00:00:30.000Okay. What about rates of depression and other side effects? And are there specific people who
00:00:36.180are more prone to this? Research indicates that girls who go on it during their teenagers,
00:00:41.300that this is something that can put them at risk for having major depressive disorder across their
00:00:46.300lifetime, even after they go off of it. Nobody's really paying attention to this, which is kind
00:00:51.860of BS. Yeah. I read some stories of women accidentally getting testosterone when they
00:00:57.860didn't need it and experiencing wild heightened sexual arousal do you know anything about that
00:01:03.400is that true this should be a good one welcome to my podcast thanks I'm excited to be here
00:01:12.960yeah this should be a good one um I've been interested in having this conversation for a
00:01:17.920while because I was on birth control from age 14 to 23 um originally for skin problems so I just
00:01:27.600like went to the doctor and they're like you know your skin's not great here's a birth control pill
00:01:31.740and I was like sweet no period that sounds fantastic um and then I think you talked to
00:01:38.040my mom right you're on her podcast I did I did yes it was great she told me as soon as I started
00:01:44.640taking it she said oh that pill made me really depressed and my response was I'm already really
00:01:50.900depressed. So I don't care. The 14 year old naive response. So I think this, this should be a good
00:02:00.760conversation. I've got a bunch of questions for you, but, um, I thought, yeah, I thought we should
00:02:07.120start off with just, is it true that the birth control pill can change your perception of who
00:02:14.720you're attracted to for a woman yeah you know it that is a possibility and this is something that
00:02:22.000sort of is rooted in research that's been done for about three decades now researchers have been
00:02:28.780finding that women's cycling their cyclically changing sex hormones play a role in who they're
00:02:35.780attracted to and in particular what this research finds is that when estrogen is high across the
00:02:41.920cycle that this is associated with an increased preference for cues related to testosterone
00:02:47.420markers and like masculinity and so for example at high fertility across the cycle when estrogen is
00:02:55.560high we find that women like deeper male voices they like more masculinized male faces they're0.52
00:03:02.800more likely to be attracted to cues of social dominance and so it's like women really sort of
00:03:08.240like like zero in on masculinity markers when fertility is high and when estrogen is high
00:03:15.400across the cycle and it was only more recently that researchers thought to ask you know what
00:03:21.560happens when we suppress women's estrogen levels with the birth control pill because when you take
00:03:27.240the birth control pill it prevents you from ovulating and it's that process of maturing
00:03:34.340egg follicles and getting an egg ready to be released, that causes the release of estrogen.
00:03:40.300That's one of the primary ways that our body produces estrogen. And the pill, by preventing
00:03:45.400ovulation, keeps estrogen levels really low. And then the pill that you take has very low levels
00:03:51.780of synthetic estrogen in it. And so researchers thought to ask, you know, do women who are on
00:03:58.040hormonal birth control, because their estrogen levels are low, does this lead them to prefer
00:04:02.920less masculinized male faces and voices and so on and so forth. And what they find is that that
00:04:08.860does appear to be true and that women who are on hormonal birth control have a preference for a
00:04:14.640less masculinized male face. They've done studies where they look at photographs of men who were
00:04:20.860chosen as partners by women who are on hormonal birth control or off of it. And they put the
00:04:26.380pictures of the men into two stacks and then they had them evaluated for masculinity as rated by
00:04:32.700you know just an outside group of people who didn't know which men were in which condition
00:04:37.140and then they also looked at more objective metrics of masculinity you can look at facial
00:04:43.300masculinity by looking at things like facial width to height which are correlated with testosterone
00:04:47.760levels and what they find is that the part the men who were chosen by women as partners that
00:04:53.620were on hormonal birth control is that they had less masculine faces relative to the men who were
00:05:00.060chosen by naturally cycling women, um, which is really mind blowing when you think about it.
00:05:06.240Yeah. Do you think that, so do you know what percentage of women say that are of like child0.75
00:05:12.620bearing age are on hormonal birth control? Yeah. You know, I don't know. Um, in some,0.84
00:05:20.280so like with college samples, for example, it's almost like 40% of women are on hormonal birth
00:05:26.540control because they're you know trying to get stay unpregnant while they're getting their
00:05:31.780degrees and that sort of thing um but in terms of like the overall population i'm i'm not sure
00:05:37.640but it's a sizable number i mean this is the number one demographic of women who are on it
00:05:42.880are women in their 20s and this is usually when women are choosing partners um and so that's you
00:05:48.420know potentially something that could be really consequential for women guys i wanted to talk to
00:05:53.400briefly about air purifiers and air quality. I've had various air purifiers for years and I knew
00:05:58.940air quality was important but I've learned a lot too much this year after getting sick from mold
00:06:05.580and I've settled on Aeroasis as my go-to air purifier. I actually reached out to them to see
00:06:11.360if they'd sponsor me because they're the best air purifier I could find and now I know how important
00:06:16.380they are. There are a few reasons why I chose Aeroasis. These filter down to 0.03 microns,
00:06:23.700which is actually important. It means they actually filter partial allergens and mold spores.
00:06:28.960And it was only recently that I realized most air purifiers filter down to 0.01 microns,
00:06:33.600which means they miss fragments, which make up the majority of allergens in the air.
00:06:38.540These also work on VOCs like new paint, gases, viruses, etc. I used to say if you guys have
00:06:45.120allergies get one of these, and definitely do, but everyone should actually have one or multiple of
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00:06:55.740Air Oasis is quiet, which is important because a lot of them aren't quiet, sleek, and filters down
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00:07:12.280at aeroasis.com and you can get 10% off with code MP. Enjoy the rest of this episode.
00:07:19.020Do you think that the correlation between, you said 40% of college students on the pill,
00:07:25.640do you think when they get into relationships, there's a higher likelihood of divorce?
00:07:30.780No, that's a really interesting question. And there's kind of two lines of research that point
00:07:35.860in different directions. The one line of research is some longitudinal research that's been done
00:07:41.940of newlywed married couples, and they followed them over time to look at changes in things
00:07:47.840like sexual satisfaction and relationship satisfaction over the course of the marriage.
00:07:54.160And one of the research questions that they thought to ask was, for women who choose their
00:07:59.840partners when they're on hormonal birth control, does their relationship and sexual satisfaction,
00:08:05.500for example, change if they discontinue? And so these researchers followed these women over
00:08:11.560time. And what they found was that when women who chose their partners on the pill discontinue the0.99
00:08:17.760pill, it is associated with changes in like how attracted they are to their partner and their
00:08:25.660sexual satisfaction and their relationship satisfaction. And what was really fascinating
00:08:29.940about it is that whether that got better or whether it got worse depended on how attractive
00:08:35.480their partner was so for women so for women who are partnered to attractive men when they went
00:08:42.980off the pill it was like the blinders came off you know and all of a sudden they're having these
00:08:47.300estrogen changes again and they're like oh yes right and they're more attracted to their partner
00:08:52.440and they um and they're more sexually satisfied and and then as a result of that they're also
00:08:57.500more satisfied in their relationship but they found that for women who are partnered to less
00:09:01.620attractive partner is that the opposite happened and that the women became less sexually satisfied,
00:09:06.700less attracted their partner, and then their relationship satisfaction decreased. And so it
00:09:11.700could potentially, you know, when we're choosing our partners on the pill, it could potentially
00:09:16.380nudge us into the direction of choosing somebody that we're not attracted to, but that doesn't
00:09:20.920always happen. And so, you know, it's like whether it makes it more positive or more negative when
00:09:26.140you go off of it a lot of times depends on the partner that you chose okay okay that makes sense
00:09:32.720so it's not just like doom and gloom for people who are on birth control and like oh no now I'm
00:09:37.740married and can go off of it I'm gonna see my partner in an entirely different light yeah no0.61
00:09:42.760totally I mean because when we look at the way that hormones affect like women's brains and they0.65
00:09:46.580affect women's behavior it's not like it's like gonna move you from here to over here instead it
00:09:51.740just kind of nudges it nudges our behavior in different ways or it might nudge you toward a
00:09:56.020you know more masculinized partner or more it might nudge you toward you know somebody who's0.97
00:10:00.260got this quality or that quality but it's um and for some women it will you know there is the
00:10:05.060unfortunate circumstance where it can nudge people in a direction that when they're off of it they
00:10:09.700don't feel attracted to their partner again but for a lot of women it's subtle and for other women
00:10:14.200it can actually make them feel better and like more attractive their partner once they're off
00:10:18.360of it and so yeah not doom and gloom it just all depends so so that's already a weird i guess you
00:10:25.940could call it side effect that people weren't expecting from from birth control right what
00:10:31.680about rates of depression and other side effects and are there specific people who are more prone
00:10:37.600to this is it random right no these are really great questions um there's definitely you know
00:10:44.440there's a lot of research that's pointing in the direction that being on hormonal birth control can
00:10:49.840increase your risk of anxiety and depression um and this risk seems to be particularly high for
00:10:57.200young women so um women who are like 19 and younger um seem to be the ones who overwhelmingly
00:11:03.740shoulder the burden of the greater mental health risks and researchers really don't know exactly
00:11:09.900why that is but i would assume that it has something to do with the fact that the brain
00:11:13.700is still developing, and that our ability to regulate our emotions is still developing at
00:11:18.120that time, and that changing that and changing our hormones isn't something that our mood and
00:11:24.860our sort of emotion regulation system is able to handle very well. There's also research that
00:11:30.560indicates that girls who go on it go on hormonal birth control during adolescence, so during their
00:11:36.440teenage years, that this is something that can put them at risk for having major depressive disorder
00:11:42.180across their lifetime even after they go off of it and this is something i know and this is
00:11:47.700something that's really concerning to me and it's very concerning to a lot of researchers because
00:11:52.340nobody's really paying attention to this um and there's so many doctors out there who do exactly
00:11:58.400what yours did and they prescribe hormonal birth control to teenage girls for things like acne or
00:12:04.700having irregular cycles or having bad cramps without understanding that when you take hormones
00:12:11.000and you shut down your brain ovary you know ovarian axis during development that this could
00:12:17.480potentially have long-term consequences in terms of brain development because our brain is still
00:12:21.980developing and our sex hormones play an important role in the pubertal transition that goes on and
00:12:28.080that post-pubertal brain development and very much influenced in important ways by our sex hormones
00:12:33.600and so that's something that um you know hasn't been very well studied there aren't nearly enough
00:12:40.260studies that have investigated the links of a teenage pill use on long-term outcomes. But the
00:12:46.600work that has been done, like I said, is not painting a very positive picture. And it seems
00:12:51.580like there's a potential risk there. And in terms of like who is affected, you know, and one of the
00:12:58.740risk factors as mentioned is, you know, being a teenager. And so we know that teenagers are at a
00:13:03.560greater risk of this than other women. But there seems to be even in adult women, like there is0.99
00:13:10.180an increased risk so many studies find that um there's a increased risk particularly with um
00:13:16.580the progestin only pill so that's the one that's now available over the counter um that one is
00:13:23.180like is always i mean almost almost every time they study it they find that being on that type
00:13:28.960of uh birth control is um predicts a greater risk of developing anxiety and depression um another
00:13:35.560Yeah, which is concerning to me. Like, I think it's great that we're allowing greater access to birth control, particularly in this sort of post-Roe dystopian world that we're living in at the moment, which I don't think is very good for women's health.
00:13:50.780But it's really concerning that women will take this without anybody knowing that they're on it, which could potentially be really devastating if you're a girl who just starts taking this birth control and developing a mood disorder.
00:14:08.360And you don't know what's wrong with you because most of the time when we develop a mood disorder from a drug, it's not like we think, oh, gosh, my drug is making me feel bad.
00:17:31.840so how did these how did these get like shuttled through and made available to everybody
00:17:37.420didn't they do testing and see any of these side effects so that at least when you got a
00:17:43.900prescription a doctor could be like hey you know it might work for you but if you're experiencing
00:17:48.460weeping every day and these like strong emotions maybe don't stay on it for 10 years and attribute
00:17:53.740it to something else like it could be the pill right yeah no i think that the reason that they
00:17:59.520made it available is because they wanted to have something that was available, that was reliable
00:18:03.680and easy to use, um, because of what happened with the Dobbs decision and overturning the,
00:18:09.720you know, row. And I think that it was like when they made, um, you know, they, they removed the
00:18:15.820guarantee of, um, legality of abortions for women, they figured, well, we have to do something to try
00:18:22.720to prevent women from getting into this position. And so I think that that was the decision that
00:18:28.420everybody sort of landed on is that this would be something that would be positive for women's
00:18:32.380reproductive health, which in some ways it is. I mean, preventing unwanted pregnancies is like
00:18:37.420one of the best things that we can do societally for women, just because like the biggest predictor0.83
00:18:43.340of ending up in poverty as a woman is a teenage pregnancy. And, and so like there's benefits that0.95
00:18:49.780way. But as you noted, I mean, the thing that makes me nuts, and of course, you know, I'm a
00:18:56.580psychologists so i'm gonna say this but people don't take mental health risks as seriously as
00:19:03.300they do physical health risks so for example you know like the the risk of a heart attack and stroke
00:19:08.940for example is seen as a safety issue right and so they're like oh well this you know um the the
00:19:15.440pill that has estrogen in it has a safety risk and so you know but like a mental health risk
00:19:21.540isn't seen as a safety risk it's just seen as sort of a nuisance side effect which is kind of bs i
00:19:28.160mean because when you think about it's like you think about how important your mental health is
00:19:33.040and you also consider like what the suicide rate is right now um and i mean you know depression
00:19:39.060like severe depression can be deadly um it can be because it causes people to take their own lives
00:19:44.900and it ruins the quality of lives and um and i don't know if this is what you were alluding to
00:19:51.020but I mean I know myself I was on the birth control pill for over 10 years myself and I used
00:19:56.500to have this narrative about myself where I believed that I was anxious and in a little
00:20:03.440melancholy and depressed and that's not me at all but I believe that to be true of myself because I
00:20:09.180was on it for all these years and I had these spells of anxiety and depression and then when
00:20:14.920I went off of it I realized that that wasn't me and then I didn't even really know who I was and
00:20:20.560that that was this totally different experience for me yeah i think i think people completely
00:20:26.880underestimate this i had a similar experience it was a little bit more complicated because i was
00:20:31.660also on an antidepressant and i started the antidepressant before i started the birth
00:20:36.340control so i already had the narrative that i was miserably depressed which is why i told my mom
00:20:41.900i don't care like we'll add a little depression on this mess of depression it's not going to make
00:20:46.620a difference anyway um but i don't like i i know also from having arthritis throughout my life
00:20:54.200i know that the depression was worse than the arthritis like i would have chosen the arthritis
00:20:58.980because you can deal with some pain like when you get a cold you can deal with not feeling good
00:21:05.520physically but when it hits your brain that is a completely other like that's a completely
00:21:11.340different story it's it's life-altering changes your perception of who you are like you said
00:21:16.980your perception of other people your perception of what you're capable of like it can just destroy
00:21:22.480your life and then you said you were on it for 10 years which is like that's an entire decade of your
00:21:27.240life yeah no i know that's terrible yeah no it is terrible and it really concerns me that you know
00:21:35.220when you have this available and like i said i feel very ambivalent about it because on the one
00:21:39.200And I think that we need to do everything that we can societally to help make sure that women who are trying to avoid pregnancy are able to do so just because of, you know, what we know about the risks of ending up in poverty and not being able to continue educational goals and so on and so forth for women who end up unexpectedly pregnant.
00:22:00.740But at the same time, having this pill available over the counter when nobody's being supervised and have other people watching them to say, hey, you know, you haven't really been yourself the last couple of weeks.
00:22:14.600What's going on is worrying because then these girls can end up in a situation where they're miserably depressed.
00:22:46.600So if people are friends with someone or if they're in a relationship with someone who's experiencing heightened anxiety and they're on the pill,
00:22:54.060are there resources that they can say hey maybe you should check out i mean obviously you
00:22:59.100and you have a book right that maybe people could go read and say just so you know this could be
00:23:04.480happening to you right no absolutely and in my book um which is this is your brain on birth
00:23:10.300control one of the things that i talk about is the different types of hormonal birth control
00:23:15.060because there's like four different generations of what are known as progestins which is that
00:23:19.780synthetic progesterone that's in the pill and there's like four different categories of those
00:23:24.540and so for example if a woman is experiencing depression and she's on hormonal birth control
00:23:30.540she can like look and see what's in hers and i've got a list on there of like popular birth
00:23:35.280controls that are out there and which you know which one tends to fall into what category and
00:23:40.200the best thing that women can do is just even start troubleshooting by going to their doctor
00:23:45.940and saying hey you know i'm on this pill i feel my mental health is in the toilet um i'm on0.91
00:23:52.200something that has a second generation progestin in it let's try a fourth generation progestin pill
00:23:57.840and then trying something different because these the synthetic progesterone that's in hormonal
00:24:02.940birth control is um is is different depending on what sort of category it falls into and they do
00:24:10.700very different things in the body um so just to give you an example a second generation progestin
00:24:17.140is actually synthesized from testosterone and because of that in addition to um stimulating
00:24:24.720progesterone receptors it also stimulates testosterone receptors and it also stimulates
00:24:30.880glucocorticoid receptors yeah so it has this really messy it can have really messy non-specific
00:24:36.280effects in the brain and in the body but then like a fourth generation progestin for example
00:24:41.600is synthesized from a diuretic called spiralectalone and it also it stimulates i mean it's just like
00:24:50.360everything is messy all these progestins are messy and they all do something a little bit
00:24:54.820different because they affect different receptors in the brain and to the rest of the body and so
00:24:59.440if you don't like a prescription of birth control that you're on but you really are motivated to be
00:25:05.340on hormonal birth control um i give really um i give recommendations like actionable recommendations
00:25:11.460for what women can do to then you know try to find something different that they like better
00:25:16.240and that their body responds differently too so is it dependent on the person or do you think that
00:25:22.340there are classes of birth control that have the least amount of side effects yeah they all have
00:25:28.880side effects um and all of them are sort of like different you know what it is so it's like for
00:25:34.040example with the second generation uh progestins for example like you tend to get um some side
00:25:41.920effects that are related to masculinization because of the testosterone receptors and so
00:25:47.180you'll get like skin breakouts and some women will like grow start growing facial hair and you get
00:25:52.540water retention um but then the fourth generation progestins are actually anti-androgenic and so
00:25:59.640your skin clears up and you look really good but then because it's blocking testosterone you a lot
00:26:06.240of times you can get decreases in libido and so it's like with each one of these you end up it's
00:26:11.980like pick your poison you know and so it's really about understanding what the different side effects
00:26:18.080are of these different types of progestins and then sort of picking the one that works the best
00:26:23.420for your body and then for your individual goals because for some women having clear skin is going0.88
00:26:29.300to be more important than it is for others for example and so women if you know that then you1.00
00:26:33.920can go and you can sort of start to do a semi-customization of your birth control based
00:26:38.740on your goals but to get at one of the other points you raised and that's that you know the
00:26:44.360way that each person metabolizes all of those different synthetic hormones is also going to
00:26:49.740differ and so for example you and i can be on the exact same formula of hormonal birth control and
00:26:56.280have vastly different responses. Like it could make, you could like ruin your sex drive and make
00:27:01.820your skin look amazing. And like, for me, it could make my skin look terrible, but not affect my sex0.91
00:27:07.760drive. It's like, and we're not unfortunately at a place yet with research where we can make good
00:27:14.040predictions about who's going to respond what way to what thing. And so a lot of it for women ends1.00
00:27:18.600up being a crapshoot. And I do like to think that the information I provide in my book provides a1.00
00:27:24.800starting point for allowing women to be able to at least have some footing in terms of where to
00:27:31.240get started in terms of what pill might work best for their body. I hope you guys had a fantastic
00:27:37.320Halloween. I dressed up like a cow. If you woke up feeling like garbage after because you drank
00:27:42.820and you don't normally drink, or maybe you do normally drink, but you still felt bad and you
00:27:47.060haven't tried my after-party pill, try it. I don't need to interrupt you for very long. It works to
00:27:52.120significantly reduce your hangover and help you break down acetaldehyde studies are available on
00:27:57.620the website i wouldn't be shilling this out if it didn't actually work because that is a great way
00:28:02.640to destroy your brand i wouldn't want to do that 30 day money well not just that i also don't like
00:28:08.780lying so these work 30 day money back guarantee code mp for 15 off that code won't be around
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00:28:21.020no fillers just pure ingredients like this one this is pure dihydromyricetin these actually work
00:28:28.880they work how you want them to work unlike birth control enjoy the rest of this episode
00:28:33.960so do you have kids or no kids i do i've got two okay uh do you have any daughters i do my oldest
00:28:42.580is a daughter so i have a 16 year old daughter okay so what like what was your if you don't mind
00:28:50.220what was your discussion with her because i know what my discussion would be but i'm so far
00:28:55.140i got so hurt from psych medications really i don't even know what birth control was doing
00:29:00.980because the psych medication side effects were so bad but yeah my like my response now which is
00:29:08.840probably i've gone so far in the other direction of just avoid everything they all have side effects
00:29:14.220who knows what they're doing to you and they're like sneaky side effects you won't figure out
00:29:18.260just don't take anything like that's my response but then it does come with the risk of
00:29:24.420unwanted pregnancy like it does um what like what do you tell people to do that's a really
00:29:33.180that's like well no i mean this this is the eight million dollar question right i mean this is the
00:29:37.920thing that i talk with my friends about and other researchers about um and in fact the last chapter
00:29:44.560of my book is called um what now a letter to my daughter and like yeah and it sort of discusses
00:29:53.040like what what to think about when you're thinking about whether to go on hormonal birth control or
00:29:58.540not and then if you're going to be on it like what type to to choose and like what are some
00:30:03.860of the considerations that you want to make when you're making that decision just because
00:30:07.920whether it's going to be right or not right for each individual woman is going to depend
00:30:12.660on her unique life circumstances and her goals and her values. And so I don't like to make any
00:30:18.740sort of indication about what anybody should do. Instead, I just like raise, like, what are some
00:30:22.740of the things you should think about when you are making a decision about going on birth control?
00:30:27.440And like, one of them is like, yeah, do I need to be on it? Am I in a sexual relationship or not?
00:30:33.780And, you know, like, what are my career goals? Like, how, how terrible would it be if I had an
00:30:39.600unprotected pregnancy right now because like for a married woman who's considering having kids soon
00:30:44.220anyway that might not be catastrophic but for an 18 year old it probably would be and so you know
00:30:50.160just sort of delineates what some of those questions are but I mean it's really hard like
00:30:55.560the thing that I think is terrible for women is that we are in this position where you know
00:31:01.400fertility regulation is the most important thing for us in terms of our ability to ensure that we
00:31:09.480can meet our educational goals and our career goals and um and we just don't have a lot of good
00:31:15.400options um for birth control i mean there's barrier methods like condoms and that sort of thing
00:31:20.660which you know work they're not perfect um but of course they're inconvenient and a lot of times
00:31:26.720people don't like them um then you've got and you've also got the um the uh uh diaphragm which1.00
00:31:34.820is another barrier method which is a little cup that goes in um you put it up in your vagina and1.00
00:31:39.160You snap it over the end of your cervix and, um, and that prevents, it serves as a barrier0.93
00:31:44.780between, you know, uh, the vaginal canal and then the cervix, um, which can prevent pregnancy
00:36:04.140At the same time, that's not what we need.
00:36:06.680What we need is something that's totally different.
00:36:08.620Because like you, it's like, I feel very much, you know, my background is in evolutionary biology.
00:36:14.380I understand our body as being this like really brilliant machine where we've inherited all of these traits that have helped our ancestors survive and reproduce.
00:36:23.920And, you know, our body is so nicely regulated on its own.
00:36:29.000and then to like do things like alter our hormones as a way to um to protect ourselves
00:36:35.380from pregnancy it's just not the best idea you know like staying away from all of that stuff
00:36:42.280i think is um if you're able to do it is is is good for the body it'd be nice in theory if there
00:36:48.740was a pill you could just take and like oh your skin clears up you feel fine nothing changes and
00:36:54.920you can avoid unwanted pregnancies until you're ready to have a kid. That sounds great. And that's
00:37:00.600how it's sold, right? That's basically how it's sold. Yeah. Ridiculous. So then is this a like
00:37:07.920progestin issue mainly? Like what happens when women go through menopause? And then I know a
00:37:15.180lot of women supplement hormones after menopause. Are they screwed then too? No. So here's the thing.0.99
00:37:22.840and it's it really is a progestin thing so that synthetic progesterone that's in hormonal birth
00:37:28.720control does all kinds of ridiculous crazy things in the body um just because the by the binding
00:37:36.780is non-specific as i mentioned like you'll have okay they'll stimulate testosterone receptors
00:37:42.260and they'll stimulate glucocorticoid receptors and they'll do all sorts of things that they're
00:37:46.640not really you know supposed to do and all of those things together create this experience of
00:37:53.200really weird side effects and the other thing that happens is just keeping women's own endogenous
00:37:59.840levels of sex hormones really low because essentially what you're doing when you're
00:38:03.400taking the pill is you're shutting down the brain ovary axis and you're not producing any hormones
00:38:08.480and that's a really unusual state for the female body to be in we are very much hormonal creatures
00:38:14.840and you know the the experience that women have when they're going through menopause is what
00:38:21.600happens like women oftentimes feel terrible because their hormone levels are really low
00:38:26.620and that doesn't feel normal for them and so their bodies feel bad and you know they get mood swings
00:38:32.680and they get vaginal dryness and some other things that are the result of having low levels of sex
00:38:37.680hormone and when women do a menopausal hormone therapy which is where they're taking synthetic
00:38:43.780hormones to try to increase their hormone levels to ease that transition, that oftentimes makes
00:38:49.700women feel a lot better than they do in the absence of it. And these hormones are pretty
00:38:55.840much biologically identical. And so when you're doing menopausal hormone therapy, you're taking
00:39:00.960a synthetic estrogen, which is very similar to what you have in the pill. The synthetic estrogen
00:39:06.020really isn't the problem. It's those synthetic progestins that are so goofy. And when you're0.90
00:39:11.620doing menopausal hormone therapy you um you actually take a bio-identical um progesterone
00:39:19.580so you actually take micronized progesterone instead of taking a progestin and so um that
00:39:25.500actually ends up being a lot better for women and just to give you an example of why that's true
00:39:31.040it like in addition to the fact that uh you know synthetic progestins will bind to hormone
00:39:38.000receptors that have nothing to do with progesterone and can make you feel kind of crazy um progesterone
00:39:43.840like the real deal progesterone that our body creates and then also is in micronized progesterone
00:39:50.120that women use in hormone therapy um when that gets metabolized by the body it actually releases
00:39:58.320a neurosteroid called allopregnanolone that is like really positive for mental health and so
00:40:05.500it's something that's very calming it um it helps to facilitate gabaergic activity in the brain
00:40:13.440which slows the brain down and makes it feel calm and relaxed and um so taking progesterone you get
00:40:19.680all these nice um neurological benefits that are calming and relaxing but with the synthetic
00:40:25.620progestins because they aren't even synthesized from progesterone you don't get that because when
00:40:31.420the body is metabolizing the synthetic progestin there's no neurosteroid there's no allopregnanolone
00:40:38.400there's nothing calming and relaxing instead you're just metabolizing a wonky version of
00:40:43.360testosterone for example in the ones that are made out of testosterone and so you don't get
00:40:48.920yeah no it's a totally different ball game than regular progesterone and sometimes i think
00:40:55.280progesterone our natural hormone and the one that women take in menopausal hormone therapy
00:41:00.040um gets a bad rap as being this like you know negative bad mood hormone um just because people
00:41:08.160are confusing it with the synthetic progesterone that's in the pill that makes people feel
00:41:12.480terrible okay i didn't know any of that i was like all the research i did on birth control and
00:41:19.940then i got you know like i said spooked out from spooked out to say the least from from other
00:41:25.680medications um i was worried about yeah what to do after menopause i mean do you go oh natural what
00:41:33.240if you're really suffering can you take any of those is it the same thing as taking uh birth
00:41:38.200control i had no idea that that was actually a different form of progesterone because i know
00:41:42.300when you get pregnant right your progesterone skyrockets and isn't that supposed to make you
00:41:47.980kind of feel calm during pregnancy so then how could it be the opposite with birth control why
00:41:53.580don't they just use the same couldn't they just use the same progesterone as they used to treat
00:41:59.380like post-menopausal symptoms right that you know i love that question because i had the exact same
00:42:05.280question like i went to um because i'm not an md so i'm not a doctor you know i'm a research
00:42:10.300psychologist so i study everything from the neck up and i was like why in the world are birth
00:42:16.780control pills made from this synthetic trash you know instead of like using this other thing that's0.72
00:42:23.340good. And here's the answer I was given. So the first part of the answer is it took a really long0.93
00:42:30.400time for researchers to be able to figure out how to make a solid, like a version of progesterone
00:42:37.680that you can take as a tablet or like as a pill that would pass the digestive tract and be able
00:42:45.160to be absorbed in the body. And so it took them a long time to be able to do that. And so it wasn't
00:42:52.340available micronized progesterone wasn't really available until i don't know how many years now
00:42:57.660but it was after birth control pills had sort of come on the scene right but then now that it is
00:43:04.240available and that we use it for things like menopausal hormone therapy and that sort of thing
00:43:08.700um why isn't why aren't we using it in in birth control and the answer i was given was that you
00:43:15.400would have to take it in such high doses to ensure that you're not going to allow your brain to start
00:43:23.360stimulating your ovaries because you have to have high levels of progesterone for your brain to not
00:43:28.660tell your ovaries to produce an egg which is how the birth control pill works is that you'd have0.95
00:43:33.620to take it in such high doses that it would make women just like way too tired and because it makes
00:43:40.320you like when you take synthetic or when you take a bioidentical progesterone it makes you sleepy
00:43:45.380and some other things and that you'd have to take it in such high doses that it might have an
00:43:50.220like intolerable side effects but that being said I've never seen it being tried you know I've never
00:43:56.620seen that I've never heard of anybody trying to do that and um and I and I think that it's a
00:44:03.280fascinating alternative to at least try that to see whether that's something that's possible
00:44:08.340um and and i don't know the answer to that like i said i'm not an md um but the mds i talked to
00:44:14.720when i asked them about that that that was their answer was that you know you you the dosage that
00:44:19.760you have to take is is really high to ensure that you're preventing pregnancy and that it would just
00:44:24.560not be something that was very well tolerated by most women but we haven't tried it and the0.80
00:44:31.360severe side effect of depression and choosing a slightly different mate is definitely better than
00:44:36.140being too relaxed yeah i know yeah yeah i know yeah no i don't understand like like i said
00:44:42.620that's always been my question and i was thinking like because i talked to a naturopathic doctor
00:44:48.180about this because i was thinking surely she would have tried this you know with a patient
00:44:52.900yeah and she was like no i just i i don't think that that would work because i think it'd be
00:44:58.260you'd have to take it in too high doses and i'm thinking to myself i want to like let's try that
00:45:03.300like let's try it that's weird yeah that's very strange yeah huh okay it'd be fun if like anybody
00:45:12.780who's listening to your podcast and they're um like sort of well-versed in the mechanics of
00:45:19.580birth control like in terms of uh how it like why that would be impossible i'm i'm just always
00:45:25.500looking for you know like why is that impossible because it seems to me like that's a great idea
00:45:29.980like why can't we do it and there's one answer that's also out there which is that you know you
00:45:37.100can't patent progesterone but you can patent progestin there we go yeah yeah and so i think
00:45:45.160that that might have something to do with it as well that's so infuriating okay this is going this
00:45:52.900is going in i had no idea about that makes total sense that makes more sense i always thought the
00:45:59.960birth control like i said kind of mimicked pregnancy and it was kind of made from bioidentical
00:46:06.960hormones because that's pretty much what you're told right yeah yeah and no and it's and it's not
00:46:14.840and it essentially it it makes it it has a hormonal profile that's similar to the second
00:46:20.260half of your menstrual cycle which is when after you've ovulated and your body is releasing
00:46:24.580progesterone and estrogen and so that daily hormone pill that you take every day is sort of
00:46:30.400mimicking that hormonal message it's relatively high levels of the synthetic progesterone or
00:46:34.640progestin and then low levels of estrogen and you take that every day and it makes the brain think
00:46:40.300that it doesn't need to stimulate the ovaries to release an egg but like you said i mean it's it's
00:46:46.060not progesterone it's a progestin and so it's stimulating progesterone receptors but then it's
00:46:51.640also doing a bunch of other stuff. And, um, and a lot of that other stuff is what makes women feel
00:46:56.140bad. Lovely. I think also part of the danger of like putting girls on it when they haven't1.00
00:47:05.180experienced cycles properly, like say when they're 14, cause I think I was, I literally
00:47:11.140think I started taking it like right after I got my period. Um, I didn't even know what a cycle
00:47:16.860felt like psychologically and so it wasn't until i was 23 and i stopped taking it and was like
00:47:22.640oh i can actually tell what the first week feels like and the second week i can feel what ovulation
00:47:29.920feels like i know when like i'm more inclined to work on the second half of my cycle where i'm just
00:47:35.640not like i'm not as interested like i'm gonna get down to business start working whereas the first
00:47:40.740half of the cycles i'm kind of like floofy and more social and things so and it was fun it was
00:47:45.600like oh that's what being females like i was just stuck in this weird work mode and with who knows
00:47:52.700how much extra anxiety for like almost 10 years from the pill that's so interesting yeah that's
00:48:02.040so interesting because i've heard from so many women that exact same experience and i had that
00:48:06.280exact same experience myself where i felt like i was i mean i went and i got my phd and i did all
00:48:11.800these things but I was just like yeah down to business you know just like do do do and then
00:48:17.000when I went off of it and I was like oh this is what it feels like to feel sexy like yeah
00:48:22.500like I didn't realize that I was missing out on that this all this time and and you're right I
00:48:29.540mean it's like not being able to experience that until you go off of it it's like what a shame
00:48:35.840yeah I got the weirdest thing I think that happened to me is I started to be able to
00:48:41.440then this was kind of gross too but around when i was ovulating i started to be able to smell people
00:48:46.380that i was walking by so i'd walk by someone and be like they have a smell i can smell i haven't
00:48:52.220smelled that smell before like what is that and i noticed it was when i was ovulating i could smell
00:48:57.060people which is i was like that's really animalistic and basic that i just didn't have
00:49:03.780before weird that's that's so interesting so there was actually a study done and i talk about this in
00:49:09.820my book where they find that very thing where women right near um what we call the fertile
00:49:15.680window so during that period of time right prior to ovulation um and and right at ovulation um0.98
00:49:21.740where you get increased in sensory sensitivity and women are like their ability to like detect0.92
00:49:29.320the scent of things like testosterone metabolites for example increases relative to what's seen0.96
00:49:36.060outside that cycle yeah and pill taking women don't get that they don't have that experience
00:49:40.860and they've also done some research with the pill looking at women's ability to identify
00:49:47.460genetically compatible partners like based on scent cues and generally what you find is that
00:49:53.540women right near high fertility that they can they exhibit a preference for the scent of men
00:50:01.660who are sort of immunologically genetically compatible and what you see is that like right
00:50:09.540near high fertility that women you know experience this preference for the scent of these genetically
00:50:14.200compatible men and for women who are on hormonal birth control there's nothing there's like no
00:50:19.100they never get that increased preference for genetically compatible men it said they have
00:50:24.120this like overall like flat line there's no preference at all and so this is another way
00:50:29.180that taking the pill could potentially get you in a relationship with somebody that you don't
00:50:34.700like and in fact one of the women i talked to in the process of writing my book was talking about
00:50:39.220scent and she ended up getting a divorce after um she discontinued the pill because she didn't
00:50:45.840like the way that her husband smelled and it was all that very thing that you're talking about
00:50:51.220um where she just didn't know it's not that he smelled bad he just didn't smell right
00:50:55.800yeah and that that could sound i'm sure people will take that the wrong way like oh how is that
00:51:02.040a reason to get a divorce but like if somebody smells good they smell really good like yeah
00:51:07.600yeah no but just idea yeah it's strong and and the idea that that i mean it's not so much like
00:51:13.700oh it's just smell but it was like yeah but i mean but that really plays an important role
00:51:18.960in attraction and and it's something that i don't think men understand because there's
00:51:23.480research that shows that you know women um scent is something that we're a lot more sensitive to
00:51:29.400and it influences our uh attraction and partner choice um to a much greater extent than it does0.84
00:51:35.760for men for men it's it's not even really uh something that's very important and women are
00:51:40.960a lot more sensitive to it and it does it it affects attraction is there any way for men to
00:51:47.460hack that like say they're suffering from oh also i wanted to talk you said there's the male birth
00:51:53.240control pill that seems to just flatten testosterone which like nobody is gonna want
00:51:59.120to take that like no man is gonna want to take that that was like literally when i first read
00:52:04.920the the news story about like they're creating this pill that lowers testosterone i'm like
00:52:09.780perfect have these people met men do they know any men like i don't know a single man who would be
00:52:17.500like yes please i'll take one of those yeah no way they're feeling a little too motivated
00:52:22.820feeling a little too motivated today let's take an anti-testosterone pill yeah no isn't that nuts1.00
00:52:29.020i just think it's crazy who's gonna take that okay yeah no not no one and nobody like women0.67
00:52:35.760wouldn't even want men to take that that seems like a terrible idea um no it does is there so0.66
00:52:41.820in regards to scent do you know anything about is there any way for men to hack this like is it just
00:52:48.020about raising testosterone and maybe they'll smell better are there things they can do that's a great
00:52:54.040that's a great question there was actually a study that came out just a couple years ago
00:52:57.700that showed that um for men who are like who don't like smell sort of good to women or whatever
00:53:06.520um they can actually improve their attractiveness to partners just by good old-fashioned cologne
00:53:12.060um and what research finds is that it's actually really fascinating is that if you have um men who
00:53:19.820are sort of on a range of um you know masculinity and so you have like the really masculine guys
00:53:25.260and you have guys who are less masculine um and you have women uh like rating their attraction
00:53:30.500to the man by looking at a photo and like smelling the man um what you get is that uh for men who are
00:53:37.820less masculine you get this increase in attraction just based on the presence of cologne um and it
00:53:45.620brings those men up to the same level as the masculine guys but for masculine guys it does
00:53:51.160nothing for them like it doesn't improve their attractiveness because they already smell
00:53:55.660attractive to women and so it seems like the sort of musky scent that tends to underlie um
00:54:02.880male cologne that you know it's like chemists have been like working on trying to make that
00:54:08.960smell just right to women for a really long time seems to be tapping into the to the right thing
00:54:14.640and it does seem to um attract women in the same way um as um as just good old-fashioned you know
00:54:22.120cues of uh testosterone within the the sweat glands that's so sneaky i know
00:54:30.680which is why it's like um if you're gonna get together with somebody like like maybe without
00:54:38.340cologne like how about no cologne like i just like let's spend some time together without cologne
00:54:43.680it's like spending time together without makeup let's just let's just see what's going on here
00:54:50.220that's so funny i was talking to uh graduate students of mine about tests relationship tests
00:54:56.540and that was one that the guys were like yeah you hang out with a girl with no makeup on and
00:55:02.480that's that's your test and now i love it so here's a female equivalent no cologne no deodorant0.72
00:55:07.280nothing just i need to smell you and that should be a test for women i like that i i completely
00:55:15.180agree uh that's great okay do you think in the future there's going to be any solutions here or
00:55:22.280is what people are playing with too complicated because of all the hormones involved and like
00:55:29.800trying to stop i feel like trying to stop a body from getting pregnant which is what bodies want to
00:55:36.900do really yes is so complicated that is it even like do you see it even as a possibility that
00:55:45.580doesn't come with a host of side effects in the future we have condoms i mean yeah everyone hates
00:55:51.820them but yeah exactly i think that there are you know i so i feel hopeful i think it's going to end
00:55:57.600up being something totally outside the box and so just to give you an example um of something that's
00:56:03.440actually being worked on right now and i don't know whether or not this is going to end up panning
00:56:07.500out to anything or not but there is this um apparently there's some like vitamin a derivative
00:56:13.040that our body is like some breakdown product of vitamin a that our bodies use in sperm production
00:56:19.380and it seems like it's only used in sperm production like they're doing a lot of
00:56:23.480research right now in animal models to make sure that it's only used and that the body doesn't need
00:56:28.980for other things um but so far it seems like really promising and that that's the only thing
00:56:34.480it's really used for and um and it's being used to test whether if you take something that blocks
00:56:40.620that does that prevent sperm production in men without having any other side effects
00:56:45.420um which would be really fascinating if that's true you know another thing is like i think it's
00:56:51.920going to take outside the box thinking like i'm just thinking like imagine that you have like
00:56:58.040some sort of a little thing that can in your full like a fallopian tube where the egg can like
00:57:04.480fall out or something like i think it's going to end up we're going to have to come up with
00:57:09.440something that's just totally different than anything that we've done before and um so i
00:57:14.400think that like outside the box thinking is going to be really important for this i mean i also think
00:57:19.600that there's a lot you know it's using uh so for example i use uh natural cycles which um uses the
00:57:27.060aura ring and so it tracks my basal body temperature and it's really good at um like
00:57:33.220telling me when and i know also when i'm in the fertile window i'm just i'm pretty in tune with
00:57:39.040my body but i think that technology and things that measure daily body temperature and apps and
00:57:45.600that sort of thing that can help isolate the fertile window for women so that way they can
00:57:50.460you know do something else for birth control or use some form of birth control just during the
00:57:55.320periods of time when they need it over the cycle I think is also like one of the ways that we're0.99
00:58:00.760headed um and so I'm hopeful that um our ability to successfully predict when women are in their
00:58:08.160fertile window gets better so that way it's more reliable after women and they can feel more
00:58:13.100confident and that is a birth control method but um yeah I feel hopeful that something's out there
00:58:18.700but it's gonna have to get away from hormones I mean there's just no way to not profoundly affect
00:58:25.140the entire organism you know with that when you change a person's hormonal profile it's just
00:58:30.600impossible i feel like that's the right track because there's only like how many days a month
00:58:37.220are women actually fertile like five and then if you have so say you have sex eight days before
00:58:45.980the sperm's in you long enough you know there's still a likelihood you can get pregnant or is
00:58:52.880it really this five-day window of having sex that you can get pregnant yeah yeah yeah it's about five
00:58:57.580to seven days in which um yeah that that sex that you have on that day could potentially lead to
00:59:03.840conception and it's five to six five to six days prior to ovulation and then within 24 hours of
00:59:10.700ovulation um and so after you it's been 24 hours since you've ovulated you're home free and you're
00:59:17.420generally home free about the first week of your cycle so the first day of bleeding for about seven
00:59:23.320days you're generally home free but that's not always the case sometimes the women will have a
00:59:28.040you know short um follicular phase and that sort of thing and which is why it's always a little0.99
00:59:32.820tricky to just give a rule of thumb like that because you could give a rule of thumb and then
00:59:37.320somebody ends up pregnant so um but as a general rule of thumb not to be used as birth control
00:59:42.460um that first seven days of your cycle are usually reasonably safe after you know you've
00:59:47.640ovulated if it's been 24 hours you're generally safe for about almost two weeks so okay so i've
00:59:54.940got i have a couple of questions one when you're taking this say you're taking the birth control
00:59:59.400pill that stops your cycle for like three months or it does something for three months and then it
01:00:05.460says there's like a bunch of sugar pills you take those for a week and you bleed is it actually
01:00:10.560uterine lining given the fact you haven't ovulated like what's going on there yeah no it's not uterine
01:00:16.420lining because you're not what is it it's just blood it's just essentially when you have a
01:00:21.460hormone crash in your body that um sends a signal to your um to your endometrial layer to to start
01:00:28.920to um shed and and and release blood flow and so that's really all that that is there's a little
01:00:35.400bit of uterine lining because like there's a tiny bit of estrogen and especially in these combination
01:00:39.880pills and estrogen is proliferative and causes the cells in the uterine lining to proliferate
01:00:45.940and so there's a little bit of it but not much so the the period that you have on the pill isn't
01:00:52.320really a period it's um it's just a withdrawal bleed okay that's yeah okay i and then the other
01:01:02.900question that's also why like oh i was gonna say that that's that's another reason why um you know0.62
01:01:08.120for a lot of women who have been on the pill for a while and then they go off1.00