Dr. David Perlmutter | This Past Weekend #187
Summary
Dr. Aaron Perlmutter is the author of Grain Brain, which has more than 1 million copies in print. He s also the host of the popular podcast, The Real Food Revolution. And he s a scientific kind of guy.
Transcript
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You know, every now and then an older man will come into your life
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and kind of teach you a little bit about yourself.
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Teach you what's going on inside of your body, deep in there.
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A lot of times, if you think about your stomach,
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So, you know, he ain't going to juggle for us, bro.
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But he'll definitely, he has more knowledge than I do.
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And so, that's why I'm excited that he is here today.
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which has more than one million copies in print.
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And, gosh, we wrote about it five years ago in Grain Brain.
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And at that point, that was pretty darn disruptive.
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I want to tell you that people suddenly, you know,
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you threaten, give us this day our daily bread,
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Well, they started, like, they were, like, losing it.
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And so, then I was like, what's going on here, you know?
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And, I mean, I've read more about it in your book.
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But I just wanted to hear, like, for a layman's, like, you know,
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like, if I saw gluten somewhere, would I know it's gluten?
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You know, you find it in condiments, in ketchup.
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Who's that serial killer that they just had that documentary come out about?
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But that said, I wouldn't say as aggressive as Ted Bundy.
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And, you know, when you face all of the chronic degenerative conditions that we face now in this world,
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the World Health Organization tells us that chronic degenerative conditions are the number one cause of death on planet Earth.
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We have to ask ourselves, what's the mechanism there?
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High sugar diet, not enough fat, things like gluten, food allergies.
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Those things literally have to come off the table.
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Now, I was reading in your book that – and this blew me away – that people who have diabetes are twice as likely to have Alzheimer's.
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We live in a country where 5.4 million of us have already been diagnosed with Alzheimer's, number one.
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Number two, there's no treatment, none whatsoever.
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And, matter of fact, in November of 18, a study came out in JAMA, the Journal of the American Medical Association,
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showing that the drugs that doctors are using to treat Alzheimer's are actually making them worse.
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I would say what you just said, that's the whole show.
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I mean, yet, you know, it's proved by the FDA it's useless and, in fact, making people worse.
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And people are spending a billion dollars in America to buy these drugs,
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putting their faith into these drugs to help mom or dad or husband or wife.
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I've been there with my dad who died of Alzheimer's.
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Yeah, my stepfather has it and my mother has too.
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We shout about what you said is that diabetes is related.
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Okay, you know, when 80 million Americans are diabetic or pre-diabetic, it's not a genetic issue.
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All of a sudden, that's just happened the past 50 years.
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And this is a disease of sugar and refined carbohydrates and less fat.
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And all of a sudden, everybody becomes diabetic.
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That may increase your risk for an untreatable illness, Alzheimer's, two to fourfold.
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So that's really, so if you have that in your family, I mean, these are really things you need to look out for because Alzheimer's can take, when does it usually kind of strike people, Alzheimer's?
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The beginning stages of Alzheimer's, what sets the stage for when you can't figure out what's going on around you, happens in your 20s and 30s.
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That it's not when you're my age and you suddenly can't remember the grandchildren's names and you name it.
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A lot of literature shows that if you look at markers of inflammation in the blood, they predict Alzheimer's 30 years ahead of time.
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And how do you get inflammation markers in your blood?
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So, it's not like, you know, people say, oh, I had a heart attack.
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Well, it's not like you're walking down the street, minding your own business, and then all of a sudden this thing attacks you out of the...
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Heart attack happens because you ate the wrong food, you didn't exercise, you have some genetic issues, et cetera.
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And I'm here to tell your audience that there are changes to make today to lower your risk.
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Because when you get there, when you get to a place where the doctor finally says, you've got this, there's nothing you can do.
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So, it's one of those things you have to start early.
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Well, when do you start setting the stage for diabetes?
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Actually, the changes begin before you're even born.
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When you're in utero, depending on mother's lifestyle choices, has a huge role to play on whether you're going to be diabetic,
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whether you're going to be overweight, which is a risk factor as well.
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So, I'm just thinking to myself, like, you know, if I'm just hearing this, you know, like a lot, because a lot of our listeners are 20 in their 20s and 30s.
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And, you know, some of them may be diabetic, may not.
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But there are usually a lot of good people, a lot of active people that want to make their lives better.
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So, what are, like, some easy ways out of the gate that you think, you know, is it just a rich thing?
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Sometimes I feel like just the rich can be able to, you know, really have a nice thing.
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It's just the rich, because you have to buy something.
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You've got to go out and buy a new pair of sneakers.
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Now, I don't know how rich you have to be, or you get them out of a bin, whatever you need to do, or you go barefoot.
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The bottom line is, step one is you've got to exercise.
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You've got to get your butt off the couch, and you've got to get at least 20 to 30 minutes a day of aerobics.
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If you can't do the math, then you really need to exercise.
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Well, the relationship between exercise, if you look at the epidemiology of it, shows those people who have higher rates of exercise have lower rates of Alzheimer's.
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But beyond that, exercise changes gene expression and codes for the body to produce a chemical called BDNF that tells your brain to grow new brain cells.
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So, you know, when I was, I hate to say when I was your age, but when I was your age, we were told that we were given a certain number of brain cells.
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And then as we, every beer we drank, we lost 30,000, whatever it was, you'd lose X number of brain cells.
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Because we didn't know that you grow new brain cells.
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By exercising, by taking a fish oil supplement, by using turmeric in your cooking.
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You can change your gene expression, grow new brain cells, and stave off Alzheimer's.
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And so do you think there's like a psychology to, like sometimes whenever you get into a path in life, whether it's an eating pattern or a, and you know it's detrimental, you know that the end is, doesn't end well.
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Is there some term for a psychology that makes you stay in that path almost out of spite or something?
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In fact, oddly enough, at the interview this morning, and the question was, how does mindset come into play for health decisions?
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And the more you change your mind and then do the right thing, the better that pathway becomes, the more reinforcing it will be.
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The other thing I talk about is inconvenient truth.
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You know, Al Gore talked about the inconvenient truth of climate change.
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I did a CBS This Morning program a couple of months ago, and they said, no, Dr. Perlmott has a new book.
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There's a new book talking about gluten and carbs and all that.
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But we reached out to the sugar industry, and they told us we should eat more sugar because decades of research.
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And in my mind, it was hashtag, why that's fantastic, hashtag WTF, right?
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So, in my mind, and then the lady gets on, she said, and then this morning I had, well, last night I had truffles because they're in season,
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truffle pasta with a jelly-filled donut or something.
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What I'm saying to your audience today is an inconvenient truth.
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It's comfort food because it stimulates the part of the brain for instant reward, dopamine surge, and you're momentarily content.
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But oddly enough, that diet distances you from the executive center of the brain that lets you make better decisions, plan for the future, be more compassionate and empathetic for yourself, for the next person, and for the planet.
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So, the more we distance ourselves from impulsivity, the better decisions we'll make, we'll get on an exercise regimen, we'll stay on it, and we'll choose to eat better foods that will enhance that, it's feed forward.
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That's really interesting because impulse is that, it's almost just like that dirty magnet that's in us, and it just wants whatever the easiest, quickest hit is.
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You need more of it because it's a dopamine surge, stimulates the opiate receptors in your brain, done.
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You know, you've done your thing, and now you need more.
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And the more you do it, the more that receptor needs to be stimulated.
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And so, choice is almost behind impulse a little bit.
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I mean, it's right there with it, but it's almost a gift to outride the impulse, I feel like.
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And then for a second, and then be able to, that's what I feel for me.
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It's like, okay, I just need a second and make a choice.
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The moment you just did that, what you just did, Theo, is you stopped dealing and responding to your amygdala brain, your reptilian brain, that said, I'm going to eat this, I'm going to do this, I'm going to punch this guy.
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That one moment is all the difference in the world.
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I'm going to think about, do I really want to eat this?
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Do I really want to, whatever the addiction may be, do I really want to do this?
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And now, make a more sophisticated, more human, rational decision to not do it.
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And does that get easier over time, doing that?
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The same chemical, brain-derived neurotrophic factor, BDNF, that you get from exercising.
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That allows you to connect to that part of your brain, so these things then stick.
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And the more they stick, the better you get at it.
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You need the other impulse because when you're back in your car out of the driveway and your
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mind sees in the backup camera a little kid on her bike, you hit the brake.
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You don't think, well, it'd probably be a good idea to hit the old brake pedal because this
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You need that impulsive activity to make the right decision quickly.
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But you don't need it when you're trying to figure out what foods to buy in the grocery
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You know, exercise is something that we don't have to, we don't want to find time for it.
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If you have to find time, you say, well, I'll squeeze it in between such and such and such
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And then those things suddenly take over a little more time.
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You didn't take time to make the food that's good for you.
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You ate some crap that you, you know, fast food.
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It's like our, you know, it's really, we're kind of in a tough, it's a tough system.
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It's like we've created this, you know, this sort of, I don't know if it's a comfort society
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or what it is, but it's, I mean, the system that we're in, in a lot of places, now I'll
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say in LA it's easier, it's very easier, it's much easier for me to stay healthier here.
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Then if I'm back in other places, like I'm from Louisiana, if I'm there, it is tougher,
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So Theo, my team said, you got to watch these, a couple of his podcasts before I come on
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And I got to tell you, this is, there's no segue here whatsoever, but that's what this
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And I didn't know what to expect, but I'm enjoying the heck out of it.
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I mean, one of the main reasons we'll get to it is, you know, I take antidepressants and
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a lot of times I get tired of, you know, it makes me feel like there's this, you know,
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there's something that's not natural that's out there that's added this connect, this taper
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to me, this chain, you know, like almost I'm a slave in a way to it a lot of times.
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And eventually, maybe one day, I would like to maybe not take them.
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Now, I'm not asking you for that, you know, direction now, but I do think, I start thinking,
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well, where are my other brains in my body, you know?
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And so then I started thinking about my stomach, you know, it's almost shaped in a way like,
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you know, it's, you know, your organs are almost like in a way for, to me or in my imaginative
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way, I work off of imagination first, kind of, it kind of is like a brain.
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So I'm thinking, well, how could I learn more about like what I put in my stomach that
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And so then I was talking to my producer, Nick, and I was like, we got to get somebody
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that knows about this so that I can learn more about it, you know?
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And so that's basically where I started thinking about, you know, about having you on.
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And then I only read about 60 pages of Grain Brain, but it was really fascinating to me.
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Even in that little bit of time, I found some things that were really interesting.
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And so I'm glad you're here today so I can talk to you about them.
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I mean, who knew that food has such an effect on every aspect of our lives?
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Let me get back to the imagination part, because I was really taken by that.
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You know, imagination is only a manifestation of connecting things that really happened.
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You know, your reality comes together to form imagination.
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First, I'm, I think, a husband and father first.
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So imagination is sort of like what happens during sleep.
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So during sleep, we connect real events, real memories, and we measure them against each
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So imagination is based upon your reality, things that you have experienced or have imagined
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Those things were based on things that you have experienced.
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And let's get back to this connection of the gut to the brain, not just the stomach.
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Which, interestingly, I've never heard anybody say was shaped...
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You're about to say, don't put words in your mouth, looks like the brain a little
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Maybe if I didn't say that, that's what I meant.
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But that said, depression is an inflammatory disorder.
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It's a disease characterized by higher levels of chemicals in your body that relates to a
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You get bitten by a mosquito, your hand gets inflamed.
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But those same inflammatory chemicals are upped, amped up in your body in relation to depression,
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in relation to Alzheimer's, autism, Parkinson's, coronary artery disease, diabetes, cancer.
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Which are so fundamentally related to not just your gut and things going on there, knowing
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that your gut bacteria determine what is called the set point of inflammation in your
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body, but even more importantly, to your food choices.
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Because you have to understand, you know, they say that when a woman is pregnant, she
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Theo, you're eating for a hundred trillion, right?
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Because of the future month, semen, all of that?
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So they're eating what you had for breakfast today.
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Those hundred trillion bacteria floating around in your gut.
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You know, is it a fiber-rich good food that we're going to be thrilled about?
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We're going to control the production of his brain chemistry.
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We'll get back to that because you mentioned that earlier, that the things you eat affect
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emotionally how you're able to relate to other people.
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Actually, that research was done right here in LA.
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Dr. Emron Mayer did some of the pioneering work on that.
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Wow, because so I could potentially be able to love people better and learn about myself
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We need to craft for you a diet that reduces inflammation.
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Well, why do we see other inflammatory disorders along with depression?
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Why do we see skin inflammation, joint inflammation, those types of things?
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Why do we see gross disturbances of gut bacteria?
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So the trick then for you and any of the other 47 million or 27 million Americans who are suffering
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We offer up a diet that's lower in its ability to produce inflammation.
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And that is a diet that's lower in sugar, lower in refined carbs, but has fiber, which
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People say, I'm going on a low-carb diet, and they ditch the fiber because it's a carb
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It's the last thing in the world you want to do.
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Eat olive oil, avocado oil, avocados, nuts and seeds, grass-fed beef, wild fish.
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Now, if you really want to push it, and you look like you probably want to push it, right?
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You really want to look into the ketogenic diet.
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Would do you a world of good, but be sure, and to any of your listeners, viewers who are
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thinking keto or doing keto, you've got to eat the fiber or you'll get constipated.
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And you've got to use potassium and magnesium or you'll get the keto flu.
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So many people bail on the keto diet because they don't do those two things.
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So you're saying, so a way to kind of to start and to fast track some of the things that
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you've been talking about that will help your system and my system.
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First, let me, because I'm slow, so I have to go through.
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I don't know if I'm sure my listeners are a lot quicker than me, but they always say I'm
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repeating stuff, but so, so a keto diet that we also add potassium and magnesium supplements.
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I mean, there are things, there are online brands that you can get.
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We don't have to, so a keto diet with those and then also fiber.
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Now, can that fiber be a supplement as well or does the fiber?
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So if we're talking about magnesium, let's be a little bit technical here.
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The center of the chlorophyll molecule is magnesium.
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So anything green that you eat has magnesium in it.
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If you really want the right kind of fiber for your gut bacteria, you use what is called
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They dilute it in the day, especially in World War II.
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But you can go to the health food store and stand at the counter and say, I want some prebiotic
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And they have prebiotic fiber that's made from acacia gum.
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It's almost twice chewed then if you get it, you know.
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But what we can do, though, is we can put a list of like a basic kind of starter set
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of diet under this YouTube that would be, I think, really helpful to people.
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But let's talk about more that involves inflammation that you can leverage for depression.
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Trying to do the same thing every day that you possibly can.
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Try to eat your last food at least three hours before you go to bed.
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So you want to be sleeping when you're sleeping, digesting during times that you're awake.
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You want to make sure you're getting good restorative sleep, like eight hours a night.
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Everybody's talking about, I want to limit stress so I don't do certain things.
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Stress can be on social media where we're being told we're not good enough.
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Because social media pounds you with ideology that we're not measuring up.
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That's the biggest stress inducer I think of in our modern times.
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where everybody else looks like they're having –
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Yeah, they're not sharing the truths a lot of times.
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it might even alleviate some people's stress to know that we aren't the same.
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Yeah, I guess in your lifetime you've probably seen –
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but I bet in your lifetime that you've seen –
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the way that social media and stuff has become that much of a stressor?
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And it has shocked me and my son, Austin Perlmutter, also an MD,
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to the extent that we've written a book about it.
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And that's coming out in January of 2020 called Brainwash.
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how the food that you eat speaks to your genes,
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giving your genes information to reduce inflammation
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not just for producing this feeling of low self-worth,
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but providing the quick clickbait answer to satisfy,
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look, I'm overweight, buy this thing, lose weight quickly.
00:27:39.780
If you think you need to buy stuff every day on Amazon
00:27:51.080
but don't be misled by what you're seeing on digital media
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What goes on in terms of manipulating your online choices
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is a situation that absolutely creates depression.
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you mean can immediately make me feel a certain way?
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as soon as it arrives the next day on Amazon Prime
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You have achieved a place where you don't need more.
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about caring for people who are different than you are
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it's amazing that so much emotion can come from
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i'll share this peace of mind i found i can feel it in my bones but it's gonna take a little time
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for me to set that parking brake and let myself
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unwind shine that light on me i'll sit and tell you my stories
01:40:57.620
ladies and gentlemen i'm jonathan kite and welcome to the
01:41:27.600
kite club a podcast where i'll be sharing thoughts on things like current events
01:41:32.040
stand-up stories and seven ways to pleasure your partner the answer may shock you
01:41:37.480
sometimes i'll interview my friends sometimes i won't and as always i'll be
01:41:42.760
joined by the voices in my head you have three new voice messages a lot of people are talking
01:41:49.180
about kite club i've been talking about kite club for so long longer than anybody else so great
01:41:55.420
hi sweetheart here's a deal anyone who doesn't listen to kite club is a dodgy bloody wanker
01:42:03.680
i'll take a quarter pounder with cheese and a mcflurry
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i think tom hanks just butt dialed me anyway first rule of kite club is tell everyone about kite club
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listen to podcasts or watch us on youtube yeah and yes don't worry my brad pitt impression will get better