The Jordan B. Peterson Podcast


520. Is Your Diet Killing You? | Dr. Benjamin Bikman


Summary

Dr. Benjamin Bickman is a professor of cell biology at Brigham Young University and a lecturer at Peterson Academy. He's done 3 courses for us, and we're talking today primarily because I'm interested in, and not only in the rise of the Make America Healthy Again movement, and I've been talking to the people who are involved in that movement and trying to determine, strategize about the direction. And that's a very complicated thing to do.


Transcript

00:00:00.000 If only people were sitting around on a Friday night listening to us chat and thinking,
00:00:04.680 oh, I really want a stick of butter.
00:00:06.120 They want something sweet and gooey.
00:00:07.900 We crave carbs, and they have myriad metabolic effects, one of which is to spike insulin.
00:00:14.480 What happens to type 1 diabetics if they eat nothing but fat?
00:00:17.380 The fat cells get big.
00:00:18.660 They get so big that they have to tell insulin, I'm done.
00:00:21.720 A government issues a mandate telling its people what to eat, and boy, they got it wrong.
00:00:25.820 All those vegetables and fruits have been genetically altered to a degree
00:00:29.000 that's just beyond comprehension.
00:00:30.760 A purely plant-based diet is so deficient in nutrients,
00:00:34.040 it is utterly incompatible with human survival.
00:00:36.200 Studies in men have shown that if man stops eating meat,
00:00:39.280 his testosterone plummets, his sperm production plummets.
00:00:42.340 Listen to that, man.
00:00:59.000 Hello, everybody.
00:01:01.800 The first thing I think I'll tell you is that I'm on tour again from February through June
00:01:06.780 through the United States, in Canada, and in Europe.
00:01:10.280 And if you want more information about that, go to jordanbpeterson.com and check it out
00:01:15.620 so that you can come and see me and my wife if you're inclined to do that.
00:01:20.560 But I'm talking today to Dr. Benjamin Bickman, who's a professor of cell biology at Brigham Young
00:01:26.360 University and a lecturer at Peterson Academy.
00:01:29.240 He's done three courses for us.
00:01:30.960 And we're talking today primarily because I'm interested in, and not me only, obviously,
00:01:39.940 in the rise of the Make America Healthy Again movement.
00:01:43.840 And I've been talking to the people who are integrally involved in that movement
00:01:50.120 and trying to determine, strategize about the direction.
00:01:54.640 And that's a very complicated thing to do.
00:01:56.740 And one of the things I want to do is figure out where the most bang for the buck might be had
00:02:02.000 with the least amount of trouble.
00:02:04.580 Almost every problem's like that.
00:02:06.140 There's lots of causes of a given problem,
00:02:08.340 but there's one or two causes that are 90% of the problem.
00:02:11.720 And you want to focus there.
00:02:13.840 And maybe have a chance then.
00:02:16.160 And so I talked to Dr. Bickman today about insulin resistance.
00:02:20.920 And really, to put that in more simple terms, excess carbohydrate intake.
00:02:26.580 And that's the carbohydrates that are rapidly transmuted metabolically into sugar.
00:02:33.340 And that's pretty much all carbohydrates, by the way.
00:02:35.580 And the fundamental problem with America's health is an abundance of carbohydrates.
00:02:42.360 And so we discussed insulin resistance, which is a metabolic condition that arises as a consequence
00:02:51.280 of too much carbohydrate intake.
00:02:52.880 And then we discussed the multiplicity of cascading catastrophic health effects that produces type 2 diabetes being particularly well-known, let's say, as a secondary consequence.
00:03:07.540 But cancer, heart disease, erectile dysfunction, reproductive dysfunction, more generally, high blood pressure, you name it.
00:03:19.100 Immunological disease, depression, anxiety.
00:03:22.000 There's almost no serious medical condition that's widespread that can't be traced to excess of carbohydrate intake.
00:03:32.760 And so obviously, it seems to me, that's where the focus should be.
00:03:37.580 And so we walked through the biology.
00:03:40.080 We walked through the practicalities.
00:03:42.040 We walked through some hypotheses about how that problem might be redressed at the government level,
00:03:48.940 but also at the level of individual behavior.
00:03:50.760 And so this is very important.
00:03:53.560 There's likely nothing you can do that will improve your life more, both in the short run, but even more importantly in the long run,
00:04:03.080 than to modify your diet away from high-carbohydrate intake.
00:04:07.440 And so we walked through why that is.
00:04:09.180 So join us.
00:04:10.060 So, Dr. Bickman, I've been talking to the Maha people about their plans, and it's clearly the case that Americans, Westerners more broadly,
00:04:26.840 but particularly Americans maybe, are suffering from a slew of unfortunate medical conditions.
00:04:35.060 So what I'd like to know from you to begin with is if you had to rank order the magnitude of the medical problems that presently confront the West, let's say, particularly the U.S., how would you do that?
00:04:51.300 There's a very specific reason I'm asking.
00:04:53.840 Yeah.
00:04:54.360 You know, whenever there's a problem, maybe you can, if it's a complex problem, maybe you can point to like a dozen, two dozen causal elements.
00:05:03.380 But if you focus, you'll find that three of those are the major contributors.
00:05:09.920 And you could spend an immense amount of time on all two dozen, or you could focus like hell maybe on the worst problem and gain 50% of the ground.
00:05:20.240 If you spread your forces out across the entire panoply of problems, you're not going to get anywhere.
00:05:25.200 Like, if there are 24 stakeholders in the system that are making America sick, and you take on all 24, all you're going to do is fight endless battles.
00:05:36.920 So I'm curious, if you had to zero in, you know, to where you'd get the most bang for the buck, when you look at the health of America, what do you see as the major impediments, the major problems?
00:05:49.760 Yeah. Yeah. But if you look at the top 10 killers, you can actually thematically lump them all into what I call the cardiometabolic crisis, where that encompasses the problems that are overtly metabolic, like type 2 diabetes, which is a top 10 killer.
00:06:06.320 I think it comes in around number six or seven, but also number one, which is heart disease.
00:06:11.160 And now there are others in the top 10, like Alzheimer's disease, for example, that you wouldn't think you'd say, okay, well, Ben's not including Alzheimer's disease in these cardiometabolic killers.
00:06:22.920 And yet I actually am.
00:06:24.680 Even certain forms of cancers are viewed increasingly as a metabolic problem.
00:06:29.740 So it might be that I'm the guy with the hammer, and so I see the nail, but the nail is poor metabolic health.
00:06:37.180 And that's certainly the focus of my efforts.
00:06:39.240 But I like how you framed the question.
00:06:41.460 As much as metabolic health is an underlying issue or a common soil from which all of these noxious plants are growing that we call diabetes, heart disease, Alzheimer's disease, COPD, chronic obstructive pulmonary problems,
00:06:56.220 the alternative view isn't that these are each distinct problems.
00:07:00.860 It's just that there are various manifestations of the same problem, namely insulin resistance being the most common disorder.
00:07:09.000 Within the United States, a study published out of the University of North Carolina a number of years ago found that 88% of adults have at least one part of what we call the metabolic syndrome,
00:07:21.160 which is a kind of cluster of complications, interestingly and tellingly, what we call the metabolic syndrome used to be called the insulin resistance syndrome.
00:07:32.020 And as much as you framed it from a Western view, just to help people appreciate this, we aren't even in – we're maybe around in the U.S. number 20 or so with type 2 diabetes worldwide.
00:07:44.360 Right.
00:07:44.580 The Middle East, they're experiencing these problems far worse than we are.
00:07:49.020 Even Southeast Asia, these countries where you'd look at the population and think, well, you look healthy.
00:07:55.520 You're only maybe a little overweight.
00:07:57.300 Yeah.
00:07:57.640 But there are ethnic differences where body fat, which is so important to this, will predispose people to these metabolic problems at varying levels.
00:08:05.320 But to answer the question succinctly, the problem is a cardiometabolic crisis, and at the heart of this is this very poorly understood, well, poorly known, poorly discussed problem called insulin resistance.
00:08:19.120 Yeah, okay, okay.
00:08:19.960 So lay out the relationship between insulin resistance and obesity.
00:08:26.900 Oh, yeah.
00:08:27.640 Oh, that's a great question.
00:08:29.680 So insulin resistance is the most common problem.
00:08:32.260 It's the most relevant for chronic disease.
00:08:33.900 Naturally, we want to know, all right, well, where did the villain come from?
00:08:37.180 Yeah.
00:08:37.300 What is the Breaking Bad story?
00:08:39.100 I typically describe and teach that there are two paths.
00:08:43.240 There's fast insulin resistance, which has its own noxious stimuli, that it comes quickly and it can go quickly.
00:08:52.640 But then there is slow insulin resistance, and this touches on your question, so I'll answer it with that one in mind.
00:08:58.520 One of the ways in which insulin resistance develops is by fat cells that get too big.
00:09:04.960 Now, to really confirm, as much as we have an obsession on fat, on body fat, we actually look at it kind of incorrectly.
00:09:15.020 We would say, okay, Jordan has 20 pounds of fat, whereas Ben has 30 pounds of fat.
00:09:21.900 So Ben's naturally going to be sicker than Jordan, and yet it's not the mass that matters most.
00:09:27.440 It's actually the size of each individual fat cell.
00:09:29.940 This is why in that cardiometabolic crisis, the list of what's killing us, men die more from all of those except Alzheimer's disease.
00:09:39.260 So if you look at the top 10, nine of them go to men, and it's not even close.
00:09:43.560 Men die more from these problems than women by orders of magnitude almost.
00:09:48.140 But women are fatter than men, and so it's clearly not an issue of fat mass.
00:09:53.920 Per se.
00:09:54.820 Yeah, yeah.
00:09:55.200 So if you look at it as a percent body fat, a woman's going to be fatter than a man by design.
00:09:59.360 That's supposed to be that way for reasons that we won't get into.
00:10:03.220 But men have less body fat, but we have bigger fat cells.
00:10:08.000 So I promise I'm answering the question.
00:10:10.180 But as a fat cell gets bigger and bigger, it's almost like a naughty little child who's taken the water balloon to the tap.
00:10:16.500 Now they're filling it, filling it, filling it, filling it.
00:10:19.600 Oh boy, you better take that balloon off or it's going to pop.
00:10:23.540 Now the fat cell, acting in its own best interests, it has to adapt two ways to ensure that it doesn't pop.
00:10:32.300 It doesn't want to die in the body.
00:10:33.780 We don't want our fat cells.
00:10:35.200 We don't want any cell to die.
00:10:36.520 That's a very messy, very inflamed process.
00:10:39.480 So one thing, the fat cell, as it gets ever bigger, it can't turn off the fuel coming in.
00:10:47.420 But what it can do is change the fuel coming out.
00:10:50.540 So insulin has an absolute choke hold on fat cells.
00:10:55.100 This is a little outside the question, so I won't quite get around to it yet.
00:10:59.080 But insulin is an absolutely essential signal.
00:11:02.040 As much as we focus on calories, insulin tells a fat cell to grow.
00:11:06.800 And now the fat cell is growing and it's telling insulin,
00:11:09.740 Insulin, I am about to pop and so I have to stop listening to you.
00:11:15.000 And so I'm going to become deaf or I'm going to become resistant to what you're telling me to do.
00:11:20.280 And whereas earlier insulin was telling it to hold on to all of this fat,
00:11:24.200 now the fat cell starts leaking out fat, even though insulin was originally telling it not to.
00:11:29.080 This creates a problem that we can refer to as ectopic fat deposition.
00:11:35.340 Because now the fat cell is leaking out these things called free fatty acids.
00:11:39.600 At the same, so blood fat levels are going up.
00:11:42.960 Now that's not normally a problem necessarily, but that should only happen when insulin is low.
00:11:48.340 Now we have this weird state where insulin is high,
00:11:51.380 which should be telling the fat breakdown to slow down.
00:11:54.920 I'm getting into deep biochemistry actually really quickly.
00:11:57.580 So normally if insulin is up because we've eaten some carbs and stuff,
00:12:02.560 then fat in the blood would be down because insulin would be telling the fats to hold on to it.
00:12:06.480 But now, or when we're fasting or low carbohydrate diet,
00:12:10.420 then insulin is down and now we're mobilizing more fat.
00:12:14.400 So normally the biochemistry and the endocrinology is such that if insulin is high, fats are down.
00:12:19.620 If insulin is low, fats are up.
00:12:21.180 Unless the fat cells are overfilled or have undergone hypertrophy or a growth expansion,
00:12:27.160 now you have high insulin and high fats.
00:12:31.280 And so the body can't burn that fat.
00:12:33.020 It has to store it.
00:12:34.600 And so now we start storing fat in tissues that are ill-suited,
00:12:37.780 like the pancreas is getting fat.
00:12:39.900 Why isn't it just excreted?
00:12:41.740 Wow, that's a great question.
00:12:43.760 So actually, if you'll allow me, I love that you just ask the question why.
00:12:47.920 I tell my students that when you ask a scientist a why question,
00:12:52.220 especially a cell biologist, my answer is God only knows.
00:12:55.740 So I don't know why God designed the system to work that way.
00:12:58.600 Why not excrete the fat?
00:12:59.960 Maybe it's because historically the probability of prolonged nutrient availability at that level was like zero.
00:13:11.640 Oh, yeah, for sure.
00:13:12.500 I mean, we're living in a very unique day.
00:13:14.540 Yeah, yeah, yeah.
00:13:15.520 So the rule would have been historically, if you have extra food, hold on to it.
00:13:20.540 Hold on to it because hard times are coming.
00:13:22.700 So that is in fact reflective though of insulin's effect.
00:13:25.620 It is so determined to store energy that it will literally depress metabolic rate.
00:13:30.720 It will prevent any wasting of energy.
00:13:34.280 So that's the first problem with touching on the question of what's the connection between obesity and insulin resistance?
00:13:39.700 Because there is a connection.
00:13:41.280 So the fat cells get big.
00:13:42.540 They get so big that they have to tell insulin, I'm done.
00:13:46.020 I can't get any bigger.
00:13:47.140 So I'm going to leak out the fats even though you don't want me to.
00:13:49.920 But then there's a second feature that just compounds the problem,
00:13:53.200 which is as the cells are getting bigger and bigger and fat cells can grow unlike any cell in the body.
00:13:59.060 No cell in the body is capable of the expansion that a fat cell is capable of, much to our chagrin.
00:14:06.420 But as the fat cells getting bigger and bigger,
00:14:08.820 they're pushing each other further and further away from capillaries,
00:14:12.780 from the smallest base unit of the blood vessel and all of its life-giving oxygen.
00:14:17.640 And as it's getting pushed further and further away,
00:14:20.680 the poor chubby fat cell is becoming hypoxic or it's suffocating.
00:14:26.040 And in an effort to ensure its survival,
00:14:28.700 it starts slowly dripping out these pro-inflammatory proteins called cytokines,
00:14:34.060 basically just hormones that turn on inflammation.
00:14:37.220 And there's a whole bunch of them, dozens of them.
00:14:39.880 But some of them will correct the problem.
00:14:43.060 It's like a trail of breadcrumbs.
00:14:44.720 And rather than Hansel and Gretel coming,
00:14:46.860 it's getting to the capillary and stimulating the growth of a new blood vessel.
00:14:51.180 And so it's kind of the fat cells way of crying out,
00:14:54.320 hey, I'm lacking oxygen, come feed me.
00:14:56.800 And so we have that happen.
00:14:58.660 So both of these things, we pity the poor fat cell.
00:15:02.280 It's become so filled because of our lifestyle,
00:15:05.500 which is a whole other topic worth diving into.
00:15:08.060 But it becomes insulin resistant to ensure its own survival,
00:15:11.900 spreading fat to be stored throughout the body.
00:15:13.800 And then it becomes pro-inflammatory to try to correct its blood supply.
00:15:19.140 And that then, the inflammation is one of the fast causes of insulin resistance
00:15:24.200 that I alluded to a moment ago.
00:15:25.860 That any time inflammation is turned on on the body,
00:15:29.780 yes, that is an immune process,
00:15:32.380 but the overlapping of the immune and the metabolic is profound.
00:15:37.080 Just a moment ago, you and I were speculating on the,
00:15:39.660 why the system may be designed the way it is.
00:15:42.000 One thing we know for certain is that of all the systems in the body,
00:15:46.660 the immune and the metabolic are not only essential to survive times of deprivation
00:15:52.620 and to defend the host, but they work hand in hand.
00:15:56.840 After all, what good is it trying to mount an immune response
00:15:59.680 if the warriors don't have any energy to work with?
00:16:02.760 So anytime inflammation is up and it's staying up,
00:16:06.100 that's going to cause insulin resistance.
00:16:08.440 And indeed, it is one of the main causes of insulin resistance.
00:16:11.600 Okay, okay.
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00:17:18.820 Okay, so let's walk through this from stage one
00:17:23.580 and also let everyone know what the health consequences are.
00:17:29.100 So I'm going to start the outline.
00:17:31.100 You tell me if I get it wrong and elaborate wherever you want.
00:17:34.600 All right, so we have access to an endless number,
00:17:40.760 an endless array of carbohydrates,
00:17:43.000 and they're very easily converted into sugar.
00:17:45.480 Yes.
00:17:45.880 So we have access to sugar of various forms
00:17:48.840 and to carbohydrates in absolute plenitude.
00:17:52.400 Yes.
00:17:52.960 Right.
00:17:53.340 And so that's easily converted.
00:17:55.820 That's very high energy source,
00:17:58.340 very dense energy source,
00:17:59.900 and it's easily converted to fat.
00:18:01.580 And so that's what happens.
00:18:03.680 And the reason that happens is because
00:18:05.380 we're evolved for lean times,
00:18:08.800 and we store excess energy like a grizzly bear or a camel,
00:18:12.560 and we do that so we don't starve to death in the winter.
00:18:16.420 And thank goodness for it.
00:18:17.820 Right, right.
00:18:18.440 And you see this,
00:18:19.680 I guess some of the proof of that is that
00:18:21.620 islanders who tend to be evolved to get through lean times,
00:18:26.560 they're very, very efficient in their metabolism.
00:18:28.900 If they go on a North American high-carb diet,
00:18:32.800 they just balloon.
00:18:33.920 Oh, yes.
00:18:34.500 Yeah.
00:18:34.780 Okay, so now,
00:18:37.000 too many carbohydrates and sugars,
00:18:39.300 too much fat.
00:18:40.900 Now, the consequence of the fat is manifold.
00:18:44.880 One of the consequences is,
00:18:47.260 you alluded to two.
00:18:49.340 One is that insulin resistance increases,
00:18:52.620 and the other is that inflammation increases.
00:18:54.640 Okay, so I think what we should do first
00:18:57.140 is we should outline the role of insulin
00:18:59.440 in bodily metabolism.
00:19:01.700 Yes.
00:19:02.080 Okay, so why don't you do that,
00:19:03.720 and then tell everybody why insulin resistance is bad.
00:19:07.940 Because what you've done so far
00:19:09.520 is make a case for why it promotes
00:19:11.860 cellular fat cell function.
00:19:15.800 But it also has catastrophic effects systemically.
00:19:19.660 Okay, so talk about what insulin does,
00:19:21.520 and then talk about what insulin resistance does.
00:19:24.140 Okay, because just so everyone's clear,
00:19:26.140 what we're trying to do here
00:19:27.020 is we're trying to zero in
00:19:28.180 on the most egregious
00:19:30.020 of the multitude of health problems
00:19:31.820 that might plague us.
00:19:33.400 And we're making a case
00:19:34.400 for insulin resistance
00:19:36.720 as perhaps the worst.
00:19:38.200 It contributes to all sorts of diseases,
00:19:39.900 but it's also highly associated with obesity,
00:19:42.240 which has a variety of health problems as well.
00:19:45.000 Okay, so let's focus on insulin to begin with.
00:19:47.600 Tell people what insulin does,
00:19:48.960 and then what insulin resistance does.
00:19:50.600 Yeah, yeah, brilliant.
00:19:52.220 Yeah, insulin is an absolutely essential hormone
00:19:55.240 in the body.
00:19:56.100 As much as I am going to go on
00:19:58.380 in the next few minutes
00:19:59.120 and paint the picture of it being a villain,
00:20:01.640 it's critical.
00:20:03.640 If you don't have it,
00:20:04.580 you have a disease called type 1 diabetes,
00:20:06.600 and you will die.
00:20:07.820 Type 1 diabetes used to be a death sentence.
00:20:09.980 In the absence of insulin,
00:20:11.400 the body will not last long.
00:20:13.180 And so it is here for a purpose.
00:20:15.540 We need it.
00:20:16.100 However, we need it to work in our favor.
00:20:19.760 And to do that,
00:20:20.820 we need it to be generally keeping in a normal range.
00:20:24.720 And so you just a moment ago
00:20:26.460 framed the question
00:20:27.440 by pointing a finger at carbohydrates.
00:20:29.620 I agree with that completely.
00:20:31.500 That's a whole topic.
00:20:32.860 As much as over the past decades,
00:20:34.900 we vilified dietary fat.
00:20:37.280 Oh boy, we got it wrong.
00:20:38.880 And wouldn't you know it,
00:20:39.920 you know,
00:20:40.100 in the first time we're in history,
00:20:42.180 as far as I know,
00:20:43.260 a government issues a mandate
00:20:44.720 telling its people what to eat,
00:20:46.060 and boy, they got it wrong.
00:20:47.620 No surprise, right?
00:20:48.940 That has happened so often
00:20:50.400 when you take things to that level.
00:20:52.320 So if we put the blame where it belongs,
00:20:54.800 not only are carbohydrates
00:20:55.840 the only macronutrient
00:20:57.460 that people have an addiction for,
00:20:59.320 no one's addicted to fat.
00:21:00.700 No one's addicted to protein.
00:21:02.020 If only people were sitting around
00:21:03.860 on a Friday night
00:21:04.580 listening to us chat and thinking,
00:21:06.460 oh, I really want a stick of butter.
00:21:08.260 No, no one.
00:21:09.100 They want something sweet and gooey.
00:21:10.700 They want something salty and crunchy.
00:21:12.140 So we crave carbs
00:21:13.360 and they have myriad metabolic effects,
00:21:17.260 one of which is to spike insulin.
00:21:19.360 So this is answering the question
00:21:20.640 of what does insulin do?
00:21:22.000 Insulin's most famous effect,
00:21:25.200 but not its only effect,
00:21:26.960 and I would even say
00:21:27.760 not its most important effect.
00:21:29.740 Its most famous effect
00:21:31.120 is to look at that rise in blood sugar
00:21:33.660 or blood glucose and say,
00:21:35.240 that's beyond homeostasis.
00:21:37.700 This isn't right.
00:21:38.600 If that stays high for long,
00:21:39.960 it's going to start harming the body
00:21:41.460 because hyperglycemia alone is pathogenic.
00:21:45.520 And so insulin acts as a hero
00:21:47.040 and says, your problem,
00:21:48.680 I'm going to take care of you.
00:21:50.020 It brings the temperature back down
00:21:51.960 like a thermostat,
00:21:53.160 you know, the perfect example
00:21:54.180 of homeostasis,
00:21:55.160 brings the glucose back down to normal.
00:21:57.320 And then insulin, having done its job,
00:21:59.440 retreats back into the background,
00:22:01.300 if you will.
00:22:02.200 But what's its chemical role
00:22:03.600 in relationship to the conversion
00:22:05.400 of carbohydrate to energy?
00:22:07.240 Oh, yeah, yeah, right.
00:22:08.380 That's a great question.
00:22:09.380 So glucose, you'd mentioned a moment ago,
00:22:11.660 and as you did so,
00:22:12.420 I sort of couldn't help but think
00:22:13.760 of the kind of a metaphor
00:22:15.660 of like engines
00:22:16.560 where glucose,
00:22:18.480 the body has two primary fuels.
00:22:20.940 At any moment,
00:22:21.840 it's either sugar burning,
00:22:23.160 blood glucose,
00:22:23.980 or fat burning.
00:22:25.400 One is like a kind of race car engine.
00:22:28.220 Boy, it's going to be really quick.
00:22:29.500 You don't have a lot of fuel
00:22:30.540 and you're going to get
00:22:31.100 terrible gas mileage,
00:22:32.560 but boy, it's going to be a quick ride.
00:22:35.500 The other is like a big diesel engine
00:22:37.800 rumbling down the roads of Alberta,
00:22:40.000 hauling,
00:22:40.420 going across the Trans-Canada Highway
00:22:42.120 and taking its load.
00:22:43.020 It's going to go forever.
00:22:44.740 It's never going to run out of fuel.
00:22:46.000 That's the fat metabolism.
00:22:47.080 That's fat metabolism.
00:22:48.540 And now the next question is,
00:22:49.900 well, who decides?
00:22:51.300 Insulin decides.
00:22:52.580 Insulin, once again,
00:22:54.080 when it comes to any metabolic effect,
00:22:56.280 you need never go further than insulin.
00:22:58.080 There are other hormones
00:22:58.860 that want to pretend that they matter.
00:23:00.740 Thyroid kind of matters.
00:23:02.180 Cortisol kind of matters.
00:23:03.760 Insulin rules them all.
00:23:06.480 And insulin, if it's up,
00:23:07.980 it dictates it's time for sugar burning.
00:23:10.220 If insulin's down,
00:23:11.740 then the body says,
00:23:12.820 all right, it's time for fat burning.
00:23:14.660 In fact, that's where
00:23:15.680 the whole ketogenic aspect comes from.
00:23:18.600 When insulin's down,
00:23:20.260 it is so incompatible
00:23:21.880 with the body storing energy
00:23:23.680 that it literally begins burning more fat
00:23:26.520 than it knows what to do with.
00:23:28.020 It's met its energy needs already,
00:23:30.140 but it can't stop burning fat.
00:23:31.840 And so it starts burning more than it needs.
00:23:33.920 And that more, if you will,
00:23:35.340 becomes ketones.
00:23:36.420 It's sort of a metabolic release valve,
00:23:38.820 like a pressure release valve
00:23:40.200 of a way of saying,
00:23:41.540 I'm burning more than I need.
00:23:43.040 And so I've gone beyond
00:23:44.640 what the cell requires.
00:23:45.820 So ketones are going to become
00:23:46.880 a good alternative.
00:23:48.460 But then back to,
00:23:49.580 or transition.
00:23:50.260 Would you think that the,
00:23:52.160 like historically, again,
00:23:53.560 over an evolutionary time span,
00:23:56.860 easily digestible high sugar carbs
00:23:59.580 would have been essentially non-existent, right?
00:24:01.960 They would have been...
00:24:02.920 Imagine what we would have had to do
00:24:04.300 to get them.
00:24:05.000 We either had to prepare for battle
00:24:06.700 against a hive of bees.
00:24:08.200 Right, right.
00:24:09.020 When we could find them.
00:24:10.500 Yes, when we could find them.
00:24:11.820 Or further,
00:24:12.740 when we could find
00:24:13.560 a digestible carbohydrate,
00:24:16.120 you know,
00:24:16.340 maybe berries or something.
00:24:17.600 Right.
00:24:17.780 Because people need to...
00:24:18.580 Or tubers.
00:24:19.260 Yeah, that's right.
00:24:20.100 Right.
00:24:20.300 We have to appreciate that
00:24:21.600 what we eat
00:24:23.320 is either going to defend itself
00:24:24.900 by claw or by chemical.
00:24:27.000 And a plant doesn't have
00:24:28.080 the advantage of running away
00:24:29.200 or attacking back.
00:24:30.560 So if we dropped
00:24:31.300 any number of us
00:24:32.380 in the wilderness,
00:24:33.600 good luck.
00:24:34.540 Yeah, yeah.
00:24:35.080 Well, we have to...
00:24:35.780 Even if you're surrounded
00:24:36.220 by plants.
00:24:36.720 Well, we have to understand, too,
00:24:37.680 that like we might think
00:24:38.720 that historically human beings
00:24:40.560 existed on the kind of vegetables
00:24:42.480 that we have now,
00:24:43.580 but, or fruits.
00:24:44.500 But all those vegetables
00:24:45.720 and fruits have been
00:24:46.660 genetically altered
00:24:47.460 to a degree
00:24:48.060 that's just beyond comprehension.
00:24:49.500 I mean, if you look
00:24:50.640 at the origin plant
00:24:52.600 of corn,
00:24:53.820 I mean, it doesn't look
00:24:54.800 anything like...
00:24:55.520 It looks nothing like corn.
00:24:56.460 Even look at an apple.
00:24:57.680 Right, right.
00:24:58.300 Look at an apple
00:24:58.800 a hundred years ago.
00:24:59.740 It was these teeny
00:25:00.800 little crab apples.
00:25:01.900 Sour things.
00:25:02.460 Now they're these
00:25:02.920 big, juicy sugar bombs.
00:25:04.000 Yeah, yeah, yeah, exactly.
00:25:04.980 But the more we eat
00:25:05.940 these sugar bombs
00:25:07.260 and they're like,
00:25:08.160 the more glucose is going up,
00:25:09.740 the more insulin has to come up.
00:25:11.440 And now we've come
00:25:12.240 to what I believe
00:25:12.960 is in fact
00:25:13.540 the main driver
00:25:14.640 of insulin resistance
00:25:15.620 as I transition
00:25:16.740 to insulin resistance,
00:25:17.620 which is too much insulin.
00:25:19.500 And people may hear that
00:25:20.920 and think,
00:25:21.320 hold on,
00:25:22.280 you're talking about
00:25:22.900 insulin resistance.
00:25:24.020 Too much insulin
00:25:25.140 is the main cause
00:25:26.480 of insulin resistance.
00:25:28.260 And lest it seem
00:25:29.680 a little unexpected,
00:25:31.380 it is a fundamental
00:25:33.000 biological principle.
00:25:34.620 Too much of something
00:25:35.780 will cause a resistance
00:25:37.280 to that something.
00:25:38.480 Right.
00:25:38.820 Whether it's body
00:25:39.900 or soul,
00:25:40.860 if we are exposed
00:25:41.900 to a stimulus
00:25:42.940 over time,
00:25:44.740 that noxious stimulus,
00:25:46.320 it becomes noxious
00:25:47.400 and we try to adapt.
00:25:49.380 Well, dose matters, right?
00:25:50.360 There's lots of things
00:25:51.100 that are healthy
00:25:52.000 in proportionate dose.
00:25:54.220 That's exactly right.
00:25:54.620 Okay, so now
00:25:55.020 we're eating carbs continually,
00:25:58.080 let's say.
00:25:58.420 All the time.
00:25:58.900 So we're relying
00:25:59.580 on this fast energy source.
00:26:01.820 One consequence of that
00:26:03.180 is storage in fat.
00:26:04.460 Yes.
00:26:04.860 One consequence of that
00:26:06.060 is if there's too much
00:26:06.900 storage in fat
00:26:07.640 is that triggers
00:26:08.300 its own form
00:26:09.060 of insulin resistance.
00:26:09.980 But you also alluded
00:26:11.440 to an insulin resistance,
00:26:12.620 I believe,
00:26:13.260 that's merely a consequence
00:26:14.920 of insulin
00:26:16.060 that spikes too high.
00:26:17.200 That's right.
00:26:17.520 So there's multiple reasons
00:26:18.720 for insulin resistance
00:26:19.740 in a heavy carb-loaded diet.
00:26:22.060 Oh, yes.
00:26:22.520 All of them become
00:26:23.280 relevant there.
00:26:24.160 Yes, so we've now
00:26:25.360 kind of gone to both here.
00:26:27.320 The slow insulin resistance
00:26:28.880 is the slow and steady growth
00:26:30.220 of the fat cell,
00:26:31.560 which we outlined earlier.
00:26:33.160 And that's a consequence
00:26:33.980 of insulin being up,
00:26:35.780 telling the fat cell to grow.
00:26:37.580 And then the fat cell is saying,
00:26:38.600 okay, insulin,
00:26:39.260 what do you want me to grow with?
00:26:40.720 Ah, it's the calories.
00:26:41.880 So you have to have both
00:26:43.220 for a fat cell to grow.
00:26:44.680 And insulin stimulus
00:26:45.560 and sufficient calories
00:26:46.620 to fuel the growth.
00:26:48.100 Then we have
00:26:48.660 the fast insulin resistance.
00:26:50.300 I mentioned inflammation.
00:26:51.640 That is one.
00:26:52.840 And then the other one
00:26:53.840 that is the main one,
00:26:54.860 I argue,
00:26:55.420 is too much insulin itself.
00:26:57.460 And then once the body
00:26:58.460 becomes insulin resistant,
00:26:59.940 now you really can
00:27:01.220 start going down
00:27:02.020 that list of chronic diseases
00:27:03.740 that are the top 10 killers.
00:27:06.020 And to a one,
00:27:07.400 you can see how insulin resistance
00:27:09.420 is either the main contributor
00:27:12.320 or one of the main contributors.
00:27:14.480 To all of them.
00:27:15.000 Yeah, to all of them.
00:27:16.200 Right, right, right.
00:27:16.340 Type 2 diabetes
00:27:17.100 is entirely a disease
00:27:18.720 of insulin resistance,
00:27:19.680 where over time,
00:27:21.500 if you have two variables,
00:27:22.660 the insulin and the glucose,
00:27:24.700 one of the great tragedies
00:27:26.060 from a metabolic scientist
00:27:27.360 with diabetes,
00:27:28.380 type 2 diabetes,
00:27:29.080 is that we have
00:27:30.600 a glucose-centric paradigm.
00:27:33.380 Just to use this
00:27:34.120 as an example
00:27:34.700 of how insulin resistance
00:27:36.060 contributes to disease,
00:27:37.740 the conventionally trained clinician
00:27:39.760 only looks at the glucose.
00:27:41.920 They may not have
00:27:43.160 even ever measured the insulin.
00:27:45.160 And when I give these kinds
00:27:46.100 of talks to physicians,
00:27:47.720 they can't even wrap their head
00:27:49.060 around insulin
00:27:50.060 being a marker that matters.
00:27:51.300 And yet the irony is
00:27:52.160 it's the one that matters most.
00:27:53.740 Because over the life
00:27:54.660 of the person
00:27:55.180 with type 2 diabetes,
00:27:56.700 their insulin has been coming,
00:27:58.420 been going higher
00:27:59.340 and higher and higher.
00:28:00.660 But the glucose
00:28:01.340 is staying normal.
00:28:02.560 Blood glucose.
00:28:03.240 Blood glucose.
00:28:03.700 And so when they come in
00:28:04.680 for their annual checkup,
00:28:05.860 the physician just says,
00:28:07.360 well, glucose is normal,
00:28:08.280 so you're good.
00:28:09.380 But you have high blood pressure.
00:28:11.600 Well, guess what the leading
00:28:12.360 cause of high blood pressure is?
00:28:14.320 Insulin resistance.
00:28:15.380 Or they may say,
00:28:16.640 you have fatty liver disease.
00:28:18.900 Right.
00:28:19.100 Guess what the leading cause
00:28:20.160 of fatty liver disease is?
00:28:21.820 You have early signs
00:28:23.000 of cognitive decline
00:28:24.100 or dementia.
00:28:25.100 Right.
00:28:25.560 None of those are glucose-
00:28:26.800 Diabetes type 3.
00:28:27.340 Exactly.
00:28:28.040 Right.
00:28:28.380 Yes.
00:28:29.000 Where now the brain's
00:28:29.940 becoming insulin resistant.
00:28:31.040 And if we could shift
00:28:32.340 the paradigm
00:28:33.040 to an insulin-centric paradigm,
00:28:35.680 that they would have detected.
00:28:37.100 And then it's 20 years later
00:28:38.620 where they finally see,
00:28:40.320 oh, your glucose is high.
00:28:41.960 Well, now-
00:28:42.320 Yeah, but it's worse than that,
00:28:43.480 I think,
00:28:43.900 if I remember correctly.
00:28:45.140 Because,
00:28:46.080 so you said that
00:28:47.100 one of the ways
00:28:48.200 that physicians are marking
00:28:49.440 whether you're healthy
00:28:50.300 is to look at your
00:28:51.140 blood glucose levels.
00:28:52.800 But they age-correct those.
00:28:54.620 So that the norms
00:28:56.940 for you at 50,
00:28:58.780 what would be normal
00:29:00.040 at 50
00:29:00.780 is diabetic at 20.
00:29:02.720 But that makes no sense
00:29:05.360 because if your blood sugar levels
00:29:08.000 are as high at 50
00:29:10.140 as they would have been in 20
00:29:12.080 if you would have been
00:29:13.060 diagnosed diabetic,
00:29:14.540 it's just as bad for you
00:29:15.960 at 50.
00:29:16.700 Oh, in fact,
00:29:17.180 it's even-
00:29:17.260 So that's insane.
00:29:17.860 It's an insane correction.
00:29:19.640 In fact,
00:29:19.900 it's even more pernicious.
00:29:21.360 If you look over time
00:29:22.600 at what the diabetic cutoff
00:29:24.840 used to be
00:29:25.440 over the past 70 or so years
00:29:27.740 since that became a marker,
00:29:29.640 So that's been
00:29:30.340 gerrymandered as well.
00:29:31.640 It's been slowly coming down.
00:29:32.640 And you would say,
00:29:33.160 well, why bring it down?
00:29:34.660 It's because the easier it is
00:29:36.400 for people to stumble over,
00:29:37.700 the easier it is to diagnose,
00:29:39.200 and then the easier it is to say,
00:29:40.580 I need to give you a drug.
00:29:42.220 And that is what I believe
00:29:43.720 is partly at the heart
00:29:44.900 of the glucose-centric paradigm.
00:29:46.800 You can't drug insulin.
00:29:48.800 It's too stubborn.
00:29:49.700 There's no drug
00:29:50.660 that's going to push
00:29:51.340 your insulin down.
00:29:52.120 But there are drugs
00:29:53.500 that will push
00:29:54.020 your glucose down.
00:29:55.600 And so it's a hell of a way
00:29:56.680 to diagnose someone
00:29:57.580 with a problem sooner
00:29:58.680 and give them
00:29:59.740 a drug prescription,
00:30:01.200 multiple drug prescriptions.
00:30:02.640 But the great irony,
00:30:04.040 or I would say irony
00:30:05.360 as if it's an innocent mistake-
00:30:06.880 Murderous irony.
00:30:07.800 Yes.
00:30:08.260 The more the clinician
00:30:09.460 is pushing the glucose down,
00:30:11.760 indeed,
00:30:12.780 with some medications
00:30:13.780 that push the insulin
00:30:15.120 up even higher,
00:30:16.680 they actually kill
00:30:17.600 the patient more.
00:30:18.800 Even though you've corrected
00:30:19.960 their blood glucose problem,
00:30:21.260 just the absolute proof,
00:30:22.940 it's not the marker
00:30:23.780 that matters.
00:30:24.740 It's certainly not the marker
00:30:25.740 that's causing disease.
00:30:27.120 So the more aggressively
00:30:28.160 you're giving the diabetic
00:30:29.180 more and more insulin,
00:30:30.400 type 2 diabetic,
00:30:31.540 more and more insulin
00:30:32.380 to push the glucose down,
00:30:33.840 they become three times
00:30:35.280 more likely
00:30:35.820 to die from heart disease.
00:30:37.260 You're literally tripling
00:30:38.080 their risk.
00:30:38.200 Which drugs do that?
00:30:39.440 Yeah.
00:30:39.820 That will be drugs
00:30:40.660 like a class of drug
00:30:42.080 called sulfonylurea,
00:30:44.100 which is what's called
00:30:44.820 an insulin secretagogue.
00:30:46.240 It basically takes
00:30:47.140 the beta cells
00:30:47.880 and says,
00:30:48.360 of the pancreas
00:30:49.300 that make insulin.
00:30:50.500 So, hey,
00:30:50.820 we know you're already
00:30:51.680 working overtime.
00:30:53.120 It's not enough.
00:30:54.040 We need to put you
00:30:54.760 in the gulag.
00:30:55.620 You got to work double shifts
00:30:56.920 and we've bumped up.
00:30:57.940 So it drives the insulin levels up.
00:30:59.340 That drives the sugar levels down.
00:31:00.740 Yes, so again.
00:31:01.380 But it increases
00:31:02.080 insulin resistance
00:31:03.040 across time.
00:31:03.760 That's exactly right.
00:31:04.700 So they get fatter
00:31:05.440 and they die faster.
00:31:06.940 Cancer risk doubles.
00:31:08.220 Alzheimer's risk doubles.
00:31:09.400 It's because those aren't glucose.
00:31:10.500 How common are those drugs?
00:31:12.080 Oh, extremely common.
00:31:13.140 Even more common
00:31:13.920 is just giving
00:31:14.640 the type 2 diabetic insulin
00:31:16.100 directly.
00:31:17.260 You're literally giving them
00:31:18.460 more of the very thing
00:31:19.300 that's killing them.
00:31:19.980 So distinguish between
00:31:21.200 type 1 and type 2 diabetes
00:31:22.580 before we go on.
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00:32:14.000 Well, you and I can both,
00:32:18.660 there aren't a lot
00:32:19.380 for some Canadians
00:32:20.340 to be proud of,
00:32:21.200 but Banting and Best,
00:32:22.420 two legendary scientists
00:32:23.580 from Ontario,
00:32:24.280 were the first to discover
00:32:25.460 the one hormone
00:32:26.540 that was absent
00:32:27.380 in type 1 diabetes.
00:32:29.200 At the time,
00:32:29.840 it was called
00:32:30.340 juvenile onset
00:32:31.740 because it was something
00:32:32.980 that would manifest
00:32:33.800 around the age of 10 years old
00:32:35.360 or so.
00:32:36.160 But in type 1 diabetes,
00:32:38.120 that is when the body
00:32:39.240 has killed its own beta cells.
00:32:40.800 Is that an immune problem?
00:32:41.620 An autoimmune disease.
00:32:42.800 It's an autoimmune disease.
00:32:43.600 Yep.
00:32:43.900 So the body has,
00:32:44.900 for some reason,
00:32:45.780 said to the beta cells
00:32:46.820 of the pancreas,
00:32:48.000 you don't look familiar,
00:32:49.200 so we're going to kill you.
00:32:50.640 And so the person
00:32:51.220 has no beta cells,
00:32:52.340 no insulin,
00:32:53.500 no way to control metabolism,
00:32:55.160 and they kind of burn to death,
00:32:56.960 if you will,
00:32:57.580 in a way.
00:32:58.520 They just...
00:32:59.160 What happens to type 1 diabetics
00:33:00.540 if they eat nothing but fat?
00:33:02.320 Yeah, well,
00:33:02.860 that's a great question.
00:33:04.160 In fact,
00:33:04.520 this allows a transition
00:33:05.640 into the actual dynamics
00:33:06.880 of fat cells.
00:33:08.040 So if you had a,
00:33:08.660 in fact,
00:33:09.140 if you look at the earliest diet
00:33:11.320 that was given to diabetic,
00:33:12.800 type 1 diabetics,
00:33:13.680 before they started using insulin,
00:33:15.700 it was almost entirely carnivore.
00:33:18.140 Yeah.
00:33:18.580 You look at these
00:33:19.420 old-fashioned prescriptions,
00:33:21.100 it was this much fatty meat,
00:33:23.220 and it would say fatty meat.
00:33:24.840 Yeah, yeah, yeah.
00:33:25.380 Don't eat meat that is too lean.
00:33:27.280 Right, right.
00:33:27.980 It's because these are fuels.
00:33:29.360 Fat is a fuel
00:33:29.960 that doesn't need insulin
00:33:30.940 to tell it what to do.
00:33:32.040 Yeah.
00:33:32.200 It can get into the cells of the body,
00:33:33.920 the brain,
00:33:34.580 which doesn't use fat,
00:33:35.700 it readily uses ketones,
00:33:37.600 which you'll make plenty of
00:33:38.940 if you're burning a lot of fat.
00:33:40.500 And so that would be
00:33:41.120 the best way to ensure
00:33:42.160 the type 1 diabetic
00:33:42.920 lived as long as possible.
00:33:44.340 But the great tragedy,
00:33:46.320 when we discovered
00:33:47.120 what was missing,
00:33:48.400 professors Banting and Best,
00:33:50.320 by giving these patients insulin,
00:33:52.520 that changed things.
00:33:53.600 Now these people
00:33:54.360 could live a long, happy life,
00:33:56.180 but it shifted the paradigm,
00:33:58.500 which was eat whatever you want
00:34:00.540 and cover it with your insulin.
00:34:02.940 This is a term,
00:34:03.600 any parent listening to this
00:34:05.600 who is a child
00:34:06.460 with type 1 diabetes
00:34:07.820 will have heard this.
00:34:08.980 Asinine advice.
00:34:10.460 This is a disease
00:34:11.400 of not metabolizing glucose
00:34:13.640 very well.
00:34:14.260 Right, right, right.
00:34:14.600 Why would we tell them?
00:34:16.000 And that includes carbohydrates.
00:34:17.500 Oh yes.
00:34:17.800 Because they're converted
00:34:18.360 to glucose.
00:34:18.940 That's exactly,
00:34:19.540 yes, thank you.
00:34:20.260 Yes, so all dietary carbohydrates
00:34:21.680 are going to be converted
00:34:22.500 to blood glucose
00:34:23.260 to some degree or another.
00:34:24.900 Some a lot,
00:34:26.060 like the sugar bomb apple,
00:34:27.580 some very little,
00:34:28.760 like a cruciferous vegetable,
00:34:30.420 like broccoli or something.
00:34:32.160 The inedible vegetables.
00:34:33.080 Yeah, exactly.
00:34:33.700 The ones that you put
00:34:34.620 in front of a newborn,
00:34:35.680 a young little toddler,
00:34:37.240 and they're going to push it
00:34:38.020 off the plate
00:34:38.540 because they inherently know
00:34:39.720 I don't want this.
00:34:41.340 Yeah, so the type 1 diabetic,
00:34:43.720 what used to be a carnivore diet,
00:34:45.300 basically became
00:34:46.060 the same standard
00:34:46.800 high carb diet.
00:34:48.100 But you look at these poor kids
00:34:49.400 with type 1 diabetes,
00:34:50.700 it is a life
00:34:51.740 of constant fluctuations.
00:34:53.220 Right, right, right.
00:34:53.820 The constant anxiety.
00:34:55.580 And yet now we know
00:34:56.820 in human studies
00:34:58.120 what happens
00:34:58.900 if you control the carbs,
00:35:00.600 get them off the roller coaster,
00:35:01.940 sure enough.
00:35:02.780 It flattens.
00:35:03.400 It's a flat line
00:35:04.060 and their insulin dose
00:35:05.460 just plummets.
00:35:06.440 Yeah.
00:35:06.600 And depending on how much
00:35:07.700 you have to pay for insulin,
00:35:08.880 that's a wallet-saving therapy.
00:35:11.620 Let me summarize.
00:35:12.520 So human beings
00:35:15.120 have two metabolic pathways.
00:35:17.560 The one that we relied on
00:35:18.800 until very recently
00:35:19.760 wasn't the carb pathway.
00:35:22.140 That's really an emergency
00:35:23.240 and windfall metabolic system.
00:35:26.800 Quick burning,
00:35:27.720 limited supply.
00:35:29.060 Yep.
00:35:29.480 Yeah, I mean,
00:35:29.800 we have enough carbs to fast.
00:35:32.000 Like truly,
00:35:32.760 if a human was just relying
00:35:33.980 on their,
00:35:34.780 you wouldn't even have
00:35:35.700 to go that dramatic.
00:35:36.300 You have someone fast
00:35:37.180 for 24 hours,
00:35:38.440 they've essentially burned
00:35:39.800 through all of their
00:35:40.760 mobilized carbohydrate storage,
00:35:42.880 their glucose storage.
00:35:43.940 That's done.
00:35:44.720 It's gone.
00:35:45.620 And in fact,
00:35:46.000 that's going to coincide
00:35:47.040 perfectly with ketogenesis,
00:35:50.000 with the ramping up
00:35:50.880 of ketones in the blood.
00:35:52.120 So there's an additional,
00:35:53.460 we'll go sideways here
00:35:54.740 for a second.
00:35:55.260 Well, there's an additional
00:35:56.260 issue there
00:35:57.180 that isn't well understood
00:35:59.360 as I understand it,
00:36:03.000 that historically,
00:36:04.840 again,
00:36:05.560 over an evolutionary
00:36:06.620 time span.
00:36:07.420 There would have been
00:36:07.840 lots of times
00:36:08.620 when we had access
00:36:09.820 to like no carbohydrates.
00:36:11.760 Okay, so now,
00:36:12.860 and maybe some of those times
00:36:14.480 as well,
00:36:15.280 to not much protein
00:36:16.660 and fat.
00:36:17.400 Yeah.
00:36:17.480 So just not much food.
00:36:18.820 Yeah.
00:36:18.980 Okay, so what happens then?
00:36:21.020 Well, you go into autophagy,
00:36:23.900 right?
00:36:24.220 So what happens is
00:36:25.080 your body starts to
00:36:26.080 digest its own tissues.
00:36:28.460 Now, those could be fat,
00:36:29.940 the fat,
00:36:30.640 which would be fine
00:36:31.420 because that's what
00:36:32.080 it's there for.
00:36:32.940 But if you go past that,
00:36:34.760 then there are more,
00:36:36.880 there are tissues
00:36:37.520 that are starting to be digested,
00:36:40.260 auto-digested,
00:36:41.060 that aren't merely for storage.
00:36:43.320 But the body has a hierarchy
00:36:45.080 of self-consuming.
00:36:47.220 So it consumes
00:36:48.380 damaged tissue first,
00:36:50.640 which is of course
00:36:51.780 what it would do
00:36:52.500 because if you digested
00:36:54.040 healthy tissue first,
00:36:55.140 you would just die.
00:36:56.480 So that's a stupid solution.
00:36:58.600 Now, the advantage
00:36:59.820 to digesting
00:37:01.480 damaged tissue
00:37:02.920 is that
00:37:03.580 when you have
00:37:05.120 access to food again,
00:37:07.060 you regenerate.
00:37:08.720 And so one of the consequences
00:37:11.120 of being reliant
00:37:13.180 on an emergency food supply
00:37:14.820 continually,
00:37:15.820 carbohydrates,
00:37:16.620 is that you never enter
00:37:18.200 an autophagy condition.
00:37:20.420 And so you don't repair
00:37:21.860 yourself very well.
00:37:23.160 Well, first of all,
00:37:24.640 do you think that's true?
00:37:25.920 I mean, I've looked into this
00:37:27.260 and that,
00:37:27.780 it looks to me like
00:37:28.760 a carnivore diet
00:37:29.520 mimics autophagy
00:37:31.600 and maybe that's why
00:37:32.540 they're effective.
00:37:33.400 In fact, not only mimics,
00:37:34.580 it enables it.
00:37:35.640 Like just to be clear,
00:37:37.100 but you're touching on
00:37:38.500 like this topic of longevity,
00:37:40.240 which I have,
00:37:41.220 I have followed
00:37:42.540 the modern,
00:37:43.640 I don't want to hijack
00:37:44.260 the question as you're framing it.
00:37:45.280 go ahead, hijack away.
00:37:46.520 Okay, well, yeah,
00:37:47.540 with longevity,
00:37:48.480 you'd think,
00:37:49.200 well, what is a metabolism
00:37:50.000 scientist going to say?
00:37:51.880 Everything.
00:37:52.440 I have everything to say
00:37:53.340 about longevity
00:37:53.920 because it is this process
00:37:55.440 of the cell
00:37:56.000 constantly wondering,
00:37:57.760 how am I doing?
00:37:58.820 Is it time to build
00:37:59.940 or is it time to break?
00:38:01.420 And one of the quirks
00:38:03.540 of longevity or aging
00:38:04.720 is that a cell
00:38:05.500 actually needs to go
00:38:06.540 through both.
00:38:07.540 That I have looked,
00:38:08.220 I have looked with,
00:38:09.200 and guess who decides
00:38:10.400 whether it's building
00:38:11.060 or breaking?
00:38:11.680 Hormones.
00:38:12.480 Right.
00:38:12.760 Hormones.
00:38:12.980 Yeah, well,
00:38:13.240 life is optimized death,
00:38:15.520 right?
00:38:15.960 Well said.
00:38:16.620 You have to die continually.
00:38:20.140 The excess
00:38:20.960 and the,
00:38:22.360 what would you,
00:38:23.240 everything excess
00:38:23.960 about you
00:38:24.580 and everything
00:38:25.000 that's malfunctioning
00:38:26.040 has to die
00:38:26.900 in order for you
00:38:27.520 to propagate yourself
00:38:28.460 across time.
00:38:29.460 So life isn't life.
00:38:30.740 Life is a balance
00:38:31.900 between growth and death.
00:38:33.580 Right.
00:38:34.140 So you want to optimize death
00:38:35.800 and you optimize death
00:38:37.600 with autophagy
00:38:38.480 as far as I can tell
00:38:39.480 and the carbohydrate
00:38:40.240 or carnivore diet
00:38:42.920 optimizes that
00:38:44.420 or can optimize it.
00:38:45.580 Okay,
00:38:45.800 it takes you out
00:38:46.480 of this emergency food supply
00:38:47.860 that makes you fat.
00:38:49.060 I want to ask you
00:38:49.800 about insulin resistance now.
00:38:51.640 Now,
00:38:51.860 your insulin levels
00:38:52.600 are chronically too high
00:38:53.620 because you're eating
00:38:54.660 too many carbohydrates.
00:38:56.680 What,
00:38:57.840 and tell me
00:38:58.940 the mechanism
00:39:00.140 for insulin resistance
00:39:01.420 and then tell me
00:39:02.700 about its cascading effects
00:39:04.100 so that we can understand
00:39:05.040 the relationship
00:39:05.740 between insulin resistance
00:39:07.460 and diabetes
00:39:08.980 and Alzheimer's disease
00:39:10.560 and obesity
00:39:11.540 and heart disease
00:39:12.560 and cancer
00:39:13.500 and pretty much everything.
00:39:15.120 It's aging
00:39:15.680 for that matter.
00:39:17.020 Yes.
00:39:17.120 Yeah, yeah.
00:39:18.500 Blindness,
00:39:19.700 diabetic,
00:39:20.580 neuropathy,
00:39:21.480 et cetera, et cetera.
00:39:22.740 So let's walk through that.
00:39:24.380 Eat too many carbohydrates.
00:39:25.960 Your insulin levels
00:39:26.680 are chronically high.
00:39:28.400 Insulin resistance follows.
00:39:29.360 Then you get in.
00:39:29.980 Okay, how?
00:39:30.600 How does it follow?
00:39:31.500 What happens?
00:39:32.300 Yeah, yeah.
00:39:32.700 Well, in fact,
00:39:33.460 depending on it,
00:39:34.040 so everything you just asked
00:39:35.360 is so substantial
00:39:36.780 that not only did I want
00:39:38.420 to put it into a book,
00:39:39.520 but even in a Peterson Academy course,
00:39:42.360 it is an answer
00:39:43.640 of about seven hours or so.
00:39:46.260 Yeah.
00:39:46.620 But it is so relevant
00:39:48.660 because again,
00:39:49.320 it's the most common problem.
00:39:50.700 So when insulin is elevated
00:39:51.920 for too long,
00:39:53.000 it literally starts to
00:39:54.360 certain cells,
00:39:55.380 not all cells.
00:39:56.660 And this is one of the reasons
00:39:57.760 why insulin resistance
00:39:58.720 is so pathogenic.
00:40:00.600 It's because some cells
00:40:02.300 become deaf,
00:40:03.580 some cells don't.
00:40:05.120 And so as you have insulin
00:40:06.200 going up higher and higher
00:40:07.440 to the deaf cells,
00:40:08.940 that's not so much a problem,
00:40:10.400 but to the cells
00:40:11.460 who are as acutely sensitive
00:40:13.700 as they were before,
00:40:14.700 now it's stimulating too much.
00:40:16.700 So one interesting example
00:40:17.940 that we haven't even mentioned
00:40:19.060 is infertility.
00:40:20.600 As a Bible-believing fellow,
00:40:23.460 I feel very strongly
00:40:24.340 that it is a commandment
00:40:27.080 to reproduce.
00:40:27.800 So anything that compromises
00:40:28.940 reproduction,
00:40:29.680 as a scientist,
00:40:30.360 I'm quite fascinated by.
00:40:31.960 The most common forms
00:40:33.080 of infertility in men
00:40:35.020 is a problem called
00:40:36.140 erectile dysfunction.
00:40:37.380 The most common problem
00:40:38.580 in women that's a problem
00:40:40.140 of infertility
00:40:40.820 is polycystic ovary syndrome.
00:40:42.700 Both of them are caused
00:40:44.600 by insulin resistance.
00:40:45.760 But it's a perfect example
00:40:47.620 of the kind of
00:40:48.640 two-sided problem
00:40:49.760 where insulin resistance
00:40:50.840 is on one side of the coin.
00:40:53.100 Insulin isn't working very well,
00:40:54.580 but you always have the other,
00:40:57.100 which is that insulin is elevated.
00:40:58.940 So these are two sides
00:41:00.560 of the same coin.
00:41:01.760 And these two problems
00:41:02.780 of infertility,
00:41:03.660 which again,
00:41:04.060 we hadn't even mentioned yet,
00:41:05.400 are both a reflection
00:41:07.280 of one or the other.
00:41:08.540 So in the case
00:41:09.080 of polycystic ovary syndrome,
00:41:10.740 most common infertility in women,
00:41:13.140 people don't appreciate
00:41:14.120 that all estrogens
00:41:15.740 or maybe I'll back up.
00:41:16.800 In order for a woman
00:41:17.600 to have a normal
00:41:18.200 ovulatory cycle,
00:41:19.240 she has to have
00:41:19.980 a big spike in estrogens.
00:41:22.240 So there has to be
00:41:22.940 a big estrogen spike
00:41:24.520 and then that enables
00:41:25.720 and facilitates ovulation.
00:41:27.360 If she doesn't have
00:41:28.520 this big spike in estrogens,
00:41:30.460 the eggs in her ovaries
00:41:32.180 are able to grow,
00:41:33.960 but one never becomes
00:41:35.200 the dominant
00:41:35.680 and actually ovulates.
00:41:37.480 And if one doesn't ovulate,
00:41:39.240 all of those eggs
00:41:40.140 stick around.
00:41:40.980 So then they become cysts.
00:41:42.580 That is the heart
00:41:43.960 of the problem here.
00:41:45.100 Well, it's the manifestation
00:41:46.780 of the problem.
00:41:48.100 Most people don't appreciate
00:41:49.240 that most estrogens,
00:41:51.320 all estrogens
00:41:52.280 were once testosterone.
00:41:54.740 That in men and women,
00:41:56.440 all of the estrogens
00:41:57.380 circulating through the body
00:41:58.620 and in the women,
00:41:59.700 critical to ovulation,
00:42:01.500 have to be converted
00:42:02.480 from testosterone.
00:42:03.940 Well, there is an enzyme
00:42:05.220 called aromatase
00:42:06.400 and her ovaries
00:42:07.260 have a lot of aromatase,
00:42:09.020 whereas the testes
00:42:09.880 in her male counterpart
00:42:10.820 have relatively little aromatase.
00:42:12.900 He's still converting
00:42:14.040 some of his testosterone
00:42:15.260 to estrogens,
00:42:16.040 but not as much.
00:42:17.020 She's doing it a lot more.
00:42:18.940 Insulin inhibits aromatase.
00:42:21.600 So in her body,
00:42:22.920 her ovaries,
00:42:23.700 which maintain
00:42:24.400 an exquisite insulin sensitivity,
00:42:26.440 are looking at all
00:42:27.400 of this insulin
00:42:28.180 and responding,
00:42:29.880 saying,
00:42:30.200 okay, insulin,
00:42:30.960 among the many things
00:42:31.800 you're telling me to do,
00:42:32.940 you're inhibiting the aromatase,
00:42:34.960 which means
00:42:35.620 I have all this testosterone
00:42:37.040 and I can't convert it
00:42:38.720 to estrogens.
00:42:39.760 So not only will she
00:42:40.700 not have the estrogen spike,
00:42:42.400 thereby not ovulating,
00:42:44.280 but she will also have
00:42:45.320 too much testosterone,
00:42:46.500 giving her some
00:42:47.040 of the other symptoms
00:42:47.960 of PCOS,
00:42:49.520 like male pattern baldness
00:42:51.000 or more hair on her body
00:42:53.020 and acne and other problems.
00:42:54.980 Have people been using
00:42:56.060 low-carb diets
00:42:56.980 to treat infertility?
00:42:57.680 Oh, yes.
00:42:58.200 There are case reports
00:42:59.060 published the most common
00:43:00.340 medication that is given
00:43:01.720 to a woman with PCOS.
00:43:03.480 Even if the physician
00:43:04.800 doesn't know
00:43:05.740 to test for insulin resistance,
00:43:07.560 they give a prescription
00:43:08.580 for a drug called metformin,
00:43:10.620 which is the most widely used
00:43:12.120 insulin-sensitizing drug.
00:43:14.240 And it will help,
00:43:15.340 although it's not solving
00:43:16.240 the problem,
00:43:16.900 it's just sort of masking it.
00:43:18.740 Right, so you said
00:43:19.420 erectile dysfunction.
00:43:20.680 Well, so that's
00:43:21.140 the male counterpart.
00:43:22.200 Right.
00:43:22.660 So listen to that,
00:43:24.420 men who are listening
00:43:25.960 to this program,
00:43:27.220 because erectile dysfunction
00:43:29.420 obviously doesn't only
00:43:31.020 affect representation,
00:43:33.480 it affects sex.
00:43:35.480 Yes.
00:43:35.760 And so if you're not able
00:43:37.700 to get it up anymore,
00:43:39.520 one of the ways in principle
00:43:42.500 you could treat that
00:43:43.300 is by reducing
00:43:44.900 your carbohydrate intake
00:43:46.400 dramatically.
00:43:47.300 Oh, yes.
00:43:47.600 Which would also stop you
00:43:48.660 from dying,
00:43:49.760 which is like a good side effect.
00:43:50.860 Yeah, not only will it
00:43:51.540 be more attractive,
00:43:52.400 but more capable
00:43:53.080 of taking advantage
00:43:54.080 of that physical attraction
00:43:55.300 now by not suffering
00:43:56.740 from erectile dysfunction.
00:43:57.900 So really what's happened
00:43:58.900 is we've really,
00:44:00.580 because we've become
00:44:01.440 a society
00:44:03.240 of such insane abundance,
00:44:05.000 we've deviated
00:44:06.460 from our normal diet
00:44:08.480 to an emergency rare diet.
00:44:12.000 Yeah.
00:44:12.300 So now we can just eat
00:44:13.460 the diet we would eat
00:44:14.940 in an emergency
00:44:15.820 that was rare
00:44:16.800 all the time.
00:44:17.820 Yeah.
00:44:17.980 And it turns out
00:44:18.600 that that's not a good idea.
00:44:20.800 No, I mean...
00:44:21.400 Not in the long run.
00:44:22.660 Yeah, for the sake
00:44:23.400 of the species.
00:44:24.480 Yeah, and then
00:44:24.900 with erectile dysfunction,
00:44:26.300 it's not a problem
00:44:27.240 of the insulin being high,
00:44:29.580 but normal physiology
00:44:30.820 in a man,
00:44:31.500 and women,
00:44:32.180 in various locations
00:44:33.200 of the body,
00:44:34.000 is such that
00:44:34.660 when insulin flows
00:44:35.540 through a blood vessel,
00:44:36.900 if the blood vessel
00:44:37.860 is insulin sensitive,
00:44:39.300 the endothelial cells
00:44:40.660 that line the blood vessel wall,
00:44:42.620 they will see the insulin
00:44:43.880 and it will stimulate
00:44:44.700 the production
00:44:45.240 of a molecule
00:44:45.820 called nitric oxide,
00:44:47.200 which will induce
00:44:47.840 vasodilation,
00:44:49.240 an absolutely critical process
00:44:51.220 for erectile function.
00:44:52.920 But those blood vessels
00:44:54.160 become insulin resistant,
00:44:55.560 and now the normal process
00:44:57.480 of vasodilation
00:44:58.380 in a man having
00:44:59.200 normal erectile function
00:45:00.320 is compromised.
00:45:01.460 Okay, so let's step back now.
00:45:02.980 So you said
00:45:03.600 insulin levels rise
00:45:05.240 and then a variety
00:45:06.980 of tissues in the body
00:45:08.160 become insulin resistant
00:45:09.400 because they don't,
00:45:10.540 they can't tolerate
00:45:11.540 being overstimulated.
00:45:13.160 But some of them don't
00:45:14.300 and so they are overstimulated.
00:45:16.420 Okay, and then you...
00:45:18.380 Ovaries included.
00:45:19.480 Right, right.
00:45:20.060 And we talked about
00:45:21.080 the reproductive consequences.
00:45:22.060 Yes.
00:45:22.420 But what other tissues
00:45:24.400 become hyper...
00:45:27.500 are in a hyperreactive state
00:45:29.220 because of too much insulin.
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00:46:24.980 plus a free bottle
00:46:26.100 of fiber and spice.
00:46:30.040 Yeah, right.
00:46:31.100 So there are not many.
00:46:32.680 Most of them go the way
00:46:33.820 of the insulin resistance
00:46:34.920 like the man's side of things.
00:46:37.160 And that's like,
00:46:37.800 for example,
00:46:38.260 what causes Alzheimer's disease
00:46:40.580 where the brain's
00:46:41.300 becoming insulin resistant.
00:46:42.560 But the insulin sensitive side
00:46:43.780 would be a tissue
00:46:44.420 like the liver
00:46:45.740 where one of insulin's effects
00:46:47.820 at the liver
00:46:48.420 is to tell the liver
00:46:49.600 to make fat.
00:46:51.420 Now, the liver
00:46:51.980 is more complicated.
00:46:53.000 I kind of joke
00:46:53.660 with my students
00:46:54.300 that when it comes
00:46:55.060 to metabolism,
00:46:55.880 the liver is the soccer mom.
00:46:57.520 It is sort of giving.
00:46:58.960 It knows what to do
00:46:59.720 with everything.
00:47:00.900 You have a problem,
00:47:02.340 the liver can solve it.
00:47:03.940 It is the ultimate handler.
00:47:06.480 It is the nexus
00:47:07.440 of all nutrient metabolism,
00:47:09.480 whether it's lactate
00:47:10.460 or ketones
00:47:11.100 or fats
00:47:11.600 or glucose
00:47:12.320 or proteins,
00:47:13.660 amino acids,
00:47:14.260 the liver handles
00:47:14.940 all of them.
00:47:15.600 It is the soccer mom.
00:47:16.780 It does everything.
00:47:17.940 And when it comes
00:47:18.520 to insulin,
00:47:20.160 one of the many responses
00:47:21.860 to insulin
00:47:22.440 is to tell the liver
00:47:23.480 to make fat.
00:47:24.980 That effect
00:47:25.740 is as insulin sensitive
00:47:27.040 as ever.
00:47:28.080 And so now
00:47:28.560 in the high insulin,
00:47:29.840 insulin resistant body,
00:47:31.400 the liver is seeing
00:47:32.260 all of that insulin
00:47:33.240 and one of its effects
00:47:34.280 is to tell the liver
00:47:35.400 to make more fat.
00:47:36.580 Is that when you get fatty liver?
00:47:37.720 Then you have fatty liver.
00:47:38.260 The most common liver problem.
00:47:39.560 We also now are seeing
00:47:41.220 signs of fatty liver
00:47:42.300 in children.
00:47:43.380 Oh, yeah.
00:47:43.720 Which is historically
00:47:44.740 unprecedented.
00:47:45.920 Not only that.
00:47:46.820 Alcohol does that.
00:47:48.160 Alcohol does.
00:47:48.880 Right.
00:47:49.260 Too much fructose.
00:47:50.860 Another pointing the finger.
00:47:51.880 Like in high fructose corn syrup?
00:47:53.980 In that kind of fructose?
00:47:55.120 Which is subsidized
00:47:56.500 to a degree
00:47:57.000 that's absolutely stunning
00:47:58.260 and which is in virtually
00:47:59.540 every processed food?
00:48:01.060 Yes.
00:48:01.400 So much of what I rage against
00:48:03.220 when it comes to
00:48:03.880 the government
00:48:04.360 getting involved
00:48:05.560 is it's happened,
00:48:06.940 it's subsidizing
00:48:08.060 the most problematic things
00:48:10.040 like high fructose corn syrup.
00:48:11.440 But even if you and I
00:48:12.400 were drinking orange juice
00:48:13.740 right now,
00:48:14.260 that's a straight shot
00:48:15.240 of glucose
00:48:15.620 or apple juice.
00:48:17.660 You know,
00:48:18.000 if we were meant
00:48:18.560 to drink that fructose,
00:48:20.440 then we wouldn't even
00:48:21.520 have to eat it
00:48:22.220 with the apple.
00:48:23.300 You know,
00:48:23.560 you think,
00:48:24.340 you and I could drink
00:48:25.280 four apples worth
00:48:26.580 of fructose
00:48:27.180 and not even think about it.
00:48:28.540 Right.
00:48:28.920 And yet we'd never want
00:48:29.820 to sit there
00:48:30.260 and eat four apples
00:48:31.400 because the fiber
00:48:32.640 and things would want
00:48:33.400 to slow it down
00:48:34.120 and we'd feel
00:48:34.620 a little more full
00:48:35.480 and so we just,
00:48:37.320 we naturally
00:48:37.800 wouldn't focus
00:48:38.480 as much on it.
00:48:39.440 But this environment
00:48:41.200 that we live in,
00:48:41.960 it's almost like
00:48:43.380 we're eating
00:48:44.660 for winter
00:48:45.800 all the time.
00:48:46.740 All the time.
00:48:47.280 Yeah.
00:48:47.380 Because fall
00:48:47.980 used to be
00:48:48.640 the time of abundance.
00:48:50.020 Right.
00:48:50.100 It was fall
00:48:50.620 when we would reap
00:48:51.240 the harvest.
00:48:51.880 It was fall
00:48:52.320 when the fruits,
00:48:53.000 when the plants
00:48:53.500 would be kind of
00:48:53.940 coming into season
00:48:54.900 and boy,
00:48:56.000 let's get ready.
00:48:57.120 Yeah,
00:48:57.360 like let's lay on
00:48:58.100 some fat
00:48:58.640 like a bear
00:48:59.340 because winter's coming.
00:49:00.960 But winter never comes anymore.
00:49:02.180 That would be not good.
00:49:02.940 Right.
00:49:03.180 Winter never comes.
00:49:04.300 Right.
00:49:04.500 And so anyway,
00:49:05.600 as we go from top to bottom,
00:49:07.220 you can find
00:49:07.920 insulin resistance,
00:49:10.100 you know,
00:49:10.260 the brain,
00:49:11.080 just to find point on it.
00:49:13.420 The brain is
00:49:14.220 one of the high
00:49:15.060 metabolic rate organs
00:49:16.060 in the body.
00:49:16.740 Right now,
00:49:17.200 we're having
00:49:17.540 a stimulating conversation.
00:49:18.940 It is entirely possible.
00:49:20.600 I bet our brain
00:49:21.360 is number two
00:49:22.140 or probably number two
00:49:23.320 highest metabolic rate
00:49:24.320 at the moment
00:49:24.820 because it's so hungry.
00:49:26.900 It's so demanding.
00:49:27.860 Even when we're sleeping,
00:49:29.220 it's busy.
00:49:29.920 So it needs to be fed constantly.
00:49:31.940 The brain doesn't burn fat
00:49:33.380 for energy,
00:49:34.020 for reasons
00:49:34.620 that we don't really
00:49:35.380 understand actually.
00:49:36.800 The brain is its own hybrid though,
00:49:38.940 burning glucose,
00:49:40.000 blood sugar,
00:49:40.880 or ketones.
00:49:42.540 Now,
00:49:43.360 there is in fact
00:49:44.260 a man whom I love
00:49:46.220 and admire
00:49:46.900 is a scientist
00:49:47.940 in northern Ontario.
00:49:49.920 And Stephen Cunane,
00:49:51.080 he presented this idea
00:49:52.440 of a shore-based evolution
00:49:54.380 suggesting that the reasons
00:49:56.840 humans departed
00:49:57.760 in part,
00:49:59.020 we are the only
00:49:59.800 land-based mammal
00:50:00.740 born obese.
00:50:01.340 Buckminster Fuller pushed
00:50:01.920 that theory too,
00:50:02.740 by the way.
00:50:03.180 Really?
00:50:03.360 Yeah,
00:50:03.900 yeah,
00:50:04.140 yeah.
00:50:04.420 Well,
00:50:04.620 it accounts for lots of things
00:50:05.720 like female fat distribution,
00:50:07.860 kind of webbed hands and feet,
00:50:09.620 our ability to swim,
00:50:11.100 hairlessness.
00:50:11.980 Omega-3,
00:50:12.620 the value of omega-3 fats,
00:50:14.040 you know,
00:50:14.220 eating these kind of short-lived foods.
00:50:14.960 Well,
00:50:15.120 where else would you live
00:50:16.240 if you could?
00:50:18.120 Not in the prairies of Alberta,
00:50:19.780 that's for sure.
00:50:20.460 beach where there were lots of shellfish.
00:50:23.060 Absolutely.
00:50:23.420 That's pretty straightforward.
00:50:24.960 It would be a good way to do it.
00:50:26.180 So the brain has these two fuels,
00:50:28.420 glucose and ketones.
00:50:29.480 Ketones are utterly unregulated.
00:50:30.940 If they're going up,
00:50:31.920 in fact,
00:50:32.960 one of the things I love
00:50:34.080 disabusing my students of
00:50:35.320 is the false idea
00:50:36.160 that glucose is the preferred fuel
00:50:37.920 for the brain.
00:50:38.820 Yeah, right.
00:50:39.120 Every sort of knuckle-dragging,
00:50:40.720 mouth-breathing professor
00:50:41.740 will just spout that off
00:50:42.900 without actually knowing
00:50:43.760 a thing about brain metabolism.
00:50:45.580 Yeah.
00:50:45.820 The reality is
00:50:46.800 if someone has glucose levels
00:50:48.560 at 5 to 6 millimolar
00:50:50.260 in a normal range
00:50:51.220 and they're fasted
00:50:52.400 or on a ketogenic diet,
00:50:54.300 even when their ketones
00:50:55.380 get to 1 or 2 millimolar,
00:50:57.340 so over here,
00:50:58.900 the brain has already shifted
00:51:00.180 so that up to 60 plus percent
00:51:02.540 of its energy
00:51:03.120 is coming from the ketone.
00:51:04.420 So don't tell me.
00:51:05.220 So when it has a choice,
00:51:05.660 it'll pick ketones.
00:51:06.160 Indeed.
00:51:06.880 And the moment ketones come online,
00:51:08.900 the brain switches.
00:51:09.880 Even if there's still
00:51:10.820 way more glucose than ketones,
00:51:13.020 don't tell me
00:51:13.560 this is the preferred fuel
00:51:14.740 when this one,
00:51:15.860 even at a fraction of the level,
00:51:17.260 is already the dominant source.
00:51:18.860 Right, right.
00:51:19.400 So the brain...
00:51:19.900 That's so cool.
00:51:20.600 We've been talking to this,
00:51:21.920 my daughter in particular,
00:51:23.200 this guy here in Arizona
00:51:25.540 who runs an old folks home
00:51:27.820 and he's been...
00:51:29.600 So it's like a palliative care
00:51:30.880 old folks home.
00:51:31.520 Yeah, yeah.
00:51:31.700 And he's been putting his charges
00:51:35.040 on a ketogenic diet
00:51:36.800 and people are leaving
00:51:38.260 his home.
00:51:39.380 Yeah, it is one of the great
00:51:41.060 sort of swept under the rug.
00:51:42.580 Right, right.
00:51:43.120 So do you know,
00:51:44.060 like if you have someone
00:51:45.080 who's suffering,
00:51:46.580 especially from early stage Alzheimer's,
00:51:49.120 which we've discussed
00:51:50.440 as type 3 diabetes already,
00:51:52.180 if you switch them
00:51:53.540 to a ketone diet,
00:51:54.540 have there been studies
00:51:55.380 done already
00:51:55.980 showing what the consequences
00:51:57.780 of that,
00:51:58.600 the short-term consequences
00:51:59.760 for cognitive function?
00:52:01.200 Because that'd be
00:52:01.860 the fastest way to test
00:52:02.920 whether that was helpful.
00:52:04.220 Yeah, so as a clinician,
00:52:05.540 you'll appreciate this.
00:52:07.340 But as a biomedical scientist,
00:52:08.900 I sort of am frustrated
00:52:10.140 by the lack of other studies,
00:52:12.060 but the number of case reports
00:52:13.720 that are being published
00:52:14.720 just keeps climbing,
00:52:16.380 climbing, climbing.
00:52:17.040 That the brain,
00:52:18.000 as it becomes insulin resistant
00:52:19.380 and it can't get
00:52:20.120 as much glucose,
00:52:21.300 it's like the rhyme
00:52:22.120 of the ancient Mariner.
00:52:23.160 It's this sort of metabolic,
00:52:25.120 this version of it
00:52:26.060 where even if the body's
00:52:27.400 hyperglycemic,
00:52:28.500 if the brain is insulin resistant,
00:52:29.960 it's basically crying out,
00:52:32.480 glucose, glucose everywhere,
00:52:33.840 nor not a drop to drink.
00:52:35.180 Right, right.
00:52:35.460 It can't use that glucose
00:52:36.740 because it's insulin resistant
00:52:38.460 and it needs insulin
00:52:39.300 to help open the doors
00:52:40.260 to get the glucose in.
00:52:41.200 Yeah, yeah.
00:52:41.720 But the ketones are unregulated.
00:52:43.660 So to the case reports,
00:52:45.260 yes, there are documented,
00:52:47.020 peer-reviewed instances
00:52:48.240 where you can take a patient
00:52:50.020 whose cognition
00:52:50.780 is so compromised
00:52:51.660 they can't tie their shoelaces
00:52:53.620 or they can't draw out
00:52:55.300 the face of an analog clock.
00:52:57.740 Yeah, yeah.
00:52:58.000 You'll give them
00:52:58.340 a piece of paper and a pen,
00:52:59.760 draw out the clock,
00:53:00.780 one, two, three, and so on.
00:53:02.460 Put them into ketosis,
00:53:04.060 have them do those tests again.
00:53:05.920 They can tie their shoes.
00:53:07.480 They can draw the face.
00:53:08.320 That quickly.
00:53:08.700 It's still a little
00:53:09.340 within hours.
00:53:10.820 Jesus.
00:53:11.000 Within hours.
00:53:11.960 I wonder if anybody's tried that
00:53:13.420 with 45-year-olds
00:53:15.160 for fluid IQ tests
00:53:17.180 because that'd be
00:53:18.400 a quick test, right?
00:53:19.480 I would think so.
00:53:20.240 Take the same people.
00:53:21.160 I should talk to Michaela
00:53:22.180 about that
00:53:22.620 because we could do
00:53:23.120 that study really quick.
00:53:24.380 Take 50-year-old people.
00:53:25.800 Ah, take obese
00:53:27.820 50-year-old people.
00:53:28.880 Now you're talking.
00:53:30.480 Do a fluid IQ test,
00:53:31.940 put them in ketosis,
00:53:33.260 which would take
00:53:33.920 like 48 hours.
00:53:35.040 Yeah, about that.
00:53:36.040 Or nowadays,
00:53:36.500 you can drink ketones
00:53:37.540 for goodness sakes.
00:53:38.780 They've become
00:53:39.480 so obviously beneficial.
00:53:41.160 My university
00:53:42.020 just won the
00:53:42.660 cross-country national championship.
00:53:43.800 Well, how fast could you
00:53:44.480 put someone into ketosis?
00:53:45.520 Within an hour,
00:53:46.380 depending on what you're drinking.
00:53:46.900 So you could bring them
00:53:47.600 in for one day.
00:53:48.800 You could give them
00:53:49.340 fluid IQ test,
00:53:51.180 put them into ketosis,
00:53:52.180 and give the test again.
00:53:53.540 Yeah, you could even swap,
00:53:54.540 do it sort of placebo.
00:53:55.400 Yeah, yeah, right.
00:53:55.960 Because one day after another,
00:53:57.020 you're drinking something,
00:53:57.940 then you're drinking ketones.
00:53:58.400 Do you want to do that?
00:53:59.660 Let's do it.
00:54:00.580 That's the beauty
00:54:01.080 of basic science.
00:54:01.960 We could fund that.
00:54:02.860 Well, the brain thrives
00:54:04.720 on ketones.
00:54:05.520 My own lab,
00:54:06.740 we've published reports
00:54:07.800 documenting how
00:54:08.700 when a person's in ketosis,
00:54:09.980 we actually had people
00:54:10.840 and we were pulling
00:54:11.340 fat biopsies from their belly,
00:54:13.100 little pieces of fat,
00:54:14.140 taking it to my lab
00:54:15.000 and testing the metabolic rate.
00:54:16.820 The metabolic rate
00:54:17.480 went up three times.
00:54:19.840 As soon as they're in ketosis.
00:54:20.620 As soon as they're in ketosis.
00:54:21.620 The fat tissue just starts.
00:54:23.040 It basically signals
00:54:24.320 when ketones are up,
00:54:26.040 insulin's down,
00:54:27.120 it's sort of party time
00:54:28.600 with metabolism.
00:54:29.720 It's let's just get moving stuff.
00:54:31.280 Metabolic rate goes up.
00:54:32.680 Autophagy turns on.
00:54:34.440 Things.
00:54:35.100 That quickly.
00:54:35.940 Oh, yeah.
00:54:36.200 Okay, so how would you put someone
00:54:37.800 in a state of ketosis
00:54:38.760 with a drink?
00:54:39.780 Yeah, so.
00:54:40.240 How do you do that?
00:54:41.000 There are multiple different,
00:54:42.580 now ketones have become
00:54:43.800 so obviously beneficial.
00:54:45.880 It increases metabolic rate.
00:54:47.460 It helps people
00:54:48.120 physically perform better.
00:54:49.320 Race car drivers to it,
00:54:50.700 take it.
00:54:51.180 Tour de France athletes take it.
00:54:53.200 Cross-country athletes take it.
00:54:54.720 It's a viable fuel.
00:54:56.420 So as ketones have become
00:54:57.540 more and more accepted
00:54:58.760 for all their benefits,
00:54:59.880 there's been a bit of a race
00:55:01.780 to say,
00:55:02.960 all right,
00:55:03.100 well, how can we do this best?
00:55:04.140 And there are multiple
00:55:05.160 different versions
00:55:05.900 from the lesser effective
00:55:08.420 but much cheaper
00:55:09.500 things called ketone salts.
00:55:11.840 Then you go through
00:55:13.160 the ketone esters
00:55:14.740 and then you get
00:55:15.280 the bioidentical ketones.
00:55:17.320 And they're all
00:55:18.320 of kind of varying efficacy.
00:55:19.960 As they get more effective,
00:55:21.040 the price goes up.
00:55:22.260 But I'll say,
00:55:24.300 having seen my beloved Baba,
00:55:26.720 my grandma up in Alberta,
00:55:28.080 die from Alzheimer's disease,
00:55:30.240 it is so terrifying
00:55:31.860 that one of the reasons
00:55:33.360 I adhere to my own
00:55:35.280 low-carbohydrate diet
00:55:36.520 is because I want to keep
00:55:38.400 my brain as healthy as possible.
00:55:40.100 Yeah, yeah.
00:55:40.560 The fact that I stay lean
00:55:41.800 and healthy,
00:55:42.380 well, that's just a plus.
00:55:44.340 That's, well,
00:55:44.780 even my fear of cancer.
00:55:46.320 Cancer cells don't use ketones,
00:55:48.040 they use glucose.
00:55:49.300 And so all the more reason
00:55:50.360 to keep my glucose in check.
00:55:52.040 Yeah, and so with regards
00:55:53.260 to that specifically,
00:55:55.140 so are there studies
00:55:57.640 indicating a decrease
00:56:00.820 in the rate of cancer propagation
00:56:02.760 on zero-carb diets?
00:56:06.000 Yeah.
00:56:06.460 And are they case studies?
00:56:07.440 Yeah, no,
00:56:07.720 so that's a really good question.
00:56:09.000 And I'm going to respect
00:56:09.840 how you framed it,
00:56:10.840 which is,
00:56:11.720 can you prevent the cancer?
00:56:13.380 That's not been,
00:56:14.100 there's no paper on that.
00:56:15.460 What there are papers on
00:56:16.600 is looking at untreatable,
00:56:18.400 particularly brain tumors.
00:56:19.600 This is where most of the research
00:56:20.620 is at the moment.
00:56:21.220 At Boston University,
00:56:22.540 they are absolutely
00:56:23.480 leading the charge on this.
00:56:25.220 One of the most effective therapies
00:56:26.660 they're doing
00:56:27.180 is putting them into deep ketosis.
00:56:29.400 If they have
00:56:29.840 an inoperable brain tumor.
00:56:31.000 Yes, and it can take
00:56:31.580 an inoperable brain tumor
00:56:32.740 and not only stop it
00:56:33.740 in its tracks,
00:56:34.400 but literally start to shrink it.
00:56:35.480 And is the shrinkage
00:56:36.500 a consequence of autophagy?
00:56:38.680 Well, yeah, absolutely.
00:56:39.640 So, yeah,
00:56:40.160 so coming back to a topic
00:56:41.300 you mentioned earlier,
00:56:42.560 certainly it's part of autophagy
00:56:44.400 and probably just
00:56:45.340 good old-fashioned necrosis.
00:56:47.100 You simply are dying
00:56:48.120 because you can't survive.
00:56:49.880 Cancer cells
00:56:50.560 will metabolize,
00:56:52.240 they rely on glucose
00:56:53.160 as their main fuel
00:56:54.140 because it's a quick burning fuel.
00:56:55.600 And they propagate rapidly.
00:56:56.860 Right, so they're more
00:56:58.000 dependent on glucose
00:56:59.040 than ordinary cells.
00:57:00.200 And they don't want to have
00:57:01.000 to rely on blood flow
00:57:02.300 where they basically
00:57:04.000 are growing so quick
00:57:05.020 that they outpace
00:57:06.020 the blood flow.
00:57:07.020 And glucose doesn't need
00:57:08.400 oxygen to burn.
00:57:09.580 It can be fermented.
00:57:11.260 But just to really elaborate
00:57:13.060 how clever this area
00:57:14.420 of research is,
00:57:15.320 this group at Boston,
00:57:18.360 they took a tumor cell
00:57:19.760 and the whole theory
00:57:21.600 of cancer is that
00:57:22.360 it's genes,
00:57:23.060 it's from your nucleus.
00:57:24.600 Yeah, right.
00:57:25.000 It's a nuclear genetic disease.
00:57:26.880 And yet they took the nucleus
00:57:28.100 from a tumor cell
00:57:29.220 and put it into a healthy cell
00:57:31.320 and the cell was totally normal.
00:57:32.920 It didn't do anything.
00:57:33.580 They literally transplanted
00:57:34.760 the genetics.
00:57:36.540 Now,
00:57:37.420 what they also did
00:57:38.720 was take the mitochondria,
00:57:40.320 the powerhouse of the cell.
00:57:41.960 That's where you're burning
00:57:42.780 the ketones and the fats.
00:57:44.460 Then they put the mitochondria
00:57:45.800 from the tumor cell
00:57:46.900 into a healthy cell.
00:57:48.940 It had cancer.
00:57:49.880 It became a cancer cell.
00:57:51.620 So they're changing
00:57:52.680 the entire paradigm of cancer
00:57:54.320 saying that it's not a genetic problem.
00:57:55.240 So are the cells adapted
00:57:56.460 to glucose metabolism?
00:57:57.740 Oh, yes.
00:57:58.040 Are cancer cells adapted
00:57:59.080 to glucose metabolism?
00:58:00.300 And if you force them
00:58:01.360 to rely on something
00:58:02.600 other than glucose,
00:58:04.120 they die.
00:58:04.880 It's incompatible
00:58:05.920 with their rate of growth
00:58:06.860 and they can't sustain it.
00:58:09.140 So ketones are at the front.
00:58:10.040 See, I've also read
00:58:11.020 that if you're undergoing
00:58:12.360 radiation therapy,
00:58:13.780 for example,
00:58:14.440 or what's the chemical treatment?
00:58:18.720 Chemotherapy.
00:58:19.140 Chemotherapy.
00:58:19.740 Yeah.
00:58:20.080 More specifically,
00:58:21.060 chemotherapy,
00:58:22.020 that if you put yourself
00:58:23.220 into ketosis,
00:58:24.860 you have much less,
00:58:28.820 you have much modified
00:58:31.620 negative reaction
00:58:32.620 to the chemotherapy.
00:58:34.160 Yep.
00:58:34.400 In fact,
00:58:34.720 that is...
00:58:35.020 Much less...
00:58:36.120 Yes.
00:58:36.400 The negative side effect.
00:58:37.620 Yeah, yeah.
00:58:37.920 When you think about chemotherapy,
00:58:39.080 it really is a matter
00:58:41.080 of the oncologist,
00:58:44.260 the cancer physician
00:58:44.960 saying,
00:58:45.460 how much poison
00:58:46.280 can I give you?
00:58:46.580 Can I give you?
00:58:47.300 Yeah, yeah.
00:58:47.660 So that you,
00:58:48.620 enough of you survives,
00:58:49.980 but I kill what we don't want,
00:58:51.720 namely the cancer.
00:58:52.820 So chemotherapy
00:58:53.360 is a miserable way to go.
00:58:57.740 And I have my own
00:58:59.220 strong thoughts
00:58:59.940 on the very field
00:59:01.160 of oncology
00:59:01.700 and the use of chemotherapeutics.
00:59:03.080 I think by and large,
00:59:03.840 most of them
00:59:04.420 are not worth...
00:59:06.800 The trouble.
00:59:07.100 Not worth the trouble.
00:59:08.220 Right.
00:59:08.440 You maybe will live
00:59:09.540 another week,
00:59:10.180 if anything,
00:59:11.040 and you will have
00:59:11.460 bankrupted your entire
00:59:12.420 family doing so.
00:59:14.060 Right.
00:59:14.580 But even back
00:59:15.580 to the glioblastoma,
00:59:16.700 the inoperable
00:59:17.280 brain tumor area,
00:59:18.400 part of what they've shown
00:59:19.420 is that ketogenic diets
00:59:20.540 can act as a kind
00:59:21.520 of adjuvant therapy.
00:59:22.720 Right.
00:59:23.060 That the actual amount
00:59:23.920 of dose
00:59:24.420 of the chemotherapy
00:59:25.300 required...
00:59:25.900 Can be much lower.
00:59:26.400 ...is much, much lower
00:59:27.400 and far more effective.
00:59:27.680 Right, because you're
00:59:27.980 already compromising
00:59:28.780 the tissue.
00:59:29.220 You're already killing them.
00:59:30.400 Right.
00:59:30.660 Now you're just pushing
00:59:31.380 them over the edge.
00:59:32.760 I mean,
00:59:33.020 this is so much...
00:59:33.800 This is why I beat
00:59:34.580 this drum so loudly
00:59:35.480 that you look at...
00:59:37.440 At the end of this
00:59:38.720 conversation,
00:59:39.840 one of my great hopes
00:59:41.180 is that someone listening
00:59:42.540 opens up their
00:59:43.200 morning medicine cabinet
00:59:44.300 and they take out
00:59:45.500 their two medications
00:59:46.340 for their diabetes.
00:59:47.360 They take out their
00:59:47.960 medication for their
00:59:48.760 blood pressure.
00:59:49.560 They take out their
00:59:50.380 medication for their
00:59:51.300 PCOS or their
00:59:52.260 erectile dysfunction,
00:59:53.580 thinking,
00:59:54.660 because there's
00:59:55.200 different pills,
00:59:55.880 these are different
00:59:56.480 problems.
00:59:56.940 Right, right, right.
00:59:57.420 And yet,
00:59:57.860 if they start to
00:59:58.700 institute just the
01:00:00.540 simplest,
01:00:01.600 albeit not easy,
01:00:02.680 but the simplest
01:00:03.320 lifestyle changes
01:00:04.480 to start correcting
01:00:05.680 the glucose,
01:00:06.520 correcting the insulin,
01:00:07.580 they'll find,
01:00:08.380 much to their delight,
01:00:09.600 that those medications
01:00:10.360 can just stay in the
01:00:11.360 medicine cabinet.
01:00:12.080 Right, right.
01:00:12.180 They're correcting
01:00:13.360 their problem
01:00:13.980 one at a time.
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01:00:22.380 Can someone please
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01:01:15.900 Okay, so let's
01:01:20.360 go back to the
01:01:21.040 beginning of the
01:01:21.820 conversation and
01:01:22.600 just summarize.
01:01:23.360 So what we were
01:01:24.600 attempting to do
01:01:25.480 right off the bat
01:01:26.920 with regards to
01:01:28.060 the Maha movement
01:01:29.200 was to focus on
01:01:31.180 the Pareto
01:01:32.980 distribution,
01:01:33.920 bang for the
01:01:34.500 buck.
01:01:34.880 It's right,
01:01:35.220 where's the
01:01:35.680 biggest criminal?
01:01:36.760 Let's stop that
01:01:37.900 and maybe we don't
01:01:38.640 have to worry about
01:01:39.360 anything else and
01:01:40.520 maybe we could
01:01:41.040 stop one thing
01:01:42.240 and what would
01:01:42.920 that be?
01:01:44.120 Well, you talked
01:01:44.940 about insulin
01:01:45.600 resistance and
01:01:46.360 then we tied that
01:01:47.060 to diet.
01:01:47.820 That's high carb,
01:01:48.820 high sugar diets
01:01:49.680 cause insulin
01:01:50.700 resistance.
01:01:51.560 Well, then what
01:01:52.140 does that cause?
01:01:53.580 Well, it causes
01:01:54.700 insulin resistance,
01:01:55.660 causes obesity,
01:01:56.580 which also causes
01:01:57.660 insulin resistance
01:01:58.620 and then insulin
01:01:59.840 resistance has a
01:02:00.820 cascade of effects.
01:02:02.540 One of them,
01:02:03.440 well, erectile
01:02:04.140 dysfunction is one
01:02:04.980 of them.
01:02:06.060 Alzheimer's is one
01:02:06.920 of them.
01:02:07.380 Cancer is one
01:02:08.080 of them.
01:02:08.460 High blood
01:02:08.900 pressure, heart
01:02:09.800 disease.
01:02:10.440 These are very
01:02:11.840 bad things.
01:02:12.540 Oh, yeah, the
01:02:12.960 biggest.
01:02:13.460 Of the bad.
01:02:14.060 Right, right,
01:02:14.580 right, right.
01:02:15.080 So we're really
01:02:15.640 at the root of
01:02:17.500 the cause of
01:02:18.300 the so-called
01:02:19.580 multiplicity of
01:02:20.500 negative consequences.
01:02:22.500 Yeah, and you
01:02:22.860 said root.
01:02:24.380 And so much of,
01:02:25.680 so conventional
01:02:26.660 medicine is giving
01:02:27.900 medications, which
01:02:29.100 is trimming at the
01:02:29.760 branches, only to
01:02:31.200 have them grow back.
01:02:32.020 Well, let's just
01:02:32.460 chop the damn
01:02:33.180 tree down and to
01:02:34.560 do so, you've got
01:02:35.420 to go right to the
01:02:36.020 soil, which is
01:02:36.740 lifestyle.
01:02:37.360 Yeah, so you said
01:02:37.960 go to the root.
01:02:39.080 There is a root
01:02:39.960 problem and no
01:02:41.280 medication is going
01:02:42.040 to address it.
01:02:42.620 Right, right,
01:02:43.340 right, right.
01:02:44.160 Well, the
01:02:44.760 medication is going
01:02:45.680 to work if you
01:02:46.440 keep consuming
01:02:47.140 exactly what's
01:02:48.020 causing the
01:02:48.920 multitude of
01:02:49.540 problems.
01:02:49.800 And even if it
01:02:50.440 addresses one of
01:02:51.220 your symptoms, like
01:02:53.060 erectile dysfunction
01:02:53.820 pill, that doesn't
01:02:55.020 mean it's going to
01:02:55.580 address the fact that
01:02:56.920 your diet is making
01:02:58.420 you prone to
01:02:58.960 Alzheimer's.
01:02:59.640 That's right.
01:03:00.160 Right, right.
01:03:00.700 Okay.
01:03:01.160 And it's only
01:03:01.640 putting a band-aid
01:03:02.980 on.
01:03:03.320 Right.
01:03:03.440 Like any
01:03:03.740 medication.
01:03:04.260 When it comes to
01:03:04.760 metabolic problems,
01:03:06.020 no medication can
01:03:07.080 solve the problem.
01:03:08.020 It will just mask
01:03:08.960 it, which is why
01:03:09.680 something as
01:03:10.840 reversible as
01:03:11.540 type 2 diabetes.
01:03:12.020 One dimension of
01:03:12.640 it.
01:03:12.780 Yeah, one aspect.
01:03:14.120 So something as
01:03:14.980 easily reversible as
01:03:16.320 type 2 diabetes, a
01:03:17.380 disease of too much
01:03:18.100 insulin, bring your
01:03:19.100 insulin down, eat
01:03:19.940 less carbs.
01:03:20.960 The traditional view
01:03:22.340 would be to say, and
01:03:23.240 the clinician will say
01:03:24.100 this, type 2 diabetes
01:03:24.980 is irreversible.
01:03:26.360 Yeah.
01:03:26.800 Because if you treat
01:03:27.620 it with conventional
01:03:28.280 means, it is.
01:03:29.460 You will never get off
01:03:30.560 those drugs.
01:03:31.300 The dose will go up.
01:03:32.420 You'll have more
01:03:32.980 drugs, more and more
01:03:33.740 drugs, because you're
01:03:34.820 not actually solving
01:03:35.660 the problem.
01:03:36.600 Type 2 diabetes is
01:03:38.140 absolutely reversible.
01:03:40.240 It's just you have to
01:03:41.000 respect that it's food.
01:03:42.440 The food we eat is the
01:03:43.480 culprit or the cure.
01:03:44.880 Okay, so let's talk
01:03:45.960 about lifestyle
01:03:47.040 modification.
01:03:47.960 Yeah.
01:03:48.400 Okay, so I want to
01:03:51.340 talk about two things.
01:03:52.280 I want to talk about
01:03:53.220 government subsidy,
01:03:55.360 let's say, and the
01:03:57.360 food pyramid, the
01:03:58.240 original food pyramid,
01:03:59.320 and how it was
01:03:59.880 developed, because
01:04:00.900 there's a story that
01:04:01.780 will curl your hair.
01:04:03.200 Oh, it's so, it's
01:04:04.320 so appalling.
01:04:05.100 Oh, it's vile.
01:04:05.420 It's so appalling.
01:04:06.760 It's just, you can't
01:04:08.000 read that without, what
01:04:09.700 would you say?
01:04:10.620 It's like a traumatic
01:04:11.680 loss of naivety to
01:04:13.560 believe that something
01:04:14.480 that catastrophic could
01:04:16.760 have been consciously
01:04:17.720 perpetrated, yet it was.
01:04:19.940 It was.
01:04:20.440 It's unbelievable.
01:04:21.340 It's unbelievable.
01:04:22.620 Okay, so lifestyle
01:04:25.540 change.
01:04:26.160 So we think of the
01:04:26.900 typical supermarket,
01:04:28.320 okay?
01:04:28.680 Yes.
01:04:28.980 People have often
01:04:29.840 been counseled to eat
01:04:31.940 around the edges,
01:04:33.700 right?
01:04:33.840 Don't go in the
01:04:34.360 middle of the
01:04:34.700 supermarket.
01:04:35.620 Why?
01:04:36.380 Because that's where
01:04:37.200 all the processed food
01:04:38.480 is.
01:04:39.020 Well, is the problem
01:04:39.980 processing?
01:04:41.000 I don't think the
01:04:41.860 problem is processing.
01:04:43.020 The problem is all
01:04:43.840 processed foods are
01:04:45.080 emergency, hypercaloric,
01:04:47.900 glucose-centric foods.
01:04:50.660 Right, so they should
01:04:51.400 be, they're there like
01:04:53.120 when you come across a
01:04:54.060 beehive.
01:04:54.580 They're not to eat
01:04:55.280 every day.
01:04:55.980 So you go around the
01:04:57.280 edges and you eat,
01:04:58.480 and you tell me if you
01:04:59.320 disagree with any of
01:05:00.200 this, because we want
01:05:01.100 to make it simple for
01:05:01.960 people, right?
01:05:03.080 So you stay away from
01:05:04.280 the processed foods
01:05:05.060 because they're too
01:05:05.860 high in concentrated
01:05:07.040 carbohydrate and sugar.
01:05:08.700 Yes.
01:05:09.280 Fundamentally.
01:05:09.880 Now, there may be
01:05:10.460 other reasons to
01:05:11.240 avoid them as well.
01:05:12.180 Yeah.
01:05:12.960 The chemicals that
01:05:13.860 are in them, the
01:05:14.760 fact that they've been
01:05:15.640 designed to be
01:05:16.320 addictive, etc.
01:05:17.920 Oh, yes.
01:05:18.300 But to me, that's
01:05:19.060 trivial compared to
01:05:20.100 the fact that, no,
01:05:21.260 mostly they're just the
01:05:22.660 equivalent of sugar.
01:05:23.760 Yep.
01:05:23.920 Okay, now you graze
01:05:26.200 around the edges.
01:05:26.920 That means the kinds
01:05:28.760 of vegetables you don't
01:05:29.600 really like, right?
01:05:31.300 Yeah.
01:05:32.320 Dairy, including butter,
01:05:34.920 including yogurt, all of
01:05:35.860 that.
01:05:36.460 So that's food that
01:05:37.760 people actually like.
01:05:38.940 Yeah.
01:05:39.320 Not sweetened yogurt,
01:05:40.980 no sugar.
01:05:41.880 Stay away from the
01:05:42.480 damn sugar.
01:05:43.320 Yeah.
01:05:43.960 Meat.
01:05:45.160 And that's about that
01:05:46.500 fundamentally, right?
01:05:48.020 Yes.
01:05:48.260 And definitely don't
01:05:49.100 drink soft drinks.
01:05:50.120 No, no.
01:05:50.780 Absolutely, yeah.
01:05:51.680 I mean, you don't want
01:05:52.720 your food to come from,
01:05:53.840 the less you are able to
01:05:54.960 formulate a diet,
01:05:55.820 where your food isn't
01:05:57.060 coming from bags and
01:05:58.060 boxes with barcodes,
01:05:59.280 the better off you're
01:06:00.280 going to be.
01:06:00.920 And the way you just
01:06:01.660 described it, you've
01:06:02.800 done it.
01:06:03.320 To me, I mean, first
01:06:05.420 and foremost, we are,
01:06:08.260 we have more in common
01:06:09.620 with a wolf,
01:06:11.400 digestively speaking,
01:06:12.600 than we do our
01:06:13.340 closest, closest animal
01:06:15.360 relative like chimpanzees
01:06:17.060 or apes or any other
01:06:18.400 primate.
01:06:19.360 If you look at the
01:06:20.260 digestive system.
01:06:20.980 Chimps spend eight
01:06:21.920 hours a day chewing.
01:06:23.320 Yeah, they have to eat
01:06:24.340 constantly because they
01:06:25.580 have, it is such a
01:06:26.640 nutrient deficient diet.
01:06:28.340 Their colon, their large
01:06:29.440 intestine is substantially
01:06:30.860 bigger than the humans
01:06:32.240 because they have to
01:06:32.780 ferment so much.
01:06:33.920 Moreover.
01:06:33.980 Yes, and brain
01:06:34.680 comparatively smaller.
01:06:35.540 Very small brain,
01:06:36.460 very big intestines.
01:06:37.640 Yes, yes, yes.
01:06:38.080 And even still.
01:06:39.020 That's the vegan
01:06:39.580 evolutionary pathway, by the
01:06:41.360 way, yeah.
01:06:41.960 Yeah, and you want to
01:06:42.540 shrink your brain, remove
01:06:44.240 animal sourced foods from
01:06:45.500 it, and you'll, yes, you'll
01:06:46.320 be like your other primate
01:06:47.540 cousins and start to shrink
01:06:48.640 your brain.
01:06:49.180 But unfortunately, you don't
01:06:50.880 have the colon to ferment as
01:06:52.700 much as they do.
01:06:53.220 Moreover, you're probably
01:06:54.800 not prepared to eat your
01:06:56.020 own feces, which is what
01:06:58.100 they'll do to get vitamin
01:06:59.360 B12.
01:07:00.500 A purely plant-based diet is
01:07:02.600 so deficient in nutrients,
01:07:04.300 it is utterly incompatible
01:07:05.740 with the human survival, let
01:07:08.020 alone human reproduction.
01:07:10.280 I consider it, in fact, I feel
01:07:11.760 so strongly about this that I
01:07:13.120 actually consider it to be quite
01:07:14.480 devilish or overtly satanic that
01:07:17.020 I think of, if you'll allow me to
01:07:18.880 invoke some scripture, we often
01:07:20.900 talk about Christ's great
01:07:22.120 commandments, love God, love
01:07:23.860 your neighbor, and yet there
01:07:25.640 was a commandment that
01:07:26.500 preceded those, which was God's
01:07:28.500 commandment to Adam and Eve,
01:07:29.860 be fruitful, multiply and
01:07:31.460 replenish the earth.
01:07:32.140 That was the first commandment.
01:07:34.520 And the older I'm getting, as
01:07:35.700 both a man of religion and of
01:07:37.460 science, I sort of use that
01:07:39.640 commandment as my litmus test.
01:07:41.800 If this is an ideology or a
01:07:43.560 principle or a practice that is
01:07:44.740 going to make it harder for
01:07:45.720 people to reproduce, then there's
01:07:48.120 something fundamentally wrong with it,
01:07:50.060 and I must reject it.
01:07:51.380 And so, even when it comes to
01:07:52.540 diet...
01:07:52.780 Well, reproductive capacity is
01:07:54.440 species health across generations,
01:07:57.240 right?
01:07:57.400 It's the equivalent of health,
01:07:58.580 except across generations.
01:08:00.540 So, obviously, anything that's
01:08:02.480 anti-reproduction in its essence
01:08:04.760 is, there isn't anything more
01:08:07.200 pathological than that.
01:08:07.540 Whether you invoke God, whether
01:08:09.480 the commandment to Adam and
01:08:10.480 Eve, or whether you invoke
01:08:11.340 evolution, whose great design is
01:08:14.000 to just have an advantage to
01:08:15.180 reproduce, you all come back to
01:08:17.360 reproduction.
01:08:17.860 See, one of the things I'm
01:08:19.960 seeing on the Maha side is that
01:08:22.480 it's difficult to bring unity to
01:08:25.780 the field of preventative
01:08:28.280 medicine.
01:08:29.280 I mean, many people are
01:08:30.540 concentrating on the panoply of
01:08:33.380 chemicals that are in, like,
01:08:35.100 Fruit Loops.
01:08:35.880 And fair enough.
01:08:36.900 Fair enough.
01:08:37.240 Fair enough.
01:08:37.860 But, for me, the problem with a
01:08:40.620 Fruit Loop is that it's basically
01:08:41.900 just a sugar lump.
01:08:43.280 Oh, you and I are totally aligned
01:08:44.840 on this.
01:08:45.240 Okay, okay.
01:08:45.580 You have to manage your macros.
01:08:47.200 All the other micro stuff, yeah,
01:08:49.000 that matters a little, but if
01:08:50.480 your macronutrients aren't
01:08:51.540 aligned, carbohydrates, proteins,
01:08:53.280 fats, and I have rules for each
01:08:54.940 of them, then all that other
01:08:56.380 stuff is fluff.
01:08:57.200 Yeah, it's noise, essentially.
01:08:58.220 It's noise.
01:08:58.960 Yeah, well, that's right.
01:08:59.360 We'll move the needle a little,
01:09:00.260 but not enough to do anything.
01:09:01.060 Yeah, yeah, yeah.
01:09:01.260 Well, so, and then the thing is,
01:09:02.580 if you're only able to fight one
01:09:04.180 battle at a time, you better fight
01:09:05.500 the right battle.
01:09:06.360 That's right.
01:09:06.800 And it seems to me.
01:09:07.560 Now, it's also the case that
01:09:09.060 there's no recommended daily
01:09:10.500 allowance for carbohydrates.
01:09:12.540 Yeah, oddly enough.
01:09:13.360 I know, that's very odd.
01:09:15.140 So expand on what that means.
01:09:16.300 Yeah, so it's odd for multiple
01:09:17.420 reasons, including I consider it
01:09:18.960 the most pathogenic because of
01:09:20.340 everything we've been describing,
01:09:21.720 but it's also the one that is
01:09:23.360 utterly unessential.
01:09:25.120 You appreciate this, but most
01:09:26.340 people don't.
01:09:27.020 Even within the United States,
01:09:29.720 the Department of Agriculture
01:09:30.820 years ago had a statement where
01:09:32.600 it says something like, I'm going
01:09:33.840 to loosely quote it, the lower
01:09:35.460 limit of dietary carbohydrates is
01:09:37.740 zero.
01:09:38.940 Right.
01:09:39.800 Zero is a low limit, man.
01:09:41.200 Yeah, that's a pretty low number.
01:09:42.380 That's for sure.
01:09:43.260 And yet, that's the one you tell
01:09:44.440 me to eat the most of, born from
01:09:46.380 the food guide pyramid and its
01:09:47.960 ill-fated ideology, or born from
01:09:50.640 the modern obsession, sort of a
01:09:52.660 pseudo-religious view that we can't
01:09:54.580 kill anything, and what a naive view.
01:09:56.660 Life is death.
01:09:57.780 Everything that is alive benefits
01:09:59.060 because something died before it,
01:10:00.980 and we benefit from all of that
01:10:02.500 stuff.
01:10:03.040 So, we have this kind of perverse
01:10:06.000 shifted view of nutrition where
01:10:09.580 we focus on carbohydrates.
01:10:12.320 The one thing we don't, we literally
01:10:14.620 don't need to eat it.
01:10:15.880 There's no such thing as an essential
01:10:17.420 carbohydrate, and yet 70% of all
01:10:19.860 calories globally come from
01:10:21.200 carbohydrates.
01:10:22.160 They do have the advantage of being
01:10:24.320 cheap in the short run.
01:10:26.360 Yeah.
01:10:26.860 Especially if it's subsidized, it's
01:10:28.560 cheap for the person who's purchasing it.
01:10:28.980 Yeah, well, that's a separate issue.
01:10:30.440 Like, because you could imagine, you
01:10:32.260 know, humanity's been solving a
01:10:34.120 sequence of problems, and once, one
01:10:36.140 problem, and it was real, was there
01:10:38.080 just wasn't enough calories.
01:10:40.620 Okay, so you probably want to address
01:10:42.140 that so people don't starve, and fair
01:10:44.240 enough, and maybe you can address that
01:10:45.820 more cheaply with corn than with beef.
01:10:50.760 Okay, and so there, we've given the
01:10:53.360 devil his stew, but that doesn't mean
01:10:55.980 that that constitutes an optimized diet,
01:10:58.020 and that's where I think the people who
01:10:59.900 created the food pyramid were criminal.
01:11:01.700 Oh, criminal.
01:11:02.680 Yeah.
01:11:02.900 Because the story, and this is a story
01:11:06.340 you're fleshing out, is that the base
01:11:08.260 of the pyramid, so that's where you get
01:11:09.800 the bulk of your calories, according to
01:11:14.240 the hypothetically scientific guidelines
01:11:17.200 of the government, which were never
01:11:19.000 scientific in the least, right from the
01:11:20.960 beginning, is that that's where you
01:11:22.400 should derive the bulk of your calories.
01:11:23.980 Yes.
01:11:24.220 And then fats and meat are a tiny, tiny
01:11:27.820 element of that.
01:11:28.380 Yeah, no, no.
01:11:28.880 And that's, it's, they knew from what
01:11:30.940 I've been able to, from what I've seen
01:11:33.860 in my investigations, is that the people
01:11:36.300 who designed that bloody pyramid were
01:11:37.820 told by their own scientists that they
01:11:40.660 were going to produce an epidemic of
01:11:42.700 obesity and diabetes.
01:11:44.260 Yeah, Dr.
01:11:45.140 Philip Handler was the president of one
01:11:47.120 of the leading scientific societies in the
01:11:48.860 United States at the time, and I'm going to
01:11:50.440 loosely quote him, but he says, what right
01:11:52.040 has the federal government to conduct such
01:11:54.160 a grand experiment with the population
01:11:56.840 of the United States as its test
01:11:58.340 subjects that it had never been done?
01:12:00.320 With no control.
01:12:01.200 No, that's right.
01:12:01.800 It had never been done.
01:12:02.660 And no consent.
01:12:03.400 And look at what's happened.
01:12:04.740 People want to blame meat for all what
01:12:06.900 ills us, which talk about an insane
01:12:08.920 ideology, but you look at red meat
01:12:11.020 consumption from the early 1900s till
01:12:12.980 now, it's been a steady decline.
01:12:15.800 And yet what's happened to heart disease,
01:12:17.340 even at the superficial 30,000 foot view,
01:12:20.800 blaming meat for the ills of the modern,
01:12:23.940 these diseases of civilization, these
01:12:25.580 plagues of prosperity, it makes no sense.
01:12:28.080 Well, now we've got the bloody greens
01:12:29.980 who are doing the same thing.
01:12:31.360 And, you know, the globalist utopian
01:12:34.300 vision, this is the C40 vision.
01:12:37.180 This is a consortium of municipalities all
01:12:39.320 around the world, including many of the
01:12:41.040 world's biggest cities.
01:12:42.040 They want a 95% reduction in meat
01:12:45.440 consumption.
01:12:46.380 That's not all.
01:12:48.120 95% reduction in private automobile
01:12:50.320 ownership.
01:12:50.980 Oh, yes, of course.
01:12:51.780 A one short haul flight per person every
01:12:55.000 three years.
01:12:55.780 Oh, my.
01:12:56.160 Three items of clothing per year.
01:12:58.400 That sounds like a perfect way to
01:12:59.720 enslave people.
01:13:00.500 Oh, it's just beyond comprehension.
01:13:01.920 But the meat element is particularly egregious,
01:13:04.800 as far as I'm concerned, because there are
01:13:06.540 forms of agriculture that are meat intensive,
01:13:10.340 that revivify soil.
01:13:12.100 Oh, yes.
01:13:12.440 And the idea that that's contributing to
01:13:13.900 something like a climate catastrophe,
01:13:15.460 that I can't imagine a stupider lie than that one.
01:13:17.900 No, no.
01:13:18.060 Although there are some.
01:13:19.360 It is.
01:13:19.700 It is tragic because for multiple reasons,
01:13:22.020 just as a fun aside, when men, studies in men
01:13:25.220 have shown that if man stops eating meat,
01:13:27.660 saturated fats in particular, his testosterone
01:13:29.980 plummets, his sperm production plummets.
01:13:32.400 Like, this is antithetical to human production.
01:13:34.780 Well, wouldn't you think that that's an evolution,
01:13:36.500 that's a biological sign of scarcity?
01:13:38.460 Yes, that's right.
01:13:39.140 Well, it's no bloody wonder that you're-
01:13:40.300 Don't reproduce.
01:13:41.140 Don't reproduce now because all you have to
01:13:42.740 eat is broccoli.
01:13:43.740 Yeah.
01:13:44.060 Right.
01:13:44.880 Yeah, that's right.
01:13:45.440 It's a sobering view, which is,
01:13:47.640 when you look at the Food Guide Pyramid,
01:13:49.260 one of the, like, literal authors of the Food
01:13:51.800 Guide Pyramid wrote this and proposed it,
01:13:54.660 heavily influenced by his religious creed,
01:13:58.760 where he is an adherent, for the sake of being
01:14:01.220 respectful, I don't want to cast stones here,
01:14:03.980 whose religious view is that meat is bad,
01:14:06.400 in part because it elicits carnal desires.
01:14:09.700 And so it's a literal function of this individual's
01:14:11.840 religion at the time.
01:14:13.060 Again, in opposition-
01:14:13.980 Didn't Kellogg believe that as well?
01:14:16.120 Oh, in fact, Kellogg was one of the adherents.
01:14:16.920 Because he was just as-
01:14:17.840 He was one of the adherents.
01:14:19.080 He was completely-
01:14:19.840 Yeah.
01:14:19.980 So this is, the Seventh-day Adventists
01:14:22.100 were the ones who helped write the Food Guide Pyramid
01:14:25.100 and then helped create some of these,
01:14:27.660 guess who is the main origin of the American Dietetics
01:14:31.460 Association, the Seventh-day Adventists.
01:14:34.220 And so no wonder it's part of this.
01:14:36.060 To literally get licensed as a dietician,
01:14:38.180 you have to play the game and say meat is bad.
01:14:40.600 Yeah.
01:14:40.920 Because it's, and as a religious man, again,
01:14:43.540 I can't help but just have a grim humor,
01:14:46.160 where in the New Testament, the Apostle Paul,
01:14:48.560 who I love because he was so, he was like a lion.
01:14:51.640 In some of his writings to the, to Timothy,
01:14:54.700 in 1 Timothy chapter four, anyone go read this,
01:14:57.160 he's prophesying of the latter days.
01:14:59.340 And so it's just an irony that it's religious ideology
01:15:01.560 that helped give birth to these ridiculous ideas.
01:15:04.000 When if you actually scrutinize the text,
01:15:06.480 it doesn't support it.
01:15:07.700 So Paul, prophesying of the latter days says,
01:15:10.880 in the latter days, people will be seduced.
01:15:12.640 Now he is quite bold and says,
01:15:14.480 seduced by the spirits of devils.
01:15:15.980 Now I'm not saying every person
01:15:17.700 who believes this is devilish,
01:15:19.200 but he says there will be two things
01:15:21.080 that will kind of identify them.
01:15:22.980 They will command to abstain from marriage,
01:15:24.960 which is directly opposed to God's commandment
01:15:27.120 to Adam and Eve.
01:15:28.220 And then two, command to abstain from eating meat.
01:15:31.860 Who, and then he goes on to say,
01:15:33.040 which God has ordained for the use of man.
01:15:35.160 And so it's ironic to me that religion is invoked
01:15:38.500 to create these terrible ideas.
01:15:40.340 And yet a sort of studious view of religious text
01:15:44.520 would never support such a thing
01:15:46.200 and indeed directly oppose it.
01:15:48.580 Okay, so let's sum up.
01:15:50.300 And before we move to the Daily Wire side.
01:15:52.520 So there's a fervor in America at the moment
01:15:59.080 with regards to health.
01:16:00.480 And I think really that's probably a consequence
01:16:03.820 of the fact that everyone's fat.
01:16:06.300 And it's like, what the hell?
01:16:07.720 Like, how did this happen?
01:16:08.840 And we spend so much on healthcare.
01:16:11.900 Right, and that as well.
01:16:13.340 These ballooning healthcare costs
01:16:15.380 that aren't helping the problem.
01:16:16.840 Not helping.
01:16:17.220 Right, and a growing distrust
01:16:21.000 of the pharmaceutical Band-Aid treatment
01:16:25.000 to the problem.
01:16:26.100 And of government policy in general,
01:16:29.100 especially policy related to such travesties
01:16:32.340 as the food guide.
01:16:33.360 Okay, so everybody's kind of woken up and gone,
01:16:35.660 well, this isn't working.
01:16:37.040 All right, so what's the fundamental problem?
01:16:39.640 Well, we've walked through it.
01:16:40.820 The fundamental problem is that carbohydrates
01:16:43.620 are too cheap, plentiful, and promoted.
01:16:48.040 And that's making everyone insulin resistant
01:16:51.400 and fat and promoting Alzheimer's
01:16:55.380 and cancer and heart disease
01:16:56.680 and erectile dysfunction
01:16:57.660 and other reproductive malfunctions
01:17:00.080 and cognitive decline.
01:17:01.800 We didn't even talk about depression and anxiety.
01:17:04.520 Depression is often,
01:17:06.540 and this has been known for three decades,
01:17:08.540 that there are variants of depression
01:17:10.680 that are immunologically related.
01:17:12.580 They're inflammatory.
01:17:13.520 It's an inflammatory condition.
01:17:14.840 Yeah.
01:17:15.360 Right, right.
01:17:16.040 And so that's a huge problem
01:17:17.680 because depression per se
01:17:19.440 is probably 75% of mental health problem,
01:17:23.580 all things considered, right?
01:17:24.820 Yeah.
01:17:24.940 With case studies finding ketogenic diets
01:17:27.380 are once again therapeutic.
01:17:28.820 Yeah, yeah.
01:17:29.220 Chris Potter.
01:17:29.960 You can look across,
01:17:30.760 yes, exactly.
01:17:31.440 You can look across a span of neurological disorders
01:17:34.200 that seemingly are unrelated.
01:17:36.200 Alzheimer's disease, epilepsy, migraines, depression,
01:17:40.040 and yet all of them have been documented
01:17:42.040 to have what's called a brain glucose hypometabolism,
01:17:46.480 where in each of those instances,
01:17:47.720 if you're actually measuring the degree
01:17:49.140 to which these people are able to take in
01:17:50.920 and metabolize glucose in the brain,
01:17:52.800 it's significantly lower than their counterpart
01:17:55.260 who isn't suffering from that neurological disorder.
01:17:58.680 All the more reason to give the brain a fuel
01:18:01.540 that it can get, namely ketones.
01:18:03.620 Right, right.
01:18:04.280 So one of the suggestions
01:18:06.300 that might emerge from a discussion like this
01:18:08.520 is that if you are unhealthy,
01:18:11.220 why wouldn't the first thing you try
01:18:13.980 be a ketogenic diet?
01:18:16.380 Control carbs.
01:18:17.440 Yeah, yeah.
01:18:17.920 Always that is my rule number one.
01:18:19.300 Yeah, yeah.
01:18:19.680 Start with that.
01:18:20.560 Yes.
01:18:20.920 Kind of no matter what's wrong with you.
01:18:23.020 Yes, control carbs.
01:18:24.400 If it's chronic and you're having a hard time treating it
01:18:27.140 and the direction isn't good,
01:18:29.520 you should give some serious consideration
01:18:34.200 to radically decreasing your carb intake.
01:18:36.200 Yeah, and there's no downside.
01:18:37.060 Maybe just zero.
01:18:37.620 Yes, there's no, I mean, people have to appreciate,
01:18:39.880 well, what's the downside?
01:18:40.860 There is none.
01:18:41.680 Right, because there's no recommended daily allowance.
01:18:44.040 Exactly.
01:18:44.620 This is the one,
01:18:45.300 there are such things as essential fats.
01:18:47.300 You better get them.
01:18:48.200 There are such things as essential proteins or amino acids.
01:18:50.640 You better get them.
01:18:52.460 Crickets chirping.
01:18:53.680 There's no such thing as an essential carbohydrate.
01:18:55.960 So lest it seem like you and I are being just crazy,
01:18:58.580 no, rule number one, control carbs.
01:19:00.880 They are the one that is the main contributor
01:19:03.080 to your disease in the first place,
01:19:04.660 and two, you literally do not need them.
01:19:06.980 Right, right.
01:19:07.520 So let that one be the first.
01:19:08.040 So the negative consequences are zero.
01:19:11.660 Zero.
01:19:12.380 Right, right.
01:19:13.120 So you have a broadly applicable medical intervention
01:19:16.840 that's dietary-based.
01:19:18.700 Yep.
01:19:19.500 That's very likely to be successful
01:19:21.380 in treating a whole variety of diseases,
01:19:23.520 including ones that will kill you
01:19:24.960 in ways you do not want to die,
01:19:27.300 which would be Alzheimer's and diabetes, let's say,
01:19:29.720 or any degenerative neurological condition.
01:19:32.620 And the side effect profile is nil,
01:19:36.040 except that you get thinner and better looking,
01:19:38.340 and your sex life improves.
01:19:39.740 Yes.
01:19:40.320 Okay, that's a good place to end.
01:19:41.680 Yeah, I'm sold.
01:19:42.020 Yeah, I've convinced myself again.
01:19:43.800 Yeah, yeah.
01:19:44.180 Okay, so I think what we should do
01:19:45.740 on the Daily Wire side
01:19:46.660 is talk a little bit more about
01:19:48.060 how this came about, right,
01:19:50.100 and delve into that for everybody's edification,
01:19:52.840 hypothetically including our own.
01:19:55.380 For all of you watching and listening,
01:19:58.100 you can hear my guests' lectures on Peterson Academy.
01:20:02.160 Tell me the lectures that you've done so far for us.
01:20:05.220 You've done three, I believe.
01:20:06.320 I've done three, yeah.
01:20:07.380 And this is so orchestrated by Michaela,
01:20:09.440 who's just been such a champion for this message.
01:20:11.660 So the first one at Michaela's explicit invitation
01:20:14.560 was why we get sick,
01:20:15.780 which was essentially a longer version
01:20:18.840 of everything we've been talking about.
01:20:20.980 Six or seven hours of what is insulin resistance?
01:20:23.720 Why does it matter?
01:20:24.620 Where does it come from?
01:20:25.420 And what to do about it?
01:20:27.060 And then after that,
01:20:28.760 I was invited back to just say,
01:20:30.820 they sort of thought,
01:20:31.740 we need a little more kind of basic science and biology.
01:20:34.620 So I have two other courses
01:20:35.800 and I have an affection for alliteration,
01:20:38.720 basics in biology and fundamentals of physiology.
01:20:42.160 So those are the three.
01:20:43.120 Why do we get sick?
01:20:43.980 Basics in biology and fundamentals in physiology.
01:20:45.920 Right, so you can dig more.
01:20:46.960 People who are watching those can start at the surface
01:20:49.460 and get the bulk of the information like we did today.
01:20:52.520 That's right.
01:20:52.740 But then they can dig down for deeper understanding.
01:20:55.520 As a professor,
01:20:56.520 it really is sort of a seven hour version
01:20:58.840 of what I would take a semester to do.
01:21:00.700 Yeah, yeah.
01:21:01.320 Which I appreciate the point of this
01:21:03.280 as much as you and I both rail
01:21:04.700 against traditional higher education.
01:21:06.840 Anyone who's curious and thinking,
01:21:08.460 you know what?
01:21:08.800 I kind of liked my high school biology
01:21:10.540 and I wouldn't mind a little more.
01:21:12.280 Well, I got the class for you.
01:21:13.600 Yeah.
01:21:13.900 Or they want to go a little further
01:21:15.040 and understand how the systems of the body,
01:21:16.800 how's the heart working?
01:21:17.720 How's the brain functioning?
01:21:19.120 How are the lungs being dynamic?
01:21:20.480 The muscles, well, that's physiology.
01:21:22.800 And then the last part of it is
01:21:24.100 when things start to go wrong, if you will,
01:21:26.520 but a version of everything we've been talking about,
01:21:29.160 which is basically the metabolic origins of chronic disease.
01:21:31.540 That's why we get sick.
01:21:32.320 Right, right, right, right.
01:21:33.740 Okay, okay.
01:21:34.620 Well, I think that's what we'll focus on
01:21:36.900 on the Daily Wire side.
01:21:38.100 But I want to tilt the conversation again
01:21:41.100 or focus the conversation more
01:21:42.680 with regards to pathological policy in the past
01:21:46.420 and why that emerged.
01:21:47.660 Because it really is a story that'll just,
01:21:50.300 it just curdles your heart
01:21:52.280 to understand what was done
01:21:53.800 to the American population with the food pyramid.
01:21:55.980 It's beyond comprehension.
01:21:57.320 But more importantly, perhaps,
01:21:59.980 to understand and to investigate
01:22:03.160 how that might be put right.
01:22:05.060 Because the Maha people are trying to figure out
01:22:08.020 how to communicate directly
01:22:09.620 with the American population
01:22:10.860 to reverse this as rapidly as possible
01:22:13.900 and as sustainably as possible
01:22:15.760 without a heavy-handed sort of top-down approach.
01:22:18.320 So we could discuss that practically
01:22:19.920 on the Daily Wire side.
01:22:20.960 So all of you who are watching and listening,
01:22:23.220 join us for that.
01:22:23.900 We'll see you next time.
01:22:24.900 We'll see you next time.
01:22:25.900 Bye.
01:22:26.900 Bye.
01:22:27.900 Bye.
01:22:28.900 Bye.
01:22:29.900 Bye.
01:22:30.900 Bye.
01:22:31.900 Bye.
01:22:32.900 Bye.