Clavicular - How to ACTUALLY Lose Face Fat Fast (No BS Guide)

00:00:00.000 Reddit True Tide aka the ultimate good. So what exactly is a GLP-1 agonist? Well the agonism of

00:00:05.880 the GLP-1 receptor is going to help us decrease the calories in portion of the equation by

00:00:10.740 increasing hunger control and appetite suppression. It's also going to have its effect on gastric

00:00:15.060 emptying which means you're going to stay full for a little bit longer. So having a lesser meal

00:00:18.900 frequency is much more favorable for people trying to lean max. Slower gastric emptying will also

00:00:23.960 reduce post-meal glucose spikes and decrease demand on insulin secretion. So obviously if

00:00:28.780 you're able to eat less to satiate yourself you're going to be having a much easier time

00:00:33.240 staying in a calorie deficit and maintaining that calories in calories out equation that

00:00:38.280 we're talking about. GLP-1 agonism is also going to help improve insulin sensitivity as it enhances

00:00:43.500 glucose dependent secretion. So unlike samalgotide, terzipitide and retitrutide, the dual and triple

00:00:49.700 incretins, also have the biggest effect on the GIP receptor. So retitrutide's obviously got the

00:00:55.480 strongest affinity for the GIP receptors than any of the other GLP-1 agonists. While retitrutide is

00:01:01.640 primarily a GIP agonist, it also has the GIP-R agonism. So you get an array of benefits that come

00:01:06.560 from that that the monoagonists like samalgotide obviously don't produce. So GIP-R is highly

00:01:11.840 synergetic with GLP-1-R. So if you don't know what GIP-R is, well it's highly synergetic with GLP-1-R.

00:01:18.260 So it's got that really good anti-nausea effect. So that explains why people don't really get sick on

00:01:22.820 retitrutide and manjaro while they do on ozempic. So in basic terms, semaglutide basically makes you

00:01:28.580 not eat because it makes you too sick to eat. Whereas retta and terz have a lot more specific

00:01:32.720 mechanisms of action that actually work through your brain, your pancreas, and actually work on

00:01:37.600 adipose tissue itself. So GIP-R seems to be highly active within the adipose tissue itself. So it has

00:01:42.960 an extremely positive effect on insulin sensitivity and also increases blood flow to the adipocytes.

00:01:49.080 So GIP-R even helps with nutrient partitioning, which you've probably heard about if you looked

00:01:52.740 into trend before, since it enhances the lipid oxidation. This is obviously a different mechanism

00:01:57.660 than tremolone, so don't take that out of context. I was just using terms that you might have been

00:02:01.660 familiarized with before. Retta has these super unique properties that the single and dual agonists

00:02:06.900 do not have. So terz has a super small affinity for the GIP-R receptor before you yell at me in the

00:02:12.060 comments, but it is nowhere near retta. So it's not even worth mentioning. So let's talk about the

00:02:17.100 glucagen agonism. So this is where retta really stands out from the dual and single incretins.

00:02:21.860 So glucagen is going to increase your heart rate and cardiac output. So what does that mean?

00:02:26.720 More calories out. This also has an effect on your satiation and has another mechanism of slowing

00:02:31.880 your gastric emptying. So this is really, really like putting all the puzzle pieces together.

00:02:36.200 Glucagen has a multitude of effects on the liver and adipose tissue. In the liver, it increases

00:02:40.620 liver cell survival and increases liposis, which creates free fatty acids. It also increases

00:02:45.820 thermogenesis and liposis, which further drives the free fatty acids to convert into ketones.

00:02:51.100 So this is literally forcing your body to burn excess fat. Most studies will indicate this is

00:02:55.740 probably going to increase your caloric expenditure by about 150 to 200 calories.

00:03:00.500 So let's talk about the muscle retention on retitutide versus the other GLP-1s. Obviously

00:03:05.040 all the GLP-1 agonists are going to lead to fat loss, but we don't want to just lose weight. We want

00:03:09.360 to lose adipose tissue and retain as much lean muscle mass as we can. Ozempic has a horrible amount

00:03:14.980 of muscle loss, with an average of 23 to 30% of the weight loss being from muscle itself.

00:03:20.020 Rizipatide is slightly better, but it's still in the neighborhood of 15 to 30%. But retitutide

00:03:25.000 is only at 8 to 12% of the weight loss coming from muscle mass. This is mostly due to the

00:03:30.220 glucogen and GIP anabolic signaling. So obviously retitutide is going to be the most conducive

00:03:35.480 to bodybuilding, luxmaxing, whatever you want to call it, because you're going to retain

00:03:39.140 the most lean muscle. Let's talk about what this stuff can do for your lipids. This is especially

00:03:43.300 important if you're someone who's using gear. So retit has demonstrated significant effects

00:03:47.540 on lipid metabolism in clinical studies, improving key markers associated with cardiovascular and

00:03:52.940 metabolic health. Retitutide will help you get into that 99th percentile to your blood

00:03:57.240 work and put an end to all the diet 30 copes. It also has benefits for your liver, which is

00:04:01.600 especially good for people like me running Accutane, Orals, and a bunch of other compounds.

00:04:06.240 So the studies show it has a lot of benefits on your liver, with a 40 to 60% reduction in liver

00:04:11.200 fat due to the enhanced fatty acid oxidation. This basically means the liver burns fat for energy

00:04:16.520 instead of storing it. That's very good for you. So there's not really a consensus on dosing

00:04:21.560 protocol, but I'll tell you what I did. I was already on GLP-1 agonist, so I could get

00:04:25.480 away with starting a bit higher. I started at 7.5mg, now I'm on 10mg. If you're already

00:04:31.020 on a GLP-1 or used a GLP-1 before, you could get away with this as well. But if you haven't

00:04:35.980 adapted to GLP-1 signalings, I would start at around 2.5mg for the first week, then the

00:04:41.560 week after that you could bump your way up to 5 and see how you're feeling. The only side effect

00:04:45.480 I noticed is that my arms felt a little bit weak for some reason the day after I first

00:04:49.640 dosed retatrutide, but besides that, I had no nausea or no issues like that.

00:04:54.640 So to conclude, retta is definitely one of the best looks maxing peptides, but without

00:04:58.200 a doubt, I don't think that there's anything that's on par with this stuff. I know it's

00:05:01.940 expensive, but if you could get your hands on it, it is truly a miracle compound.

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Clavicular - December 14, 2025

How to ACTUALLY Lose Face Fat Fast (No BS Guide)

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