosage, what is it based on?
01:55:38.000And so, historically, when an orthopedic surgeon says it's bullshit or it doesn't work, it's because they're misunderstanding the mechanism of action.
01:55:49.000They're assuming if an MSC comes from an umbilical cord or from a birth-derived tissue, It can't differentiate.
01:55:58.000And if it can't differentiate, it can't become something.
01:56:02.000And if it can't become something, then it can't heal something because it's not going to become a tendon or a tendon cell and heal that tendon.
01:56:10.000You have to take a step back and go to the whole analogy of the young rat and the old rat, right?
01:56:23.000And you look at that and you say, okay...
01:56:26.000When we put these young, vibrant cells in a body, it's not just the cells.
01:56:31.000Yes, you're getting mesenchymal signaling cells, which are going to go to that site of injury and trigger your body's own cells to come.
01:56:39.000Those cells transfer their mitochondria into your cells and their job's done.
01:56:43.000They're out of your system in a few days.
01:56:46.000Okay, from that point forward, the magic happens with all the other goodies that are included in that treatment.
01:56:53.000The extracellular vesicles, the exosomes, the cytokines, the scaffolding, the RNA, right?
01:57:00.000And so the example I can give is with a facial treatment, right?
01:57:03.000We do a skin pen and we treat you with cellular treatment modalities and acellular, both.
01:57:09.000But regardless, it will have RNA. RNA is a message, a messenger code, that allows your cells to get a young, healthy message.
01:57:19.000Like I said, parabiosis, when the mother's pregnant, the baby's also improving her health.
01:57:24.000It's not just her improving the baby's health.
01:57:26.000Those same messages are in that tissue that we're putting in your body or on your skin.
01:57:33.000And what they do is, think of it like a construction site.
01:57:37.000If you're going to build a building, you not only need all the essential elements and essential ingredients or products to build that building, but you also need the blueprint.
01:58:12.000You know, now you've got orthopedists saying they don't work, and it's because of, one, people have over-promised.
01:58:19.000Two, you know, they don't understand the mechanism of action, and I think they're kind of thinking, well, they're not differentiating, so it wouldn't work.
01:58:58.000The team doctor's interviewing for his job all the time too, right?
01:59:02.000So if you're the team doctor and you practice good old traditional 20 year old tried and true orthopedic surgery, You're not putting anybody at risk.
02:01:02.000And I just think a lot of it comes down to dogma.
02:01:08.000Misunderstanding, frustrations with over-marketing and people promising people the world.
02:01:13.000Also that these doctors and surgeons are a part of this same system that you've already highlighted.
02:01:17.000They're not independent and completely outside of it.
02:01:20.000If they were, they wouldn't be hired by the biggest teams in the world.
02:01:23.000They want the most accredited, the most Decorated doctors to perform on these incredible athletes that are extremely valuable to these organizations.
02:01:36.000They're not gonna just risk it on some fucking witch doctor.
02:02:53.000And Dr. White and I have talked about this, and this is another thing we're going to be doing at the new facility here in Austin, is we're building a state-of-the-art lab.
02:03:02.000And we are going to do the work at the bench.
02:03:04.000Because Dr. White is on the precipice of being able to use HSCs, the cells that do differentiate, but we will not pull them from bone marrow.
02:03:13.000We will take them from the umbilical cord tissue, the youngest, healthiest, most vibrant cells in With all the extracellular vesicles and goodies, and if we can harness those cells and use those cells, they would be able to differentiate.
02:03:28.000Now, the reason you would want to do that is down the road to be able to rebuild cartilage, or, you know, the critiques that guys have, like, Jamie, could you pull up?
02:03:46.000Yeah, not that I know of, but Dr. White has some really fascinating stuff he's done at the bench, and he's been, that's why he and I were talking about, let's do it.
02:04:43.000Even with these GLP-1s, you know, there's a whole deal that came out, I think in the Orthopedic Journal, where they're talking about now that people are taking GLP-1s and losing all this weight.
02:04:56.000Right now there's a spike in orthopedic surgeries because one of the prerequisites is you have to be healthy for surgery.
02:05:01.000Well that one of the biggest risk factors for knee issues is being obese, right?
02:05:06.000You've worn that joint out carrying all that weight around so they want to get the weight off then do the surgery, right?
02:05:11.000But what's coming is Is there will be less of those surgeries as we get the weight off these people, right?
02:06:07.000Ultrasound-guided interarticular injection of expanded umbilical cord mesenchymal stem cells in the knee for osteoarthritis, the safety, the efficacy, and the MRI data.
02:07:21.000It's providing the building blocks and it's providing the RNA, which is the instruction.
02:07:26.000Here's an example that's easy to show is, again, my skin.
02:07:29.000We've treated, I don't even know, thousands of people, and when you use these cellular treatments on skin, it improves skin elasticity, it reinvigorates the cells, it improves collagen production, and it improves fibroblasts,
02:07:45.000and it does it through the exact same method.
02:07:48.000You're getting the message of a young, healthy, vibrant cell.
02:07:51.000All those little codes in the cellular form of RNA are being loaded into your cells and telling your cells to act young again, essentially.
02:08:00.000And it's causing, I don't want to call it a reversing in aging, but it's definitely slowing aging and improving cellular health.
02:08:08.000And then you combine that with things like red light therapy.
02:08:11.000And all these different treatment modalities that are being ignored.
02:08:17.000Like, I mean, I can send you, I didn't tag them on the WasteWell website, but I could send Jamie dozens of articles or you could listen to Huberman where he breaks it down.
02:08:51.000Literally, they were saying the new conspiracy theory is you didn't really tear your Achilles or it was a partial tear.
02:08:57.000And Aaron was so gracious about it and said, well, hey, I'm glad that Americans are now questioning things instead of just basically like a few years ago they weren't.
02:09:07.000And they're saying this just because he's recovered so quickly.
02:09:21.000They did use an Arthrex technique, and a lot of people are saying it was a state-of-the-art...
02:09:25.000The Arthrex technique was being used a decade ago when I was in the operating room.
02:09:29.000So, it is a procedure that's been around.
02:09:31.000Now, I do know one of the unique things they did with Aaron was, or not unique, but one of the newer things they did was an internal brace, which gives you a little bit more protection in the early phases of the healing process.
02:09:44.000But Aaron's recovery, Aaron getting approved by the clinicians to get on the field faster, all of those things are because Aaron thought outside the box and Aaron is doing all of these extra things that I think most traditional medicine is ignoring.
02:10:01.000And Aaron was open-minded enough to do that.
02:10:52.000But Aaron was telling me, Aaron Alexander, not Aaron Rodgers, was telling me that the clinical team was looking at his Achilles and were very impressed with how much blood flow and how healthy the Achilles already was.
02:11:06.000And so, you know, I mean, that's a catastrophic injury.
02:11:10.000And his recovery time is amazing, and it's because of all the things he's doing.
02:11:20.000But, I mean, again, he's worked his ass off, and he's done all the right things, and he's got a documentary that's going to show the world all the things that he did and how hard he worked to get back for that team.
02:11:33.000So I just think it's really, really cool stuff.
02:11:34.000I'm not taking credit for his healing.
02:11:37.000I'm thankful that we got to play a small part, but I just think the main gist of that message is...
02:11:43.000There are other alternative treatment options and I think a lot of times orthopedic surgeons view it as we're trying to say not to have surgery.
02:11:52.000There are times where you definitely need surgery and my message is when you have surgery why would you not Why would you not want to optimize that?
02:12:25.000Man, I would tell you, we should absolutely throw everything at the kitchen sink at you to heal.
02:12:35.000Whether that's IGF, whether that's testosterone optimization, red light therapy, hyperbaric, all of those things are going to contribute to the healing process.
02:12:50.000There's gonna be a bunch of people going over this with fucking notes and trying to remember everything, but I think what you're doing is very important and I think the message, I'm very happy that we can get that message out there because there's a lot of people, and including me, that didn't really understand how difficult the situation truly was until it's laid out in a comprehensive manner.
02:13:10.000And you know, this is the reason why you're getting bad information from your primary physician, this is the reason why you're getting bad information It's a complicated, fucked up, convoluted system that is compromised by money.
02:13:34.000We didn't even get into CRISPR and all the things that are coming in the future.
02:13:38.000But I'm hoping to be on the cutting edge of that.
02:13:40.000So the last thing I'll say is, if you're a PhD, if you're in academia, if you're interested in these things, if you want to make a difference in the world, we're hiring.
02:13:49.000We're hiring pharmacists, we're hiring pharmacy techs, we're hiring across the board, nurse practitioners, any of it, any and all of it, and also to anyone who's part of that AI world and tech world.
02:14:06.000I've been bugging Lex to try and hook me up with some of his contacts, but it hasn't manifested yet, so we're looking for all those positions if you're sick of being part of a broken system.