The Peter Attia Drive - March 24, 2025


#341 - Overcoming insomnia: improving sleep hygiene and treating disordered sleep with cognitive behavioral therapy for insomnia | Ashley Mason, Ph.D.


Episode Stats

Length

2 hours and 5 minutes

Words per Minute

208.256

Word Count

26,069

Sentence Count

1,891

Misogynist Sentences

5

Hate Speech Sentences

3


Summary

Ashley Mason is an associate professor at UCSF where she leads the Sleep, Eating, and Affect Laboratory. Her research focuses on non-pharmacologic interventions for mental health, particularly exploring how treatments like whole-body hyperthermia and mindfulness-based approaches can improve mood disorders, sleep, and eating behaviors. She s also the Director of UCSF's Center for Obesity Assessment, Study and Treatment, known as COAST. Her work integrates clinical psychology with integrative medicine, aiming to develop accessible treatments that address the biological and behavioral aspects of health. In this episode, we focus almost entirely around one area of her expertise, which is Cognitive Behavioral Therapy for Insomnia, or CBTI.


Transcript

00:00:00.000 Hey, everyone. Welcome to the Drive podcast. I'm your host, Peter Atiyah. This podcast,
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00:00:53.200 of the subscription. If you want to learn more about the benefits of our premium membership,
00:00:58.000 head over to peteratiyahmd.com forward slash subscribe. My guest this week is Ashley Mason.
00:01:06.460 Ashley is an associate professor at UCSF, where she leads the Sleep, Eating, and Affect Laboratory.
00:01:12.860 Her research focuses on non-pharmacologic interventions for mental health, particularly
00:01:17.180 exploring how treatments like whole body hyperthermia, mindfulness-based approaches can
00:01:21.720 improve mood disorders, sleep, and eating behaviors. She's also the director of UCSF's Center for
00:01:27.400 Obesity Assessment, Study, and Treatment, known as COAST. Her work integrates clinical psychology
00:01:34.180 with integrative medicine, aiming to develop accessible treatments that address the biological
00:01:38.860 and behavioral aspects of health. In this episode, we focus almost entirely around one area of her
00:01:45.900 expertise, which is Cognitive Behavioral Therapy for Insomnia, or CBTI. Ashley gives us a masterclass
00:01:52.880 exploration of CBTI, including various methods, including time in bed restriction, stimulus control,
00:01:59.200 and cognitive restructuring to combat insomnia. We speak about how to manage racing thoughts and
00:02:04.100 anxiety, and Ashley shares techniques like scheduled worry time to address stress during the day and
00:02:10.900 prevent sleep disruption at night. We talk about the impact of temperature regulation and the role
00:02:15.980 of warming extremities and optimizing sleep environments for effective sleep onset. We
00:02:20.940 discuss behavioral and cognitive interventions and the impact of leveraging small, actionable changes
00:02:26.800 in thoughts, feelings, and behaviors to overcome patterns of insomnia and other mental health
00:02:31.640 challenges. Ashley shares some sleep hygiene fundamentals addressing blue light exposure, food, and alcohol
00:02:38.040 intake, and creating bedtime routines for better sleep. She provides practical tools for tracking
00:02:43.220 progress, like using sleep diaries and A-B testing to identify and refine effective interventions. And we
00:02:49.660 explore the potential for AI and digital tools to democratize access to CBTI and address the growing
00:02:55.240 demand for sleep therapy. So without further delay, please enjoy my conversation with Dr. Ashley Mason.
00:03:01.120 Hey, Ashley, thank you so much for coming to Austin to talk about a lot of interesting things. Let's start
00:03:12.100 with the one that I think everybody listening can probably relate to at least once, which is insomnia.
00:03:17.780 Where did your interest in insomnia arise?
00:03:20.460 Well, I've been interested in sleep for a long time. I was fortunate to go to the University of Arizona for
00:03:26.160 my doctoral work. When I was there, the late Dick Bootson was also there. And he's one of the co-inventors
00:03:32.420 of cognitive behavioral therapy for insomnia. And I think I found it particularly interesting because
00:03:38.420 it works so well. We have so many different psychological treatments, and they all have varying
00:03:44.700 degrees of efficacy and effectiveness. And the thing about cognitive behavioral therapy for insomnia is that
00:03:50.200 it's kind of like a recipe. If you do it, it works. And this was always just so interesting to me because
00:03:59.020 it was so different than so many other psychotherapies out there that had just so much more unpredictable
00:04:03.820 outcomes. I would say that I became much more interested in it after my postdoctoral work when
00:04:12.680 I'd gotten to UCSF. I was a postdoc at UCSF, but I started my assistant professorship at UCSF.
00:04:18.620 And there was this gaping hole in treatment availabilities for people with insomnia. And I thought,
00:04:24.860 oh, this might be a good way for me to get back into some clinical work. I was doing just research at the
00:04:28.940 time. I fell back in love with it because there's almost nothing as rewarding as being able to see a
00:04:35.100 patient seven times. And that seventh time, have them say something to you along the lines of, have my life
00:04:41.640 back. I'm going to go get my driver's license back. I'm not afraid to drive with my kids in the car
00:04:46.620 anymore. I'm going to go back to work. I have my life back. Not much better than that. And so I grew
00:04:53.720 the clinic that I do CBTI in. And now I just love it so much that I do it on top of my job. Like I do
00:05:00.900 it at night with patients after hours because it's the most rewarding thing and you can have such a big
00:05:06.060 impact and people need it.
00:05:07.960 Before we dive into what CBTI is and how it works and how profound it can be, let's maybe help folks
00:05:15.780 understand a little bit about insomnia and maybe go through some of the definitions around the
00:05:21.140 different types of insomnia and maybe some of the different causes for it and maybe even what some of
00:05:26.820 the other treatments are, pharmacologic and otherwise.
00:05:28.860 Broadly speaking, most people at some point in their lives are going to have an issue with
00:05:34.080 insomnia. I think some 90% of adults at some point are going to struggle with insomnia and point
00:05:39.940 estimates I think at any given moment might be between 5 and 10%. The interesting thing about
00:05:45.220 insomnia is that it's a very clinical diagnosis. There's no blood test for insomnia. We can't put
00:05:51.560 you in a sleep lab overnight and do a test to see if you have insomnia. And we don't diagnose
00:05:57.880 insomnia based on one night of bad sleep. If someone says, oh, I didn't sleep at all last night or I
00:06:03.020 haven't slept even for just the last week, that's not going to get you a diagnosis of insomnia.
00:06:07.320 And there's a whole suite of different insomnias that we could talk about. But I think the point
00:06:14.300 that is the most salient is just that when you have a problem sleeping and when it's been going on for a
00:06:19.340 long time, at least like three-ish months, when you really feel it's a problem, that's when it's time
00:06:25.340 to get help. Because there's plenty of people who don't sleep a whole lot, but it's not distressing to
00:06:31.820 them. It's not causing any problems in their life. They're not going to meet a definition of
00:06:36.480 insomnia per se. It's the folks who will tell you that I can't sleep. I haven't been sleeping for
00:06:43.020 months. It's interfering with my life. It's really upsetting. And they've probably already started
00:06:48.940 trying a whole bunch of things to try and help themselves to fix it. And this is where things get
00:06:53.040 interesting. And just to be clear, Ashley, when you say that a point estimate of 5 to 10% of the
00:06:59.200 population would have insomnia at any point in time, you mean according to that definition where
00:07:05.100 it's been going on for months, it's causing distress, and it's impacting life?
00:07:08.860 Yeah, broadly speaking.
00:07:09.880 So it's low-end 1 in 20, high-end 1 in 10 people, adults?
00:07:13.960 Adults, yes. By the way, I do not do pediatrics, so please assume everything we're talking about
00:07:18.580 today is adults.
00:07:20.120 So that's a higher estimate than I would have guessed, given your definition. If the definition
00:07:24.740 was three nights of bad sleep, I would say, yeah, that makes sense.
00:07:27.920 Yeah. That's at any given point in time. Insomnia is, for most people, probably quite episodic.
00:07:34.980 It's not necessarily a permanent state. People go in and out of it. And the question is,
00:07:39.680 how quickly do people go out of it when they go in it? And that's what CBTI is so beautiful for.
00:07:44.860 It's helping people get out of it quickly. There's going to be things in your life that are going to
00:07:48.860 just happen, and they're going to put you over the threshold for insomnia. So maybe we can talk for a
00:07:53.740 minute about how insomnia begins and then how it's perpetuated, because these things are actually
00:07:57.600 quite different. So you and I and everybody have a certain level of predisposing factors that are
00:08:03.520 going to put us at risk for having sleeping problems, in particular insomnia. Then we may
00:08:09.520 experience what's called a precipitating factor. That could be a major life event like losing your
00:08:16.080 job, getting a divorce, getting in a car accident, some major unexpected unhappy life event that might
00:08:22.740 throw you into a bout of insomnia. That event will end, though. That event ends. The car accident
00:08:28.200 ends. It resolves. The job loss ends. You get a new job or you don't. The divorce ends. You move on.
00:08:34.660 But in the meantime, when you're dealing with that event, you develop behaviors to cope with it.
00:08:40.340 And so you might, for example, pop a Benadryl to help you sleep or an Ambien, something stronger.
00:08:45.440 You might start taking naps the next day after a bad night of sleep to try and cope with it.
00:08:49.820 You might start reading in bed a lot or flipping through your smartphone in bed. Doing all these
00:08:55.920 different types of behaviors to try and help yourself calm down and actually get to sleep,
00:08:59.140 which in the short term make a lot of sense. You're trying to help yourself in the acute moment.
00:09:04.300 But in the long term, these kinds of behaviors aren't actually doing you any favors. And over time,
00:09:11.060 that precipitating factor is going to go away. But all of these behaviors that you've started doing
00:09:16.620 to respond to the precipitating event, they're what stick around. And those are what are going
00:09:21.520 to perpetuate insomnia symptoms and problems. Can you say more about the predisposing factors?
00:09:26.940 Are those genetic? So there's, of course, genetic predisposing factors. I've had patients come and
00:09:33.920 say, I'm a really light sleeper. Can you fix that? That's going to be pretty tough to fix. I'm going to
00:09:39.280 recommend something like earplugs, an eye mask, a white noise machine, what have you. But yes,
00:09:44.560 there are going to be predisposing factors. So if you are higher on the general psychological
00:09:50.980 reactivity, you're going to probably get pushed over the threshold more easily than someone else.
00:09:57.080 Some people might get in a car accident, a fender bender, and they're over it by the next day. The
00:10:00.900 car's in the shop, whatever. Other people might feel antsy about driving for a while after that.
00:10:06.640 They might feel more anxious as a result of that event. And that's going to differ from person to
00:10:11.080 person. You can argue that that's genetic. You can argue that that's based on early childhood or
00:10:16.800 other experiences. But nature and nurture probably both contribute to that predisposition. And there's
00:10:23.060 not a whole lot that we can do about that. But this is the beauty of cognitive behavioral therapy
00:10:27.680 for insomnia. When people come in for treatment, they're often pretty focused on what caused their
00:10:35.420 insomnia. And I actually don't ask people what caused their insomnia until the end of my first
00:10:40.580 session with them. I'm asking them all these other kinds of questions about their behaviors now.
00:10:44.600 And at the end, I ask, okay, so when did this start? What do you think might have caused this?
00:10:51.280 And get their attribution for what's going on. Because at the end of the day, the intervention's
00:10:55.480 the same. And that's what's beautiful about this and might differ a lot from the practice of
00:11:00.660 medicine. I'm not an MD. I'm a PhD. I think in a lot of disease states, we often look at what caused
00:11:06.000 what's going on. I'm not really concerned. I'm more concerned about what you're doing now that's
00:11:11.060 perpetuating the problem. And that's where I intervene. And that's why this particular treatment
00:11:15.840 is so effective for so many different presentations of insomnia and causes of insomnia. Whether people
00:11:23.240 have difficulty falling asleep in the beginning of the night, waking up in the middle of the night,
00:11:27.400 waking up too early in the morning, you might think on their face, these people all need
00:11:31.700 wildly different treatment. But that's not actually the case.
00:11:35.400 Yeah, that makes a lot of sense. So the focus is much more on the coping strategy and the behavior
00:11:40.980 that came out of the predisposing factor or the precipitating event actually is really...
00:11:45.560 Used to respond to the precipitating effect. Exactly.
00:11:48.160 Okay. Can we talk a little bit about, is there a difference, for example, between the individual
00:11:53.060 who can't fall asleep, this initiation of sleep insomnia versus the person that I hear much more
00:11:59.580 about, frankly, I experience more, which is, it's not that hard for me to fall asleep, but boy,
00:12:06.160 I will jolt up at one in the morning with some thought or anxiety that I can't get out of my mind
00:12:14.300 and my mind starts running and I can't go back to sleep. Or I get up because I got to pee,
00:12:18.800 but when I come back, I erroneously just do something with my mind where I get thinking
00:12:25.960 about the day's problem or whatever, whatever. Do you think of those as difference or the
00:12:29.800 different side, same coin, I guess?
00:12:31.700 Those people need the same stuff. And the people who can't fall asleep at the beginning of the night,
00:12:37.320 their mind's just racing earlier than yours. Yours is just waking you up. And there's a whole
00:12:42.620 suite of interventions that are part of cognitive behavioral therapy for insomnia.
00:12:47.140 There are a lot of ways that I could approach an answer to this question. So I think starting by
00:12:53.360 addressing the racing mind issue. I always tell patients, if you don't deal with what's causing
00:12:59.360 you stress or anxiety during the day, it's going to demand to be dealt with in the middle of the
00:13:03.700 night. It's going to say, oh, Peter, I noticed you're laying there peacefully, not doing any work
00:13:08.700 or tasks and you don't have anything you need to do right now. So you're going to pay attention to me
00:13:12.320 and it's going to demand your attention at that time. Other people, that happens right when their
00:13:16.680 head hits the pill at the beginning of the night. Oh, you're relaxing now. Okay, here's your 10
00:13:20.040 things to worry about. So one of my favorite interventions that's actually born of anxiety
00:13:25.340 treatment, but that I've co-opted and I've moved into cognitive behavioral therapy for insomnia because
00:13:31.040 it fits with the theoretical framework is something called scheduled worry time. This sounds a little
00:13:37.300 bit pedantic and silly, but hear me out. If a patient came to me and said, Ashley, I worry all
00:13:43.760 day. I'm worried about all of these things. My life is just a constant ball of worry. And I said,
00:13:48.580 okay, I've got a solution for you. And it's two words. Ready? Stop it. That wouldn't work.
00:13:56.100 It doesn't work. I take the opposite approach. Okay. This is really important to you. This is
00:14:00.620 something you're doing all the time, all day. Guess what? What do we do with things that are really
00:14:04.060 important to us? Make time for them. We schedule them. Exactly. Back in the day of paper calendars,
00:14:09.520 this felt like a different exercise. Now people get out their phones, but I have them get out their
00:14:14.300 phone or whatever and say, all right, we're going to schedule worry time. And it's going to be an
00:14:18.040 hour a day for the next seven days. It is non-negotiable. I may or may not schedule an email
00:14:24.520 to go out to you at the end of that time. And you have to go and reply to it and tell me what you did.
00:14:29.460 And what we find is that when people work with this during the day, it does two things.
00:14:35.000 The first is, let's say it's 9am and you are trying to do something in your life and instead
00:14:41.640 a worry pops up. You can actually think, oh, okay, I don't have to deal with this now. I'm
00:14:45.780 going to write this down because at four o'clock I've got scheduled time to deal with this.
00:14:49.720 So that way you're uncluttering the rest of your day by moving all of the worry into that scheduled
00:14:55.500 time. So this could be a valuable technique, even absent insomnia.
00:15:00.000 Totally. I'd say that probably between a third and half of my patients who come in with insomnia,
00:15:04.760 they've got some bad sleep stuff for sure. But for some of those people, it's a primary anxiety
00:15:09.760 disorder and sleep is suffering also. Whereas other folks, it's primary insomnia and that's
00:15:16.060 driving them anxious. But to rewind back to your earlier question about the middle of the night
00:15:20.680 versus the beginning of the night. So the other thing that scheduling worry time does besides
00:15:24.680 uncluttering your whole day is it helps you get it done during the day so that when your
00:15:29.040 head hits the pillow, it's not there. Oh, I already worked on this. And also the knowledge,
00:15:34.680 oh, I have time set aside tomorrow to work on this or to think about this. So I don't have to do that
00:15:40.560 now. Cognitively, this all makes sense and you would maybe think you can think your way out of
00:15:45.340 this, but you can't. You actually have to try it. And I've done this with a lot of people.
00:15:51.560 I've done this with doctors, police people, people from all walks of life can really find this
00:15:59.420 valuable. The other thing when it comes to falling asleep at the beginning of the night versus the
00:16:04.420 middle of the night is that there's sometimes low hanging fruit that we can think about.
00:16:09.460 You mentioned getting up to go to the bathroom. I've found that for a lot of men who are 45 and
00:16:15.320 up who still have a prostate, just not drinking very much fluid with dinner and after dinner is
00:16:21.500 huge. And also throwing an electrolyte tab in there can really help. Granted, it's got to be
00:16:27.740 the right osmolarity and everything else, but there are ways to find this. Don't slam Gatorade at night.
00:16:32.060 That's not what I'm suggesting, but just throw a noon tab or whatever element, whatever electrolyte
00:16:38.000 replacement. I've had some male patients go from waking up three times in the night to pee to one time.
00:16:44.540 And the fewer times you wake up in the night, the fewer times you risk not falling back asleep.
00:16:50.280 So little things like that can actually make a difference for waking up in the middle of the
00:16:54.820 night. The other one I have about the middle of the night is a little more out there, but hear me
00:16:59.740 out. If I had five cents for every time I took away a down comforter from someone and their sleep got
00:17:07.760 better, I'd have like $8. I mean, this is huge. And this is because everybody's heard of circadian rhythm,
00:17:13.520 but it's missing a word. Circadian temperature rhythm. Your body is supposed to be its coolest
00:17:19.380 at night and its warmest during the day. And my favorite people to talk with about this are
00:17:23.660 actually anesthesiologists. They know more about body temperature than anyone. It's remarkable.
00:17:29.620 But what I've had the great good fortune of learning is that your body temperature,
00:17:34.600 it's supposed to be the warmest during the day and the coolest during the night.
00:17:36.720 When we do things like trap heat with down comforters, quilted nonsense, even cotton replacement,
00:17:45.700 if the word duvet is in it, comforter is in it, it's a no for me. And I give people a handout. I'm
00:17:51.360 like, here's the definition of a cotton blanket. Here are links to examples of what cotton blankets
00:17:55.140 are. If you are cold, buy two, buy three, use these. And I'm telling you, it's made a huge difference
00:18:03.780 for a lot of women in particular with night sweats. And people wake up less sometimes because they're
00:18:09.980 not giving their body this message that it's time to wake up because they're not as warm.
00:18:14.240 People complain about their feet and their hands. And I say, that's fine. You can put your down
00:18:17.520 comforter over the foot of your bed. You can wear some socks. But I take body temperature regulation
00:18:24.460 very seriously. And sometimes it's a quick fix and we don't need a whole lot of muss and fuss.
00:18:29.380 This is a very long word to answer your question, but I'll finish after this. The people at the
00:18:33.400 start of the night, it's worth asking people at the start of the night if they're cold,
00:18:37.200 if their hands and their feet are cold. Have you ever tried to fall asleep when your hands and
00:18:40.180 your feet are cold? Yeah. I try to be uncomfortably cold when I get into bed.
00:18:44.120 Right. But your hands and your feet? No, generally not. I mean, it's just my body. But again,
00:18:48.760 I'm using a device to cool me as well. Slightly different. But spoiler alert, it's pretty hard to fall
00:18:54.300 asleep when you have cold hands and feet. And what we have data on from some interesting
00:18:58.360 research in a totally different realm is that people with extremity circulation disorders who
00:19:03.940 have really cold hands or something like that. Yeah. They will have what we call early insomnia,
00:19:08.380 which is difficulty falling asleep at the beginning of the night. And when they get successful treatment
00:19:12.460 or when you warm their hands and their feet, much easier to fall asleep. The whole warm foot bath
00:19:17.420 before bed thing, that's an actual thing. Your extremities help you dump heat. So when you actually
00:19:23.360 warm your hands and your feet, you can actually help dump heat from your core because you're
00:19:27.340 vasodilating. And when you fall asleep, you want to be dumping heat from your core. Hard to do that
00:19:32.560 when you're vasoconstricted in your hands and your feet. So for folks who have trouble falling asleep
00:19:36.700 at the start of the night, we want to make sure their hands or feet are warm enough and that they've
00:19:40.900 dealt with the thoughts and the worries during the day and that they're not trying to go to sleep at
00:19:45.980 nine o'clock when their body doesn't want to go to sleep until 11. A lot of people just think,
00:19:50.220 I need to have this much time in bed each night. And they get into bed and they struggle for two
00:19:54.800 hours before their body actually wants to go to sleep. So a major part of CBTI is aligning when
00:20:00.560 your body can produce sleep with when you're in your bed. I want to kind of go into many more of
00:20:05.700 these because I know this is the exciting stuff that people are interested to hear about. I do want
00:20:09.200 to take one step back and just make sure we understand what constitutes cognitive behavioral therapy
00:20:14.500 before we even get into cognitive behavioral therapy for insomnia. So we've had a podcast where we
00:20:18.720 talked about dialectical behavioral therapy, DBT, but we haven't covered CBT. Can you give us a little
00:20:24.760 bit of the tapestry of what defines it and why it of course then has this additional subset of
00:20:32.220 treatment for insomnia? I should have done that first. Cognitive behavioral therapy, my favorite way to
00:20:37.660 think about this is in a triangle. We have thoughts, we have feelings, and we have behaviors. You can think
00:20:43.400 about this triangle as having these three pieces that are all connected. And cognitive and behavioral
00:20:49.600 therapies or cognitive behavioral therapies generally will focus on one intervening on this
00:20:55.500 process between thoughts, feelings, and behavior, thoughts, feelings, and behavior on one of these
00:20:59.780 sides of the triangle. So let me just spell out a quick example process. So let's say we have a patient
00:21:05.980 with type 2 diabetes who has the thought, I'm never going to be able to get my blood sugar under
00:21:11.920 control. I'm never going to be able to manage this. I'm not going to be able to do this. When a person
00:21:16.180 has those thoughts, how do they feel? Crummy, feel bad about themselves. When people feel bad about
00:21:20.480 themselves, what do they do? Eat some chocolate cake. Eat some chocolate cake. What does that do? That
00:21:24.780 reinforces the thought, I'm never going to be able to do this. So we've got this pattern of thoughts,
00:21:28.760 feelings, behavior on repeat. Cognitive behavioral therapies will choose where to intervene on a process in that
00:21:35.480 triangle. Cognitive behavioral therapy for insomnia, for example, is really focused on the area between
00:21:41.500 thoughts and feelings in many ways, because people will have a lot of thoughts. I can't sleep. I'm never
00:21:47.240 going to be a good sleeper. If I don't sleep eight hours tonight, I'm going to lose my job, whatever.
00:21:52.680 And then the big emotions that follow from that. We work on questioning a lot of those thoughts to then
00:21:57.840 recalibrate the feelings that follow. Like, oh, if I don't sleep eight hours tonight, I won't feel great
00:22:02.480 tomorrow, but I'll probably be okay at work. The feeling is much smaller than, if I don't sleep
00:22:07.140 eight hours tonight, I'm going to lose my job tomorrow. They're noticeably different. In terms
00:22:11.840 of depression, an example that I like might be someone saying, oh, I'm really depressed now, but
00:22:17.800 when I feel better, I'm going to take my grandkids to the movies. That's what I'm going to do. I'm going
00:22:22.540 to take my grandkids to the movies. I'm going to take them to the zoo. I'm going to do all these
00:22:26.500 things. So as a therapist, what I might do is I'd have the patient write all of this huge long list of
00:22:31.900 stuff they're going to do when they feel better. And then you know what I'm going to do. I'm going
00:22:35.400 to get out their calendar with them and I'm going to say, all right, I don't care how you feel.
00:22:39.580 We're scheduling all of these things. So we're intervening on that behavior to thoughts line.
00:22:45.080 So we're going to make them take the kids to the zoo. We're going to make them take the kids to the
00:22:49.220 movies. And then the kids are going to have a great time. And the patient's going to come back
00:22:52.660 and say, oh, you know what? Pretty kick-ass grandma. Kids had a great time. This was pretty great.
00:22:57.260 So we're intervening on the behavior to change the thoughts about the self. Like, oh, I'm going
00:23:02.540 to do these things when I'm better. A major feature of cognitive behavioral therapies is
00:23:07.120 intervening on behavior to change thoughts, but also intervening on thoughts to change feelings.
00:23:13.920 And there's just many, many applications for this. Cognitive behavioral therapy has been adapted
00:23:19.120 for a whole host of disorders, for eating disorders, for insomnia, specifically for anxiety.
00:23:25.420 That's going to be more in the thoughts and feelings realm too.
00:23:28.740 Is that kind of running the triangle in the other direction? So you change behavior to change
00:23:33.800 thought, you change thought to change feeling?
00:23:36.040 Yeah. So you can change thought to change feeling. You can work on behavior to change thought. You can
00:23:40.920 operate on any way of those with different techniques that have been just repackaged into different
00:23:47.120 therapies.
00:23:48.200 And tell me a little bit about the history of CBTI specifically. When did the idea come to
00:23:54.020 existence in a way that's been packaged more or less the way it is today?
00:23:58.360 Cognitive behavioral therapy for insomnia is actually old news. I mean, we can go back to
00:24:03.420 the 1970s. I remember when I was learning cognitive behavioral therapy for insomnia,
00:24:08.440 one of the most fun studies to read about was this study of, I believe it was college-aged men who were
00:24:16.020 not doing well academically. And the intervention that they did with them was one of the two pillars
00:24:22.800 of cognitive behavioral therapy for insomnia, which is called stimulus control. And what they did with
00:24:28.400 these young men is they told them, all right, you're going to be assigned a carol in the library.
00:24:33.020 And in this carol is the only place you can study. You can't study in your dorm. You can't study outside.
00:24:38.920 Can't study anywhere else. Just this carol. And only this amount of time can you study each day.
00:24:46.460 If you're on a roll, we don't care. You have to stop. If you're miserable, we don't care. You just
00:24:51.240 have to keep on doing whatever portion of the study over and over again that you're stuck on.
00:24:56.220 So they trained these young men to just study in that one place. And it succeeded in helping
00:25:03.700 these men. And these men were struggling with anxiety or actual insomnia? Academically. This is
00:25:08.800 just stimulus control, where we learn to associate a place with a behavior. And fast forward a little
00:25:17.080 bit. It was called the Bootsen method at one point for Dick Bootsen. But one of the hallmarks of
00:25:22.460 cognitive behavioral therapy for insomnia is your bed is only for sleep. There are two things you're
00:25:27.980 allowed to do in bed. I always tell my patients, your two things that you can do in bed are sex and sleep.
00:25:32.460 If you're not sure if something counts, message me and I'll clarify it for you real quick, whether it
00:25:37.320 counts in one of those two buckets. But we really want to just associate the bed with sleep.
00:25:44.140 And to be clear, just going back to this study, was there a belief or were some of these guys
00:25:48.740 studying in bed? They were studying in their dorms, in their beds and everywhere else. I mean,
00:25:53.480 everywhere. So this wasn't specifically a study focused on sleep per se. It was just focused on this
00:25:59.240 associative pattern that became the bedrock of this treatment. And we can go back even further
00:26:06.200 and we can look at Pavlovian conditioning, the dog and the bell and the food. And we don't need to go
00:26:11.200 over what that whole thing was again right now. But the point just is that the dog came to associate
00:26:15.920 the bell with getting food. And a lot of times when people are struggling with sleep, you know what
00:26:20.800 they're doing in their bed? They're reading, they're scrolling, they're watching TV, they're listening to
00:26:25.900 podcasts. They're doing like everything. A lot of people, by the time they get to me, they're camping
00:26:30.480 out in their bed just in case they're able to sleep. Oh, I'm going to go have a snack in bed because
00:26:34.280 if I'm sleepy enough, I'll roll over and take a nap and I'll get some extra Zs. So people have moved so
00:26:39.180 much of their lives into their beds that it's completely dissociated from sleep. That's one of
00:26:44.740 the bedrocks. And then another bedrock is what we now call time in bed restriction. This used to be
00:26:52.460 called sleep restriction. But I don't know where along the way in the last number of years it went
00:26:58.260 from being called sleep restriction to time in bed restriction. But whoever made the change, I'm still
00:27:02.600 not sure who made that change. I am thankful to them for it. Because the other key component of CBTI is
00:27:08.140 that we restrict the amount of time that a patient is in bed to match how much time their body can actually
00:27:15.020 produce of sleeping. A lot of times people with insomnia will say, okay, I need to be in bed for at least
00:27:19.960 12 hours if I want to get seven hours of sleep. I know it's hard to believe, but it's true. And we
00:27:26.620 just obliterate that notion. And this is another core and very old part of CBT that dates back, what,
00:27:33.860 1970s, 80s? But when you take those two parts, then you start to add in some of the cognitive
00:27:41.200 components that have been around also for decades. The cognitive therapies part, the Aaron Beck stuff with
00:27:46.980 cognitive restructuring, which is where we take a thought. Have you ever heard that phrase,
00:27:50.800 don't believe everything you think? So you take a thought, and on the classic thought record tool,
00:27:56.480 you'll have patients write down the thought, write down how they feel, rate their feelings from,
00:28:00.960 say, zero to 90%. And then we have them write down, what's the evidence for this thought?
00:28:05.560 If you had to go to court right now, and there was a judge and a jury and what have you,
00:28:10.640 and you had to present evidence for your thought, what would you be able to present?
00:28:14.660 Evidence for a thought is not another thought. It's not a belief. It's evidence. Last time I
00:28:20.440 slept six hours, I got a worst grade on a test or something. That would be evidence. You got a
00:28:26.920 worst grade on a test. But then we look at all the evidence for a thought, we look at all the
00:28:29.960 evidence against a thought. Like, oh, last time you didn't sleep so well, you didn't get fired,
00:28:35.900 still did fine in school, whatever the thing. And then we create a balanced thought, which is,
00:28:41.260 even though I'm not going to be as well rested, I'll still get through this day.
00:28:45.480 Then we have people re-rate their emotions, re-rate how much they believe this new thought,
00:28:49.400 this whole song and dance. This is the cognitive component. And that's kind of the bedrock of so
00:28:54.720 much of cognitive therapy. Of course, people have so many negative thoughts about sleep and
00:28:59.640 dysfunctional thoughts about sleep that aren't true or that are catastrophizing and whatnot.
00:29:04.160 That is also blended in to the treatment. And then we have relaxation techniques, which are
00:29:10.940 things like progressive muscle relaxation that came along as well. And those are part of the
00:29:15.520 treatment. Progressive muscle relaxation will be like where you squeeze your hands and let it go
00:29:19.500 and squeeze your hands and let it go and then squeeze your arms and let them go and move through
00:29:23.520 your whole body to get out of your head and into your body. And I don't know what order those
00:29:27.760 actually were packaged into CBTI. But I can tell you the first two, the stimulus control
00:29:34.160 and the time in bed restriction, those are among the earliest parts of CBTI. And what we know from
00:29:39.860 dismantling studies is when you take either of those out of the treatment, no dice.
00:29:45.520 Yeah. I want to talk about both those a little bit more. I want to bracket sleep hygiene and come
00:29:50.520 back to it because I think, again, the temperature and all that light stuff, we shouldn't gloss over
00:29:54.300 that even though it's easy to take for granted. And I know that many people listening to this podcast
00:29:58.620 will have heard other content where we talk about it, but I'd love to have it all in one place.
00:30:02.460 I think the time in bed restriction is pretty interesting. And in talking with sleep physicians
00:30:08.540 who also implement this, it seems quite draconian at the outset. It can be remarkably difficult.
00:30:16.860 They're giving people five hours in bed max and they're really trying to force sleep pressure.
00:30:22.700 How do you navigate that and how do you decide how hard to squeeze the tube of toothpaste?
00:30:26.740 Let me draw a line in the sand between what CBTI says broadly as a treatment and then how I've
00:30:32.740 actually implemented it in my clinic. So what CBTI will have you do is they will have you,
00:30:38.520 and I say you as the royal you, your patient, they will have you fill out something called a sleep
00:30:41.740 diary. And this is a paper diary that covers seven days. Because if I asked you how well you slept
00:30:48.420 four nights ago, you'd be like... It's like a food frequency questionnaire in epidemiology.
00:30:52.900 Totally. Total waste of time.
00:30:54.020 Total. So you have to do it every morning. Okay. And of course, I'm not obsessed with it being exact
00:30:59.720 because I'm much more interested in the picture pattern of it. If you asked someone to fill it
00:31:04.020 out for just one day and then worked with that, you'd have a totally distorted picture. You wouldn't
00:31:07.500 know what you're working with. But what classic CBTI does is they'll take that seven day sleep diary
00:31:12.200 and then they will actually use it. The time you got in bed, time you fell asleep, how many times you
00:31:17.460 woke up, how long you were awake, what time you woke up. It has all of these different questions
00:31:22.920 in it. And you can use that to calculate how much time a person was sleeping on average over the
00:31:29.180 course of the week. And what CBTI does is it says, you patient, why don't you pick what time you want
00:31:35.380 to get up every day? And then you would ostensibly pick a time. The CBTI clinician, let's say your sleep
00:31:41.500 blog said you were naturally sleeping six hours a night. The clinician would add 30 minutes to that
00:31:46.540 and make it six and a half hours and then work backwards from your chosen wake time.
00:31:51.200 So let's say you chose a wake time of 7 a.m. I would work back six and a half hours to get to a
00:31:58.100 bedtime for you of 1230 a.m. And of course, that's the bedtime of your childhood dreams. Imagine going
00:32:03.140 to a sleepover and your friend's mom saying, all right, kids, you can't go to bed until after 1230
00:32:08.660 a.m. Kids love it. Adults think this is torture because it is. That's what classic CBTI would do.
00:32:15.820 Six hours being the number?
00:32:17.300 Six and a half. You get that half hour of grace. As far as I know in CBTI, almost nobody's restricting
00:32:24.760 less than five and a half hours. Five and a half seems to be the floor. I've not seen people
00:32:29.800 restricting to five. There are a subset of people, and I don't know the data on this because I don't
00:32:35.260 even know if the data exists on this, who are what we call genetically short sleepers. And these
00:32:41.740 people know who they are. They have always been like this. And it's not upsetting and distressing
00:32:46.420 and causing them grief. We're not talking about those people. Okay, so that's what CBTI will do.
00:32:51.680 And just to be clear, let's say five and a half is the floor. Six is typically what you would do.
00:32:56.820 So six and a half in bed. Well, no. If your body is producing six hours of sleep, I add 30 and I get
00:33:02.820 six and a half. If your body is producing only five and a half, I add 30 and you get six. So I do this
00:33:08.900 computationally for each person. I see. So when I bring my sleep log to you, you've seen that for
00:33:14.700 the past week, I've been spending 12 hours in bed. But by my recollection, because I'm looking at the
00:33:20.580 clock when I'm not sleeping, I'm only getting six and a half hours of sleep in the 10 or 12 hours I'm
00:33:27.360 laying there, you're going to say, oh, okay, that's your sleep time. Take that, add 30. That's your time
00:33:32.280 in bed. I got it. Yes. Yes. And here's where what I do is slightly different, but also the whole
00:33:39.380 theoretical underpinning is not disturbed at all by the way that I do this. So how many times have you
00:33:44.480 had a patient come to you and say, oh, I really want to be that person who wakes up at 5 a.m.,
00:33:49.580 get to go on my day. I want to get my exercise in. I want to get my meal prep in, do all this stuff.
00:33:55.640 And you're like, oh, okay, cool, cool. So you want to be a five in prison. What time do you get up now?
00:33:59.280 Oh, like 11. And I'm like, oh, okay. All right. So this whole part in CBTI where people choose their
00:34:04.840 wake time, that's not a thing for me. In my clinic, we play a game called democracy within a dictatorship.
00:34:11.600 What that just means is that instead of just letting patients carte blanche choose their wake time,
00:34:16.360 I actually look at their sleep diary and I let them think they're choosing their wake time. And if I
00:34:20.280 agree with it, they will have chosen. If I don't, the dictator comes in and I look at their diary and
00:34:26.460 if they are getting up at 7 a.m., 6 a.m., 7 a.m., 7 a.m., 6 a.m., 6 a.m., 6 a.m. And they say to me,
00:34:35.460 oh, I want to wake up at 8.30. I will say, well, we have no evidence that you can sleep until 8.30.
00:34:40.900 That's not realistic. But we have evidence that you can sleep until 6 because four of the last
00:34:47.100 seven days, you made it until 6. So 6 o'clock is your wake time. And this is not anywhere in CBTI.
00:34:53.800 I've spoken with a lot of my colleagues who do CBTI and asked them, how do you choose a wake time? And
00:34:57.960 there is no standardized method. But by using this method, I'm definitely making sure that I'm at
00:35:04.080 least gating the patient's sleep at a reasonable time. Because if I let that patient just choose 8.30 a.m.
00:35:08.860 as their wake time, and they were only producing six and a half hours of sleep.
00:35:13.200 They're going to bed at one in the morning.
00:35:14.680 They're going to bed at two in the morning, and they're getting up at 8.30 because they chose their
00:35:19.440 wake time as 8.30. But really, they're going to wake up at like six or seven, and they're not even
00:35:23.100 going to cash in on the full six and a half hours that they should be getting a bed. So I've added in
00:35:28.540 this component of my own of setting their wake time to be a much more reasonable time. And then what I do
00:35:35.500 before giving them a bedtime, I give them a week at that wake time. And I see how much sleep is your
00:35:40.680 body producing with this new wake time. Now, let's say you're doing the sleep log, and they're
00:35:47.040 spending, you know, eight hours in bed, getting four hours of sleep. Let's say they're getting
00:35:53.420 five hours of sleep, eight hours in bed, and then they're taking an hour nap a day. So they're
00:35:59.940 removing all their sleep pressure during the day by taking that nap, but they kind of need to take the
00:36:03.960 nap because they're not getting enough sleep. So they're in this vicious cycle. So do you add the
00:36:08.040 hour of nap time back to sleep and say, actually, you're getting six hours of sleep. Let's do the
00:36:13.440 exercise based on five plus one plus a half, 6.5? No, no, no, no, no, no, no. We want to extinguish
00:36:18.660 that sleeping during the day thing. So there's a difference between a person without insomnia
00:36:23.160 healthily using naps, and then there's a person with insomnia who's napping to compensate for what's
00:36:28.520 not happening at night. So I think that to best explain this, I should just finish this example
00:36:33.480 of the wake time thing because this directly ties in. If I'm setting their wake time and then I'm
00:36:38.480 seeing how much time they're actually producing sleep, that first week when I give them the wake
00:36:42.020 time, I don't give them a bedtime. I don't even do time in bed restriction that first week because
00:36:46.580 for some people, setting a wake time solves the issue, which is kind of nuts. But one or two of every
00:36:54.000 eight patients who I see, because I see patients in groups of eight, will have a huge improvement
00:36:58.460 from just having a consistent wake time because their body actually recalibrates and they start
00:37:03.600 getting sleepy at a more consistent time each night because they're not doing that. And I do say in that
00:37:08.740 first week, I take away the naps. I say, I don't care how you slept last night. You need to just stay
00:37:12.900 awake until you're ready to go to sleep. No naps for now. Now, when I have patients, probably older
00:37:20.220 patients, like 80 and up, I'll be okay with a nap, but I'll often, at this stage, I'll say, look,
00:37:27.040 you have an opportunity of 25 minutes. And a 25-minute nap opportunity means you set the alarm
00:37:33.000 for 25 minutes, you get in bed, and it's going to go off 25 minutes later, and that's when you get up.
00:37:37.000 I don't care how long you actually slept during that time because I don't want you going into
00:37:41.240 phase three or phase four slow wave deep sleep during the day because that's what's going to really
00:37:47.240 mess you up at night. A stage two sleep nap is not really an issue during the day as much. It's
00:37:54.260 not going to be so bad. But at this stage of the person with insomnia that we're talking about,
00:37:58.520 I don't want them taking a one-hour nap in the day. And they come back that second week having
00:38:03.020 done the wake time that I said, and I then recompute how much time in bed they're spending.
00:38:07.360 And then I still use that wake time, and I then calculate their bedtime. And then the true time
00:38:13.240 to bed restriction begins week two. Okay. But just to be clear, if you have someone who is using a nap
00:38:19.580 to compensate for their insomnia, step one is just kill the nap. Kill the nap. And then let the cards
00:38:25.820 settle where they may for a week, recalculate actual sleep time, and then go through the exercises
00:38:31.560 described. I've made this point on a podcast before, I think, but just want to get your blessing.
00:38:37.860 When we're on bow hunting trips, you are going to bed insanely late and waking up insanely early.
00:38:45.380 It's just the nature of when you get back to camp and eating, and then you got to be up super early.
00:38:50.140 So I've never been on one of these trips where I could actually be in bed for more than five and a
00:38:55.380 half, six hours in a night. So the strategy is to get that sleep, but then I always try to get a 90
00:39:02.000 minute nap at around one in the afternoon. And the reason I pick 90 is to get a full sleep cycle.
00:39:09.560 And I tend to function incredibly well under those circumstances, because remember, you're also very
00:39:13.640 physically active. Like this is demanding time. So would I be better off not doing that nap midday?
00:39:19.760 Oh, that's a bow hunting trip and you don't have insomnia. That's not a problem.
00:39:22.920 Okay. All right. Got it.
00:39:23.880 Yeah. Totally different monster. And I tell people too, a lot of the last few years,
00:39:28.380 people have had serious illnesses. They've had COVID, they've had whatever. When you're sick,
00:39:32.320 all bets are off. What I tell people is, if you need a nap when you're sick, you need a nap when
00:39:35.900 you're sick, but we maintain stimulus control. You don't nap on the couch. We're only napping in bed.
00:39:41.220 And if you're awake and feeling sick, then you can be on the couch, not in bed.
00:39:45.480 While we're on that topic, what do you say to the legions of people watching who
00:39:50.060 fall asleep watching TV on the couch?
00:39:52.300 Oh, the worst. A lot of people fall asleep on the couch because they're just so overtired
00:39:59.920 that the ship has sailed. Their body's ready to go to bed and they're just letting it and they're
00:40:05.340 not getting up and doing the thing. I tell people, look, if you want to prioritize your sleep,
00:40:10.680 pay attention to your body. When you're watching TV, do you notice that you're starting to nod off?
00:40:15.060 Do you notice your eyelids feeling heavier? Your hands feeling warm? Are you starting to sag a little
00:40:18.720 bit? Okay. These are indicators that it's probably time to get off the couch and go to bed. For people
00:40:24.800 who can't figure that out, I say, okay, you want to watch TV at night? Sit in a stool. You're going
00:40:28.440 to figure it out real fast.
00:40:30.400 What about just the social dynamic of it, which is when you have a couple, not that I'm saying this
00:40:35.100 from experience at all, and one part of that couple, they want to be together and watch TV,
00:40:41.140 but one member of that team falls asleep immediately while the other does not.
00:40:47.000 And the one that does not tries to tell the one that is to go to bed, but that one wants to be
00:40:53.400 with the other. I don't know if you can ever imagine a scenario like that.
00:40:56.440 Yeah.
00:40:56.940 I'm just making it up.
00:40:58.580 Okay, good. I'm glad you're making that one up. I have a lot of these couple level issues that come
00:41:02.320 up in sleep clinic. This is not uncommon because what's more intimate than being completely
00:41:07.600 unconscious next to another person. If you think about it evolutionarily, that's probably the
00:41:12.320 riskiest thing you can do. So there is this desire for closeness in lots of couples, and it
00:41:17.840 becomes a challenge when one of the members of the couple has a sleep problem. And the first step is
00:41:22.460 remembering this is not necessarily permanent. We need to go about fixing this now, and then we can
00:41:27.240 find a new winning solution. So in the interim, I'm assuming you've already tried maybe watching
00:41:34.100 something different on TV that might be more exciting to the second partner, et cetera. It's not
00:41:39.140 about the boringness of the show per se. Doesn't appear to be.
00:41:42.380 Okay, good. So if that's the issue, then I would say, hey, if this is a priority, what are we going
00:41:47.900 to do? We're going to schedule it. We're going to schedule time to be on the couch together at a time
00:41:52.620 when I can definitely be awake and be spending meaningful time with you.
00:41:56.100 The problem is sometimes other members of the family who tend to be smaller also tend to be
00:42:03.900 occupying all of the bandwidth during those earlier hours when the member of the family in
00:42:11.700 question is able to be awake. This is a hard problem to scale. But what I would just say is
00:42:17.740 if you're actually ready to go to bed and your body is saying that you need to sleep, you should
00:42:23.600 probably do that. It's more likely that then you'll be awake the next day and be a more pleasant,
00:42:30.260 exciting partner to be around and be able to have more meaningful experiences with your partner
00:42:36.800 that way. Otherwise, I tell people, look, this is an issue. If it's really an issue, we're going to
00:42:41.240 get a babysitter. Figure it out. There are ways to get around these things. People just often want it
00:42:47.820 to work like they see in the movies. Like, oh, this should be easy.
00:42:51.500 Obviously, I'm talking about my wife here, so I'll stop double speaking. But if my wife falls asleep
00:42:56.420 every single time on the couch, but then when said Netflix is over and we go up to bed,
00:43:02.000 she falls right back asleep and it doesn't seem to keep her awake, is it pathologic?
00:43:07.900 This isn't necessarily a problem. But what I would say is we sleep more deeply at the beginning of
00:43:12.380 the night. We experience more slow wave sleep in the first half of the night and more REM sleep in
00:43:16.880 the second half of the night. I think other podcast guests you've had can definitely go into the
00:43:21.220 neurobiology of this much more deeply. But a way that I like explaining this has to do with
00:43:25.660 evolution. If you think about it, when we're deeply, deeply asleep, we're kind of tuned out.
00:43:30.380 And on the prairie, when we figured, okay, it's safe to go to sleep right now,
00:43:33.700 our bodies prioritized getting that really deep sleep when we knew it was safe. And then as the
00:43:37.380 night goes on, we sleep more and more lightly, which makes sense because, hey, there could be
00:43:40.880 lions and tigers around or whatever that are going to come and eat us. So evolutionarily speaking,
00:43:45.280 it was adaptive to sleep more deeply in the first half of the night. Now, if your wife is falling
00:43:50.940 asleep on the couch and getting some of that sleep at that stage of the night and maybe getting
00:43:55.320 more interrupted aspects of that, because there's noise from the TV or whatnot, it could be
00:43:59.860 disturbing the quality of... That's the drawback.
00:44:01.040 That's the drawback.
00:44:01.860 Yeah, it makes sense.
00:44:02.960 To that effect, on the prairie, it also makes sense that evolutionarily, there's diversity in
00:44:08.180 people who are night owls and early morning larks. We needed that diversity in order to keep the
00:44:13.060 tribe safe from the threats on the prairie. Some people were staying up late. Okay, no lines. Some
00:44:17.480 people were up early. Okay, no lines. And there's nothing pathologic about being a person who's going
00:44:23.400 to be more likely to fall asleep earlier. Be a person who's more of a night owl. And it's very
00:44:27.700 hard to change that. A lot of patients want to change it.
00:44:30.940 Broadly, two to three different archetypes of that. I know there's a circadian rhythm test you
00:44:35.980 can take online that gives you a sense of it. I almost think it's so self-evident if you pay
00:44:41.440 attention to your patterns.
00:44:43.440 It is. I'm really a clinician, so I deal with what's in front of me all the time. I'm not so
00:44:49.380 concerned about these tests. I'm more concerned about what's the problem that's messing up your
00:44:53.040 life right now and how can we work around that.
00:44:55.720 Let's go back to sleep hygiene for a second. We talked about temperature. Nowadays, we have these
00:44:59.640 incredible devices that can cool our mattresses and things of that nature. Obviously, we have air
00:45:04.780 conditioning that can cool the room. Do you have a preference for one or the other? I mean,
00:45:11.380 clearly, not everybody needs to buy a mattress cooling device if they can't afford it. That
00:45:15.160 shouldn't be an impediment to sleep. Do you have a room temp set? We typically talk about the mid-60s
00:45:20.140 as an ideal room temp. Do you adhere to that?
00:45:22.140 Yes. Mid-60s is terrific. If people say, oh, this is just too cold, I say, well, what's too cold?
00:45:26.800 And often they will say, my feet. And we have wonderful solutions for that. They're called socks.
00:45:31.380 We can get really thick socks. I'm also not opposed to, you know, those tiny little heating pads you can
00:45:36.020 get, they're like this big foot and a half by a foot or something. Putting one of those in the foot of
00:45:40.320 your bed, it's gotten auto shut off. It shuts off after like an hour or something to fall asleep
00:45:45.280 with. I don't have a problem with that. There's no issue there. But yes, a cool room is definitely
00:45:50.740 key. And insert my refrain about down comforters, duvets, et cetera. Get cotton blankets, get cotton
00:45:56.860 sheets. Let's talk about light. Do we need to have it so pitch black you can't see your hand in front
00:46:02.320 of your face? Do we need to block the moonlight? How dark do we need it to be? This is a common
00:46:09.180 question. If you closed your eyes right now, you'd be able to tell that it's light in this room.
00:46:14.220 We can sense light through our closed eyelids. And many women would tell you that their eyelids seem
00:46:20.420 to get thinner as they age. So I think an eye mask is a great addition. And this is for a lot of people
00:46:26.200 with early morning awakenings. Eye mask can be a game change because they don't realize that what's
00:46:30.720 causing their early morning awakenings is a little bit of light getting into the wrong part of their eye,
00:46:35.700 indicating it's time to be awake right now. I don't know the details on what wavelength of
00:46:41.260 light that is or what necessarily the light is coming from, whether it's a light outside from
00:46:46.200 the sun or the moon or whatever it might be. But the point just is a lot of folks with early
00:46:50.300 morning awakening can really benefit from having something covering their eyes, whether it's a
00:46:55.460 sleep mask or there's like hats that go down here now. I'm a big fan of making your room dark.
00:47:01.200 I am one of those people who travels with a roll of black electrical tape because you go to a hotel
00:47:05.700 room and there's like 50,000 lights everywhere. You wouldn't just get relief from the eye mask?
00:47:10.980 I do, but I'm one of those people who rips my eye mask off in the middle of the night and I've tried
00:47:14.580 every single eye mask and it's coming off. So I like to wear it. I start with it. I try and keep it on as
00:47:21.720 much as I can. But I also, if there's egregious lights in a room, I cover them with a lot.
00:47:26.220 Meaning like you're going to cover the alarm clock and or whatever the.
00:47:28.920 Oh yeah. No, there's none of that in my room.
00:47:30.680 My trick is I unplug alarm clocks because I realize sometimes they're so complicated that
00:47:35.280 they just go off in the middle of the night and I didn't realize it. And yeah.
00:47:38.100 Oh, totally. And the microwaves are the worst. Those are the blinking time.
00:47:42.140 But you mentioned the cooling mattress stuff, which I'm intrigued by, but I also am concerned about.
00:47:48.580 It seems that a lot of these mattresses have settings where you can make it cooler,
00:47:52.480 but also you could make it warmer. And I worry about two things. One is I worry about messing
00:47:58.700 with our circadian temperature biology because you remember in the 1980s for a hot minute when
00:48:04.100 electric blankets were really popular and all of a sudden they're not. They were starting to see
00:48:08.960 associations between electric blanket use and some cancers. And at the time there was a lot of
00:48:14.580 speculation that this was related to EMF. But the great thing that time does is it gives us more
00:48:19.380 perspective. And there are some indications that actually that might've been messing with circadian
00:48:24.260 temperature. And that might've been part of the issue. We know that night shift work is
00:48:28.960 carcinogenic. Do we though? Yeah. Night shift work's been declared a carcinogenic. Well, I mean,
00:48:34.200 no disrespect to the WHO, I don't know what I believe that they say. I know that there's an
00:48:38.380 association between night shift work and cancer, but do we really know that it's causal?
00:48:43.560 I think if we go Bradford Hill on this and we look at temporality, I think that there are
00:48:49.920 age-matched case control studies where they can look at people going through different control for
00:48:57.180 history effects to see are people getting more and less cancers. It is tricky because if, for example,
00:49:01.980 you look at firefighters, they're way more likely to get cancer. They work way more.
00:49:05.360 They have way more chemical exposure. They have way more other things in the mix. But I think that
00:49:10.140 some of the more classic studies have also been done with hospital workers, also confounding effects.
00:49:15.860 How do we get around the confounding effects of the obvious dietary shifts that occur in people
00:49:20.200 when they're working under those conditions? I mean, if I think back to how I ate in residency
00:49:25.820 or how I eat after a night of poor sleep, I mean, to me, that would be more the cause. I'd put more
00:49:33.100 of that on kind of the metabolic ill health that might result. But carry on.
00:49:37.380 Yeah. I think that it's often hard for people to sleep during the day. Making that change from
00:49:42.680 going to sleeping at night to being a person who sleeps during the day, for some people,
00:49:47.120 it's not even possible. You talk to some night shift workers, they sleep very little because they
00:49:51.820 just can't sleep during the day. They're not able to flip their circadian biology. But there's a whole
00:49:58.020 history, and I know we'll probably talk about thermal stuff in a bit, but of looking at
00:50:03.000 disruptions in circadian temperature as one of the most common circadian disruptions in mental
00:50:09.900 health disorders. But going back to the cancer thing, what would be the believed mechanism of
00:50:14.360 action? I would talk to an oncologist about that, and I would probably talk to a circadian biology
00:50:20.980 person about that. But what I can just speak to is just my understanding that electric blankets are
00:50:27.100 no longer here with us and very common because there were these observed ill health effects,
00:50:32.880 whether they're due to EMF or whether they're due to messing with your body temperature at night.
00:50:37.460 But what concerns me about some of the exogenous interventions like mattresses that might heat up
00:50:43.600 is there's supposed to be a normal circadian temperature rhythm that we do during the day and
00:50:50.000 during the night. And when we start imposing things on that, some of these mattresses can
00:50:55.020 actually be set to cycle at different temperatures during the night and all of these things.
00:50:59.480 Yeah. So the one that I use, just by full disclosure, I'm an advisor to that company.
00:51:03.600 The one that I use, you change how cold it is throughout the night. So I think I run it as,
00:51:09.340 I think the settings go from zero to minus 10. Minus 10 is the absolute coldest. Zero is no
00:51:15.200 temperature change. Is that like a point scale or is that degrees?
00:51:17.420 No, it's a point scale. Yeah, yeah, yeah. Yeah. So I think I get in and I have it at
00:51:22.400 minus five and then I run it down to minus 10 and then I bring it up to minus five in the morning,
00:51:28.820 something to that effect. So I'm taking it from cold to really cold up to cold.
00:51:34.200 Right. Okay. So where my concern is just that-
00:51:37.320 You're saying people would heat themselves with these things. Yeah. But that gets to the point,
00:51:41.140 which we know we don't want to be warm. We don't want the duvet.
00:51:43.720 Right. But a lot of people get in bed and they don't like feeling cold because it is easier to
00:51:49.660 fall asleep when your hands and your feet and your skin is warmer. So people will maybe mistakenly do
00:51:54.540 this for more of the night than they should. And I'm just concerned that our circadian temperature
00:52:01.340 rhythm is an exquisitely controlled system. And a 10 point scale on a device, I think,
00:52:09.640 pales in comparison to the complexity of what our bodies need to do in terms of temperature
00:52:13.700 during the night. The good news is if you can keep your room at 65, none of this matters.
00:52:18.020 And the biggest challenge, honestly, is hotels for most people. It's where you have the hardest
00:52:21.720 time. Hotels are the worst. And there are some mattresses now, they're just hot. There's a short
00:52:26.940 list of mattresses. I just tell people like, look, that's going to be a hot mattress. Don't get that.
00:52:31.320 And you want to be really careful to make sure that you can be cool in your bed. And I think the
00:52:36.600 easiest way to do that, if you don't have the money to splurge on something that's going to be
00:52:41.060 a mattress that's going to definitely be cool, would be keeping your room cool.
00:52:45.040 What about blue light before bed? I've looked at these data quite a bit. And I would say that
00:52:52.520 six years ago, I was in the camp of every light had to be red. So I had to have my phone shifted
00:53:01.160 into a red light phase. My computer shifted into a red light phase. I had all of these apps that
00:53:05.940 managed all of this stuff. So as soon as the sun went down, blue light was being removed from my
00:53:11.960 electronics. And I have to say, I sleep subjectively and objectively better today. I say objectively,
00:53:20.480 if you can believe what a sleep tracker tells you, but we can bracket that and come back to it,
00:53:25.300 we should. Never taking blue light out of my devices, but instead paying attention to what I'm
00:53:31.780 consuming. In other words, my new hypothesis has become, it's not the blue light that is the
00:53:37.980 problem. It's the stimulus that often comes with the blue light. In other words, not looking at social
00:53:44.760 media, regardless of light color is a far greater positive impact on my sleep than looking at those
00:53:53.480 things, but just making sure that there's no blue light coming through. So let's talk about that.
00:53:58.080 What is the role of minimizing blue light when it comes to preparing for sleep?
00:54:04.160 First, I want to completely agree with you. We didn't evolve for the neural experience of Instagram.
00:54:08.960 We're not ready for that. I think regardless of what color light you're getting your Instagram on,
00:54:13.920 that's probably not helpful before you go to bed. So I think that you're entirely right. I think the
00:54:18.720 larger problem is not necessarily the blue light, but is the thing that we're interacting with,
00:54:23.800 whether it's an iPad or a phone or a computer, because typically those things are going to involve
00:54:28.680 social media, work, email, all of these other things that I think are much more potent disruptors
00:54:35.140 of sleep than the blue light itself. I must caveat this though. I have had a few patients who they were
00:54:41.560 not using Instagram before bed. They were not doing email before bed. None of this.
00:54:47.000 Not doing anything stressful or stimulating. No, but I just finished with a patient recently like
00:54:51.800 this who found that using orange colored glasses, and I'm talking orange colored glasses, not those
00:54:58.300 beautiful blue light blocking glasses that are clear lenses that I'm not sure what they're really doing
00:55:02.860 sometimes. I'm talking ugly motorcycle looking orange lenses. I found that a handful of patients
00:55:10.740 wearing these two hours before bed, it completely ameliorates their sleep onset insomnia such that
00:55:17.400 they were able to almost immediately quit Ambien. The beauty of these interventions is if you can
00:55:22.560 isolate them to one change at a time, you can be empirical about it. And something like wearing
00:55:27.640 glasses is benign. I mean, you're only out the money you spend on them. And if it works, great.
00:55:34.720 And if you really want to test it, take them off and see if your symptoms return. And if they don't,
00:55:40.200 maybe it fixed you, maybe it wasn't that. Who cares if they return and you can fix it? Yeah. Like
00:55:44.300 I try not to be terribly dogmatic about this stuff, but I also think that when people go to
00:55:50.480 great lengths to remove blue light without removing stimulus, they're missing the boat a little bit.
00:55:57.540 And for me, social media is not much of a stimulus actually, because I don't pay that much attention
00:56:01.140 to it, but work is. So for me, the single worst thing I can do right before bed is look at email.
00:56:08.560 Whereas watching TV, it's a total beautiful way for me to be distracted by watching something
00:56:14.860 mindless on Netflix for an hour. And as long as I don't go and check my email and see what got sent
00:56:21.200 to me in the last hour, it'll be great. It doesn't matter that I just finished watching a big bright
00:56:26.180 screen of Netflix. It doesn't seem to impact me. Well, one is much more interactive and stressful
00:56:31.080 and one is very passive when you're just watching a movie that has nothing to do with you,
00:56:34.180 no bearing on your life. What I would say back to your, what I'm going to call A-B testing,
00:56:39.080 whenever you want to test one of these individual, what I call low hanging fruit interventions,
00:56:43.600 you want to collect your own data on a paper sleep diary for two weeks, make the change.
00:56:48.440 You must do it for two weeks. And there's a few more low hanging fruit pieces of sleep hygiene.
00:56:53.920 By the way, do you have a nice template? We have one that we give our patients. Again,
00:56:57.100 it's super low tech. It's a piece of paper.
00:56:58.600 So low tech.
00:56:59.120 Do you have one on your UCSF website?
00:57:01.420 I can make it public. Yeah.
00:57:02.680 Yeah. Yeah. Okay. Maybe we'll link to it in the show notes.
00:57:04.660 Yeah. Easy to do.
00:57:06.020 We'd link ours as well, but yours is probably better. Ours is like boxes you color in.
00:57:10.440 Oh yeah.
00:57:10.900 And it's like you put C when you had caffeine, A when you had alcohol, E when you exercise. So
00:57:17.060 we're documenting when did you exercise? When did you have food, alcohol, caffeine, and when were
00:57:20.940 you in bed and when were you sleeping by the shading?
00:57:23.460 Yours might be even more high tech than mine, but what I will tell you is mine is just enough to get the
00:57:28.760 information that I will definitely act on and nothing else. But I will tell you, can I go over
00:57:33.460 a couple more pieces of low hanging fruit on sleep hygiene?
00:57:37.140 Yep.
00:57:37.880 Okay. So back to the glasses. If you are a person who has trouble with what we call early insomnia,
00:57:42.980 so difficulty falling asleep at the beginning of the night, and you're already not looking at your
00:57:47.520 email, not doing Instagram, you're just annoyed that you cannot fall asleep at the beginning of
00:57:52.200 the night. It's worth it to try these glasses for two hours a night for two weeks and see what
00:57:56.020 happens. It's so easy to do.
00:57:58.480 To be clear, is there a particular brand?
00:58:01.560 I have no affiliations with any of these things. I can tell you there's some really nice ugly ones
00:58:06.500 from lowbluelights.com, I think, if they're still in business. But they look like motorcycle goggles.
00:58:12.080 I do think that the wraparound feature is important because if we're going for it, let's go for it.
00:58:16.780 It's a worthy thing to do.
00:58:18.660 Another important thing to do is to talk to your physician.
00:58:22.700 I'm not a physician, but I work with a ton of them. And I learned this from an anesthesiologist.
00:58:28.640 All medications have circadian effects. All of them. Somehow, it's probably not known for all of
00:58:34.180 them how they do, but they do. Make sure you are taking your medications at the same time every day
00:58:38.940 and at the right time of day. For example, I once had a patient coming in saying they were taking
00:58:44.020 450 milligrams of bupropion for depression before bed. No. That's going to be a pretty stimulating dose
00:58:50.440 of something to take for bed. So make sure that you go over your medications with your doctor
00:58:55.000 and that you're taking them at the optimal times of day and be really consistent with your medications.
00:59:01.040 And another one that is a particularly low-hanging piece of fruit is something called
00:59:06.560 decaffeinated coffee. Turns out there are speculations that decaf coffee can have as much
00:59:12.560 as 15 to 30 percent of the caffeine that regular coffee has. I haven't found that reference.
00:59:18.180 I've dug. I've tried to find one that will show that. I haven't found exactly that.
00:59:22.860 But there are some data from 2006 that were published saying that 15-ish percent. But then
00:59:27.680 again, more recent data have shown that Starbucks, I think, says that their 12 ounce has 155 milligrams
00:59:33.600 of caffeine. But outside laboratory testing found 310, something like that. So when you're
00:59:39.920 decaffeinating coffee that's much more caffeinated than you started with, this can make an absolutely
00:59:44.600 huge difference. I tell people we're done with caffeine by 11. That's my 11 a.m. That's my
00:59:49.580 standard. Unless we've got an extreme phase delay or phase advance, I should define those terms.
00:59:54.960 A phase delay is when you go to bed really late and you wake up really late. A phase advance is
00:59:59.120 when you wake up really early and you go to bed really early. So someone who's waking up at like
01:00:03.800 3.30 in the morning and going to bed at like 8 p.m., that would be a phase advance. Phase delay would
01:00:11.560 be like, I'm going to bed at 3 a.m. and I'm waking up at 10 a.m. So in those cases, I might do something
01:00:17.160 differential with the caffeine. But for most people who are neither of those, I'll cut it off
01:00:22.020 at 11. That includes your caffeinated coffee and your decaffeinated coffee. And I never take people's
01:00:26.920 caffeine away. Caffeine withdrawal is not something I want to deal with in my clinic, and I don't think
01:00:32.000 it's necessary. You can cause a lot of damage taking away someone's coffee. People really don't like
01:00:36.980 that. It really puts them in a bad mood. And it's not necessary. So I tell people, do not change how
01:00:42.660 much coffee you're drinking. Put it all before 11. Just move it all.
01:00:47.320 What fraction of people are such rapid caffeine metabolizers that they seem immune to caffeine and
01:00:52.680 sleep?
01:00:54.000 I think that that person doesn't actually exist. I need to be convinced what the normal caffeine
01:00:59.700 half-life is four to six hours. So even if we take someone who's four hours, that means after four
01:01:06.280 hours, you still have half of a cup of coffee. And after eight hours, you still have a quarter of a
01:01:11.500 cup of coffee. And if you have that coffee at 2 p.m., and that coffee actually had 310 milligrams of
01:01:19.320 caffeine in it, and it was only a tall coffee from Starbucks, there's a lot of contingencies to build
01:01:24.360 in here. But I could tell you people, someone we both just know, actually stops using decaf coffee
01:01:32.320 after dinner. And it's a world of difference for their sleep quality. People will say, oh, no, I fall
01:01:37.340 asleep just fine. It doesn't affect me. Well, it is affecting you. It's affecting the electrical quality
01:01:42.120 of your sleep throughout the whole night. And I would refer you to talking to a sleep neurologist
01:01:47.040 to interpret some of those sleep studies and talk with you more about that. For my purposes,
01:01:53.020 all I need to know is the person who's trying to fix the insomnia is, oh, you're having two decaf
01:01:57.680 coffees after dinner every night. That could add up and that could be doing something, and that could
01:02:02.180 make your sleep less restful. Okay. Low-hanging fruit. Just stop it at 11. Stop it. Like, do the
01:02:07.640 experiment at a minimum. Okay. So those are three. But don't reduce it is the key thing. Any other
01:02:13.400 really obvious things to A-B test for two weeks? No, I think that that's the major part. I will tell
01:02:19.860 people also, people like to fall asleep with podcasts on, don't do that. Including this one, right?
01:02:26.220 Right. Yeah. This is an easy one to fall asleep to, but I don't know. I hope that people aren't
01:02:31.560 falling asleep listening to this. Although, if this helps some sleep. One other thing I want to
01:02:35.040 talk about is on the relaxation techniques, where does or does mindfulness-based practice come into
01:02:40.020 it? So anyone who's done mindfulness-based meditation probably appreciates how difficult
01:02:45.560 it is. It's not like transcendental meditation where you're focusing on a mantra. You're instead
01:02:51.800 focusing on a sensation, typically breathing. But body awareness is a thing that you want to focus
01:02:57.240 on. Is that counterproductive or is it productive as you're laying there awake?
01:03:02.180 So my unsatisfying answer to so many questions is always going to be, it depends,
01:03:05.880 because there's moderator variables. And when it comes to CBTI, what we know is that what's been
01:03:11.160 tested is progressive muscle relaxation, which you could argue is a form of a body scan, which is part of
01:03:17.140 many mindfulness practices, where you scan your whole body, you think about your hands, you notice
01:03:22.500 how they're feeling, are they warm, are they soft, whatnot, and you move through your whole body.
01:03:26.320 With progressive muscle relaxation, you squeeze your hands and you let them go. You squeeze them
01:03:30.540 and you let them go. It's more of an active process that you're paying attention to throughout
01:03:34.760 your body. Doing this in bed right before you fall asleep for a few minutes is fine. That's the one
01:03:40.320 exception to the sleep and sex rule. I tell people that it's also fine to practice this in other parts
01:03:45.320 of your house. You don't have to just be in bed. But the body scan and mindfulness in general has
01:03:50.300 been studied in combination with CBTI. And what the data have shown is somewhat fascinating. There's
01:03:57.140 no actual differential improvement on sleep duration or metrics of sleep. But people like
01:04:05.360 the mindfulness stuff. They report they're more happy with it. They like doing that. But in terms of
01:04:10.280 actual improvement on sleep outcomes, I don't think it really adds too, too much to CBTI. The effects
01:04:16.440 with CBTI are pretty whopping. When it's done well, 50 to 60% of people can get remission and 70% can get
01:04:24.280 clinically meaningful improvement to their sleep. So in the world of psychological treatments,
01:04:29.760 that's really good. But to circle back to your question, mindfulness is great. I think there's a lot
01:04:36.140 of practical uses for it for helping yourself when you're in psychological states you don't want to
01:04:41.620 be in. It's a great way to be in life. But when it comes to sleep, do I need you to start a
01:04:47.680 mindfulness practice to improve your sleep? No. So you mentioned 50 to 60% of people are going to
01:04:52.760 have a remission. Closer to 50, but yeah. 70% will have a meaningful clinical improvement. Of the 30%
01:05:00.560 that do not. Why? When does the treatment fail? The treatment fails when people don't do it.
01:05:07.100 So in other words, we're really saying 30% of people are not able to adhere to the treatment.
01:05:11.620 I wouldn't go that far. There are some people who are genetically short sleepers.
01:05:15.580 And at some point, this may become distressing for them. I had a story of a patient who was in her 70s,
01:05:22.020 came to me saying, I have a huge problem. My sleep is not good. And I asked her, okay, so tell me all
01:05:28.320 about this. She was like upper 70s, had a volunteer job, really active, full workout plan. I'm like,
01:05:36.060 you're crushing it, lady. What's the problem exactly? She says, well, I joined this study
01:05:40.520 and I had to wear this wearable device. And I woke up in the morning and it says that things are not
01:05:47.080 going well every morning, morning after morning. And it says I'm at risk for different things. I'm not
01:05:52.740 going to say which wearable company it was. And I said, oh, okay.
01:05:55.320 There's an amazing treatment for that. Can I see the wearable device?
01:05:57.920 Can I please just have that wearable device?
01:05:59.940 Here's my vice grips.
01:06:00.900 Boom. Exactly. This was a while ago, but I took it away from her and the wearable devices now are
01:06:07.200 not doing this. This was, gosh, seven, eight years ago.
01:06:10.860 I made a note to ask you this question. When do you tell people, because we do this with our patients,
01:06:16.840 which is take the tracker off. We're doing a six month tracker holiday, done with the tracker.
01:06:22.460 Done.
01:06:22.680 So is that mainstay part of your treatment is like, let's get all that anxiety out of there?
01:06:27.640 For people with insomnia, I tell them, yes. Coming to me in my clinic, the people who have
01:06:34.640 bothered to wait a year and a half to get into the clinic, those people, yes, I am telling them that.
01:06:40.460 And so to go back to your 30% of people, the genetically short sleepers who become distressed
01:06:45.120 about their sleep are not going to be helped by CBTI. They're not.
01:06:49.120 Maybe they shouldn't be helped. Maybe there's nothing to fix.
01:06:51.060 Correct. But they're presenting, so I'm putting them in the group. And then, yes, we know that
01:06:55.520 there's such a huge body of data on CBTI at this point. It's just wonderfully studied. And we know
01:07:01.540 that when people don't do the treatment, it doesn't work. Adherence is a major, major component.
01:07:06.300 Duration of treatment also matters. It seems that if you do four or more sessions with a therapist
01:07:12.300 doing the CBTI, your outcomes are going to be way better than if you try and cut it way short with one
01:07:16.420 or two. My treatment is five sessions. I do an intake, you get five treatment sessions,
01:07:20.820 and then I do a follow-up where we just tidy things up.
01:07:23.580 And the space between them is a week?
01:07:25.300 Always one week. I am militant about this. If you're going to miss a week, you can't be in it.
01:07:30.220 You have to wait for the next cycle.
01:07:32.160 Given that people are waiting a year and a half to see you,
01:07:35.400 tells me that there's a mismatch on the supply-demand curve.
01:07:39.360 Yeah.
01:07:39.420 Why is that the case?
01:07:41.420 First of all, there is a great directory. Can I give you for the show notes?
01:07:44.620 Yes.
01:07:45.140 So there's actually a way you can look up-
01:07:47.220 We use it ourselves.
01:07:48.580 The Society of Behavioral Sleep Medicine thing?
01:07:50.280 Yeah.
01:07:50.300 Yeah.
01:07:50.840 So that is how you would find a provider who definitely knows how to do CBTI.
01:07:55.460 One of the major problems comes down to psychologists and providers taking insurance. A lot of the
01:08:02.940 best folks there in private practice, they don't take insurance. And you could be paying hundreds of
01:08:08.160 dollars a session to see them. And they're pretty backed up as it is, and they don't take insurance.
01:08:13.600 I am fortunate. I get to work at UCSF at the Osher Center for Integrative Health, and
01:08:17.600 we take Medicare and all kinds of insurance so people can pay minimal or non-existent co-pays
01:08:24.260 to see me. And there are other CBTI providers at UCSF. Their wait lists are long, long, long too.
01:08:31.880 In fact, in order to see patients now with any volume, I don't see individual patients. I see
01:08:37.820 eight patients at a time in group medical visits. And I do it 90 minutes every week,
01:08:42.420 all eight patients in that 90 minutes to get it done.
01:08:46.720 So what will it take for AI to replicate what you're doing to scale this much more? Because
01:08:53.020 a lot of this, a lot of the work I do can be done by an AI. How much of the art and science of this
01:09:01.780 is teachable to LLMs, and at least as another offering? I'm not saying it should ever displace
01:09:07.580 what you're doing or what a therapist is doing. But if we have a backlog of people for years,
01:09:14.280 shouldn't we have an alternative which might say, look, there's an online course that you can do that
01:09:18.960 will give you 70% of the value of what you might get sitting in the group with Ashley?
01:09:24.340 Hey, if you can find a way to replace me, I'm here for it.
01:09:27.440 Or just come up with an alternative to scale.
01:09:30.040 Here's the issue. There are some CBT apps, smartphone apps, interventions out there.
01:09:35.740 And I've had patients who've tried these while they're waiting.
01:09:38.840 Yes, exactly.
01:09:39.580 And they'll come in and they'll say, oh, it might have helped a little bit.
01:09:43.440 And I think the major issue is that many, many people with sleep problems think that their sleep
01:09:47.740 problem is unique. It's special. This can't be treated by just a generic app.
01:09:53.100 My problem is different. And the joy of me having a group is that people can hear that
01:09:58.340 everybody's problems are different. And I'm going to treat you all the same way.
01:10:01.700 Y'all are going to do the same things. You might do it at different times,
01:10:03.760 but you're all going to do the same things. And I think that there is a world where AI can
01:10:09.800 help with the personalization aspect. I'm actually helping a company that's making an app. It's called
01:10:16.000 Rest. And they are integrating AI to use, for example, the way that I calculate someone's wake
01:10:23.100 time, which is not something that's in standard CBTI. They're incorporating that and they're able
01:10:28.940 to actually do more tailoring. And I'm excited to see where it goes. But I think that the biggest
01:10:33.220 fly in the ointment with this is going to be getting patients to look at the fact that they
01:10:37.240 have been assigned to wake up at the same time every day for the next seven days and think,
01:10:41.500 oh gosh, I only wake up at 5 a.m. two days a week. Normally now I have to do it every day.
01:10:46.940 Getting them to really do it is going to be hard. Before my patients enroll in my clinic,
01:10:51.400 they watch a 10-minute video. And it's a really scary video. In that video, I'm basically saying,
01:10:56.260 look, this is going to be hard. You're going to hate me. You're going to want to make a dartboard
01:10:59.680 with my face on it and play darts on it. You are going to suffer in the beginning of this treatment.
01:11:04.860 But guess what? You have been suffering for months or years. Now you're going to suffer for
01:11:11.260 five weeks. You're going to do it my way. And if you don't like it, you can go back to your way.
01:11:15.000 This is five weeks of your life. How bad can it be? How much worse can it get?
01:11:19.140 So I do one of these kind of pep talk videos. There's just something about knowing that someone
01:11:25.060 else is actually really paying attention to one of the biggest problem, if not the biggest problem
01:11:30.700 in your life at that moment. Sleep is a 24-hour-a-day problem. This is not just a problem at night.
01:11:35.680 It is affecting you all day. It is intensely personal. So it's a lot to trust an algorithm
01:11:42.420 or an app to know, oh, okay, I really should do these things. I think it's a big ask and it's hard.
01:11:49.600 By the way, when you're giving them that bootcamp speech, is the time in bed restriction typically
01:11:54.540 the thing that causes the most distress?
01:11:56.500 They don't know about that at that stage. People are in the dark at that stage. I just say,
01:12:00.040 look, we're going to do this thing. It's going to be really hard. You're going to get worse before
01:12:03.500 you get better because everybody sleeps less the first couple of weeks while we're getting
01:12:06.820 all these things lined up. And for some people, what ends up being the hardest is the wake time
01:12:13.380 because they're used to just sleeping in whenever they can or catching up on those hours when they
01:12:18.520 can. For other people, the super late bedtime that I give them, that's what crushes them.
01:12:24.840 They're like, oh my gosh, I have to stay up until then. But the great news is that we dial it back
01:12:29.420 over time. And I don't think we talked about this part with time in bed restriction,
01:12:32.180 which is just that there's a benchmark for efficiency, sleep efficiency. And we define
01:12:37.400 sleep efficiency as the amount of time that you're in bed sleeping divided by the entire
01:12:42.160 time that you're spending in bed. And the benchmark is 85%. So each week I'm actually calculating sleep
01:12:47.740 efficiency from people's paper sleep diaries. And once we do time in bed restriction, if they are
01:12:52.540 above 85%, I move their bedtime back 15 minutes. And then if that's the same for another week,
01:12:58.820 you move back another 15 minutes. And people say, 15 minutes, what? Who cares? I'm like, oh,
01:13:03.700 you'll care. After four weeks, that's an extra hour every night. That's huge.
01:13:09.180 And are people able to, with a high enough fidelity, report awake time in bed? For example,
01:13:16.100 like if I were doing this, let's assume I've got a clock next to my bed that I can look at,
01:13:20.200 because you have to do that for this purpose. You have to have some device to keep track of time.
01:13:24.460 So I get in bed because my time in bed tonight is 11 and my wake up time tomorrow is 530. Okay. So I
01:13:31.700 get in bed. It's 11. Check. Okay. How do I know what time I fell asleep? Let's just say I didn't
01:13:36.800 have an issue falling asleep. How do I know if it's 1115 versus 1130? I'm looking for the difference
01:13:42.580 between five minutes and 50 minutes for that time to fall asleep thing, right? And in the middle of
01:13:47.280 the night when you're waking up, guess what? If you're not getting laid, you're getting out of bed.
01:13:50.660 So you can look at the clock and be like, all right, I'm out of bed. And then you have to go do
01:13:54.100 what I call a very fun and potentially embarrassing activity. Embarrassing meaning if your boss caught
01:14:01.960 you doing this activity during the workday, you should feel embarrassed. So for example,
01:14:07.180 reading People magazine or reading some trashy magazine, you wouldn't want to be caught at your
01:14:11.220 desk doing that at work. That's exactly what you should be doing in the middle of the night.
01:14:14.840 So person wakes up at two in the morning and they can't go back to sleep. Get up,
01:14:19.360 go and do something that is not productive, not rewarding in the way that, hey, this is,
01:14:26.720 I'm building a pattern around getting up and doing something I like. So I wouldn't be able
01:14:30.620 to get up and play chess. I wouldn't be able to do the online chess thing that I love.
01:14:34.900 Maybe, maybe not. I mean, I tell people they can play solitaire. Adult coloring books are all the
01:14:39.200 rage. I couldn't check email. No. Work-related work is a definite no.
01:14:43.740 What about scrolling social media? No, no. We don't like that. Although that meets the criteria
01:14:49.120 of you wouldn't want your boss catching you doing it. We don't do social media or interactive.
01:14:53.900 Read for pleasure? That's fine. Okay.
01:14:56.340 But we don't read about global warming, current events, politics, pandemics. Those things are
01:15:02.120 off the menu. Stock trading?
01:15:03.920 Ooh, not if it's stressful. I wouldn't do that.
01:15:06.800 Okay. So there's a narrow subset of activities that you are going to get out of bed to do.
01:15:10.780 Yeah. Stuff that's kind of boring, but entertaining enough. Because we don't want you to get a habit
01:15:16.740 of looking forward to doing something in the middle of the night. This happens with parents.
01:15:19.940 Like a parent, for example, who might be busy all the darn day with their kids and their family's
01:15:25.040 needs and everything else. Then in the middle of the night, they wake up and it's like, oh,
01:15:28.580 this is me time. This is when I'm going to do all these really fun things that I don't get to do
01:15:33.380 during the day. We don't want to make a habit of you time being between 3 and 4 a.m. That's really
01:15:38.600 when you want you to be sleeping. Sometimes you have to schedule that stuff during the day,
01:15:42.580 but we want the stuff in the middle of the night to be mildly boring. And to that end,
01:15:44.920 back to your blue light thing. I don't mind if people watch, for example, an episode of MASH
01:15:49.560 or Gilligan's Island or Sex and the City or some other sitcom. I like 20-minute episodes because
01:15:54.860 then you can generally turn it off, check in with your body, think, am I ready to go back to sleep?
01:15:58.860 And then you can go back to sleep. Do you remember in the 90s, if you played video games ever,
01:16:03.440 how we had those cartridges and we'd put them in. And sometimes we have to take them out and
01:16:07.760 blow them out to put them back in and reset them because they would freeze. That's what you're doing.
01:16:12.960 When you get out of bed in the middle of the night, you do a different activity,
01:16:15.880 you're resetting and then you're going back to sleep instead of just having stewed in bed that
01:16:20.400 whole time. And it's much easier to fall back to sleep when you have that reset.
01:16:24.300 So we don't want the activity to be too stimulating, but just mildly boring and entertaining enough.
01:16:30.560 Does that track?
01:16:31.340 Yep. One obvious thing we haven't talked about, and maybe it's so obvious we don't need to,
01:16:35.180 but just to close the loop on it is food and alcohol and how they pertain to this.
01:16:39.800 What's the checklist you run through with the clients?
01:16:41.580 So since we're dealing with so much life, I actually don't mess with their food. All I do
01:16:46.820 is say, hey, really, let's try to not eat within three hours of going to bed. Sometimes it's rare
01:16:51.500 that I'll have nighttime binge eating disorder to deal with at the same time or a blood glucose issue
01:16:56.820 that in diabetes that's poorly controlled at the same time. But I'm going to put those cases aside
01:17:00.860 for just a moment. So I generally will go with don't eat for three hours before bed. And when it comes
01:17:06.180 to alcohol, I tell my patients, look, this is five weeks of your life. I'm not going to drink
01:17:10.640 and you're not going to drink. So when I'm running a clinic, nobody's drinking. And the reason for
01:17:15.280 this is that in order for me to actually see what's going on with your sleep, I need to see
01:17:19.480 this with the least perturbation possible. Alcohol and marijuana are those things. Now,
01:17:24.660 if people are using a lot of marijuana or a lot of alcohol, I'm not here to put people into withdrawal.
01:17:29.700 So they just don't enroll until they're...
01:17:32.220 No, no, no. I'll let them in. So what I'll do is before people come to their first group,
01:17:36.160 I have them do a sleep diary so I can see what's going on. And before that, I will have done their
01:17:40.460 intake and I'll have them have told me their alcohol intake. And I'll have decided, all right,
01:17:44.000 here's what you're going to do. You're either going to not, or I just finished with some people.
01:17:48.120 One of them was drinking between 16 and 20 ounces of wine a night. It's huge. And I said, okay,
01:17:53.740 so you're going to drink two ounces of wine a night out of that same glass. And then, you know,
01:18:00.040 you're going to keep using that glass and you're going to drink something else, some other frou
01:18:03.220 frou drink. I don't care what it is, but I want it to be something that you don't drink during the
01:18:07.020 day. So I want it to be overpriced juice or overpriced bubbly water or something like this.
01:18:11.760 Something special.
01:18:12.240 Something special. And you're going to keep drinking it out of that wine glass. And I have them do that.
01:18:16.620 And I make sure they can do it before they start treatment. And they generally can,
01:18:20.120 because again, the other part that I have going for me is that people have been waiting so long
01:18:24.560 that by the time they get to me, they'll do what I say, which is just this lovely gift that I have.
01:18:31.020 But I'll make people be very consistent with that. They'll be like, oh, I have to drink two ounces
01:18:35.600 of wine a night. I'll say, yes, you do. You must. I want this consistent. That's the thing,
01:18:40.220 consistency. So if someone's saying, oh no, I drink three nights a week. And I'll say, all right,
01:18:44.320 cut it out. You're going to stop. I'm going to stop. We're all going to stop.
01:18:46.760 Are there any specific cognitive techniques that people are instructed to be working on
01:18:53.160 when they first wake up? No, nothing. There's nothing, no mind game to play. It's all behavior,
01:19:01.380 behavior, behavior. I'm all business. Yep. At CBT, I'm a purist and I don't involve the cognitive
01:19:06.720 techniques until week three of five with treatment. And that's when we get into things like scheduled
01:19:12.340 worry time, working with the thought records. And then also one of my favorite things to do with
01:19:18.800 patients who seem to wake up in the middle of the night, maybe at 1 a.m. they jolt themselves awake,
01:19:24.080 worrying about something in particular. I have a patient like that who every night in the middle
01:19:29.200 of the night wakes up at 1 a.m. and says, I'm very worried about thing A. I'll say, okay, thing A.
01:19:35.780 Here's what I'd like you to do with thing A. I would like you to track how worried you are about
01:19:41.320 thing A all day, every couple of hours. This is called tracking degree of belief in a thought.
01:19:47.620 And what you might find is that I'll build on this with an example of a patient that I had,
01:19:51.860 actually. This might be an easier way to explain it. I once had a patient with multiple sclerosis,
01:19:56.340 early 30s, pretty debilitating disease to have when you're that young, working a full-time job,
01:20:00.820 who used to jolt awake in the morning, every morning at 7 a.m., thinking, I'm never going
01:20:05.220 to make it through this day. My whole body hurts. This is a mess. I'm never going to be able to do
01:20:08.760 this. And she would lay in bed for two hours until like nine o'clock, thinking these thoughts,
01:20:13.200 just, oh, I can't do this. By nine o'clock, she'd get out of bed. She'd shower. She'd get to work by
01:20:18.000 10 o'clock because in the Bay Area, all these startups don't start till like 10. She'd get her coffee,
01:20:23.380 work with her assistant, do her meetings. And if I asked her, how much do you believe that thought,
01:20:27.460 I'm never going to make it through this day at noon? She'd probably say, oh, like 60%. Like
01:20:33.020 this afternoon is going to be rough. I don't know if I'm going to make it through. But if you ask her
01:20:36.160 at 5.30 when she's done working or whatnot, oh, how much do you believe that thought, I'm never
01:20:41.580 going to make it through this day? She'd be like, oh, I made it 0%. Day after day, she started realizing
01:20:46.260 like, oh, I don't believe this thought at 7 a.m. because it's true that I'm never going to make it
01:20:51.560 through this day. I believe this thought because it's 7 a.m. Once she was able to make that connection,
01:20:56.560 we were able to recapture her mornings. And at 7 a.m. she went and sat on her couch and she started
01:21:00.860 doing something she loved between 7 and 9, which for her was learning Italian with an app. She loved
01:21:06.560 it. And 7 to 9 used to be her most hated part of the day. But by the end of treatment, it was her
01:21:12.580 most beloved part of the day because no one was bothering her and she could learn Italian and
01:21:16.000 whatnot. And so one of the cognitive tools that I've built into CBTI in that cognitive package is
01:21:21.980 tracking how much you believe a thought over a given day. And if you believe a thought in different
01:21:27.840 levels throughout the day, how true can it really be? And it's really enlightening. And I would invite
01:21:33.040 you to notice what you're thinking about at 1 a.m. and then just see how worried are you or how much
01:21:37.100 do you believe this the next day at 3 p.m.? Oh, not at all. How come this deserves airtime at 1 a.m.
01:21:42.980 but not 3 p.m.? Let's talk about sleep supplements. So do you do a purge of supplements when people
01:21:52.260 come to you and they say, hey, I'm taking a pound of melatonin every night. I'm on an ashwagandha
01:21:58.740 drip. Just rattle them off. We could go through the list. Can I give you two links for the show notes
01:22:05.040 to studies of melatonin supplements that found that these melatonin supplements either had none of what
01:22:10.920 they said they had in them? Yes. I think we wrote a newsletter on one of them. Oh, great. Well,
01:22:14.500 there's been two. And when people come in and they say they're taking melatonin, I'm like, okay,
01:22:18.840 the alleged melatonin, how much of this are you taking? Let's assume that they're taking melatonin
01:22:23.000 because they're getting it from one of the companies that submits to third-party testing.
01:22:27.060 And so now they know they're doing it. And again, let's further posit that they're not taking a dose that
01:22:34.700 is deemed too high. So if you look at some of the sleep literature, there seems to be most people would
01:22:40.340 agree anything north of a milligram is probably just too much. Whereas kind of in the three to
01:22:46.040 600 microgram, there might be some benefit and more importantly, not just benefit, but actually
01:22:50.860 safety. You're not down-regulating melatonin receptors. You're offsetting the natural decline
01:22:56.460 in melatonin levels over time. I can tell from your face, you don't agree with any of this.
01:23:00.700 It's puzzling. So my face is also because it's hard to know where to go with this question because
01:23:04.300 some countries you need a prescription for melatonin. This is something prescribed by a doctor. It is
01:23:09.380 regulated. I don't remember all the countries off the top of my head, like Australia, New Zealand,
01:23:13.340 whatnot. You want that? You're not going to find it at their Walgreens. But in the U.S.,
01:23:17.040 taking too much can't kill you. So here you go. By the time someone gets to me, if they've got a huge
01:23:20.740 list of supplements and they still have a sleep problem, I say, okay, so clearly these aren't
01:23:24.500 doing what you want. They might be undermining what we want to do. I don't know what's actually in all
01:23:30.320 of those things because none of that's regulated. The data for things like ashwagandha are weak.
01:23:35.300 If you want to go Bradford Hill, we could. The data are also pretty weak for melatonin,
01:23:41.040 except in certain cases, which we can unpack a few of those with the explicit acknowledgement
01:23:46.800 that I'm not a physician. I've not been trained in the biological substrates, whatnot. But your
01:23:51.440 question is, do I take people off of this stuff? Yes. Get off that stuff. If you want to take it
01:23:55.920 after treatment with me again, great. But let's get off of it for now and let's see what your body's
01:24:00.540 actually doing. Because chances are you've been adding a supplement or two or whatnot over time
01:24:05.160 for years, and we don't even know what your body wants to do now. And you actually could be shooting
01:24:08.440 yourself in the foot with some of these things. Now, on the contrary, sometimes a patient will come
01:24:13.120 in and will say, oh, I'm taking a beta blocker for blood pressure. Now, you and I both know that's
01:24:16.780 like a fourth or fifth line treatment for blood pressure at this point. Nevertheless, beta blockers
01:24:21.800 inhibit melatonin secretion. And yet most prescribing doctors who are giving out beta blockers don't
01:24:27.900 realize that there's a significant risk of insomnia when you prescribe these to patients.
01:24:32.240 And I've had some patients who don't need treatment with me at all. They need a 0.5 milligram melatonin
01:24:39.020 pill every night, and that's it. And those are some of the most angry and satisfied patients ever.
01:24:45.240 They have one visit with me. It's done. They're furious that they've been suffering for 5, 10. I had one
01:24:50.480 patient who suffered for 30 years taking, oh gosh, metoprolol. He couldn't change his supplement
01:24:56.660 because something having to do with the vocal cords. He was a singer. Some of the other blood
01:25:00.440 pressure medications affect that. I didn't fully understand, but he would not change his blood
01:25:04.720 pressure med. So that was all that he needed. But do I think that the average healthy adult should be
01:25:10.700 taking melatonin? No, no. Now, there's probably some excellent data that you are much more aware of
01:25:17.080 than I am about how our melatonin secretion inhibition processes, whatnot, change as we age.
01:25:25.300 There may be some patients who benefit from taking melatonin, which is a hormone to induce sleep. But
01:25:31.040 remember, melatonin is like the guy at the start of the race. He's the guy with the gun. He fires the
01:25:36.260 gun. He doesn't have a car in the race. He's not helping you stay asleep. He's telling you when to
01:25:41.140 start the thing. So for a lot of adults, taking melatonin is really messing them up because they're
01:25:47.080 trying to go to sleep when their body isn't ready to go to sleep. They're forcing it to go to sleep.
01:25:50.460 Then they wake up in the middle of the night and they wonder why. And it's because, oh, you went to
01:25:53.960 sleep at the wrong time and your body's all kinds of confused. Yeah, interesting. So I really try and
01:25:58.600 take people off of these things so I can see what's really going on. And then if there's something
01:26:03.320 going on that looks like it might necessitate melatonin, I tag in one of my physician friends and talk
01:26:08.740 about it. So what about sleep medications? And let's talk about as many as you want. We can talk
01:26:16.460 about benzos. We can talk about trazodone. We can talk about Ambien. We can talk about the erexin-based
01:26:21.200 drugs. How many of the patients who come to see you are regularly taking one of these prescription-based
01:26:28.560 drugs for sleep? So a lot of people take over-the-counter drugs and prescription drugs for
01:26:35.420 sleep. And there was a huge shift that I noticed when COVID started. And there was a ban on flying
01:26:43.680 to different countries, Mexico and Europe. And it turns out there are a lot of people who will fly
01:26:48.880 to Mexico to get their Ambien and fly to Europe to get various sleep drugs that you can't necessarily
01:26:54.640 get here. All of a sudden, I saw a wave of patients dealing with withdrawal in the early months of the
01:27:01.260 pandemic because they couldn't go get more of their drugs. Oh my gosh, I'm screwed. What am I doing now?
01:27:05.160 How do I cope with this?
01:27:06.520 Why couldn't they get them here in that situation?
01:27:08.820 Ambien's prescription only.
01:27:10.220 They couldn't get a prescription while they were here?
01:27:12.140 Yes, because they were taking so much that they were well beyond what they could convince someone
01:27:17.780 to prescribe them. A lot of my patients are physicians. And a lot of physicians are pretty
01:27:22.820 reticent to go above FDA-recommended doses when it comes to Ambien. A lot of people don't realize
01:27:28.880 that I believe, I believe this is the case, Ambien is still the only drug that is differentially
01:27:34.420 prescribed to men and women. According to the FDA, the starting dose for women should be five
01:27:38.800 milligrams. Starting dose for men is five to ten for instant release. And then for extended release,
01:27:43.600 I believe, for women, it's 6.25. And then for men, it's 6.25 all the way to 12.5 because women
01:27:48.600 metabolize it less efficiently. So the people who I've seen, I've seen people taking 30 milligrams,
01:27:53.880 big doses. And gosh, this is a very loaded question. But there's a lot of patients who come
01:27:58.460 to me who will say, I've read something in the news. It turns out this medication I'm taking for
01:28:03.300 my sleep is bad for my brain. They're like, oh, you saw that, huh? And I want to quit immediately.
01:28:07.920 I need to quit by next week. Oh, okay. And you've been taking it for how long? Oh, 20 years. Okay,
01:28:13.560 right. So that never works. That never works. I wouldn't say that I have any sort of extreme
01:28:19.380 expertise in the different classes of sleep meds. But what I can tell you is the ones that people
01:28:24.460 most often are coming to me saying, I want to quit this. I hate being dependent on this. What
01:28:29.620 do I do? These are going to be the benzos, which doctors are becoming less and less hip to prescribing
01:28:34.840 for sleep. Ambien, the Sonata-Lanesta stuff. And then over-the-counter stuff like Benadryl,
01:28:42.120 maybe your occasional Doxepin. And then people are often prescribed Remeron for sleep and they run
01:28:47.640 into metabolic issues and they need to get off of it. So I think that covers the broadest swaths
01:28:53.680 that I see of things people wanting to quit. Now, the QVIC, it's some of these newer ones.
01:28:57.580 I don't see them as much yet. I'm sure it's coming. And what about Trazodone?
01:29:01.660 Trazodone is the one that I'm the least concerned about for a couple of reasons. I've not seen
01:29:06.800 compelling data that it negatively impacts the electrical quality of your sleep.
01:29:11.300 No. In fact, I've seen data that it does the opposite, that it's slightly positive.
01:29:14.780 Great. I'm looking for what's negative. I don't know if the study that you're speaking
01:29:18.940 of was statistically powered, if the primary outcome was improvements in sleep or decrements
01:29:24.260 in sleep. Now I'm trying to remember something that I wrote probably three years ago. I believe
01:29:29.640 the study looked at sleep duration as the primary outcome and a secondary outcome may have been
01:29:35.140 staging. Yeah. So I don't think it was powered for that, but I think they incidentally did find
01:29:39.100 an improvement. I think you've talked about extensively, like it's important to think about what was
01:29:42.840 a steady power to look at and all that. But I'm not the most worried about that also because
01:29:46.840 it's an antidepressant drug. And if someone's taking it and it is helping with their depression
01:29:52.720 and I take them off of it in the name of trying to help with their sleep, I have created a different
01:29:58.200 problem. Although the dose people take it, it tends to not have that effect. I mean, most people are
01:30:03.920 typically taking it at 25, 50, typically no more than a hundred, maybe at a hundred, depending on the
01:30:10.100 size of an individual. They're getting some of that benefit. I often see a hundred for sleep.
01:30:13.660 Yeah. And so for me, I'm thinking, Ooh, I don't know if that's just for sleep. And then I'm also,
01:30:18.180 if I see 50 even, and then I see another antidepressant, I think, Ooh, these could be
01:30:21.580 working together. You actually also have a diagnosis of depression. We need to think about
01:30:25.380 this carefully. If folks are showing up on 20 milligrams of Valium or Xanax or pick your favorite
01:30:33.020 benzo, do you have them go and do a taper detox with their physician before they come into the
01:30:40.020 CBTI program? No, I have them do it with me. So you will manage the medical withdrawal on that?
01:30:47.020 Let me explain exactly what I do. Scope of practice. So first of all, I always work with
01:30:51.760 the prescribing physician. I never start without making sure the prescribing physician is explicitly
01:30:56.980 aware of what I want to do. I talk with them. And this has to be one of your colleagues at UCSF
01:31:01.860 or whoever they're prescribing physician is. It's whoever is prescribing the medication to
01:31:04.880 this person. We now share a patient and have an obligation to. Every single time I have done this,
01:31:10.440 the physician has been in support of getting their patient off of benzos, except for one time,
01:31:16.580 which isn't even worth really getting into. But the point is, it's an overwhelming amount of support.
01:31:20.960 Yeah, I can imagine. Most of the time, these physicians have already tried to get their
01:31:24.280 patients to quit and to reduce. But in my opinion, they've tried to do it way, way, way too quickly.
01:31:31.860 And that's because there are physiological dependencies on these drugs and psychological
01:31:37.800 dependencies on these drugs. And we have to attend to both of them while we're doing this
01:31:42.520 taper process, or it's going to be a botch and the patient's going to relapse and we're going to be
01:31:46.920 back at square one or square negative one, unfortunately. So here's what I do. Let's take
01:31:53.040 a boring example. Pick your favorite benzo, favorite dose.
01:31:57.080 I don't particularly like them myself, but let's take Valium.
01:31:59.880 Valium, okay.
01:32:00.360 Long acting.
01:32:01.020 10 milligram?
01:32:01.660 Yeah, sure.
01:32:02.400 So let's say we've got a patient on Valium. They've tried to quit. They've occasionally abused.
01:32:07.420 They've gone up. They've split an extra in half. They've gone up to 15 sometimes, whatnot.
01:32:11.520 The first thing that I do with a patient is I say, all right, actually, for sake of better
01:32:15.860 example for sleep, can we do Ambien because it's a little more fun?
01:32:19.220 10 of Ambien.
01:32:20.240 Let's say 10 of Ambien every night at the beginning of the night. And then let's say sometimes they're
01:32:23.440 actually taking a fiver in the middle of the night when they wake up because they want
01:32:26.960 to get back to sleep.
01:32:28.000 I like the party dose.
01:32:29.080 Right. So let's say some nights it's 15, some nights it's 10. What do we do? So the first
01:32:33.940 thing I do is I take out the middle of the night dosing and I say, we're done with that.
01:32:37.200 You're limited to 10 a night and you got to take it before bed.
01:32:40.100 Yes. You have to take it before bed. You have to take it the same time every night. But if
01:32:42.960 you're going 15, five nights a week and 10, two nights a week, I'm going to make it a
01:32:46.280 12.5 before bed. Let's be generous. Start higher. So we'll agree on a dose that the
01:32:51.300 patient will take and it agreed upon time. So the prescriber and I agree on this. We're
01:32:54.360 like, okay, same page. This is what the patient's going to do. And they start doing that. Generally
01:32:58.240 the patient's like, no, no, no, I'm trying to quit. I don't want to take more. And I
01:33:01.080 say, no, no, before you quit, it must be stable. You cannot quit from a point of instability.
01:33:06.320 It will not work. I've seen people try and people say, oh, I want to quit. I want to go
01:33:11.080 from 10 to five. No, that's not how we roll. So let's say this patient's taking 12 and a
01:33:16.020 half and they're like, okay, I want to cut down. I'm like, all right. Okay. So how does going
01:33:20.420 from 12 and a half to five sound? And they say, oh my gosh, that's going to be really
01:33:24.180 scary. I don't think I can handle that. And what I actually have them do is I rate it on
01:33:28.080 a scale from one to 10 with 10 being the most anxiety provoking upsetting thing. And one
01:33:34.480 being not upsetting at all. This is called a subjective units of distress scale, suds, have
01:33:39.920 them suds it. So I say, okay, going from 12.5 to five, that sounds really terrifying now
01:33:45.020 because they've just done a week where they're consistent with 12.5 at the beginning of the
01:33:48.800 night. They've had no middle of the night crutch and they're not feeling great about that.
01:33:52.280 So then I say, okay, so how about going from 12 to 10? And they say, oh, not as bad, but
01:33:57.700 that's still like a six on my scale. And I do this process all the way until I get them
01:34:01.780 to a one. And I'll say, all right, so next week we're going from 12.5 to 12.
01:34:07.620 How are you even making that increment?
01:34:10.300 I can tell you exactly how we're doing that. We're going on the internet and we are buying
01:34:14.000 something called a gem scale. Now you and I both know that people who are wealthy enough
01:34:17.320 to have gems worth measuring aren't measuring their own. So the people who are buying those
01:34:20.760 scales are using them for other things. And so what my patients end up doing is they buy
01:34:24.440 these scales and they get a full-blown breaking bad setup in their bathroom. Like we're cutting
01:34:28.600 pills, we're weighing pills, we're doing math because the pill actually weighs more than
01:34:31.980 12 and a half because it's got binders and fillers. What percent do we need? And we kind
01:34:35.440 of make it fun. And they end up having to put the crumbly pill into a shot glass with some
01:34:39.580 water. We shoot it and the whole thing. We make a whole production out of it. But the point
01:34:42.760 just is. They're going from 12.5 to 12. And we do that for like three weeks. If they've
01:34:47.320 been on it for years, we're looking at three weeks. And the first couple of nights are
01:34:50.320 a little rough. There's a little stress.
01:34:51.840 If they're only doing a seven-week program with you...
01:34:54.560 Oh, no, no. This taper program we make and it will last a long time.
01:34:57.300 Before they enter the program.
01:34:59.420 No.
01:34:59.540 This is a separate issue.
01:35:00.320 This is a separate issue. And we do this after they've finished CBTI treatment. During CBTI
01:35:03.700 treatment, I stabilize them on their meds. And we just get it so they're not erratically
01:35:07.440 taking five different cocktails of things. When people come in to see me for treatment,
01:35:11.880 they'll say, oh, yeah. So Mondays, I do Ambien. Tuesdays, I do Trazodone. Wednesdays,
01:35:16.060 it's Benadryl. Because they have it in their head.
01:35:18.360 Why?
01:35:18.680 Because they think they don't want to get dependent on one. So they think that by doing
01:35:22.260 a rotating merry-go-round of these things that it's...
01:35:25.260 That's actually smart. I would have never even thought of that.
01:35:27.920 Oh, yeah.
01:35:28.760 Sinister.
01:35:29.380 It's working great.
01:35:30.140 Yeah.
01:35:30.480 So I generally work with the doctor and we decide, okay, here's the one you're going
01:35:33.260 to do. Here's the dose you're going to do. And you're going to be consistent
01:35:35.760 with this.
01:35:36.160 So vodka on Monday and then tequila on Tuesday, red wine on Wednesday, and then Chardonnay
01:35:44.180 Thursday. And this way, I'll never become an alcoholic.
01:35:46.480 Oh, figured it out, Peter. In short, I have people really stabilized during CBT. And sometimes
01:35:51.440 during week four, week three, four, they're ready to start this. And we start them on this
01:35:55.400 program. And once I have them in this way, they're able to do this on their own. So they'll
01:35:59.980 go from 12 to 12.5 for like three weeks and they'll be keeping sleep diaries. So they'll
01:36:03.720 see, oh, okay. And we'll get some confidence. And then they'll email me, you know, they'll
01:36:08.280 message me and they'll say, okay, so now what? And I'll say, all right, well, how are you
01:36:11.320 feeling? Like, what if we go down to 11.5? How does that sound? Sometimes that'll be too
01:36:15.400 scary. For some reason, crossing the five threshold is really scary. So we go from five
01:36:19.360 to 4.75 sometimes.
01:36:21.200 And just to be clear, this is psychological. There can't possibly be a physiologic difference
01:36:27.260 between four, 4.75 and five milligrams of Ambien. In fact, the medicine isn't even
01:36:32.600 homogeneously enough compounded within the capsule. So as long as everybody understands
01:36:38.400 that.
01:36:38.800 Probably not. But think some for tablets and I don't know about the requirements.
01:36:41.440 Yeah. Cause the binder and the active ingredient.
01:36:43.620 Yeah. And generic has to be 85% similar to the real deal. So there's all kinds of mess ups
01:36:47.620 here. Remember how I said there's a psychological part and the physiological part. This is a psychological
01:36:51.400 part that I think it's left out of a lot of the, oh, just cut it in half to start
01:36:55.760 decreasing your dose aspect, which is dealing with, okay, what can we physiologically do?
01:37:00.220 I'm talking about what can we psychologically do?
01:37:02.520 And do you think that this methodology of the incredibly slow taper with incredibly high
01:37:09.060 precision, do you think it works for opioids?
01:37:11.780 So I don't think I've ever seen that in my clinic. It's just not something I've had to
01:37:19.460 deal with.
01:37:19.740 Oh, I don't mean for sleep. I just mean in general. Or is the problem so grave that you have to be
01:37:24.720 a little more aggressive and switch them to a completely different class of drugs?
01:37:28.780 That's so far outside my area.
01:37:30.280 Okay, got it.
01:37:30.880 I can't speak to it. But what I can tell you is just that doing this method with the sleep
01:37:36.880 drugs slowly over time, people get more confidence and they can make larger reductions at a time.
01:37:42.360 And then importantly, Peter, when someone is tapering and something crazy in their life
01:37:46.420 happens, like a child gets diagnosed with cancer or something terrible happens, we stop the
01:37:51.820 taper and we stay where we're at. So your taper might look like this, but there's not a huge rush
01:37:57.440 to get off this thing. You've been on it for 20 years. Better to stably get off it. I always joke
01:38:01.980 with people like if you can lose 10 pounds in two days, how quickly do you think you can gain two
01:38:05.400 pounds? So when it comes to quitting these meds, slow and steady wins the race. Having people gain
01:38:10.360 the confidence that they can do it is such a big part of it. I know that one of the critiques I've
01:38:14.840 gotten from folks is like, well, wait a minute, some of these pills have coatings and da, da, da, da,
01:38:18.800 but it's a lot of it is psychological. So this works really well for a medication taper and people
01:38:25.900 can do it themselves. There's no like magic. I mean, I think we've covered a lot on CBTI and
01:38:33.920 let's now revisit the idea of the types of things that people should be on the lookout for that need
01:38:41.120 to be addressed first. So we haven't talked about sleep apnea. We haven't talked about restless leg
01:38:47.280 syndrome. What are the other things where you just want to have some sort of sign off that says,
01:38:54.540 hey, we've also confirmed that these things aren't present or what gets your suspicion roused that
01:38:59.640 says, hey, we got to look at something else because you're presumably not doing polysomnography on
01:39:04.600 everybody on the way in. How do you navigate that?
01:39:08.380 So I have the wonderful luxury of being able to look in people's charts and see who referred them to
01:39:13.580 me and why they are referred.
01:39:14.560 They can't be self-referred?
01:39:16.100 Everybody needs a referral of some kind and it can be from anybody, but any referral. A lot of my
01:39:20.520 referrals come from sleep disorder centers because they've already done all that work up and they
01:39:24.740 say, all right, it's none of these things. So here you go. If a patient tells me, I always ask a patient
01:39:30.380 like, oh, has your partner or anybody you've slept with ever told you that you snore or that you sound
01:39:34.980 like you're gasping for air in the middle of the night? I do have a bunch of those types of screening
01:39:38.560 questions. And I aggressively refer to colleagues with expertise in those areas before treatment
01:39:44.520 with me. A lot of times people have a CPAP and they say, oh, I don't really use it. I'm not sure
01:39:49.760 about that. And I say, well, I'm here to tell you that you should be sure about it and that you should
01:39:53.760 use it every single night. It doesn't fit. Cool. I'm going to make a call because we're going to get
01:39:58.300 it to fit. There's a different mask you can probably get. There's all these different issues that we can
01:40:02.320 tackle. It just sometimes takes making a phone call. And unfortunately, a lot of patients don't
01:40:08.940 have great follow through for their CPAP in terms of help using it and figuring it out. So sometimes
01:40:15.040 I have to just make that extra connection. The one thing I think I want to make sure that we put a bow
01:40:20.320 on also is this obsession with bedtime. I can make you wake up at any time by setting a very loud
01:40:28.240 alarm. I can anchor you into your day with a wake up time and that can be consistent every single
01:40:33.600 day. I cannot wave a magic wand and make you fall asleep at the same time every day. So when people
01:40:38.860 think, all right, I'm going to get a handle on my sleep, I'm going to go to bed at the same time
01:40:41.960 every night. No, no, no, no. Wake up at the same time every day. That's a much more important first
01:40:47.240 step. And if you're waking up at different times throughout the week, that is the first thing to fix.
01:40:53.740 Yeah. What degree of social jet lag do you tolerate? Just for folks listening, social
01:40:59.120 jet lag, meaning the experience of changing your sleep time during weekends, which could be akin
01:41:05.160 to jet lag if it differs by hours. In an ideal world, there would be zero, right? In an ideal
01:41:09.780 world, I wake up at seven o'clock in the morning every single day of the week. For an individual who
01:41:15.500 says, oh, but God, on the weekends, it's just so nice to not have to get up at seven. Do you say,
01:41:21.140 look, give yourself a 30 minute grace and that would still be considered perfectly healthy?
01:41:25.220 So during treatment, I tell people you need to wake up at the same time every day that ends in
01:41:29.440 DIY. So that means Monday, Saturday, Sunday. Yeah. That's all of them.
01:41:33.920 Yeah. That's during treatment. I have to check.
01:41:35.640 Yeah. Good. There is no room for negotiation during treatment. We're in the dictatorship.
01:41:40.840 But what I do teach people at the end of treatment is how to cope with the fact that life is going to
01:41:46.700 happen when treatment ends. It happens during treatment, but there's a lot that pauses during
01:41:50.620 treatment, to be honest. But let's say that you've got a major event on a Friday night. You're going
01:41:54.600 to a concert. Yes.
01:41:55.960 And you're going to be out way later than usual. What I tell people is, look, you need to pick
01:41:59.680 which day of that weekend do you want to suffer and which day do you want to feel good? Because
01:42:03.940 we can sleep in one day. You cannot sleep in two days in a row. That's going to take you off the
01:42:09.000 wagon. We're not doing it. So let's say Friday night you go to a concert and you want to feel good
01:42:13.320 on Saturday. Cool. Sleep in on Saturday. Sleep in by an hour on Saturday. Okay, fine. Go to bed on
01:42:19.380 Saturday night when you get tired. Spoiler alert, you're probably going to get tired past your usual
01:42:23.240 bedtime because you slept in. But then Sunday you have to wake up at your wake time and Sunday
01:42:27.440 you're going to suffer. But let's say you want to feel good Sunday. That means on Saturday you're
01:42:31.600 going to wake up at your usual time. Saturday is going to be a struggle bus, but you'll make it to
01:42:35.000 your bedtime and you'll go to bed at your bedtime. Then you'll feel better Sunday. So you just have
01:42:38.380 to choose. When do I want to do the suffering? The immediate day after?
01:42:41.040 So basically force the suffering into the narrowest place possible.
01:42:45.000 But you can choose because sometimes people don't want the suffering to be the next day.
01:42:48.380 They want it to be the day after. So you get to choose that. But I tell people, look,
01:42:51.640 don't sleep in more than one day in a row. It's going to mess you up. You're not really
01:42:55.000 getting quality sleep when you sleep in past your wake time. When it's been a pattern for
01:42:58.840 a long time, when you sleep in past your wake time, you're probably getting some extra stage
01:43:02.620 two sleep. You're not getting more deep sleep. That's for sure.
01:43:06.240 We're recording this on a Tuesday. Sunday, two days ago, I was flying back to Austin from LA
01:43:12.420 and the flight got delayed over and over and over and over and over again for reasons that are
01:43:21.260 so asinine they're not even worth describing. And then we finally got on the plane and taxied and
01:43:28.100 then the water was leaking out of the coffee machine. So we had to go back to get another
01:43:33.460 plane. I'm not making this up, but I can, I can only tell you how ridiculous this is.
01:43:39.520 The punchline of the story is we didn't get home till two in the morning, which is long past my
01:43:43.380 bedtime. So what would your strategy have been getting home at two in the morning prior to
01:43:50.900 Monday, a work day where you do have some leeway? I don't have to get up at six, which would be my
01:43:55.800 normal wake up time. Would you have said, just get up at six, stick with it and make it up by going
01:44:01.840 to bed a lot earlier Monday night? Or would you say sleep until eight? You'll probably feel better
01:44:07.220 than if you woke up at six. How would you handle that situation?
01:44:10.500 I'll say which day is more important for you to feel good on Monday or Tuesday.
01:44:13.660 Let's say I said Tuesday because I'm sitting down with you.
01:44:16.200 Well, then I would say probably try and not to sleep in too much so that you can go to bed at
01:44:20.760 your regular wake time on Monday. If you sleep in horribly on Monday morning, you're going to stay
01:44:25.280 up later Monday night and then you'll get up at your wake time today. You will have had shorter sleep
01:44:30.120 for today. It will have rolled all the way over.
01:44:32.320 That's actually what I did. So having not thought about this, I just slept until I think my wife
01:44:38.200 tried to get me out of bed at seven and I said, can you let me sleep till eight? So I didn't get
01:44:41.960 up till eight. But last night, you're right. I had a very hard time going to bed. It was like 11 o'clock
01:44:47.260 and I was still up meandering around.
01:44:49.400 Yeah. You just have to very carefully decide which day do you want to prioritize and that's how you make
01:44:53.540 that decision. So you have more control than you think is what's beautiful about that. And I just
01:45:00.000 remind people, you can never really make up for lost sleep that easily because sleep architecture
01:45:06.460 really matters. And when you're sleeping in, you're not getting more deep sleep. You're getting some
01:45:11.040 more maybe light sleep. And at worst, that's robbing you of maybe some of the deep sleep you
01:45:15.800 would have gotten the following night because you're on a circadian plan here. And we didn't
01:45:20.520 really talk about process S and process C. Maybe I can just briefly tell you what those two things
01:45:25.080 would be. Absolutely. Okay. So process S is sleep homeostasis. And that's this sleep pressure idea
01:45:31.420 that we are working on. Every day we build up sleep pressure until it's bedtime and then we
01:45:36.340 capitulate, we fall asleep. And then our sleep pressure drains throughout the night while we
01:45:40.360 sleep. And then in the morning, we build it up again the next day. And this is just adenosine
01:45:45.200 building up? Yeah. Think about it that way. And that's also why caffeine is problematic. So
01:45:49.300 caffeine blocks adenosine receptors. The caffeine crash when it wears off and then all the adenosine
01:45:54.360 floods the receptors and we experience that, oh, sleepiness. And that's why taking a nap is so
01:45:59.200 difficult because what napping does is it basically kind of deflates your balloon a little bit of your
01:46:04.080 sleep pressure. It robs you of some of that sleep pressure. So by the time you get around to your
01:46:07.720 normal bedtime, if you've taken a long nap, you've reduced how much sleep pressure you would ordinarily
01:46:12.240 have at that time. That's why napping can be dangerous. And then we have process C, which is the
01:46:16.820 circadian process. And that just marches on. It doesn't really care about your sleep pressure or how much
01:46:22.740 you've slept. I'm sure you've pulled an all-nighter, but when people pull all-nighters,
01:46:27.060 what they often will notice... How many all-nighters do you think I've pulled in my life?
01:46:30.220 Oh, hundreds. Yeah. I would need scientific notation to count them. It's so pathetic.
01:46:34.540 Yeah. It's a lot. The thing to note about that is that you're sleepy during the night when you're
01:46:39.180 pulling the all-nighter, but in the morning, you kind of have a burst of energy. And that's the
01:46:43.060 circadian part speaking up. And when we look at the sine curve of it, that's because your
01:46:48.300 temperature is coming back up. Your adrenal glands still make cortisol.
01:46:51.760 Right. So your circadian process doesn't really care much about the sleep pressure. It says,
01:46:56.740 oh, okay. If you line these two things up on a graph, they look like they talk to each other. They
01:47:00.200 don't. But these two processes really determine a whole lot about your sleep. And there are things
01:47:05.880 that we can do to support each of them. But CBTI really focuses on the sleep pressure aspect
01:47:11.780 by regularizing people's schedules. And then it supports the circadian aspect by some of these
01:47:19.560 little things that I talked about that I don't even know if you can't really call them standard
01:47:24.020 CBTI, like standardizing what time people are taking their medications, for example, doing things
01:47:29.340 that we know support circadian biology, not eating right before bed. In my perfect world, all of these
01:47:34.420 different Zykebers, which are timekeepers during the day, would be consistent from day to day.
01:47:39.040 You eat lunch every day at the same time, breakfast every day at the same time.
01:47:41.780 All of these things would support your circadian biology and probably improve your sleep.
01:47:46.640 Any rules about exercising? Do you have people that are showing up and you're going through your
01:47:51.780 intake and you realize based on their schedule, based on work, based on kids or other obligations,
01:47:59.240 the only time they're going to get their workout in is in the evening? And is that counterproductive?
01:48:04.520 Put it this way. If it is an issue, how do you adjust?
01:48:08.420 This is a really nuanced issue. I once had a patient who, a long time,
01:48:11.780 ago, who said, oh yeah, I take the 10 o'clock spin class in the Castro. I was like, oh, okay,
01:48:16.020 moving on. I assumed it was 10 a.m. I was wrong. And I learned that the next week when we were talking
01:48:20.780 about other things. But for some people, exercise at night is fine. For other people, it's super
01:48:27.940 stimulating. And it also really depends on what kind of exercise we're talking about.
01:48:31.740 I think one moderating variable here is also going to be level of fitness. If you take a person who's
01:48:37.380 extraordinarily cardiovascularly unfit and you put them in a spin class in the evening,
01:48:41.820 do you know it could take their heart rate quite a while to recover? You could probably provide me a
01:48:46.320 lot more information about that than I know. And what we know in order to fall asleep is that your
01:48:49.880 heart rate should be lowering. So if your heart rate is still elevated from a whole bunch of exercise
01:48:53.880 you just did, that's not going to help you. But if you're super fit and your heart rate recovers
01:48:58.160 really quickly, it might affect you less. So this matters. I think there was, for a long time,
01:49:03.940 this general suggestion to not exercise close to bedtime. I still think for the most part it applies.
01:49:09.700 But I think that it's important to think about what kind of exercise you're doing. If someone
01:49:13.260 tells me, oh, I'm going to a yoga class, I find this really relaxing and calming. It's a form of
01:49:17.560 stretching for me. Fine. Okay. This is the only time of day you can do it. You got a job, you got kids,
01:49:22.520 whatever. I'm not going to tell you to not go just because of the time of day that it is or
01:49:26.740 weightlifting or whatnot. But if you want to go to a HIIT class, I'm going to say, well,
01:49:30.580 can we not do it at 10 o'clock at night? I think it would really be great if we could move it earlier.
01:49:35.340 We try to do that. I do tell people, I have some patients who've come in and said, oh,
01:49:39.980 my body wants to wake up every day at seven o'clock, but I really want to go to this 5 a.m. spin class
01:49:45.580 every day. I'm like, okay, well, I understand. Exercise is very important. I'm a believer. Also,
01:49:51.760 your circadian biology has you going to bed at 11 and getting up at 7. And even if you're getting
01:49:58.420 up at 4.45 to get on your home spin bike to do this thing with this group, your body doesn't want
01:50:03.580 to go to bed until 11. And we're not going to be able to change that. So you're going to have to
01:50:07.180 make that cost-benefit analysis with, do you want to lose that much sleep to do that thing?
01:50:12.880 Yeah. My brother-in-law plays in a men's hockey league and you only get ice time late at night.
01:50:19.160 So I think they literally play Sundays at 11 p.m. or something. And he's always fried Monday because
01:50:25.760 pretty hard to play a game of ice hockey and then fall asleep after that. So I want to understand
01:50:32.860 more what the spectrum of CBTI looks like. I mean, your process sounds super dialed in,
01:50:40.700 but also it's quite bespoke. You've brought a lot of your own expertise to it and you've created a
01:50:46.780 system where you've got, we're going to do the intake. We're going to do these five sessions,
01:50:50.740 which I think are group sessions, the way you've described them. Then we do kind of the exit.
01:50:54.920 You bring so much rigor to it. Is that the way it is always done? Or are there CBTI therapists out
01:51:00.500 there who function like psychotherapists and they say, yeah, we're just going to engage with each other
01:51:05.840 until your problem is fixed. And we'll see each other once a week or maybe once every other week.
01:51:11.360 Everything you're doing sounds formulaic. And I say that not in a bad way. I think that's
01:51:15.280 probably a big part of its efficacy. Is that something people should expect
01:51:18.860 when they are going to a CBTI therapist? It's something people should ask for
01:51:22.980 before people start treatment. They fill out the Pittsburgh sleep quality index and they fill out
01:51:27.100 the insomnia severity index. And I tell them, look, we're going to fill this out when you're done
01:51:30.020 with treatment too. And we're going to see how this worked for you. We're going to actually take
01:51:34.100 measurements. What type of scores are you getting on the PSQI? I mean, it ranges from zero to 21.
01:51:39.680 I get all the way to 21. Yeah. And below five is considered no clinically significant sleep
01:51:45.760 problems. I relax that to six or seven, because if you have a prostate or if you're going through
01:51:48.980 menopause and have hot flashes, you're going to be elevated on that scale by no fault of your own
01:51:53.500 or your sleep's fault. And the insomnia severity index, I mean, yeah, we see all the way up to what
01:51:59.000 was it? 22, 23, something like that. So I see all the way up to the most severe levels in both of
01:52:04.800 these scales commonly. And the average point drops are huge in clinic. So I don't know if it was like
01:52:11.620 10 points in the insomnia severity index. Like it's very high, very responsive to this treatment.
01:52:16.580 But back to your original question is, I wish everybody did it by the book. I think there's a lot
01:52:22.020 of practitioners out there who want to do this by the book. I have a luxury to do it by the book
01:52:27.280 because I'm able to enlist help from my team to help me process sleep diaries every week and do
01:52:37.440 probably two hours of work outside of my clinic of prep for me. So they feed me my stuff that's been
01:52:45.120 built into the systems that I have. I'm prepping half an hour before clinic. I see everybody for an
01:52:50.220 hour and a half. And then I've got my notes, my templates and things. But I think that it is very
01:52:54.180 difficult to do CBTI when you're not seeing patients weekly because I look at weekly sleep
01:52:57.440 diaries and I make changes based on that. So when you find a CBTI therapist, I would say ask if you
01:53:02.200 can set up a time in the future with that therapist and see them weekly for a set of whatever, five to
01:53:08.160 eight weeks and put it on the calendar that way with them. If they say, oh, they don't have bandwidth
01:53:12.120 to do that for another month, say, okay, cool. I'll wait and then get on every week. And a lot of
01:53:16.780 practitioners also aren't going to necessarily score your sleep diaries for you. You can score them
01:53:21.220 yourself if you want to. I mean, it's not that difficult. If you just Google online, you can find
01:53:26.780 a sleep diary calculator and it's very easy to do the math yourself. There's a book that I really like
01:53:32.600 called Quiet Your Mind and Get to Sleep, written by Rachel Manber and Colleen Carney and Dick Bootsen
01:53:37.700 wrote the foreword. It's kind of a guided way through the treatment and you can use that workbook
01:53:42.760 yourself to do it. And you could also use that workbook when you're working with a provider.
01:53:47.320 But I think there are a lot of CBTI providers out there who can see you weekly and can do this.
01:53:53.700 You'll probably just have to do your back-end work with your calculations because they don't
01:53:57.420 have the billable time for that. They'll be busy during the sessions trying to teach you things.
01:54:01.460 I would also note that between my sessions with my patients, I make them watch very annoying videos
01:54:07.180 that I've made of myself giving a lecture about all of the science because I've found that if you
01:54:11.040 explain the science to patients, you'll get the adherence. Here's why we're going to do this.
01:54:16.020 People think, wait, I have problems sleeping. Now you're going to make me not go to bed?
01:54:19.660 This is not what I'm going for. And I have to explain to them, okay, here's why we do this
01:54:23.960 because this will ultimately get you where you want to go. But the principles of what I'm doing
01:54:29.020 are not at all bespoke. I'm doing the time in bed restriction, stimulus control, the cognitive
01:54:33.980 techniques, the relaxation techniques, and the sleep hygiene. Those are the five major components.
01:54:38.140 What is bespoke is the way that I set the wake time because that's not been standardized in
01:54:42.040 literature. The way I deal with standardizing medications, the way I deal with medication
01:54:46.320 tapers, some of the anxiety tools that I bring in like scheduled worry time, tracking due belief
01:54:51.800 during the day. I think that is actually pretty well incorporated into CBTI. But some of those
01:54:56.860 are a little bit more tilted toward my audience, which tends to be higher in anxiety. I build those
01:55:02.660 in. But otherwise, find someone on the website that we'll put in your show notes who knows how to do
01:55:08.600 CBTI. And I have a feeling you'll go far. The treatment works when you do it. And it doesn't
01:55:13.660 work when you don't do it, is what I tell all of my patients.
01:55:16.960 The book, Quiet Your Mind and Get to Sleep, you mentioned that that's something that people could
01:55:23.500 do in therapy. But you also mentioned that it's something people could just do on their own. So
01:55:27.320 if somebody is listening to this and they're thinking, A, I can't afford CBTI, or B, every practitioner
01:55:33.240 I've called said the soonest I can get in is nine months from now. If my choice is continue to
01:55:38.340 suffer or do something proactively, you would recommend that as a great strategy to start?
01:55:43.040 They can get that. They can try some of the apps. They're out there. I think they have less
01:55:47.400 traction currently. They're still in early stages, but try and help the rest app. But the Quiet Your
01:55:52.680 Mind and Get to Sleep book, people can do it by themselves. And I actually had a patient this
01:55:56.220 summer who was on the wait list. He got his intake and he was like, look, I'm fixed. I did the book.
01:56:01.380 It was awesome. But I still want to be in this group because I want to see what it's all about.
01:56:05.180 I'm not giving up my spot. And it was great having them in the group because they just
01:56:10.020 cheerlead everybody else and said, this works when you do it.
01:56:13.920 Any concerns with extreme temperature changes before bed? So people using sauna,
01:56:18.040 people using cold plunge, taking hot showers, hot baths. Subjectively, from my experience,
01:56:24.100 a sauna before bed really seems to help. Maybe it creates a bigger gradient in temperature drop as I
01:56:30.760 go from high body temp to low when I get into that super cold bed. But what is your experience
01:56:35.360 with that? And how do you manage it through the process?
01:56:37.400 Well, let's first take cold plunge before bed off the table. That's not a good idea because we know
01:56:41.860 that when you get in the cold plunge, it's immediately cold on your skin. But then once
01:56:45.120 you get out, your body is busy warming itself back up. And that's not what we want to be doing
01:56:48.520 right before bed. Then I'm going to come to the sauna part by saying that it's another
01:56:52.720 it depends. The outline that you just gave of the temperature gradient is beautiful. It makes a lot
01:56:56.800 of sense. For people who are naive to sauna, who get in a sauna and it increases their heart rate,
01:57:02.180 increasing your heart before bed. It might be the same problem as the exercise issue.
01:57:04.880 It might be the same problem as the exercise. Yeah, yeah, yeah. If they don't have the rapid
01:57:06.400 recovery. They don't have the rapid recovery. So that's something to learn about yourself.
01:57:10.540 And in fairness, I don't actually go straight from sauna to bed. It's usually sauna to 30 minutes
01:57:15.320 of Netflix to bed. That's going to be person to person. Another thing to keep in mind is that some
01:57:19.860 people who will go in the sauna at night then drink a whole bunch of water afterwards. Yes.
01:57:25.000 And then that ends up causing them to wake up more in the middle of the night. So it defeats the
01:57:28.560 purpose. That's a consideration also if that's an issue for you. But I would say just don't make it
01:57:34.220 too strenuous. Some people find that it's really helpful. I do best with it a few hours before bed
01:57:40.180 as opposed to right before bed. I think it's going to be a do what works situation because we don't have
01:57:45.900 enough data. But we are. I just started an NIH funded trial where we are looking at people who have
01:57:52.720 difficulty with falling asleep. And we are giving them whole body heating at home before bed. And
01:57:58.640 we're giving them cognitive behavioral therapy for insomnia through an app. And we're going to have
01:58:03.640 them do this whole home-based treatment that's going to combine a body-based heat treatment for
01:58:07.880 before bed with the CBTI treatment. And the idea here is what you explained, which is that by heating
01:58:14.120 you up right before bed, if we're heating up your hands and your feet, we're helping you actually
01:58:18.520 open the vasculature and dump some heat. It's going to create that gradient. And we think that
01:58:23.540 gradient might be important for people with the early kind of insomnia with falling asleep at the
01:58:27.120 start of the night. So we're going to see if that helps people using a sauna blanket type thing.
01:58:32.600 Ashley, someone listening to us for the last two and a half hours might assume that the only thing
01:58:36.740 you know about is CBTI. But it turns out that we've only scratched the surface of your area of
01:58:42.040 expertise. And there are other clinical areas that you have a lot of interest in that I think our
01:58:47.400 listeners would have interest in as well. The good news is we've, when I say we, I mean you,
01:58:52.700 you've delivered kind of a masterclass on a topic that I've wanted to know much more about. You know,
01:58:56.860 it's interesting. It's a bit of a black box because we send a number of our patients to CBTI therapy
01:59:01.900 around the country. And I would concur with what you said, which is based on their ability to comply,
01:59:09.640 the efficacy has been unparalleled, simply stated. As far as regular old doctors, I think we're
01:59:16.780 pretty good at helping people with sleep, given the nature of our practice and how much attention
01:59:21.100 we can pay. And therefore, I think by ourselves, we do pretty well. But when we can't, and we refer
01:59:27.180 to CBTI, I would have to think if there's been a patient who hasn't been helped. So that's great.
01:59:32.960 But truthfully, you've filled in all the gaps for me. And I think more importantly, I think you've
01:59:37.680 really helped listeners understand this. And I hope given people a lot of confidence,
01:59:43.320 because what I also take away from this is, there's really nobody who should be suffering
01:59:47.740 from insomnia. It's really not a necessary thing to suffer. There's things we might have to suffer
01:59:51.620 within life, but this isn't one. I think from very large percentage of the population, that's the
01:59:56.340 case. I'm afraid to say never, because you just never know. But there are so many, so many people,
02:00:01.840 countless, suffering from this who definitely don't need to be. The drawback is, we have kind of
02:00:08.060 run out of time to talk about a few other things that are really interesting, which is not uncommon
02:00:13.000 on this podcast, which means we're going to have to do a part two at some point to talk about eating
02:00:18.900 behaviors, thermal regulation, the impact that that has on depression or other things like that.
02:00:24.480 So apologies that maybe we spent more time on CBTI than we intended to. But as I kind of warned you
02:00:32.180 before we started, we love to just meander where the discussion goes. So is there anything else you
02:00:37.880 want to talk about on the CBTI front? I have a lot of notes on where I wanted to go, but I also
02:00:43.620 realized there's probably something I've forgotten, or there's an area you want to double click on?
02:00:48.420 No, I think it's important for people just to remember with this one that even if you don't
02:00:54.240 know what caused your insomnia, you can do this treatment. You don't have to have figured out,
02:01:00.680 oh, this is where it started, or this was the root of it all. You can start this treatment without
02:01:05.760 that knowledge, because this treatment is going to address what you're doing now that's actually
02:01:10.080 perpetuating the problem. And don't wait. There's never going to feel like a good time to do it.
02:01:16.000 Now is the best time. Your life is always going to be crazy. You're always going to have 50 more
02:01:21.180 things on the schedule than you wish you did. It's always going to be too busy. You're always
02:01:24.840 going to have events. Just do it now, because it's so difficult to live with insomnia and all of the
02:01:31.780 problems that it causes. I had this patient who was 87, who I finished treatment with last year,
02:01:37.660 and she just said, my, I wish I'd done this 40 years ago. Don't wait. Just do it. You won't regret
02:01:44.060 it. Are you under the impression that obviously people are waiting a long time to see you? That
02:01:49.700 probably speaks to how good you are and the resources that UCSF provides maybe in combination.
02:01:56.540 But if a person's listening to this and they're like, yeah, I wish I could work with Ashley,
02:02:00.940 but I just want to work with somebody. Do you have a sense of how large the CBTI community is
02:02:06.320 and how long a person should expect to wait? And do these therapists ever work via telemedicine
02:02:11.920 so that you have more opportunity to work with folks? I think that it is easier now to get than
02:02:18.000 ever, largely because of telemedicine. So I see patients all over California. I'm licensed in
02:02:22.900 California. Oh, so your eight people per bracket don't all physically come to San Francisco?
02:02:28.080 Nobody does. Great. I only see patients on Zoom now, which is actually a whole lot safer
02:02:33.120 because patients used to drive in, for example, from Fresno, they'd stay overnight in a hotel
02:02:36.720 in San Francisco. Yeah, they would just screw up the whole thing.
02:02:38.280 Screw up everything. Patients would have to fly in in some cases. It was nuts. But now I just see
02:02:43.140 people on Zoom, which is great. And there's a lot of versions of me who do that. By going to that
02:02:47.380 website, you'll be able to find a CBTI provider. And chances are they do telemedicine.
02:02:52.640 And there are just so many benefits. And one of the great pieces of news about that is that if
02:02:57.000 you live somewhere more rural now, it is instantly more accessible to you.
02:03:01.740 Although we have to hope that the providers, if you live in Iowa, we want to make sure they have
02:03:05.760 license in Iowa because you wouldn't be able to see somebody.
02:03:08.120 Right. They'll be licensed in Iowa. And there's also actually a growing and great thing called
02:03:14.060 PSYPACT, where I think 40 different states now are members of PSYPACT, where if you're licensed in
02:03:20.900 one state, you can be licensed in all of these states. Of course, California does not participate
02:03:24.220 because we're California. But it's getting easier and easier. And I do think that there's ways you
02:03:31.620 can start to do this on your own. If you get that book, if you try an app, you can actually do this.
02:03:36.800 You just have to remember that as special as each human is, you need to try and not feel like a
02:03:42.720 delicate flower with your insomnia. Just assume that you need to do this as it says you need to do it.
02:03:48.080 Well, Ashley, this was awesome. I learned a lot and I'm pretty sure everybody listening did. So
02:03:52.460 thanks for sharing and look forward to round two at some point next year.
02:03:56.060 Okay. Thanks.
02:03:57.800 Thank you for listening to this week's episode of The Drive. Head over to
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