Cynthia Thurlow is a nurse practitioner, an expert in intermittent fasting, and a nutrition expert as well. She walks us through what intermittent fasting is, how to do it, and what to do if you find yourself in your eating window.
00:02:00.620You know, I think on so many levels, I have always been really interested in, you know, health and wellness, you know, trained as a nurse practitioner working in cardiology.
00:02:09.860I was able to see what was not working for many, many people.
00:02:13.840And I think it was probably close to the time that I was in my early 40s, and I started to see changes in my own body that definitely impacted my ability to, you know, maintain body, you know, body composition and, you know, just be, you know, healthy in my own skin.
00:02:31.940And so on many levels, I think I really came to it out of curiosity initially, you know, I read Jason Fung's book and felt that, you know, if there are other, you know, Western medicine trained providers that are really advocating for a strategy that's been around since biblical times, that it's probably something that I can consider myself.
00:02:51.680And so initially, the four, I was really selfish, it was to, you know, kind of, feel like I had some control over some of the changes that were happening in my early 40s.
00:03:02.600And then I felt so good, I intrinsically felt more energetic, I had much more mental clarity.
00:03:09.620And then I started thinking that this might be a great strategy to use with patients, and then with my own clients.
00:03:16.080And so that's initially how I started, but really, it was happenstance.
00:03:19.940And, you know, prior to that, you know, I certainly, you know, living in a very, you know, diverse area of the country, I certainly had lots of patients who practiced fasting as part of their religious rituals.
00:03:34.580And so it was something that was not, you know, uncommon for us to discuss, but it was certainly not something I thought I would be doing on a daily basis moving forward.
00:03:43.100But I'm so delighted that I found the strategy, and obviously, I'm a huge proponent of it.
00:03:47.760Yes. That's a good point. You know, I, I live on the Upper West Side of Manhattan, and I live in a building that's most mostly Orthodox Jewish people, and they fast all the time.
00:03:56.940And in my religion, Catholicism, we never have to fast. At least, I don't think so. I don't know all the rules perfectly.
00:04:02.400But I've never been told that I need to fast as a Catholic. So I never even thought I could do it. I mean, like, why would you do that to yourself? But like you, as I got into my late 40s, I went to my doctor and I said, you know, it used to be that if I were two or three pounds up, I would just watch what I ate for a week or two, and it'd be gone.
00:04:21.680And I'm noticing that's no longer the case. And he said, Yeah, he said, How old are you now? And I think at the time, I was 46 or 47. And he goes, Yeah, you're actually gonna have to try now.
00:04:31.460And I'm like, Oh, okay. You know, and he's like, he goes, And then once you get into your 50s, you won't be able to eat at all. He was joking, right? But he's, he's talking about what naturally happens, especially to women, but to women and men.
00:04:43.020And as we get older, our metabolism slows, and it's much harder to keep off the pounds, even though you're not necessarily eating more.
00:04:50.520Yeah, it is a sad fact of nature that there are lots of physiologic things that change in our bodies. As we're getting older, I always think about the fact that we become more likely to become insulin resistant as we get closer to menopause.
00:05:06.220You know, certainly we start losing lean muscle mass, and that is a normal function of aging unless we work against it.
00:05:11.880And so on so many levels, you know, your doctor is right. And unfortunately, that the game changes, if you will, what I could do in my 20s and 30s, I definitely can't do in my 40s. And as I get creeping closer to 50, same, same situation. So it's nice to know that there are opportunities where we feel like we have some control over things that we otherwise have no control over.
00:05:34.520Well, and he was saying to me what you said, too, which is in your 50s and 60s, the average woman gains one and a half pounds a year, right? A year, which in one year, that may not be a big deal.
00:05:46.500But over the course of 20 years, that's a major change in your body weight and your appearance and the way you feel. So his point was, you got to stay on top of it. Don't you know, like that one and a half pounds in one year actually does matter because it adds up.
00:06:00.960And that's really when I started to take a look at this. I'm like, okay, I don't want to diet. I don't really want to diet. So what what can I do? And intermittent fasting, it wasn't as hard as I thought it was going to be.
00:06:14.040I really thought it was going to be torture. But I and I follow the 16 eight method, which we'll get to and I think that's totally doable for people who even for people who are like, I couldn't possibly fast. But there's all sorts of ways that you can go about it. All right. So let's just talk about before we get to how you do it, the benefits for men and women, like what what will it do other than watch your weight, right and control weight, you can use it for weight loss or just weight, weight maintenance. But there's a lot of other benefits.
00:06:40.580I agree. So body composition, I always say that that's what brings people to intermittent fasting is they want to lose weight, but they stay for all the other benefits. So we know that we get improved mental clarity, because we have lowered insulin levels. For many people, they're surprised at how much more productive their mornings are. So improve mental clarity, what do you mean lowered insulin levels? And before you said we can get insulin resistant as we get older. So can you just talk about insulin for a second?
00:07:06.240Yeah, yeah. So insulin is a hormone. It's not a bad hormone. But it's a hormone that we want to master. And we want to ensure that we're not secreting insulin all day long, which is kind of aligned with this methodology slash dogma that many of us were raised with that you want to eat many meals and snacks. And that's how you are able to keep your metabolic fire going. It couldn't be farther from the truth. And so what happens when we're eating frequently throughout the day, whether it's sugar sweetened beverages,
00:07:36.080whether it is snacks and mini meals, what we are doing is we are secreting insulin more frequently. And with secreting insulin more frequently, what we're essentially doing is we shut off fat burning. And so what happens with intermittent fasting is you're eating less frequently. So you are using less insulin. And when you keep insulin low, it allows your body to use fat as a form of energy.
00:07:59.920And that is a really important principle for people to understand in a metabolically unhealthy population like we have. I think the latest statistic was 88% of Americans are metabolically unhealthy, which means they're either insulin resistant or obese or overweight.
00:08:14.960You really want to kind of embrace strategies that will try to keep your insulin levels better balanced. And one of those is just decreasing meal frequency and not snacking. So each one of those Starbucks, you know, people think of, and I don't mean to call it on Starbucks, but you know, there's sugary coffee beverages that are more like desserts. If you're having a couple of those a day in between meals, you're really setting yourself up for not being able to support, you know, support your body the way that it's designed to thrive.
00:08:42.280I didn't realize that. I didn't realize that. So you're saying not only should we be doing the intermittent fasting where you go a certain number of hours without eating anything. But you're saying even when you're in your eating window, you should not be snacking in between meals.
00:08:56.500No, because really, if you get your meals properly put together, meaning, you know, a certain amount of animal protein or plant based protein, depending on who you are, with some healthy fats, you should be satiated from lunch to dinner, you shouldn't be getting hungry in between. And if you are, it just means that you need to increase your protein portion at your next meal.
00:09:19.060And so a lot of what I talk about is just helping people understand what macronutrients are, which is protein, fat and carbs, so that they can structure their meals properly. So they're not getting hungry in between meals. And I feel on many levels, we've done ourselves a disservice telling people snacks and mini meals are the way to go, because that just contributes to that degree of metabolic inflexibility, because your insulin levels aren't being managed properly.
00:09:44.000And you're not tapping into your fat reserves the way you could be that that could be fueling your walk around town. Instead, you're using that insulin that you got from your little snack. Okay, so keep going with the with the benefits, sharper mental acuity, which I can say I have experienced that on intermittent fasting, I thought it would be the opposite. I thought, you know how if you go too long, without eating, they say, Oh, your blood sugar drops, and then you get a little cloudy that that that's happened to me. But on intermittent fasting, I have the opposite. I it's almost like a fight or flight.
00:10:13.540Feeling with your brain where it gets extra tuned in. Yeah. And that's absolutely related to the ketones that are produced in our in cross the blood brain barrier, which we can dive into. But in terms of other benefits, we know that you get improved biophysical markers. So while you're fasted, you're going to be improving your blood sugar levels, you're going to be improving your blood pressure, you have the ability to ultimately improve lab values that are done through your private primary care providers office or specialist
00:10:43.300office. We know that it helps reduce our, our likelihood of developing things like neurodegenerative disorders could be Parkinson's type three diabetes, which is Alzheimer's and another, another thing that we are more at risk for as we make that midlife transition.
00:11:00.300We know on many levels that for many people, it helps keep their hormones better balanced. So for many women or men that are going through these middle age changes, it helps with balancing. I touched on insulin already, but it helps balancing sex hormones. It can be very, very beneficial in helping people sleep better. I find that a lot of people that are experiencing sleep disorders, when they start fasting, that can be improved upon because they're not eating so close to bedtime.
00:11:28.100Their insulin, their insulin and blood sugar are better balanced. So they're not waking up in the middle of the night. I mean, those are some of the key things that we like to focus on. And one of the kind of nerdy science terms that I think everyone that fast should really be familiar with is autophagy. And so this is this waste and recycling process that goes on when we are in a fasted state and our bodies, when we start eating, it kind of down regulates, kind of stops that autophagy process.
00:11:55.460So when you think about the fact, by the time we hit the age of 40, we have plenty of, you know, it's kind of like tires on a car over a period of time, the tires get worn out and we replace the tires. And so when we're not eating, our body is able to go in and scavenge up disease and disordered cells that we need to get rid of.
00:12:13.200It's an efficiency process. But if we're eating more frequently, our body isn't able to go in and do that cleanup. It's almost like it takes out the garbage, but we can't take out the garbage if we're eating too frequently.
00:12:24.320So autophagy is a really key principle that I think is really important for people to understand and sometimes can help reinforce why eating less often really is something of tremendous benefit for our health.
00:12:35.760Well, that's the thing is like you you think of fasting as something that would be painful and potentially bad for you, uncomfortable. And the more I looked at it, the more I read articles and other thoughts saying, look, this is how our ancestors used to live.
00:12:50.440You know, they didn't have pantries full of food and refrigerators full of food. They might go two days between meals. And that was OK. And if you try to reframe the thought of fasting in your mind is not this painful, punishing thing, but something that is totally natural that you can get through and that the feeling of hunger doesn't have to be a bad feeling.
00:13:12.880It's it's it's more manageable. And I'm trying to I want to be careful because I certainly don't want to encourage eating disorders. Right. That's something I don't want to sort of get into the messaging that anorexics give to themselves.
00:13:23.860But I do think as a healthy person of a healthy body weight, that mind shift has helped me. So I don't want to be encouraging people to lean into that. I'm not going to eat mindset. But but that's that's different than looking than reframing fasting.
00:13:38.200Well, and I think it's important for people to understand that fasting just means you're eating less often. You're still eating.
00:13:44.960I do think that there is definitely and I see it on social media. There are certainly women that hide their eating disorder with intermittent under the guise of intermittent fasting.
00:13:54.240So, you know, when I when I talk to people about fasting, being very clear about who it's appropriate for and who it is not, but also making people understand that you are eventually going to break the fast, eat a good meal, probably eat a second meal, depending on the schedule that you embrace.
00:14:13.240But we are not suggesting that people starve themselves, that they not provide their bodies with sufficient nutrients.
00:14:20.200That's not what this is about. And much to your point, when we look at the ancestral health perspective, this is how our bodies are designed to thrive, because food scarcity was a real issue.
00:14:29.420So, you know, before there were supermarkets and grocery stores and convenience stores and ordering things on Amazon Prime that show up at your house the same day prior to that, you know, 150 plus years ago or even longer.
00:14:42.880Sometimes people, if they had a if they had a kill, maybe they they shot a deer and they they had meat and then they went through a period of time where they might have just had, you know, twigs and berries.
00:14:53.040And I'm not exaggerating that, you know, food scarcity was a real issue.
00:14:56.280So if our bodies weren't designed to be able to be fat adapted, if you will, tap into fat stores for energy, we would not have sustained.
00:15:05.760We would not have been able to survive.
00:15:07.200So on many levels, we've gotten. Yeah, we've gotten very comfortable as a society because we have quick access to food all the time.
00:15:15.400But that doesn't mean that we should be eating all the time.
00:15:17.880So I'm going to get to the plans that are available and like how you do it in one second.
00:15:22.020But I do want to ask you about metabolism, because, you know, we've all we've all been told you can't you can't go long periods without eating because it will slow down your metabolism.
00:15:32.600You have to have breakfast every day because that's what jumpstarts your metabolism for the day.
00:15:37.360Otherwise, your body thinks it's starving and it goes into starvation preservation mode where it lowers the number of calories it's going to burn and starts to protect you as though you're in the Arctic with zero access to food for the next two weeks.
00:15:49.860I believed that for a long, long time.
00:15:52.040And it wasn't until I started to do intermittent fasting that I was like, I don't understand the science, but that turns out to be BS because I can see the pounds coming off.
00:15:59.780Yeah, I mean, it's it's unfortunate that even as a health care professional, there are many of us that are still touting, you know, bad information.
00:16:08.340And we've really counseled our patients improperly with regard to meal frequency.
00:16:13.980And so I think one of the things that's really interesting is that when people start fasting as it pertains to metabolism, is that we get these secretion of counter regulatory hormones that will help suppress that hunger cue.
00:16:28.420So you're not going to feel like you're starving.
00:16:29.880And much to your point, you said, you know, I didn't think I would be able to do this at first.
00:16:33.180And I actually started to feel really good.
00:16:34.940And that's done for a number of reasons.
00:16:38.600You know, we know that, you know, one of the other things that happens while we're fasted is we get secretion of a hormone called growth hormone.
00:16:45.820And, you know, that really is potentiated when we are fasting.
00:16:51.220And so on many levels, I like what you said, growth hormone, which, you know, helps us maintain muscle.
00:16:56.760So the more muscle mass we have, the more calories we're able to actually consume or macros, depending on how you want to look at it.
00:17:04.360And that in and of itself helps with our metabolism.
00:17:07.760So I always like to remind people that our body is very smart and, you know, has the ability to flex in and out, meaning that if we're eating less frequently, but we're still getting a proper amount of macronutrients in during our feeding window,
00:17:22.580we're actually making our body more efficient, more fuel efficient, we're actually supporting that metabolism as opposed to making it harder to work.
00:17:30.980It's almost like we put more fuel efficient gas in our car.
00:17:35.080And on many levels, I think that a lot of people, until they actually practice intermittent fasting, they don't fully understand that.
00:17:41.740But the mechanics of our body really get gunked up if we're eating too frequently.
00:17:46.980And that can make the metabolism piece have to work a whole lot harder, be a whole lot less efficient.
00:17:51.320And if you're getting closer to, you know, 40s and beyond, you'll start to realize that things are not working as efficiently as they once did.
00:18:00.580All right. Up next, what are the plans that are available to you?
00:18:04.340What how can you do intermittent fasting and what are the most popular ways?
00:18:42.620Like what are let's go through maybe the top three most popular plans and what would be like the most popular you think that people are doing?
00:18:50.340I would think right now, I think it's probably between like a 16, eight or an 18, six, which means 16 hours or 18 hours fasted with a six or an eight hour feeding window.
00:19:01.040I see a lot of people doing OMAD, which is one meal a day.
00:19:04.540And that seems to be popular for a variety of reasons.
00:19:07.720And I have some concerns about that long term.
00:19:10.360But I would say those are probably the two most popular, I think, because they're accessible.
00:19:14.600I think it's harder for people to wrap their heads around doing every other day fasting, per se, or doing a 5-2, which generally means people are consuming a normal meal frequency over five days.
00:19:28.540And then two days, they have what I refer to as a subcaloric deficit, a significant one for men.
00:19:35.240It's less than 600 calories per day and women less than 500.
00:19:38.860So I think that the 16, eight or 18, six and the OMAD seem to be what's most popular, certainly with my own clients and, you know, people that I interact with online.
00:19:48.920So I do the 16, eight and I really like it because I stop eating at 8 p.m. and then I can eat again at noon.
00:19:55.900And for me and my own lifestyle, that works perfectly.