00:29:18.840I'll make a disclaimer, which is my passion is not beauty, but it was a necessary, let's call it evil, because so many people ask about it.
00:29:28.380And so I took it upon myself to learn.
00:29:30.140And I learned from two plastic surgeons, one in Switzerland and one in Japan.
00:29:34.220And both of these people have been doing stem cells for cosmetic purposes for 10 years.
00:29:39.240So they have tons of experience and they're plastic surgeons and they're cosmetic doctors.
00:29:42.860And you're probably wondering why are surgeons doing this?
00:53:51.280so all we can do is build resiliency and try to do build the right do the right tools so that we
00:53:57.620can deal with these toxins a sweatsuit sweatsuit i hadn't heard of that yeah that seems very useful
00:54:04.500and it's not like sauna or infrared technology or is it kind of infrared no no it it i i think it
00:54:11.120just helps your body to sweat more i don't know the exact mechanism okay but yeah i'm gonna look
00:54:15.200into that that's cool wow okay okay and then you talked a little bit about how expensive and like
00:54:21.420i had tons of comments about like these are so expensive like how do normal people afford this
00:54:25.460but can you talk a little bit about the price of stem cells and yeah i mean the price is actually
00:54:31.400cheaper than when i came on last year yeah so that's progress so that's progress right like
00:54:35.160i think last year we said it was like 25 000 for an iv and now it's like 15 to 20 yeah and why is
00:54:41.200it going down because the manufacturing is improving so we're able to use something called
00:54:44.960uh bioreactors where you can grow more stem cells at a cheaper cost and it's gonna and that's just
00:54:51.200gonna get better now let's i think in another year or two once we have the second generation ones
00:54:55.800and those are at scale then those one will be the expensive ones for like you know let's say
00:55:00.160celebrities pro athletes people who have more money and then the first generation will be even
00:55:04.140more affordable so i think it's only going to keep getting better and i think the best analogy
00:55:09.200now that i think about it is like those do you remember those plasma tvs but when they first
00:55:13.780came out they were like some of them were like fifty thousand dollars or hundred thousand dollars
00:55:17.880like now you can get them for like five hundred bucks yeah so it's like you know this happens
00:55:22.500this is the technology of innovation but there has to be early adopters who are willing to say
00:55:27.760okay not i mean yes there's there's a selfless component of saying okay i'm willing to do this
00:55:33.640because i can afford it and it's going to pave the way for future for more people to do it in
00:55:37.620the future and i think that's the mindset of a lot of people i have i know you know obviously a lot
00:55:42.300of celebrities and people i treat their that's kind of their mindset too is that they know this
00:55:45.840exactly because they know this is going to help humanity down the road similar to how electric
00:55:50.060vehicles like elon musk when he had to get tesla in 2010 he had to he gave it to like near leonardo
00:55:55.600dicaprio like tom cruise like he was just he just like take a free car because he wants them to just
00:55:59.700drive it and promote it and but once but the car back then was pretty crappy like it didn't go very
00:56:04.800far. It was just a bunch of batteries taped together. Like it was so, but the technology
00:56:09.760improved and paved the way for better technology. And I think that's the same thing with cell and
00:56:14.140gene therapy. So gene therapy already like, yeah, again, it is expensive right now, but I believe
00:56:21.140in like five years, the folistatin will be probably like a fifth of the price. Oh, wow. Yeah. That's
00:56:27.260really cool. Where have you been? Cause you've been around talking to doctors and seeing what
00:56:31.900like the most cutting edge therapies are where in the world have you been do you think that's
00:56:35.740advanced the furthest i mean in my space definitely asia like i think uh china japan
00:56:44.760and even so i haven't been to south korea yet but i'm planning to go this summer
00:56:49.180are probably are probably the leaders when it comes to tissue engineering cell therapy and gene
00:56:54.960therapy and like really moving this field forward more from a clinical translation side as opposed
00:57:00.900to just research like i think u.s still has some of the in canada too has some of the best and
00:57:05.120brightest scientists but the problem is our regulators don't allow for a lot of the stuff
00:57:10.120that we're actually making this amazing breakthrough science on because they're so strict
00:57:14.260and stringent about what can be done when i don't think it's i think i think the japanese models
00:57:21.020make so much more sense to me which is saying that okay we have a regulatory framework and we
00:57:26.480know that these things are safe they're very unlikely to cause harm and they have a lot of
00:57:31.380potential benefit so why don't we allow that for people who want them that i mean it's very logical
00:57:36.260to me and that's why stem cells have culture expanded stem cells which are the ones that are
00:57:41.140manufactured and grown for like three or four weeks which are illegal in the usa are having
00:57:45.880around in japan for 10 years so i think it just it just makes you question why are the japanese
00:57:51.980doing this to like a such a large scale their own population yeah exactly exactly and whereas here
00:57:58.820it's like well do we really want people to get better or you know who's who's controlling the
00:58:03.600regulatory bodies right yeah is this just so is it just the pharmaceutical companies i mean there
00:58:09.700i think um dr john abraham he was on lex friedman's podcast and he has a great he has if you guys if
00:58:17.100people who really want to dig into this it's an hour and a half long and he has a book called
00:58:20.420sickening but the gist of it is i'll give you the high level summary pharmaceutical companies have
00:58:25.500some there's something called a revolving door which is like big pharma go the the people who
00:58:31.120are ceos and executives there often go into fda go to scdc and they kind of just like revolve
00:58:36.580around those different places so in basically in like insiders from the industry are going into
00:58:42.220the regulatory body so what's so who's who are they going to help out they're going to help out
00:58:45.800their buddies that they know right so it just that's just unfortunately the way it is that's
00:58:50.880that's the biggest problem but there's many many other problems in terms of like how these things
00:58:55.240get approved how they're how pharmaceutical companies are good at getting approvals because
00:58:59.400they know how to work the system because some of the drugs don't even do much like like there's so
00:59:04.480many examples but even like there's one called trulicity which is like this um diabetic drug
00:59:10.280and there's something called number needed to treat which is like how many people actually
00:59:13.960need to take this to have a real meaningful benefit on their health and like number two
00:59:18.300you need to treat was something like 327 that means 327 people so if you give it to a thousand
00:59:22.820people like three benefit three people will actually benefit from it and this is fda approved
00:59:27.240and because they were just able to do like you know just have a large enough sample size to make
00:59:32.020it statistically significant and like just they know how to work the system basically and john
00:59:36.480abraham he he really talks a lot about that abrahamson or yeah his book is called sickening
00:59:42.100though but it's a really good eye-opening topic sounds yeah that sounds like somebody good to get
00:59:48.360on too that's awful that's awful i feel like when you grow up especially when you grow up in canada
00:59:52.760at least when i grew up i was like i was told that we had the best health care system in the world
00:59:56.680over and over and over yeah best in the entire world and then when it really came down to it
01:00:01.820when i needed surgery like now yeah it was like oh this is terrible and they're like yeah you might
01:00:07.200want to go to india we were literally considering that we had a visa booked to get me an ankle
01:00:12.700replacement in india because there was a three-year waiting list in canada and i was like
01:00:16.920suicidal with pain india that's and i was like okay well i i thought the same thing it's funny
01:00:24.780you said that because that's what i was like oh i'm so lucky i get to go to a canadian med school
01:00:28.420i'm going to the best i'm getting the best medical education in the world and and honestly a lot of
01:00:33.460My colleagues still think that and that's probably part of the reason why they're not really understanding what's happening in medicine because they think they've already learned everything there's to learn and what they need to learn is being distilled from a very specific lens of guidelines and those guidelines are coming from specialists and those specialists have ties more often than not to pharmaceutical companies because they're the top tier specialists and they always get poached and recruited by these pharmaceutical companies.
01:01:01.100and so the guidelines are essentially just a reflection of a bunch of specialists who
01:01:05.780might be the top in their field but unfortunately they have their own biases and so
01:01:10.480so if you if you if you actually look at it and you start going outside of the guidelines then
01:01:16.020you're considered not doing things that are standard of care and then that's where it becomes
01:01:19.680hard for a lot of doctors to be like and so obviously what i'm doing is not standard of
01:01:24.200care in canada but in other countries it is and in other countries people are benefiting plus
01:01:29.420for me, it's always a discussion now with my patients. I offered them, I'm like, okay, well,
01:01:34.900you can get a hip replacement or you can try this stem cell procedure. These are the success rates.
01:01:40.620This is the pros and benefits. And you can decide. Most of them rather do the less invasive procedure
01:01:45.180that can potentially have the same outcome. Why not? And why shouldn't they have that option?
01:01:50.660And the fact that they have to travel outside the country to do that is kind of baffling to me,
01:01:54.760but that's the current state. So let's talk about joint replacements for a second.
01:01:59.420how far like what how far gone is a patient that you've seen that's recovered like for me from just
01:02:04.700to give you an example like when i got my hip replaced it was there was no cartilage and it
01:02:09.660was bone on bone and the bone was starting to break down so it was at that point yeah can you
01:02:13.900resolve something that far gone or have you seen that or is it like before that yeah that is we
01:02:21.820have had cases with that and now especially because we just got hydrogels so hydrogels oh yeah i think
01:02:28.700think i talked about them last year and now we have them finally uh so we have the first generation
01:02:33.000of hydrogels which is essentially a scaffold in which the stem cells are embedded into but this
01:02:38.560hydrogel specifically is really cool it's from it's a company in portugal and what it does is
01:02:43.280you can inject it using just a regular syringe so you don't have to do surgery but then it cross
01:02:47.740links once it goes inside so it forms this like scaffold mesh how do you how do you know where
01:02:53.200to put it just by the injection yeah we use ultrasound guidance to go right into the joint