Dr. Richard Heyer studies the neurobasis of human intelligence and cognition, and works with neuroimaging technologies to study individual differences in mental ability. He received his PhD in psychology from the Johns Hopkins University in 1975 and has since held appointments in the intramural research program at the National Institute of Mental Health and the Medical School at Brown University and the University of California at Irvine, he has served on the editorial board of three journals, Neuroimage, Intelligence, and Psychiatry Research, he also served as guest editor for a special issue on brain imaging research for the journal Intelligence, he provides neuroscience consultation to university research groups, corporations, foundations, and educational and legal professionals, and has appeared in numerous media outlets. In 2012, his research was featured on NOVA Science Now and he received the Distinguished Contributor Award for the International Society for Intelligence Research. In 2013, the teaching company invited Dr. Heyer to create an 18-lecture course called The Intelligent Brain. In this episode, we discuss how he got interested in intelligence research and how he became interested in the topic, and why it's important to understand how intelligence is shaped by the brain. the most controversial topic in social science, strangely enough. You can support these podcasts by donating to Dr. Jordan B. Peterson's PODCAST by Donating to his Poddy Project, the link to which can be found in the description of the podcast can be located here. Let this be the first step towards the brighter future you deserve. Dr. Peterson is a great resource for those struggling with Depression, Anxiety, Depression, and Depression. and other conditions that affect us all of us, and we can be helped by Dr. Dr. B.B. Peterson s new series, Daily Wire Plus now and start watching Dr. Poddy's new series on Dailywire Plus now. . Go to DailyWire Plus now, and start helping to support the podcast by Donate to the podcast today! Subscribe to Dailywireplus.org/TheIntelligentBrain.org and become a supporter by becoming a supporter of DailyWirePlus. Let's all of you can be apart of the team! . . . and let's all be a part of the community that builds a better, kinder, more connected, more aware, and kinder community. Thank you for listening, caring, and more connected than ever before we know we're all in this day and day to day life.
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00:01:12.020Dr. Richard Heyer studies the neurobasis of human intelligence and cognition.
00:01:37.080He works with neuroimaging technologies to study individual differences in mental ability.
00:01:42.260He received his PhD in psychology from the Johns Hopkins University in 1975
00:01:46.680and has since held appointments in the intramural research program at the National Institute of Mental Health
00:01:52.620and the Medical School at Brown University and the University of California at Irvine.
00:01:58.340Irvine, he has served on the editorial board of three journals, Neuro Image, Intelligence, and Psychiatry Research.
00:02:05.420He also served as guest editor for a special issue on brain imaging research for the journal Intelligence.
00:02:10.660He provides neuroscience consultation to university research groups, corporations, foundations, and educational and legal professionals.
00:02:18.660He's a popular lecturer and has appeared in numerous media outlets.
00:02:22.180In 2012, his research was featured on NOVA Science Now and he received the Distinguished Contributor Award for the International Society for Intelligence Research.
00:02:32.180In 2013, the teaching company invited Richard to create an 18-lecture course called The Intelligent Brain.
00:02:40.520So welcome to Dr. Richard Heyer today and we're going to talk about the most controversy of all topics, I would say, in social science, strangely enough.
00:02:51.260So maybe we could start with a little bit of historical information.
00:02:56.920I would like to know how you got interested in IQ research or intelligence research, let's say.
00:03:03.100And so let's start with that and then we can start diving into the nitty-gritty.
00:03:07.840Well, really, it started in graduate school at Hopkins when I really became most interested in personality research.
00:03:18.940And I started out studying individual differences in personality, but just by happenstance, the year I started graduate school in 1971 was the year one of the professors there, Julian Stanley, was starting a study of mathematically precocious youth.
00:03:38.460And I was one of the proctors at the very first talent search for mathematically precocious kids.
00:03:46.760And I wrote my first couple of books as book chapters in books that Stanley was editing about this project.
00:03:55.100And I saw these kids, age 10, 11, 12, who were scoring higher on SAT math than Hopkins freshmen.
00:04:07.220And the question was, you know, how does this happen?
00:04:10.620So that was kind of my earliest interest.
00:04:13.540And in graduate school, although I really completed my dissertation on personality,
00:04:20.860I took my first job at the National Institute of Mental Health in the intramural research program in the Laboratory of Psychology and Psychopathology,
00:04:33.520which at the time, the lab director was David Rosenthal, who had just finished the Denmark Adoption Studies of Schizophrenia.
00:05:25.100And so that's the origin of my interest in the brain and in technologies to make brain measurements and relate that to individual differences.
00:06:00.300Well, part of the reason I was so excited to talk to you is that I've done a very large amount of research,
00:06:07.080especially not so much practical lab research, but investigation into the structure of intelligence and into its measurement.
00:06:13.080We designed back in 1993 with a student of mine, Daniel Higgins.
00:06:17.120We designed, I think, what was probably the first online battery purporting to measure the cognitive abilities associated with dorsolateral prefrontal cortex, right?
00:06:27.120So hypothetically the highest order cognitive functions in the brain.
00:06:30.560And we found much to our chagrin, I would say, and this was a very painful discovery,
00:06:35.400that a lot of what we had been thinking about as potentially separable neuropsychological functions were pretty easily collapsible into good old general intelligence,
00:06:48.340you know, that killer central factor that seems to unite cognitive abilities.
00:06:51.860And so it was quite a shock, especially because the neuropsychologists of the time, and they still do this,
00:06:58.080aren't as assiduous investigators of the psychometric intelligence literature as they should be,
00:07:06.620and tend to underestimate the central power of that initial factor.
00:07:10.640So anyways, I'm really interested in intelligence research, partly from a practical perspective, too,
00:07:15.740because the industrial organizational psychology literature is crystal clear.
00:07:19.800For complex jobs, the best predictor of long-term success is intelligence.
00:07:24.220And it's a predictor that's probably, say, imagine you give it an R of 0.4 to 0.5, which is pretty decent.
00:19:23.740Well, that was something that Murray and Herrnstein wrote about in their book, The Bell Curve, which really struck me,
00:19:28.540because I read that book twice, unlike most of the people who criticized it.
00:19:31.760And, you know, one of the things that they pointed out in there was, look, the typical educated person thinks that someone isn't very bright if they have an IQ of 115.
00:19:44.860So we're talking about graduate level and PhD level research institutions, right?
00:19:50.800Because 115, there's as many people at 115 above as there are at 85 and below.
00:19:57.460And so it's a minority of the population.
00:21:05.420It is a, I mean, just, just barely begins to describe it.
00:21:11.680I had a, I had a client who, he probably had an IQ of under 80, the nonverbal portion of it anyways.
00:21:18.120And he was indistinguishable in physical appearance from, from, let's say, I hate to use the frame normal person,
00:21:25.720but there's nothing marked, that marked him out about particularly intellectually impaired, you know.
00:21:30.440And, uh, I tried at one point, this is, this, this was so, so telling to me.
00:21:37.320I got him a, uh, a volunteer job, which, by the way, is very difficult.
00:21:41.720It's harder to get a volunteer job than a real job, because you have to do police screening and all sorts of things.
00:21:46.200And the selection process is just as extreme.
00:21:48.160But I eventually ended up getting him a job at a bike store, bike slash bookstore.
00:21:53.760And, but that place couldn't hold him once the subsidy program had expired.
00:21:58.340And then I got him a job at a charity, and his job was to fold letters into three so that they could be put into envelopes.
00:22:07.520Well, that sounds easy, except that he also had a bit of a motor tremor.
00:22:12.120And, you know, it took me about 30 hours to train him to fold up a piece of paper with sufficient precision,
00:22:19.700so that it could be put in an envelope rapidly, so that the envelope wasn't so mangled that it would get stuck in the automatic sorting machine.
00:22:27.180And, you know, there was high performance demands on him, too.
00:22:30.120He had to whip through those letters pretty quickly.
00:22:32.140And then sometimes the letters would have a photograph appended to them that was stapled on.
00:22:39.160And they weren't always stapled on in the same place.
00:22:41.700So then he had to calculate how to fold the paper over the photograph without bending the photograph in precise thirds so that it would still fit in the envelope.
00:22:50.320And then he had to separate the French letters from the English letters and associate them with the proper envelopes.
00:22:57.560And, like, that level of complexity just did him in.
00:23:04.140One is, I hope, common sense, and the other is pretty provocative.
00:23:08.200The common sense thing is we have to be very careful when we have these discussions not to devalue the human dignity of people who aren't in the upper end of the distribution.
00:23:21.500And if there's one criticism that I think is fair is sometimes in these conversations it sounds like we're devaluing people at, you know, the lower end of the distribution.
00:23:33.380And we have to be very careful that we don't do that.
00:23:36.460Human life has dignity, and IQ is not the most important thing that defines human beings.
00:24:10.160I'm trying to make the point about how difficult it is for people who are on the low end of the cognitive spectrum to survive in an increasingly complex, cognitively sophisticated environment.
00:24:54.300Well, the relationship between IQ and learning is even more powerful than the relationship between IQ and job performance.
00:25:00.240That's right, which is kind of common sense or it matches our common sense.
00:25:04.040But, you know, if you put a bunch of variables into a regression equation to predict academic achievement and you have all these school quality variables and teacher quality variables and cognitive variables of the students and what you find is the teacher variables and the quality of the school variables together barely account for 10% of the variance.
00:25:29.400Yeah, I know, I know, I know, I know, I know, it's terrible, it's terrible, well, you know, and I talked to the guy who ran admissions at Harvard, I taught at Harvard for a while, his name was Dean Whitlaw and he is a really smart guy, I really liked Dean and you know, he was, let's say he was on the right side of the human race and he was really trying to figure out how to run the admissions policy at Harvard so that it did the best for everyone concerned.
00:25:51.140And he had run an interesting series of analysis that I don't believe he ever published and one of them was, well, let's say you segregate the Harvard population into the relatively low IQ kids, so maybe they only have an IQ of 130, you know, and the relatively high IQ kids who are pushing up towards to 160.
00:26:09.540So you got two competing hypotheses there, one would be that the lower IQ kids come to Harvard, this remarkable environment and they thrive because of the high educational quality so well that they close the gap between them and the 160 kids and that's just completely wrong.
00:26:31.540What happens is you put both those groups there, both very, very highly selected but some, you know, in this sort of superman rage intellectually, what happens is the gap just gets bigger and bigger as they progress through university.
00:26:46.540And it's a dreaded example of that Matthew principle that the economists talk about which is, you know, to those who have, more will be given and from those who have nothing, everything will be taken.
00:26:58.540It's very, very, very, it's no wonder people dislike this research.
00:27:02.620It's so, it's so anti-egalitarian in its essential, in its essential structure.
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00:29:55.680Well, I wanted to make a second point that I said would be provocative.
00:29:59.400If you want to do something about this, you know, we tried a bunch of interventions, earnest, well-funded, long-term interventions don't seem to work, but neuroscience has been excluded from discussions about what to do about this.
00:30:17.820And I believe that neuroscience, the progress in neuroscience research has the potential to really dramatically increase the G-factor.
00:30:31.060Well, that's an optimistic statement, so I'm sure we're looking forward to some support for that one.
00:30:38.520And, you know, just as a thought experiment, and I can tell you why I believe this is possible.
00:30:46.140Well, first, before I tell you the thought experiment, the reason I'm optimistic is that it is because of the high heritability of the G-factor.
00:30:56.680That means, you know, if genes are involved, genes work through biology, even if environment interacts with that.
00:31:03.160But, basically, you have a neurobiological system.
00:31:07.240It's complex, but as you begin to understand it, you can tweak it.
00:31:12.300This is what all medicine is doing now.
00:31:14.680They're trying to understand the neurobiology slash genetic basis of our health and our diseases.
00:33:51.440And so what we found is that there are some personality effects.
00:33:54.920So extroverted, enthusiastic women tend to rate men, generally speaking, as more attractive than introverted and less enthusiastic women.
00:34:03.440And so there are some just straight personality effects, but the biggest effect by far we found was the proclivity of women in general to rate men as less attractive as the women's IQ increased.
00:34:17.060And so the other thing that we don't know is what price we pay for, for accelerated IQ from a, from a broader perspective, you know,
00:34:26.140because I know that there is some evidence and you can tell me what you think about this, because I know that there's reasonable evidence that the average IQ of the Ashkenazi Jewish population is about 15 points higher than the standard population,
00:34:39.940which kind of makes it a thought experiment that's, or an experiment, real life experiment that's equivalent to the one that you laid out.
00:34:46.240But Ashkenazi Jews also tend to suffer from a host of neurological diseases that seem to be associated with increased neuroplasticity.
00:34:53.680And so to me, it's often, it's often hard to gain on one front without losing on another.
00:34:59.440You know, I mean, that's the evolutionary conundrum, obviously, but.
00:35:03.020We call that the social justice theory.
00:35:06.100It's not one thing you have to be bad on everything else to kind of balance it out.
00:35:10.340Yeah, well, generally speaking, you do pay a price for your, for your exceptionalism, you know.
00:35:14.960I don't think that's true because, you know, the, the Julian Stanley studies of the mathematically precocious kids essentially found not only were they smart,
00:35:24.760but they were more mature than their age peers.
00:35:34.780Well, I mean, it's just, that also might be true because one of the things that, that, that can interfere with IQ is poor health and, and poor nutritional quality and all of that.
00:35:45.420I mean, it doesn't look like it's that easy to increase IQ, but it looks like it's pretty easy to decrease it.
00:35:50.140Yeah, you know, I think that those, those things have to be pretty extreme to have an effect and those effects may not be permanent actually.
00:36:01.900There's some studies of deprivation of people who suffered, suffered deprivation during the Second World War that suggest that those, really severe deprivations didn't have lasting effects on them.
00:36:16.620Well, you know, well, people are pretty tough, so I'm inclined to agree with that.
00:36:21.160So, so have you seen any animal experiment, experimental work that you regard as compelling that shows something like the transformation of, of animal cognition into a, into something that's, that's, that's, that's higher order that, that you regard as compelling?
00:36:35.460I'm not sure what you mean, but there's certainly animal work, uh, that shows you can extract a G factor from cognitive tests given to various animals.
00:36:45.460Right, so, so what I was wondering is, has there been any evidence that you regard as credible showing that that could be, that that, say, so-called animal G factor extracted in the same, we should tell our readers too, the way you extract the G factor, I'm, I'm going to say it very, very rapidly, is,
00:37:01.340imagine you take a, um, a randomly set, a randomly selected set of 200 questions that require abstraction of one form or another to solve,
00:37:13.680and then you give those 200 questions to 100 people, and you sum the scores, and you rank order them, you get something that's roughly equivalent there to a G factor, it's roughly that.
00:37:26.280So, just, I would say it a little bit differently, just, okay, so everyone's on the same page, if you think of all the different mental abilities, and you devise a test for each one of them,
00:37:39.200and you gave this test to a, a lot of people across the, the range of ability, what you'll find is the scores on all those tests are positively correlated with each other,
00:37:50.620suggesting that all tests of mental ability have something in common.
00:37:55.080Right, right, sure, that's a great way of putting it.
00:37:56.660Common is this G factor, this general ability to reason, and some individual tests have more G loading than other individual tests.
00:38:13.820If I said to you, repeat the following numbers back to me, three, seven, two, one, six, five, that's not a very highly G loaded mental ability to be able to do that.
00:38:28.600But if I gave you a string like that, and said, repeat them to me backwards, that becomes a G loaded ability, because you do a transformation.
00:38:38.360Yes, well, the other thing to say about that, too, is that the positive relationship between those multiple assessments that you described is actually quite high.
00:38:47.980Right, that's the thing, is that that general factor not only exists across domains of cognitive ability, but it tends to account for a substantial amount of the ability in each of those domains.
00:39:00.240So it's kind of like a, G is kind of like a black hole for intelligence research, and everything keeps falling into it.
00:39:05.980So that's an interesting way to put it, because now we have these genome-wide association studies that are finding these bits of DNA that are related to a latent factor of intelligence, which is the G factor, or to what they call educational attainment variables.
00:39:28.360Educational attainment is so highly correlated with IQ that it's essentially the same thing.
00:39:34.100So we're really moving, when I was in graduate school, the question was, is there a genetic component to intelligence or not, to this kind of DNA analysis, trying to find bits of DNA that are going to be related to what we call intelligence, or IQ testing, or the G factor.
00:39:58.260And they seem to exist, and they seem to exist, there seems to be hundreds of them, in each a tiny effect, which will make the ultimate story extremely complicated.
00:40:10.540But as I said before, I think it's a finite set of problems.
00:41:46.520Well, we should also be clear about this because it is so politically suspect is that it's not like it's self-evident that people who have less cognitive capability are likely to end up poor because there are serious, complex problems in life that beset them that they have a difficult time dealing with, and they can't learn as quickly.
00:42:14.260And so the relationship between poverty and intelligence is self-evident if you're willing to think it through for any length of time.
00:42:22.620It doesn't mean that everybody who's rich that is – it doesn't mean that everyone who is rich is smart, and it doesn't mean that everyone who is poor is stupid, to be blunt.
00:42:34.160But what it does mean is that if you're intelligent, you're much more likely to become financially successful.
00:42:38.640And I think it was the Herrnstein – Herrnstein and Murray, I think, did the calculations back in the bell curve that indicated that if you imagine that you could – you were a fairy godmother, and you have your newborn grandchild in front of you, and you can grant them three standard deviations above the mean in terms of wealth at birth,
00:43:00.600or you can grant them three standard deviations above the mean in terms of IQ at birth, and then you wanted to determine which would work better for them by the time they were 40.
00:43:10.660And the answer to that was quite clear, is that IQ trumps wealth in terms of ability to predict a positive future.
00:43:19.020Yeah, and that's why I'm so interested in the concept of increasing IQ or increasing the G factor, not just the IQ score, but really what under this reasoning ability.
00:43:33.100So, you know, some people have tried to teach college students critical thinking.
00:43:45.300And, you know, it may sound to your listeners – I just want to take a moment out here.
00:43:48.900It may sound to your listeners like, here are these two guys pontificating about what it's like to be smart, what it's like to be not so smart.
00:43:56.160I mean, the point of this, the point of neuroscience research on intelligence, and what I hope to achieve by writing the book,
00:44:04.480was to show that the genetic aspects are not deterministic.
00:44:13.940So, the extent to which something like intelligence is genetic, in my view, is the extent to which we'll learn how to change it for the better.
00:44:23.600Well, that's definitely – yeah, because people do tend to think about biological factors as deterministic, and that's a mistake because they can be shifted.
00:44:31.160So, with regards to the animal study, so, you know, you pointed out that you can come up with an IQ-like estimate for, say, a rat.
00:44:38.720And have you seen anything that indicates – I don't care how it's done, through training or neurochemically or by promoting brain function in different ways, however you might do it –
00:44:52.080that's actually indicated to you that there is a way of biologically enhancing the general cognitive ability, even of an animal?
00:45:17.680There are some interesting technologies that have been developed where you can turn parts of a rat brain on and off at will and see what happens.
00:45:33.100This has not yet been applied, as far as I know, to learning.
00:45:37.080But, interestingly, there are human studies underway with things like transcranial magnetic stimulation and electrical ways to – low-voltage ways to stimulate parts of the brain.
00:45:56.660And there are some interesting experiments now being done with humans to see if you can improve learning or reasoning ability.
00:46:04.780As a matter of fact, you know, I edit this journal called Intelligence, which is kind of a prime spot for intelligence researchers to publish on all aspects of intelligence.
00:46:16.180And we're just starting to put together a special issue on human experiments to increase reasoning ability using these techniques of stimulating the brain.
00:46:27.160Are any of you – you've seen some positive things with regards to low-level electrical stimulation?
00:46:32.180Because that's also being used – you know, it's more anecdotal, but there's a bit of research being used to treat depression, for example.
00:46:40.060And I do cover in the book the studies that were published up until the time I wrote the book and cautioned people that they hadn't been replicated yet.
00:46:53.460I mean, this is an evolving area that's going to be very exciting.
00:46:57.780I mean, if students are listening to this podcast and they're thinking about neuroscience or psychology,
00:47:04.280this kind of experiment is really a new phase of intelligence research where you can do experiments on human beings that are completely ethical and relatively non-intrusive.
00:47:19.280And this is really going to change everything now because it will shift intelligence research from basically psychometric correlations past what neuroimaging has done,
00:47:35.680which really moved it away from just psychometrics.
00:47:39.180And then, you know, correlating psychometric scores with measurable aspects of the brain like glucose metabolic function or the amount of gray matter or white matter or the number of white matter fibers.
00:47:52.840I mean, there are all these fabulous connections.
00:47:59.160But that phase is now moving into this new phase of actually stimulating the brain to improve learning and memory and reasoning and all the while doing it with neuroimaging to see what happens and adding DNA to it.
00:48:27.320Well, there's some optimism on the horizon.
00:48:29.240I mean, I looked for a while because I've been very interested in improving human performance, measuring it and improving it.
00:48:37.640And so I looked and doing that also in conjunction with businesses because I'd like things to have a practical end.
00:48:44.340And, you know, I looked to find out what the research indicated with regards to improvement of intelligence.
00:48:49.940And mostly what I found was not so much improvement as conservation is that if you exercise both aerobically and with weightlifting, that that can help you maintain your fluid intelligence across for longer across your lifespan.
00:49:06.020Because it tends to decline rather precipitously as you age, which is one of the more dismal things that you also discover with IQ research.
00:49:13.340And it starts to decline when you're in your early 20s.
00:49:15.800And it's kind of linear downhill all the way along.
00:49:20.420But it's preservation, which is pretty important at my age.
00:49:26.460Yeah, preservation is a big deal, man, but enhancement would be good.
00:49:30.800But, you know, this thing about an IQ pill coming up with a way, you know, to manipulate the neurobiology of your brain regarding intellect, if there's a breakthrough in this, it will come either from Alzheimer's research or from normal aging research.
00:49:52.060Trying to prevent the slow decline of your mental faculties as you age, especially fluid intelligence, or trying to reverse the ravages of Alzheimer's disease.
00:50:09.600Yes, well, an IQ seems to be quite tightly linked to.
00:50:13.020Well, this is another thing we could talk about.
00:50:14.480So, I know that there are certain biological markers that IQ is loosely associated with.
00:50:23.720So, you know, it predicts in a fragmentary matter.
00:50:28.040So, I know that even something as simple as simple reaction time, how fast you can push a button when a light comes on, is correlated with IQ, with fluid intelligence at about 0.2.
00:50:38.200And having a bigger head is slightly correlated, especially when you correct for body size.
00:50:44.940And so is thickness of the myelin sheaths on individual neurons.
00:50:49.840And so, there's these micro markers of, you might think about them as neurological integrity that seem to predict IQ.
00:50:57.140But you've been doing neuroimaging, and I'm not as up on that.
00:51:00.000I haven't looked at that for a couple of years.
00:51:01.560So, what have the neuroimagers found about brain structure and function in relationship to intelligence that you think is compelling and interesting?
00:51:10.800I'm glad you asked this, because as I was finishing the manuscript for the book, literally, the day after I turned it in, I had to ask for it back.
00:51:23.240Because there was this very interesting study published by a group at Yale that used a fairly sophisticated way to look at white matter connections.
00:51:35.920It's functional, structural, structural, white matter connections, and functional connections in the brain.
00:51:44.480And determining how one brain area is functionally or structurally related to all other brain areas.
00:51:54.680And you can put up a map of a person's brain that shows from brain imaging, from MRI technology, how their brain is interconnected.
00:52:09.720And this paper said these interconnections are so reliable within a person that they're like fingerprints.
00:52:18.080And not only that, but the fingerprints can predict IQ.
00:52:25.760And so, was it density of connections, density of interconnections, or something like that?
00:52:30.120Or was there something more specific going on?
00:52:32.900It can be the density of connections structurally, how much white matter connects this area to that area.
00:52:40.560You know, and there are certain brain areas where you have a lot of white matter coming in, and a lot of white matter going out to other parts of the brain.
00:52:50.520And there are nodes that have lesser connections.
00:52:55.100And so, it makes kind of, it certainly makes sense that being able to make measurements of brain connectivity would be related to things like intelligence.
00:53:05.380Do you know, or do you remember what some of the major hubs were?
00:53:09.040Like, are they identifiable as, also as neuroanatomical areas with specific functions?
00:53:24.640But they, what was exciting to me is they mapped on to a model of brain intelligence relationships that I had developed with my colleague, Rex Jung, and published in 2007.
00:53:41.120And it's called the Parietal Frontal Integration Theory, or PFIT, of intelligence.
00:53:48.360And the idea is that the connections between the parietal lobe, which is here, and the frontal area, are the key connections for intelligence.
00:54:00.460Okay, so tell us, tell us why you derived that particular theory.
00:54:04.320Because, you know, people have suggested, say, alternatively, that the seat of higher order intelligence is basically, let's say, the dorsal lateral prefront cortex, or something like that.
00:54:14.480So, why specifically the connection patterns between frontal and parietal areas?
00:54:21.060Well, this article in 2007 was a review article where we took every single brain imaging study we could find that included a measure of intelligence.
00:54:32.280And there were 37 such studies at the time, including some I had done as early as 1988, and others had done with much larger samples.
00:54:40.820And we just kind of qualitatively analyzed the results to see what brain areas came up in common across these studies using different measures, different imaging techniques.
00:54:54.780And we found that not all brain areas were equally distributed.
00:55:01.160They tended to be concentrated in the front and the parietal lobe.
00:55:05.500But also, we found areas in the occipital lobe and the temporal lobe that were also related to intelligence.
00:55:12.640And so, we developed this model that we talked about how information would be processed and how information would flow around this set of, I think there were 18 areas all week.
00:55:24.860And we hypothesized that people who scored high on intelligence tests would have some combination of these areas.
00:55:35.240You didn't need all of them kind of working together.
00:55:37.960But some people would have this combination.
00:55:40.460Some people would have that combination.
00:55:42.080And if you could make measurements about the way information was flowing around these areas with a technology like the magnetoencephalogram, which shows changes in the brain millisecond by millisecond, then you might be able to actually estimate IQ from brain images.
00:56:03.220So, in 2007, people were trying to do this with multiple regression equations.
00:56:19.000But these newer techniques, these mathematical techniques of calculating brain connectivity, really seemed to have advanced this whole thing dramatically.
00:56:29.240So, was there a map between the nodes that were identified in this more recent research and the areas that you guys had identified with your overarching analysis?
00:56:38.920To the way Rex Jung and I looked at the data, it seemed like there was considerable overlap.
00:56:46.400And some of the authors who we did not know personally, when they wrote their papers, noted that their findings were consistent with our model.
00:57:01.080There were more on the left than on the right, but there were also areas on the right as well.
00:57:07.880And these areas tend to be areas that are also related to language and memory and attention.
00:57:18.280So, the more fundamental cognitive processes of language and memory and attention seem to be the architecture on which intelligence is built.
00:57:31.800Hey, do you, here's a question that I haven't been able to figure out because I've looked at the attention literature a lot.
00:57:37.340And the more I look at the attention literature, the more I find it difficult to distinguish it from the intelligence literature.
00:57:43.580I mean, attention and intelligence seem to be different things.
00:57:47.240And we certainly use the words in common parlance as different.
00:57:50.160But I haven't really been able to, like, imagine you wanted to establish a battery of attention-related tests that were independent of G-loaded cognitive abilities.
00:58:03.780And so, do you, do you, what do you think the difference is between the capacity to pay attention, which also seems to be associated with conscientiousness, by the way, which isn't associated with IQ.
00:58:15.080But, I mean, what's the relationship between attention and intelligence as far as you're concerned?
00:58:21.280Those studies have been done where they take cognitive variables, the elemental cognitive tasks is what they call them.
00:58:29.020The real basic things that cognitive psychologists like to study because they like to study reasoning.
00:58:35.340You know, and they'll study learning and memory, but they don't want to address why some people learn faster than other people or why some people can remember more than other people.
00:58:46.280That's what cognitive psychologists study.
00:58:48.480They study what's common to everybody.
00:58:50.540But if you look at these elemental cognitive tasks, you can extract a G-factor of cognition, which is highly correlated with a psychometric G-factor.
00:59:16.880So, you know, I kind of have this idea from being a parent, watching my kids grow up, that people differ in their baseline of attention when they're not specifically paying attention.
01:00:01.240But, you know, there are these differences.
01:00:03.460And, you know, we've actually studied consciousness with brain imaging with my friend Mike Alkire, who's an anesthesiologist.
01:00:12.380We did the first imaging studies where we brought normal volunteers in and Mike gave them anesthetic drugs to knock them out completely while they underwent brain imaging.
01:00:27.140And we had different levels of anesthesia.
01:00:30.260We were trying to see what part of the brain is the last part of the brain to turn off when you lose consciousness.
01:00:35.800And did you find anything that you could make sense out of from that?
01:00:39.780Because, of course, that's obviously an extraordinarily interesting question.
01:00:43.560I mean, is it the collapse of these networks?
01:00:46.300Well, Mike Alkire is the real expert on this.
01:00:48.700He's published a whole series of papers.
01:00:50.520And the mechanism of consciousness is still one of the great Nobel Prize winning.
01:01:56.460He suggests that one of the consequences of psychedelic drugs is to decrease the gating of the thalamic cortical circuitry.
01:02:07.360And that that's one of the mechanisms whereby that expanded, at least, sense of consciousness emerges as a consequence of experimentation with the psychedelic end of the pharmaceutical universe.
01:02:20.620Yeah, I have a section in the book where I talk about consciousness and these studies and try to relate the concept that if you can turn consciousness off, you should be able to turn it on.
01:02:37.100We know anesthesiologists do this at will.
01:02:43.520You know, they can't tell you why it works.
01:02:49.460But then can you use, if anesthetic drugs kind of dissociate the brain and creativity seems to be related to a dissociation of the frontal lobes,
01:03:04.520can low doses, can low doses, very, very low doses of anesthetic drugs, cause just enough disinhibition to increase your creativity?